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-rw-r--r--gnu/packages/bioconductor.scm58
1 files changed, 58 insertions, 0 deletions
diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index e890542b31..43f33721df 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -9140,3 +9140,61 @@ variables.To assure a good level of reproducibility a post-test filter is
available, where we may set the minimum effect size considered biologicaly
relevant, and the minimum expression of the most abundant condition.")
(license license:gpl2)))
+
+(define-public r-catalyst
+ (package
+ (name "r-catalyst")
+ (version "1.14.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "CATALYST" version))
+ (sha256
+ (base32
+ "13af7c4irx1f5yqi32k7kj661vzg32wn3dnps7r9pjijfl4drhrh"))))
+ (properties `((upstream-name . "CATALYST")))
+ (build-system r-build-system)
+ (propagated-inputs
+ `(("r-circlize" ,r-circlize)
+ ("r-complexheatmap" ,r-complexheatmap)
+ ("r-consensusclusterplus" ,r-consensusclusterplus)
+ ("r-cowplot" ,r-cowplot)
+ ("r-data-table" ,r-data-table)
+ ("r-dplyr" ,r-dplyr)
+ ("r-drc" ,r-drc)
+ ("r-flowcore" ,r-flowcore)
+ ("r-flowsom" ,r-flowsom)
+ ("r-ggplot2" ,r-ggplot2)
+ ("r-ggrepel" ,r-ggrepel)
+ ("r-ggridges" ,r-ggridges)
+ ("r-gridextra" ,r-gridextra)
+ ("r-magrittr" ,r-magrittr)
+ ("r-matrix" ,r-matrix)
+ ("r-matrixstats" ,r-matrixstats)
+ ("r-nnls" ,r-nnls)
+ ("r-purrr" ,r-purrr)
+ ("r-rcolorbrewer" ,r-rcolorbrewer)
+ ("r-reshape2" ,r-reshape2)
+ ("r-rtsne" ,r-rtsne)
+ ("r-s4vectors" ,r-s4vectors)
+ ("r-scales" ,r-scales)
+ ("r-scater" ,r-scater)
+ ("r-singlecellexperiment" ,r-singlecellexperiment)
+ ("r-summarizedexperiment" ,r-summarizedexperiment)))
+ (native-inputs
+ `(("r-knitr" ,r-knitr)))
+ (home-page
+ "https://github.com/HelenaLC/CATALYST")
+ (synopsis "Cytometry data analysis tools")
+ (description
+ "This package is Cytometry dATa anALYSis Tools (CATALYST). Mass
+cytometry (CyTOF) uses heavy metal isotopes rather than fluorescent tags as
+reporters to label antibodies, thereby substantially decreasing spectral
+overlap and allowing for examination of over 50 parameters at the single cell
+level. While spectral overlap is significantly less pronounced in CyTOF than
+flow cytometry, spillover due to detection sensitivity, isotopic impurities,
+and oxide formation can impede data interpretability. We designed
+CATALYST (Cytometry dATa anALYSis Tools) to provide a pipeline for
+preprocessing of cytometry data, including i) normalization using bead
+standards, ii) single-cell deconvolution, and iii) bead-based compensation.")
+ (license license:gpl2+)))