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authorMădălin Ionel Patrașcu <madalinionel.patrascu@mdc-berlin.de>2022-06-28 00:34:03 +0200
committerRicardo Wurmus <rekado@elephly.net>2022-10-27 15:56:40 +0200
commitfe2be9c0cf4d4327f8ef9eda1668de76cbc4fca7 (patch)
treef448febcd8d19311f6887007b29b3efd408e1df0
parent9b337c2735f522a8fcaa1e7972df4a76f97d29b8 (diff)
gnu: Add r-bandits.
* gnu/packages/bioconductor.scm (r-bandits): New variable.
-rw-r--r--gnu/packages/bioconductor.scm38
1 files changed, 38 insertions, 0 deletions
diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 3a53ebdf95..c8a15c5123 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -2498,6 +2498,44 @@ downstream analysis, such as differential gene expression or transcript
usage.")
(license license:gpl3)))
+(define-public r-bandits
+ (package
+ (name "r-bandits")
+ (version "1.12.0")
+ (source (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "BANDITS" version))
+ (sha256
+ (base32
+ "1423djb7cij68y0q2dcp8q7lrcn2fxjn6d25v4qy3w00b2w8ppg9"))))
+ (properties `((upstream-name . "BANDITS")))
+ (build-system r-build-system)
+ (propagated-inputs
+ (list r-biocparallel
+ r-data-table
+ r-doparallel
+ r-dorng
+ r-drimseq
+ r-foreach
+ r-ggplot2
+ r-mass
+ r-r-utils
+ r-rcpp
+ r-rcpparmadillo))
+ (native-inputs (list r-knitr))
+ (home-page "https://github.com/SimoneTiberi/BANDITS")
+ (synopsis "Bayesian analysis of differential splicing")
+ (description
+ "BANDITS is a Bayesian hierarchical model for detecting differential
+splicing of genes and transcripts, via @dfn{DTU} (differential transcript
+usage), between two or more conditions. The method uses a Bayesian
+hierarchical framework, which allows for sample specific proportions in a
+Dirichlet-Multinomial model, and samples the allocation of fragments to the
+transcripts. Parameters are inferred via @dfn{MCMC} (Markov chain Monte
+Carlo) techniques and a DTU test is performed via a multivariate Wald test on
+the posterior densities for the average relative abundance of transcripts.")
+ (license license:gpl3+)))
+
(define-public r-biocversion
(package
(name "r-biocversion")