Merge branch 'master' into staging

98 files changed, 9579 insertions, 2424 deletions

diff --git a/NEWS b/NEWS
index b1eaf896db..27ac11c13a 100644
--- a/NEWS
+++ b/NEWS
@@ -74,10 +74,11 @@ Please send Guix bug reports to bug-guix@gnu.org.
 *** The installer now has a crash dump upload mechanism
 *** Emacs now supports native compilation
 *** GRUB bootloader now supports chain-loading
-*** The GNU Shepherd was upgraded to 0.9.2
+*** The GNU Shepherd was upgraded to 0.9.3
 *** The init RAM disk honors more arguments—e.g. ‘root’ and ‘rootflags’
 *** ‘guix system image’ can now generate WSL images
 *** The mcron task scheduler logs now contain the jobs exit statuses
+
 ** Programming interfaces
 *** Package input fields can now plain package lists
 *** G-expressions can now be used in build phases
diff --git a/doc/guix-cookbook.texi b/doc/guix-cookbook.texi
index f371364746..af08d4ed54 100644
--- a/doc/guix-cookbook.texi
+++ b/doc/guix-cookbook.texi
@@ -21,6 +21,7 @@ Copyright @copyright{} 2020 Brice Waegeneire@*
 Copyright @copyright{} 2020 André Batista@*
 Copyright @copyright{} 2020 Christine Lemmer-Webber@*
 Copyright @copyright{} 2021 Joshua Branson@*
+Copyright @copyright{} 2022 Maxim Cournoyer*
 
 Permission is granted to copy, distribute and/or modify this document
 under the terms of the GNU Free Documentation License, Version 1.3 or
@@ -95,6 +96,7 @@ System Configuration
 * Auto-Login to a Specific TTY::    Automatically Login a User to a Specific TTY
 * Customizing the Kernel::          Creating and using a custom Linux kernel on Guix System.
 * Guix System Image API::           Customizing images to target specific platforms.
+* Using security keys::             How to use security keys with Guix System.
 * Connecting to Wireguard VPN::     Connecting to a Wireguard VPN.
 * Customizing a Window Manager::    Handle customization of a Window manager on Guix System.
 * Running Guix on a Linode Server:: Running Guix on a Linode Server.  Running Guix on a Linode Server
@@ -1380,6 +1382,7 @@ reference.
 * Auto-Login to a Specific TTY:: Automatically Login a User to a Specific TTY
 * Customizing the Kernel::       Creating and using a custom Linux kernel on Guix System.
 * Guix System Image API::        Customizing images to target specific platforms.
+* Using security keys::          How to use security keys with Guix System.
 * Connecting to Wireguard VPN::  Connecting to a Wireguard VPN.
 * Customizing a Window Manager:: Handle customization of a Window manager on Guix System.
 * Running Guix on a Linode Server:: Running Guix on a Linode Server
@@ -1883,6 +1886,65 @@ guix system image --image-type=hurd-qcow2 my-hurd-os.scm
 
 will instead produce a Hurd QEMU image.
 
+@node Using security keys
+@section Using security keys
+@cindex 2FA, two-factor authentication
+@cindex U2F, Universal 2nd Factor
+@cindex security key, configuration
+
+The use of security keys can improve your security by providing a second
+authentication source that cannot be easily stolen or copied, at least
+for a remote adversary (something that you have), to the main secret (a
+passphrase -- something that you know), reducing the risk of
+impersonation.
+
+The example configuration detailed below showcases what minimal
+configuration needs to be made on your Guix System to allow the use of a
+Yubico security key.  It is hoped the configuration can be useful for
+other security keys as well, with minor adjustments.
+
+@subsection Configuration for use as a two-factor authenticator (2FA)
+
+To be usable, the udev rules of the system should be extended with
+key-specific rules.  The following shows how to extend your udev rules
+with the @file{lib/udev/rules.d/70-u2f.rules} udev rule file provided by
+the @code{libfido2} package from the @code{(gnu packages
+security-token)} module and add your user to the @samp{"plugdev"} group
+it uses:
+
+@lisp
+(use-package-modules ... security-token ...)
+...
+(operating-system
+ ...
+ (users (cons* (user-account
+               (name "your-user")
+               (group "users")
+               (supplementary-groups
+		'("wheel" "netdev" "audio" "video"
+                  "plugdev"))           ;<- added system group
+               (home-directory "/home/your-user"))
+              %base-user-accounts))
+ ...
+ (services
+  (cons*
+   ...
+   (udev-rules-service 'fido2 libfido2 #:groups '("plugdev")))))
+@end lisp
+
+After re-configuring your system and re-logging in your graphical
+session so that the new group is in effect for your user, you can verify
+that your key is usable by launching:
+
+@example
+guix shell ungoogled-chromium -- chromium chrome://settings/securityKeys
+@end example
+
+and validating that the security key can be reset via the ``Reset your
+security key'' menu.  If it works, congratulations, your security key is
+ready to be used with applications supporting two-factor authentication
+(2FA).
+
 @node Connecting to Wireguard VPN
 @section Connecting to Wireguard VPN
 
diff --git a/doc/guix.texi b/doc/guix.texi
index eaecfd0daa..e547d469f4 100644
--- a/doc/guix.texi
+++ b/doc/guix.texi
@@ -60,7 +60,7 @@ Copyright @copyright{} 2018, 2021 Oleg Pykhalov@*
 Copyright @copyright{} 2018 Mike Gerwitz@*
 Copyright @copyright{} 2018 Pierre-Antoine Rouby@*
 Copyright @copyright{} 2018, 2019 Gábor Boskovits@*
-Copyright @copyright{} 2018, 2019, 2020 Florian Pelz@*
+Copyright @copyright{} 2018, 2019, 2020, 2022 Florian Pelz@*
 Copyright @copyright{} 2018 Laura Lazzati@*
 Copyright @copyright{} 2018 Alex Vong@*
 Copyright @copyright{} 2019 Josh Holland@*
@@ -1409,7 +1409,7 @@ when transferring files to and from build machines.
 File name of the Unix-domain socket @command{guix-daemon} is listening
 to on that machine.
 
-@item @code{overload-threshold} (default: @code{0.6})
+@item @code{overload-threshold} (default: @code{0.8})
 The load threshold above which a potential offload machine is
 disregarded by the offload scheduler.  The value roughly translates to
 the total processor usage of the build machine, ranging from 0.0 (0%) to
@@ -3423,19 +3423,25 @@ The @var{options} can be among the following:
 @itemx -i @var{package} @dots{}
 Install the specified @var{package}s.
 
-Each @var{package} may specify either a simple package name, such as
-@code{guile}, or a package name followed by an at-sign and version number,
-such as @code{guile@@1.8.8} or simply @code{guile@@1.8} (in the latter
-case, the newest version prefixed by @code{1.8} is selected).
+Each @var{package} may specify a simple package name, such as
+@code{guile}, optionally followed by an at-sign and version number,
+such as @code{guile@@3.0.7} or simply @code{guile@@3.0}.  In the latter
+case, the newest version prefixed by @code{3.0} is selected.
 
-If no version number is specified, the
-newest available version will be selected.  In addition, @var{package}
+If no version number is specified, the newest available version will be
+selected.  In addition, such a @var{package} specification
 may contain a colon, followed by the name of one of the outputs of the
 package, as in @code{gcc:doc} or @code{binutils@@2.22:lib}
-(@pxref{Packages with Multiple Outputs}).  Packages with a corresponding
+(@pxref{Packages with Multiple Outputs}).
+
+Packages with a corresponding
 name (and optionally version) are searched for among the GNU
 distribution modules (@pxref{Package Modules}).
 
+Alternatively, a @var{package} can directly specify a store file name
+such as @file{/gnu/store/...-guile-3.0.7}, as produced by, e.g.,
+@code{guix build}.
+
 @cindex propagated inputs
 Sometimes packages have @dfn{propagated inputs}: these are dependencies
 that automatically get installed along with the required package
@@ -4834,6 +4840,15 @@ invocation can be expensive: it may have to download or even build a
 large number of packages; the result is cached though and subsequent
 commands targeting the same commit are almost instantaneous.
 
+@quotation Note
+The history of Guix is immutable and @command{guix time-machine}
+provides the exact same software as they are in a specific Guix
+revision.  Naturally, no security fixes are provided for old versions
+of Guix or its channels.  A careless use of @command{guix time-machine}
+opens the door to security vulnerabilities.  @xref{Invoking guix pull,
+@option{--allow-downgrades}}.
+@end quotation
+
 The general syntax is:
 
 @example
@@ -8080,20 +8095,20 @@ following forms:
 @item (delete @var{name}@dots{})
 Delete from the inputs packages with the given @var{name}s (strings).
 
-@item (append @var{package}@dots{})
-Add @var{package}s to the end of the input list.
-
 @item (prepend @var{package}@dots{})
 Add @var{package}s to the front of the input list.
+
+@item (append @var{package}@dots{})
+Add @var{package}s to the end of the input list.
 @end table
 
 The example below removes the GMP and ACL inputs of Coreutils and adds
-libcap to the back of the input list:
+libcap to the front of the input list:
 
 @lisp
 (modify-inputs (package-inputs coreutils)
   (delete "gmp" "acl")
-  (append libcap))
+  (prepend libcap))
 @end lisp
 
 The example below replaces the @code{guile} package from the inputs of
@@ -8104,7 +8119,7 @@ The example below replaces the @code{guile} package from the inputs of
   (replace "guile" guile-2.2))
 @end lisp
 
-The last type of clause is @code{prepend}, to add inputs to the front of
+The last type of clause is @code{append}, to add inputs at the back of
 the list.
 @end deffn
 
diff --git a/gnu/build/file-systems.scm b/gnu/build/file-systems.scm
index 15b8f73312..66ca22d6ea 100644
--- a/gnu/build/file-systems.scm
+++ b/gnu/build/file-systems.scm
@@ -1127,7 +1127,7 @@ corresponds to the symbols listed in FLAGS."
       (('read-only rest ...)
        (logior MS_RDONLY (loop rest)))
       (('bind-mount rest ...)
-       (logior MS_BIND (loop rest)))
+       (logior MS_REC (logior MS_BIND (loop rest))))
       (('no-suid rest ...)
        (logior MS_NOSUID (loop rest)))
       (('no-dev rest ...)
diff --git a/gnu/installer/services.scm b/gnu/installer/services.scm
index 6c5f49622f..d08bab47fd 100644
--- a/gnu/installer/services.scm
+++ b/gnu/installer/services.scm
@@ -159,25 +159,32 @@
          (base     (if desktop?
                        '%desktop-services
                        '%base-services))
-         (heading  (list (vertical-space 1)
-                         (comment (G_ "\
+         (service-heading (list (vertical-space 1)
+                                (comment (G_ "\
 ;; Below is the list of system services.  To search for available
-;; services, run 'guix system search KEYWORD' in a terminal.\n")))))
+;; services, run 'guix system search KEYWORD' in a terminal.\n"))))
+         (package-heading (list (vertical-space 1)
+                                (comment (G_ "\
+;; Packages installed system-wide.  Users can also install packages
+;; under their own account: use 'guix search KEYWORD' to search
+;; for packages and 'guix install PACKAGE' to install a package.\n")))))
 
     (if (null? snippets)
         `(,@(if (null? packages)
                 '()
-                `((packages (append (list ,@packages)
+                `(,@package-heading
+                  (packages (append (list ,@packages)
                                     %base-packages))))
 
-          ,@heading
+          ,@service-heading
           (services ,base))
         `(,@(if (null? packages)
                 '()
-                `((packages (append (list ,@packages)
+                `(,@package-heading
+                  (packages (append (list ,@packages)
                                     %base-packages))))
 
-          ,@heading
+          ,@service-heading
           (services (append (list ,@snippets
 
                                   ,@(if desktop?
diff --git a/gnu/local.mk b/gnu/local.mk
index bd8d391b05..08feab3e01 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1044,9 +1044,6 @@ dist_patch_DATA =						\
   %D%/packages/patches/dstat-skip-devices-without-io.patch	\
   %D%/packages/patches/dvd+rw-tools-add-include.patch 		\
   %D%/packages/patches/dynaconf-unvendor-deps.patch		\
-  %D%/packages/patches/ecl-16-format-directive-limit.patch	\
-  %D%/packages/patches/ecl-16-ignore-stderr-write-error.patch	\
-  %D%/packages/patches/ecl-16-libffi.patch			\
   %D%/packages/patches/efibootmgr-remove-extra-decl.patch	\
   %D%/packages/patches/efivar-211.patch			\
   %D%/packages/patches/eigen-fix-strict-aliasing-bug.patch	\
@@ -1387,6 +1384,8 @@ dist_patch_DATA =						\
   %D%/packages/patches/lightdm-vncserver-check.patch		\
   %D%/packages/patches/lightdm-vnc-color-depth.patch		\
   %D%/packages/patches/localed-xorg-keyboard.patch		\
+  %D%/packages/patches/kcontacts-incorrect-country-name.patch	\
+  %D%/packages/patches/kde-cli-tools-delay-mime-db.patch	\
   %D%/packages/patches/kdiagram-Fix-missing-link-libraries.patch \
   %D%/packages/patches/kiki-level-selection-crash.patch		\
   %D%/packages/patches/kiki-makefile.patch			\
@@ -1440,6 +1439,7 @@ dist_patch_DATA =						\
   %D%/packages/patches/libofa-ftbfs-2.diff		\
   %D%/packages/patches/libotr-test-auth-fix.patch		\
   %D%/packages/patches/libksieve-Fix-missing-link-libraries.patch \
+  %D%/packages/patches/libksysguard-qdiriterator-follow-symlinks.patch \
   %D%/packages/patches/libmad-armv7-thumb-pt1.patch		\
   %D%/packages/patches/libmad-armv7-thumb-pt2.patch		\
   %D%/packages/patches/libmad-length-check.patch		\
@@ -1483,7 +1483,8 @@ dist_patch_DATA =						\
   %D%/packages/patches/lierolibre-try-building-other-arch.patch	\
   %D%/packages/patches/libcdio-glibc-compat.patch		\
   %D%/packages/patches/linbox-fix-pkgconfig.patch		\
-  %D%/packages/patches/linphone-desktop-without-sdk.patch           \
+  %D%/packages/patches/linphone-desktop-without-sdk.patch	\
+  %D%/packages/patches/linux-libre-infodocs-target.patch	\
   %D%/packages/patches/linux-libre-support-for-Pinebook-Pro.patch \
   %D%/packages/patches/linux-pam-no-setfsuid.patch		\
   %D%/packages/patches/linuxdcpp-openssl-1.1.patch		\
@@ -1561,6 +1562,7 @@ dist_patch_DATA =						\
   %D%/packages/patches/musl-cross-locale.patch			\
   %D%/packages/patches/mutt-store-references.patch		\
   %D%/packages/patches/m4-gnulib-libio.patch			\
+  %D%/packages/patches/nautilus-extension-search-path.patch	\
   %D%/packages/patches/ncompress-fix-softlinks.patch		\
   %D%/packages/patches/ncftp-reproducible.patch			\
   %D%/packages/patches/netcdf-date-time.patch			\
@@ -1988,6 +1990,8 @@ dist_patch_DATA =						\
   %D%/packages/patches/vtk-7-gcc-10-compat.patch		\
   %D%/packages/patches/vtk-7-hdf5-compat.patch			\
   %D%/packages/patches/vtk-7-python-compat.patch		\
+  %D%/packages/patches/wacomtablet-add-missing-includes.patch	\
+  %D%/packages/patches/wacomtablet-qt5.15.patch			\
   %D%/packages/patches/warsow-qfusion-fix-bool-return-type.patch	\
   %D%/packages/patches/webkitgtk-adjust-bubblewrap-paths.patch	\
   %D%/packages/patches/webrtc-audio-processing-big-endian.patch	\
diff --git a/gnu/packages/astronomy.scm b/gnu/packages/astronomy.scm
index bc31a12594..767b4c4d96 100644
--- a/gnu/packages/astronomy.scm
+++ b/gnu/packages/astronomy.scm
@@ -36,6 +36,7 @@
   #:use-module (gnu packages cmake)
   #:use-module (gnu packages compression)
   #:use-module (gnu packages curl)
+  #:use-module (gnu packages databases)
   #:use-module (gnu packages flex)
   #:use-module (gnu packages fontutils)
   #:use-module (gnu packages gcc)
@@ -58,6 +59,7 @@
   #:use-module (gnu packages python)
   #:use-module (gnu packages python-build)
   #:use-module (gnu packages python-check)
+  #:use-module (gnu packages python-compression)
   #:use-module (gnu packages python-crypto)
   #:use-module (gnu packages python-science)
   #:use-module (gnu packages python-web)
@@ -78,6 +80,7 @@
   #:use-module (guix build-system gnu)
   #:use-module (guix build-system meson)
   #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (guix download)
   #:use-module (guix gexp)
   #:use-module (guix git-download)
@@ -1099,7 +1102,7 @@ to access online Astronomical data.  Each web service has its own sub-package.")
 (define-public python-cdflib
   (package
     (name "python-cdflib")
-    (version "0.4.4")
+    (version "0.4.9")
     (source
      (origin
        (method git-fetch)   ; no tests in pypi archive
@@ -1108,16 +1111,14 @@ to access online Astronomical data.  Each web service has its own sub-package.")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "1h7750xvr6qbhnl2w3bhccs3pwp3hci3624pvvxym0yjinmskjlz"))))
-    (build-system python-build-system)
+        (base32 "1k557najk7ln293zwyghnhw48ays3nqf9s94kibsc7r70c2q7p08"))))
+    (build-system pyproject-build-system)
     (arguments
      (list #:phases
            #~(modify-phases %standard-phases
-               (replace 'check
-                 (lambda* (#:key tests? #:allow-other-keys)
-                   (when tests?
-                     (setenv "HOME" (getcwd))
-                     (invoke "pytest" "-vv" "tests")))))))
+               (add-before 'check 'set-home-env
+                 (lambda _
+                   (setenv "HOME" (getcwd)))))))
     (propagated-inputs
      (list python-attrs python-numpy))
     (native-inputs
@@ -1129,7 +1130,8 @@ to access online Astronomical data.  Each web service has its own sub-package.")
            python-xarray))
     (home-page "https://github.com/MAVENSDC/cdflib")
     (synopsis "Python library to deal with NASA's CDF astronmical data format")
-    (description "This package provides a Python CDF reader toolkit
+    (description "This package provides a Python @acronym{CDF, Computable
+Document Format} reader toolkit.
 It provides the following functionality:
 @itemize
 @item Ability to read variables and attributes from CDF files
@@ -1138,9 +1140,46 @@ It provides the following functionality:
 time formats
 @item Can convert CDF files into XArray Dataset objects and vice versa,
 attempting to maintain ISTP compliance
-@end itemize\n")
+@end itemize")
     (license license:expat)))
 
+(define-public python-drms
+  (package
+    (name "python-drms")
+    (version "0.6.3")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "drms" version))
+       (sha256
+        (base32 "1b0w350y4wbgyy19zcf28xbb85mqq6gnhb6ppibbc4hbn2ixbcvj"))))
+    (build-system python-build-system)
+    (arguments
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (replace 'check
+            (lambda* (#:key inputs outputs tests?
+                      #:allow-other-keys)
+              (when tests?
+                (add-installed-pythonpath inputs outputs)
+                (setenv "JSOC_EMAIL" "jsoc@sunpy.org")
+                (invoke "python" "-m" "pytest" "-vv")))))))
+    (native-inputs
+     (list python-astropy
+           python-pytest-astropy
+           python-pytest
+           python-setuptools-scm))
+    (propagated-inputs (list python-numpy python-pandas))
+    (home-page "https://sunpy.org")
+    (synopsis "Access astronomical HMI, AIA and MDI data with Python")
+    (description
+     "DRMS module provides an easy-to-use interface for accessing HMI, AIA and
+MDI data with Python.  It uses the publicly accessible
+JSOC (@url{http://jsoc.stanford.edu/}) DRMS server by default, but can also be
+used with local NetDRMS sites.")
+    (license license:bsd-2)))
+
 (define-public python-ephem
   (package
     (name "python-ephem")
@@ -1164,6 +1203,53 @@ for a table giving the position of a planet, asteroid, or comet for a series
 of dates.")
     (license license:expat)))
 
+(define-public python-hvpy
+  (package
+    (name "python-hvpy")
+    (version "1.0.1")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "hvpy" version))
+       (sha256
+        (base32 "0r0asyflz2sw9zn5vgs138nh81m0rbwbakmrncbc1ghdr3g6jahv"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list #:tests? #f)) ; Requires HTTP(S) access to api.beta.helioviewer.org
+    (propagated-inputs (list python-pydantic python-requests))
+    (native-inputs (list python-pytest python-pytest-astropy))
+    (home-page "https://helioviewer.org/")
+    (synopsis "Helioviewer Python API Wrapper")
+    (description "@code{hvpy} is a Python API wrapper around the formal
+@url{Helioviewer API, https://api.helioviewer.org/docs/v2/}.")
+    (license license:bsd-2)))
+
+(define-public python-mpl-animators
+  (package
+    (name "python-mpl-animators")
+    (version "1.1.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "mpl_animators" version))
+       (sha256
+        (base32 "12kjmj7rn3pk9ly82h5s5hn0kl3kxkr7bgkz9zr9k59pir8z1r8b"))))
+    (build-system pyproject-build-system)
+    (native-inputs
+     (list python-pytest
+           python-pytest-mpl
+           python-setuptools-scm))
+    (propagated-inputs
+     (list python-astropy
+           python-matplotlib
+           python-numpy))
+    (home-page "https://sunpy.org")
+    (synopsis "Interactive animations with matplotlib")
+    (description
+     "The @code{mpl_animators} package provides a set of classes which allow
+the easy construction of interactive matplotlib widget based animations.")
+    (license license:bsd-3)))
+
 (define-public python-photutils
   (package
     (name "python-photutils")
@@ -1270,6 +1356,146 @@ Virtual observatory (VO) using Python.")
     (description "Regions is an Astropy package for region handling.")
     (license license:bsd-3)))
 
+(define-public python-reproject
+  (package
+    (name "python-reproject")
+    (version "0.9.1")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "reproject" version))
+       (sha256
+        (base32 "1msysqbhkfi3bmw29wipk250a008bnng7din56md9ipbwiar8x55"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      ;; FIXME: Failing tests
+      ;;
+      ;; reproject/adaptive/core.py:7: in <module>
+      ;; from .deforest import map_coordinates
+      ;; E   ModuleNotFoundError: No module named 'reproject.adaptive.deforest'
+      ;;
+      #:tests? #f
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'install 'writable-compiler
+            (lambda _
+              (make-file-writable "reproject/_compiler.c")))
+          (add-before 'check 'writable-compiler
+            (lambda _
+              (make-file-writable "reproject/_compiler.c")))
+          (add-before 'check 'writable-home
+            (lambda _
+              (setenv "HOME" (getcwd)))))))
+    (propagated-inputs
+     (list python-astropy
+           python-astropy-healpix
+           python-numpy
+           python-scipy))
+    (native-inputs
+     (list python-asdf
+           python-cython
+           python-extension-helpers
+           python-gwcs
+           python-pytest-astropy
+           python-pyvo
+           python-semantic-version
+           python-pytest
+           python-setuptools-scm
+           python-shapely))
+    (home-page "https://reproject.readthedocs.io")
+    (synopsis "Astronomical image reprojection in Python")
+    (description
+     "This package provides a functionality to reproject astronomical images using
+various techniques via a uniform interface, where reprojection is the
+re-gridding of images from one world coordinate system to another e.g.
+changing the pixel resolution, orientation, coordinate system.")
+    (license license:bsd-3)))
+
+(define-public python-sunpy
+  (package
+    (name "python-sunpy")
+    (version "4.0.6")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "sunpy" version))
+       (sha256
+        (base32 "0aiirb6l8zshdrpsvh6d5ki759ah9zfm9gbl0in985hprwwxyrq1"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'install 'writable-compiler
+            (lambda _
+              (make-file-writable "sunpy/_compiler.c")))
+          (add-before 'check 'prepare-test-environment
+            (lambda _
+              (setenv "HOME" "/tmp")
+              (make-file-writable "sunpy/_compiler.c")
+              ;; TODO: (Sharlatan-20221106T115800+0000): Review failing tests
+              (substitute* "sunpy/image/tests/test_transform.py"
+                (("def test_clipping") "def __off_test_clipping")
+                (("def test_nans") "def __off_test_nans")
+                (("def test_endian") "def __off_test_endian"))
+              (substitute* "sunpy/map/tests/test_mapbase.py"
+                (("def test_derotating_nonpurerotation_pcij")
+                 "def __off_test_derotating_nonpurerotation_pcij"))
+              (substitute* "sunpy/map/sources/tests/test_mdi_source.py"
+                (("def test_synoptic_source")
+                 "def __off_test_synoptic_source"))
+              (substitute* "sunpy/tests/tests/test_self_test.py"
+                (("def test_main_nonexisting_module")
+                 "def __off_test_main_nonexisting_module")
+                (("def test_main_stdlib_module")
+                 "def __off_test_main_stdlib_module")))))))
+    (native-inputs
+     (list python-aiohttp
+           python-extension-helpers
+           python-hvpy
+           python-packaging
+           python-pytest
+           python-pytest-astropy
+           python-pytest-doctestplus
+           python-pytest-mock
+           python-pytest-mpl
+           python-pytest-xdist
+           python-setuptools-scm))
+    (propagated-inputs
+     (list parfive
+           python-asdf
+           python-asdf-astropy
+           python-astropy
+           python-beautifulsoup4
+           python-cdflib
+           python-dask
+           python-dateutil
+           python-drms
+           python-glymur
+           python-h5netcdf
+           python-h5py
+           python-hypothesis
+           python-jplephem
+           python-matplotlib
+           python-mpl-animators
+           python-numpy
+           ;; python-opencv-python ; not packed yet
+           python-pandas
+           python-reproject
+           python-scikit-image
+           python-scipy
+           python-semantic-version
+           python-sqlalchemy
+           python-tqdm
+           python-zeep))
+    (home-page "https://sunpy.org")
+    (synopsis "Python library for Solar Physics")
+    (description
+     "SunPy is package for solar physics and is meant to be a free alternative to the
+SolarSoft data analysis environment.")
+    (license license:bsd-2)))
+
 (define-public python-astral
   (package
     (name "python-astral")
@@ -1957,26 +2183,40 @@ datetime object.")
 (define-public python-asdf
   (package
     (name "python-asdf")
-    (version "2.8.3")
+    (version "2.13.0")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "asdf" version))
        (sha256
-        (base32 "0i4vq1hsympjgb1yvn4ql0gm8j1mki9ggmj03533kmg0nbzp03yy"))))
-    (build-system python-build-system)
+        (base32 "1zixzv4n2fryaszsfchqh2nvp0gzvarhz03fc721yw6iafdadqij"))))
+    (build-system pyproject-build-system)
     (arguments
-     ;; NOTE: (Sharlatan-20211229T201059+0000): Tests depend on astropy and
-     ;; gwcs, astropy gwcs depend on asdf.  Disable circular dependence.
+     ;; FIXME: Tests fail a lot with
+     ;;
+     ;; ERROR  - _pytest.pathlib.ImportPathMismatchError:
+     ;; ('asdf.conftest', '/gnu/sto...
+     ;;
      `(#:tests? #f))
     (native-inputs
-     (list python-setuptools-scm
+     (list python-astropy
+           python-packaging
+           python-psutil
+           python-pytest
+           python-pytest-doctestplus
+           python-pytest-openfiles
+           python-pytest-remotedata
            python-semantic-version
-           python-packaging))
+           python-setuptools-scm))
     (propagated-inputs
-     (list python-importlib-resources
-           python-jsonschema
+     (list python-asdf-standard
+           python-asdf-transform-schemas
+           python-asdf-unit-schemas
+           python-importlib-metadata
+           python-importlib-resources
            python-jmespath
+           python-jsonschema-next
+           python-lz4
            python-numpy
            python-pyyaml))
     (home-page "https://github.com/asdf-format/asdf")
@@ -1987,31 +2227,63 @@ interchange format for scientific data.  This package contains the Python
 implementation of the ASDF Standard.")
     (license license:bsd-3)))
 
+(define-public python-asdf-standard
+  (package
+    (name "python-asdf-standard")
+    (version "1.0.3")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "asdf_standard" version))
+       (sha256
+        (base32
+         "0i7xdjwn5prg2hcnf1zhw57mszc68jjr5sv4rimpzcg7f2dgzn5g"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (add-before 'check 'remove-blocking-tests
+                          (lambda _
+                            ;; Remove tests require python-asdf where
+                            ;; python-asdf require python-asdf-standard,
+                            ;; break circular dependencies.
+                            (for-each delete-file
+                                      (list "tests/test_manifests.py"
+                                            "tests/test_integration.py")))))))
+    (native-inputs (list python-astropy
+                         python-jsonschema-next
+                         python-pypa-build
+                         python-pytest-7.1
+                         python-packaging
+                         python-setuptools-scm))
+    (propagated-inputs (list python-importlib-resources))
+    (home-page "https://asdf-standard.readthedocs.io/")
+    (synopsis "ASDF standard schemas")
+    (description
+     "This package provides Python implementation of @acronym{ASDF, Advanced
+Scientific Data Format} - a proposed next generation interchange format for
+scientific data.  ASDF aims to exist in the same middle ground that made FITS
+so successful, by being a hybrid text and binary format: containing human
+editable metadata for interchange, and raw binary data that is fast to load
+and use.  Unlike FITS, the metadata is highly structured and is designed
+up-front for extensibility.")
+    (license license:bsd-3)))
+
 (define python-asdf-transform-schemas
   (package
     (name "python-asdf-transform-schemas")
-    (version "0.2.0")
+    (version "0.3.0")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "asdf_transform_schemas" version))
        (sha256
-        (base32 "1gmzd81hw4ppsvzrc91wcbjpcw9hhv9gavllv7nyi7qjb54c837g"))))
-    (build-system python-build-system)
+        (base32 "1midgn575970p5cnsh9y6bz77fjr392b5nfxb3z0id6c49xzzwhc"))))
+    (build-system pyproject-build-system)
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (replace 'check
-           (lambda* (#:key inputs outputs tests? #:allow-other-keys)
-             (when tests?
-               (add-installed-pythonpath inputs outputs)
-               (invoke "python" "-m" "pytest")))))))
-    (native-inputs
-     (list python-pytest
-           python-semantic-version
-           python-setuptools-scm))
-    (propagated-inputs
-     (list python-asdf))
+     ;; Dependency cycle with python-asdf
+     (list #:tests? #f))
+    (native-inputs (list python-setuptools-scm))
+    (propagated-inputs (list python-asdf-standard python-importlib-resources))
     (home-page "https://github.com/asdf-format/asdf-transform-schemas")
     (synopsis "ASDF schemas for transforms")
     (description
@@ -2052,25 +2324,111 @@ coordinates tags.  Users should not need to install this directly; instead,
 install an implementation package such as asdf-astropy.")
     (license license:bsd-3)))
 
+(define python-asdf-fits-schemas
+  ;; TODO: No release, change to tag when it's ready.
+  (let ((commit "572bb370d777f3a325b25c1af9d76e1b7d27dcea")
+        (revision "0"))
+    (package
+      (name "python-asdf-fits-schemas")
+      (version (git-version "0.0.1" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/asdf-format/asdf-fits-schemas")
+               (commit commit)))
+         (file-name (git-file-name name version))
+         (sha256
+          (base32
+           "1yqnzd0gcrdfl0jqm8m8kz5fd36i8lgh7xkglmp1chsi1cc6mkz2"))))
+      (build-system pyproject-build-system)
+      (arguments
+       (list
+        ;; Dependency cycle with python-asdf
+        #:tests? #f
+        #:phases
+        #~(modify-phases %standard-phases
+            (add-before 'build 'set-version
+              (lambda _
+                (setenv "SETUPTOOLS_SCM_PRETEND_VERSION" "0.0.1"))))))
+      (native-inputs (list python-setuptools-scm))
+      (propagated-inputs (list python-asdf-standard python-importlib-resources))
+      (home-page "https://github.com/asdf-format/asdf-fits-schemas")
+      (synopsis "ASDF schemas to support the FITS format")
+      (description
+       "This package provides ASDF schemas for validating FITS tags.")
+      (license license:bsd-3))))
+
+(define python-asdf-time-schemas
+  ;; TODO: No release, change to tag when it's ready.
+  (let ((commit "e9174083d9cfd3c6f7ded9eeb360d99ccb8d9d18")
+        (revision "2"))
+    (package
+      (name "python-asdf-time-schemas")
+      (version (git-version "0.0.1" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/asdf-format/asdf-time-schemas")
+               (commit commit)))
+         (file-name (git-file-name name version))
+         (sha256
+          (base32
+           "1i40hcxp8sds2zq939fwczjlshfqb9r9pnzy3a44c3wqdbwhcbdb"))))
+      (build-system pyproject-build-system)
+      (arguments
+       (list
+        ;; Dependency cycle with python-asdf
+        #:tests? #f
+        #:phases
+        #~(modify-phases %standard-phases
+            (add-before 'build 'set-version
+              (lambda _
+                (setenv "SETUPTOOLS_SCM_PRETEND_VERSION" "0.0.1"))))))
+      (native-inputs (list python-setuptools-scm))
+      (propagated-inputs (list python-asdf-standard
+                               python-asdf-unit-schemas
+                               python-importlib-resources))
+      (home-page "https://github.com/asdf-format/asdf-fits-schemas")
+      (synopsis "Schemas for storing time in ASDF")
+      (description
+       "This package provides ASDF schemas for validating time tags.")
+      (license license:bsd-3))))
+
+(define python-asdf-unit-schemas
+  (package
+    (name "python-asdf-unit-schemas")
+    (version "0.1.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "asdf_unit_schemas" version))
+       (sha256
+        (base32
+         "16grpx3a9h0v1wirp0zqrfsxm867v5c0xyr98pylzziy45kqvds2"))))
+    (build-system pyproject-build-system)
+    (arguments
+     ;; Dependency cycle with python-asdf
+     (list #:tests? #f))
+    (native-inputs (list python-setuptools-scm))
+    (propagated-inputs (list python-asdf-standard python-importlib-resources))
+    (home-page "https://asdf-unit-schemas.readthedocs.io/")
+    (synopsis "ASDF serialization schemas for the units defined by @code{astropy.units}")
+    (description "This package provides ASDF schemas for validating unit tags.")
+    (license license:bsd-3)))
+
 (define-public python-asdf-astropy
   (package
     (name "python-asdf-astropy")
-    (version "0.1.2")
+    (version "0.2.2")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "asdf_astropy" version))
        (sha256
-        (base32 "0bzgah7gskvnz6jcrzipvzixv8k2jzjkskqwxngzwp4nxgjbcvi4"))))
-    (build-system python-build-system)
-    (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (replace 'check
-           (lambda* (#:key inputs outputs tests? #:allow-other-keys)
-             (when tests?
-               (add-installed-pythonpath inputs outputs)
-               (invoke "python" "-m" "pytest")))))))
+        (base32 "1b0v4cl7xvly3x1k5k2rvc2l32jqgqp0iyf1j20fkvj450sx74f2"))))
+    (build-system pyproject-build-system)
     (native-inputs
      (list python-coverage
            python-h5py
@@ -2130,24 +2488,16 @@ install an implementation package such as gwcs.")
 (define-public python-gwcs
   (package
     (name "python-gwcs")
-    (version "0.18.0")
+    (version "0.18.2")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "gwcs" version))
        (sha256
-        (base32 "194j49m8xjjzv9pp8cnj06igz8sdxb0nphyybcc7mhigw0f0kr30"))))
-    (build-system python-build-system)
-    (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (replace 'check
-           (lambda* (#:key inputs outputs tests? #:allow-other-keys)
-             (when tests?
-               (add-installed-pythonpath inputs outputs)
-               (invoke "python" "-m" "pytest")))))))
+        (base32 "0v9qcq6zl74d6s882s6xmas144jfalvll6va8rvrxmvpx4vqjzhg"))))
+    (build-system pyproject-build-system)
     (native-inputs
-     (list python-jsonschema
+     (list python-jsonschema-next
            python-jmespath
            python-pytest
            python-pytest-doctestplus
diff --git a/gnu/packages/audio.scm b/gnu/packages/audio.scm
index a131021fa4..64f5d306f6 100644
--- a/gnu/packages/audio.scm
+++ b/gnu/packages/audio.scm
@@ -3707,7 +3707,8 @@ analysis plugins or audio feature extraction plugins.")
             (symlink
              (search-input-file inputs
                                 (string-append "/share/automake-"
-                                               ,(package-version automake)
+                                               ,(version-major+minor
+                                                 (package-version automake))
                                                "/ar-lib"))
              "ar-lib")
             #t)))))
diff --git a/gnu/packages/backup.scm b/gnu/packages/backup.scm
index fd17992ab3..67708138a6 100644
--- a/gnu/packages/backup.scm
+++ b/gnu/packages/backup.scm
@@ -1036,7 +1036,7 @@ precious backup space.
     (arguments
      `(#:tests? #f))                    ;no test
     (inputs
-     (list lzo libressl protobuf xz zlib))
+     (list lzo libressl protobuf-3.6 xz zlib))
     (home-page "http://zbackup.org")
     (synopsis "Versatile deduplicating backup tool")
     (description
diff --git a/gnu/packages/base.scm b/gnu/packages/base.scm
index bf6435585e..36b27a4e25 100644
--- a/gnu/packages/base.scm
+++ b/gnu/packages/base.scm
@@ -130,7 +130,19 @@ command-line arguments, multiple languages, and so on.")
               (substitute* (list (string-append bin "/egrep")
                                  (string-append bin "/fgrep"))
                 (("^exec grep")
-                 (string-append "exec " bin "/grep")))))))
+                 (string-append "exec " bin "/grep"))))))
+        ,@(if (hurd-target?)
+              '((add-before 'check 'skip-triple-backref-test
+                  (lambda _
+                    ;; This test is marked as malfunctioning on glibc systems
+                    ;; due to
+                    ;; <https://sourceware.org/bugzilla/show_bug.cgi?id=11053>
+                    ;; and it triggers a segfault with glibc 2.33 on GNU/Hurd.
+                    ;; Skip it.
+                    (substitute* "tests/triple-backref"
+                      (("^warn_" all)
+                       (string-append "exit 77\n" all))))))
+              '()))
       #:make-flags ,(if (hurd-target?)
                         ''("XFAIL_TESTS=test-perror2 equiv-classes") ;XXX
                         ''())))
diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index f3b67fd2bf..bb319a13e5 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -506,6 +506,31 @@ ID and species.  It is used by functions in the GenomeInfoDb package.")
 information about the latest version of the Gene Ontologies.")
     (license license:artistic2.0)))
 
+(define-public r-hdo-db
+  (package
+    (name "r-hdo-db")
+    (version "0.99.1")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "HDO.db" version 'annotation))
+              (sha256
+               (base32
+                "14ngyxailmxrbxqqi9m7mchqcvchmbg7zm34i8a927b20s6z4z61"))))
+    (properties `((upstream-name . "HDO.db")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-annotationdbi))
+    (native-inputs
+     (list r-knitr))
+    (home-page "https://bioconductor.org/packages/HDO.db")
+    (synopsis "Annotation maps describing the entire Human Disease Ontology")
+    (description
+     "This package provides a set of annotation maps describing the entire
+Human Disease Ontology.  The annotation data comes from
+@url{Humam Disease Ontology repository,
+https://github.com/DiseaseOntology/HumanDiseaseOntology/tree/main/src/ontology}.")
+    (license license:artistic2.0)))
+
 (define-public r-homo-sapiens
   (package
     (name "r-homo-sapiens")
@@ -1659,13 +1684,13 @@ and @code{Sailfish}.  Alevin example output is also included.")
 (define-public r-abarray
   (package
     (name "r-abarray")
-    (version "1.64.0")
+    (version "1.66.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ABarray" version))
               (sha256
                (base32
-                "0kjq00i2mb21xyjjs3jy09ps80f11cy37wywzjvmxyjxzbsk4d7r"))))
+                "02rjxzbrzphl28z8zpgw3gavzlzlx71n5ld8sb3im6xpn81ykvfh"))))
     (properties `((upstream-name . "ABarray")))
     (build-system r-build-system)
     (propagated-inputs (list r-biobase r-multtest))
@@ -1685,13 +1710,13 @@ into folders according to the analysis settings used.")
 (define-public r-absseq
   (package
     (name "r-absseq")
-    (version "1.50.0")
+    (version "1.52.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ABSSeq" version))
               (sha256
                (base32
-                "1kwl0gcqwbgblwvpbvqlgnsi91km77j11f0q1f0gd6hhnv38mmlv"))))
+                "1ypd0wg3k2zzl0zf15c16dc38hfpsm5vv4x0x0yf90x0f8b6jpaz"))))
     (properties `((upstream-name . "ABSSeq")))
     (build-system r-build-system)
     (propagated-inputs (list r-limma r-locfit))
@@ -1714,13 +1739,13 @@ ranking by fold-change and visualization.")
 (define-public r-adam
   (package
     (name "r-adam")
-    (version "1.12.0")
+    (version "1.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ADAM" version))
               (sha256
                (base32
-                "1cgcjykik9hjrwlvvgaccprcrimgq5kwh9cj6367yk9m574a4gmn"))))
+                "1s1mzjxqld8gllfh6z9kg30klb4y1jrkrif7vwr18c0mhamf47a6"))))
     (properties `((upstream-name . "ADAM")))
     (build-system r-build-system)
     (propagated-inputs (list r-dplyr
@@ -1749,13 +1774,13 @@ functionally associated genes} (GFAG).")
 (define-public r-adamgui
   (package
     (name "r-adamgui")
-    (version "1.12.0")
+    (version "1.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ADAMgui" version))
               (sha256
                (base32
-                "0vvd5qdwkfcr7zg7z63x3vvrcg63r6c9p383yvcg2lp8zmx8hsbs"))))
+                "1ks799kgdmlxn5iyj6rzj04cm28klivclz3bg6bc4wad2q7h4ra9"))))
     (properties `((upstream-name . "ADAMgui")))
     (build-system r-build-system)
     (propagated-inputs
@@ -1797,13 +1822,13 @@ the @code{GFAGpathUi} function.")
 (define-public r-adimpute
   (package
     (name "r-adimpute")
-    (version "1.6.0")
+    (version "1.8.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ADImpute" version))
               (sha256
                (base32
-                "0885kd8mpmwjpzpx14pi6l3mqcvsixk10vkf5h4sqb7di0nnna4w"))))
+                "0wrprxd91vi4wwh9wixhx1ppbjsb56r4kcxgqz8w6ahr3z2387im"))))
     (properties `((upstream-name . "ADImpute")))
     (build-system r-build-system)
     (propagated-inputs
@@ -1846,13 +1871,13 @@ results from different methods into an ensemble.")
 (define-public r-adsplit
   (package
     (name "r-adsplit")
-    (version "1.66.0")
+    (version "1.68.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "adSplit" version))
               (sha256
                (base32
-                "1wl2gd0b7krf485clw67cxayp0g9argklkzn8nw1vrkil0vvr4jm"))))
+                "0a05j1g42wnw5lcn6g6vp2z3mnjz185b2hvdg362ln270r19gch6"))))
     (properties `((upstream-name . "adSplit")))
     (build-system r-build-system)
     (propagated-inputs
@@ -1874,13 +1899,13 @@ the supporting gene set is determined.")
 (define-public r-affixcan
   (package
     (name "r-affixcan")
-    (version "1.14.0")
+    (version "1.16.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AffiXcan" version))
               (sha256
                (base32
-                "0wj9shzmlxpksbxny571xzfcmmqqzjlk1vq4mx1is2r6ma7jkblq"))))
+                "1jsdl477qhsq3rpqvgdm7navr4izpppfkiw0fvlhxwspgp3fjs6c"))))
     (properties `((upstream-name . "AffiXcan")))
     (build-system r-build-system)
     (propagated-inputs
@@ -1902,13 +1927,13 @@ expression values are known.")
 (define-public r-affyrnadegradation
   (package
     (name "r-affyrnadegradation")
-    (version "1.42.0")
+    (version "1.44.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AffyRNADegradation" version))
               (sha256
                (base32
-                "16akwmpzwxai7ks5bvc1yyb9sx2scv9b9gas5avb0sk5fk0h3nsf"))))
+                "1n6x2c0h6xmcll7mxq4n1y8ahqfmba8ppdcrjk9hf3nh5wngprkz"))))
     (properties `((upstream-name . "AffyRNADegradation")))
     (build-system r-build-system)
     (propagated-inputs (list r-affy))
@@ -1927,13 +1952,13 @@ of samples that are affected by RNA degradation.")
 (define-public r-agdex
   (package
     (name "r-agdex")
-    (version "1.44.0")
+    (version "1.46.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AGDEX" version))
               (sha256
                (base32
-                "0c44fw5ajdjc13409rn3lsv0jhlqa2qcak9b1k8hpig486xxzsr9"))))
+                "0yvdx32yr4mv7dl5ycpbxhrkm6csrr7k3398ggjavdcfhz54dgr8"))))
     (properties `((upstream-name . "AGDEX")))
     (build-system r-build-system)
     (propagated-inputs (list r-biobase r-gseabase))
@@ -1954,13 +1979,13 @@ experiment.")
 (define-public r-aggregatebiovar
   (package
     (name "r-aggregatebiovar")
-    (version "1.6.0")
+    (version "1.8.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "aggregateBioVar" version))
               (sha256
                (base32
-                "0ngg12bgr95m4wm12scmrb55dgy4909c6qrg169l6dkng99v4nx1"))))
+                "1snsc2430cc7cd0k01n1rwa6vympd79g1mcch0paxxkq7msvfn42"))))
     (properties `((upstream-name . "aggregateBioVar")))
     (build-system r-build-system)
     (propagated-inputs
@@ -1988,13 +2013,13 @@ bulk RNA-seq tools.")
 (define-public r-agilp
   (package
     (name "r-agilp")
-    (version "3.28.0")
+    (version "3.30.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "agilp" version))
               (sha256
                (base32
-                "1pm329y2nfcnx98ggxq0prdd5pxfcl5iylvsjjnhw5lyz1awg1yf"))))
+                "15cw004g1vxfwvf939018vmlv9gym4r473jissamkygqdv78hcr0"))))
     (properties `((upstream-name . "agilp")))
     (build-system r-build-system)
     (home-page "https://bioconductor.org/packages/agilp")
@@ -2010,13 +2035,13 @@ but which also provides utilities which may be useful for other platforms.")
 (define-public r-adductomicsr
   (package
     (name "r-adductomicsr")
-    (version "1.12.0")
+    (version "1.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "adductomicsR" version))
               (sha256
                (base32
-                "0623qf06xgdsyz0in2wnxwvpdw8kj6cnwf8vlqmgp7g0n3w701ys"))))
+                "0h180k4r1lrij1smpibbqgiki1hb2q87n5ay6habig4bxzbx773x"))))
     (properties `((upstream-name . "adductomicsR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2055,13 +2080,13 @@ mass spectrometry} (MS1) data.")
 (define-public r-agimicrorna
   (package
     (name "r-agimicrorna")
-    (version "2.46.0")
+    (version "2.48.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AgiMicroRna" version))
               (sha256
                (base32
-                "0jic89gyphbv7jzlfgm9bh1aq48lp86rq6hr34gsg9z0pa1192xa"))))
+                "0q3hynyd4dhhh1a2b27y3rrshgvxfwv17k7yabh6g4pc12c33mf7"))))
     (properties `((upstream-name . "AgiMicroRna")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2082,16 +2107,40 @@ using the linear model features implemented in limma.  Standard Bioconductor
 objects are used so that other packages could be used as well.")
     (license license:gpl3)))
 
+(define-public r-aims
+  (package
+    (name "r-aims")
+    (version "1.30.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "AIMS" version))
+              (sha256
+               (base32
+                "1civ4a14ynccv6xs27fm95fw6254l1z0q37546ivyv2mhbz0d2i1"))))
+    (properties `((upstream-name . "AIMS")))
+    (build-system r-build-system)
+    (propagated-inputs (list r-biobase r-e1071))
+    (home-page "https://git.bioconductor.org/packages/AIMS")
+    (synopsis
+     "Absolute assignment of breast cancer intrinsic molecular subtype")
+    (description
+     "This package contains an implementation of @code{AIMS} -- Absolute
+Intrinsic Molecular Subtyping.  It contains necessary functions to assign the
+five intrinsic molecular subtypes (Luminal A, Luminal B, Her2-enriched,
+Basal-like, Normal-like).  Assignments could be done on individual samples as
+well as on dataset of gene expression data.")
+    (license license:artistic2.0)))
+
 (define-public r-airpart
   (package
     (name "r-airpart")
-    (version "1.4.0")
+    (version "1.6.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "airpart" version))
               (sha256
                (base32
-                "0ljankgvgf8rby4z340wxx8v7acs9yz955p3a40jl6y8rz1svc06"))))
+                "07zxv0sjhlajaw4gxpjni14qyyqn70ar8ph5cpibzcky1lx6pmkl"))))
     (properties `((upstream-name . "airpart")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2132,13 +2181,13 @@ datasets.")
 (define-public r-amountain
   (package
     (name "r-amountain")
-    (version "1.22.0")
+    (version "1.24.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AMOUNTAIN" version))
               (sha256
                (base32
-                "0vdfabsrisdd7qq28f5ivd0v8zz49szqn677i5lhwnlaix220c54"))))
+                "0zzl5dv64yhdivsm2pgsfjikygib9pkfiv34h1lnmqrj6yivvvw8"))))
     (properties `((upstream-name . "AMOUNTAIN")))
     (build-system r-build-system)
     (inputs (list gsl))
@@ -2156,13 +2205,13 @@ in multi-layer WGCN using a continuous optimization approach.")
 (define-public r-amaretto
   (package
     (name "r-amaretto")
-    (version "1.12.0")
+    (version "1.13.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AMARETTO" version))
               (sha256
                (base32
-                "111dk19b9910icksyr592cvhc5gwvgknr5q4887j9yxbajd7hcmx"))))
+                "18w65sf3h4yzw9v5xgkalxnkmgzgsx100v7qc7z4ifx10lgpji5n"))))
     (properties `((upstream-name . "AMARETTO")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2208,13 +2257,13 @@ canonical cancer pathways.")
 (define-public r-anaquin
   (package
     (name "r-anaquin")
-    (version "2.20.0")
+    (version "2.22.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "Anaquin" version))
               (sha256
                (base32
-                "1jgpnls2djl1yzvnk64qc83mljmlci7wflwkza3wr0sv6r47b0dd"))))
+                "08y2syaacy15rxcf3x2r3906kfm58fkx7ainaqvy5inlc9f670j5"))))
     (properties `((upstream-name . "Anaquin")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2235,16 +2284,69 @@ of Medical Research.  The goal is to provide a standard library for quantitative
 analysis, modelling, and visualization of spike-in controls.")
     (license license:bsd-3)))
 
+(define-public r-ancombc
+  (package
+    (name "r-ancombc")
+    (version "2.0.1")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "ANCOMBC" version))
+              (sha256
+               (base32
+                "1bwzvi6j3s66dcll1lb4xy25j4nfn1ln6mc3flh0wgy13l26x8m6"))))
+    (properties `((upstream-name . "ANCOMBC")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-cvxr
+           r-desctools
+           r-doparallel
+           r-dorng
+           r-dplyr
+           r-emmeans
+           r-energy
+           r-foreach
+           r-hmisc
+           r-lme4
+           r-lmertest
+           r-magrittr
+           r-mass
+           r-mia
+           r-nloptr
+           r-rdpack
+           r-rlang
+           r-rngtools
+           r-s4vectors
+           r-singlecellexperiment
+           r-summarizedexperiment
+           r-tibble
+           r-tidyr
+           r-treesummarizedexperiment))
+    (native-inputs (list r-knitr))
+    (home-page "https://github.com/FrederickHuangLin/ANCOMBC")
+    (synopsis "Analysis of compositions of microbiomes with bias correction")
+    (description
+     "@code{ANCOMBC} is a package containing @dfn{differential abundance} (DA)
+and correlation analyses for microbiome data.  Specifically, the package
+includes @dfn{Analysis of Compositions of Microbiomes with Bias
+Correction}(ANCOM-BC) and @dfn{Analysis of Composition of Microbiomes} (ANCOM)
+for DA analysis, and @dfn{Sparse Estimation of Correlations among
+Microbiomes} (SECOM) for correlation analysis.  Microbiome data are typically
+subject to two sources of biases: unequal sampling fractions (sample-specific
+biases) and differential sequencing efficiencies (taxon-specific biases).
+Methodologies included in the @code{ANCOMBC} package were designed to correct
+these biases and construct statistically consistent estimators.")
+    (license license:artistic2.0)))
+
 (define-public r-aldex2
   (package
     (name "r-aldex2")
-    (version "1.28.1")
+    (version "1.30.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ALDEx2" version))
               (sha256
                (base32
-                "0xppx52sllbz4pli174422i4kkf37v0yl844088nbj3j9r6pfbj9"))))
+                "0585s5pb8zr9il1vhxw9vjzzajmdcjmf9zz3zlc5vpczd3fnzfkf"))))
     (properties `((upstream-name . "ALDEx2")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2276,16 +2378,130 @@ paired or unpaired study designs.")
     ;; package's LICENSE is specified as GPL-3.
     (license (list license:agpl3+ license:gpl2+ license:gpl3))))
 
+(define-public r-alevinqc
+  (package
+    (name "r-alevinqc")
+    (version "1.14.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "alevinQC" version))
+              (sha256
+               (base32
+                "0rd64j4hkdk2d6mlld6qkv2m96lqc93807xjdf05xm8qkyx8g8y2"))))
+    (properties `((upstream-name . "alevinQC")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-cowplot
+           r-dplyr
+           r-dt
+           r-ggally
+           r-ggplot2
+           r-rcpp
+           r-rjson
+           r-rlang
+           r-rmarkdown
+           r-shiny
+           r-shinydashboard
+           r-tximport))
+    (native-inputs (list r-knitr))
+    (home-page "https://github.com/csoneson/alevinQC")
+    (synopsis "Quality control reports for @code{Alevin} output")
+    (description
+     "The package @code{r-alevinqc} generates quality control reports
+summarizing the output from an @code{alevin} run.  The reports can be
+generated as HTML or PDF files, or as Shiny applications.")
+    (license license:expat)))
+
+(define-public r-alphabeta
+  (package
+    (name "r-alphabeta")
+    (version "1.12.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "AlphaBeta" version))
+              (sha256
+               (base32
+                "000apg879li9wkbyrl8cm73z6h0xasqp41h9ir9hywy2v38rmc5b"))))
+    (properties `((upstream-name . "AlphaBeta")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-biocparallel
+           r-data-table
+           r-dplyr
+           r-expm
+           r-ggplot2
+           r-gtools
+           r-igraph
+           r-optimx
+           r-plotly
+           r-stringr))
+    (native-inputs (list r-knitr))
+    (home-page "https://bioconductor.org/packages/AlphaBeta")
+    (synopsis "Estimate epimutation rates and spectra from DNA methylations in plants")
+    (description
+     "The package @code{AlphaBeta} is a computational method for estimating
+epimutation rates and spectra from high-throughput DNA methylation data in
+plants.  The method has been specifically designed to:
+
+@itemize
+@item analyze @emph{germline} epimutations in the context of
+  multi-generational mutation accumulation lines;
+@item analyze @emph{somatic} epimutations in the context of plant development
+  and aging.
+@end itemize")
+    (license license:gpl3)))
+
+(define-public r-alpine
+  (package
+    (name "r-alpine")
+    (version "1.22.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "alpine" version))
+              (sha256
+               (base32
+                "1nl1hxwakh5m9rqm3ksn2jzknsj9xnwl51bmc30knknm4q35wdv9"))))
+    (properties `((upstream-name . "alpine")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-biostrings
+           r-genomeinfodb
+           r-genomicalignments
+           r-genomicfeatures
+           r-genomicranges
+           r-graph
+           r-iranges
+           r-rbgl
+           r-rsamtools
+           r-s4vectors
+           r-speedglm
+           r-stringr
+           r-summarizedexperiment))
+    (native-inputs (list r-knitr))
+    (home-page "https://bioconductor.org/packages/alpine")
+    (synopsis "Modeling and correcting fragment sequence bias")
+    (description
+     "The package @code{alpine} helps to model bias parameters and then using
+those parameters to estimate RNA-seq transcript abundance.  @code{Alpine} is a
+package for estimating and visualizing many forms of sample-specific biases that
+can arise in RNA-seq, including fragment length distribution, positional bias on
+the transcript, read start bias (random hexamer priming), and fragment GC-content
+(amplification).  It also offers bias-corrected estimates of transcript
+abundance in @dfn{FPKM}(Fragments Per Kilobase of transcript per Million
+mapped reads).  It is currently designed for un-stranded paired-end RNA-seq
+data.")
+    (license license:gpl2+)))
+
 (define-public r-aneufinder
   (package
     (name "r-aneufinder")
-    (version "1.24.0")
+    (version "1.26.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AneuFinder" version))
               (sha256
                (base32
-                "1acsp987jv2x4qwbgy3y7ff4r2qz7680b0nbr37m4lmncqfgh8yl"))))
+                "154cg63n7h9h5jkj00aqf0hzbmmjg16bzvvk50fyixwq0a4q1j00"))))
     (build-system r-build-system)
     (native-inputs
      (list r-knitr))
@@ -2321,13 +2537,13 @@ sequencing data.")
 (define-public r-anf
   (package
     (name "r-anf")
-    (version "1.18.0")
+    (version "1.20.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ANF" version))
               (sha256
                (base32
-                "1fa2pbdapymrpz01ws0m2fbzf11d723x6rbsys29v06is57f5lpj"))))
+                "0yfwvgx7144r894fr13sx4gyyq6ljh7y734wx74sb7q80cl2gs1j"))))
     (properties `((upstream-name . "ANF")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2349,13 +2565,13 @@ network fusion.")
 (define-public r-annmap
   (package
     (name "r-annmap")
-    (version "1.38.0")
+    (version "1.40.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "annmap" version))
               (sha256
                (base32
-                "0ywqbb8jia7rrkzcsf6a11kqf8dnx96z8n8xw7067mahycykbixv"))))
+                "18ia189qgsbcivpfsfss05dnd3kdc6gmswq8i1whwf9n227b2cv3"))))
     (properties `((upstream-name . "annmap")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2383,13 +2599,13 @@ Functions to plot gene architecture and BAM file data are also provided.")
 (define-public r-antiprofiles
   (package
     (name "r-antiprofiles")
-    (version "1.36.0")
+    (version "1.38.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "antiProfiles" version))
               (sha256
                (base32
-                "1277kg5xpyb2yriyjy18p437q5lj22h4al7z7pygkzxzywxv9g40"))))
+                "0f32373ncfjbvy05yngmfhhdgyc99a4idz3ry2xlabdmrbs5yac3"))))
     (properties `((upstream-name . "antiProfiles")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2406,16 +2622,64 @@ reproducible gene expression signatures capable of accurately distinguishing
 tumor samples from healthy controls.")
     (license license:artistic2.0)))
 
+(define-public r-arrayexpress
+  (package
+    (name "r-arrayexpress")
+    (version "1.57.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "ArrayExpress" version))
+              (sha256
+               (base32
+                "1fzi951mjc4kbkkvlfvwlfrpfnjckkmw4xz4m5dapy1z2jkgp8w6"))))
+    (properties `((upstream-name . "ArrayExpress")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-biobase
+           r-limma
+           r-oligo
+           r-xml))
+    (home-page "https://bioconductor.org/packages/ArrayExpress")
+    (synopsis "Building R objects from ArrayExpress datasets")
+    (description
+     "This package offers the possibility to access the ArrayExpress repository
+at @dfn{EBI} (European Bioinformatics Institute) and build Bioconductor data
+structures: @code{ExpressionSet}, @code{AffyBatch}, @code{NChannelSet}.")
+    (license license:artistic2.0)))
+
+(define-public r-asafe
+  (package
+    (name "r-asafe")
+    (version "1.24.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "ASAFE" version))
+              (sha256
+               (base32
+                "1q4i33rw1qb8bnvkl06izl4nyl9lzgwy8rwrmvbrz1c384pmy8yj"))))
+    (properties `((upstream-name . "ASAFE")))
+    (build-system r-build-system)
+    (native-inputs (list r-knitr))
+    (home-page "https://bioconductor.org/packages/ASAFE")
+    (synopsis "Ancestry Specific Allele Frequency Estimation")
+    (description
+     "The @code{ASAFE} package contains a collection of functions that can be
+used to carry out an @dfn{EM} (Expectation–maximization) algorithm to estimate
+ancestry-specific allele frequencies for a bi-allelic genetic marker, e.g. an
+@dfn{SNP} (single nucleotide polymorphism) from genotypes and ancestry
+pairs.")
+    (license license:artistic2.0)))
+
 (define-public r-aseb
   (package
     (name "r-aseb")
-    (version "1.40.0")
+    (version "1.42.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ASEB" version))
               (sha256
                (base32
-                "1i0r4vimk6is4j4rr14ajp8papznpmmr0bhwd96s8w53cqdqph7p"))))
+                "1kr6l2ma7wzy8i9dn86zx927yvx1l4bnkxhv97ra3sh5vr6m8ywa"))))
     (properties `((upstream-name . "ASEB")))
     (build-system r-build-system)
     (home-page "https://bioconductor.org/packages/ASEB")
@@ -2436,13 +2700,13 @@ RNAs.")
 (define-public r-asgsca
   (package
     (name "r-asgsca")
-    (version "1.30.0")
+    (version "1.32.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ASGSCA" version))
               (sha256
                (base32
-                "0mxrrkm2lg7gxjh8ynn6qmryn8wqda7b83sr51dpgblay83jcbaq"))))
+                "12wap8xbq6xl7p430yd9yy5kdhs15n7nmv2h3k9bsi0f4m6md02i"))))
     (properties `((upstream-name . "ASGSCA")))
     (build-system r-build-system)
     (propagated-inputs (list r-mass r-matrix))
@@ -2459,13 +2723,13 @@ model as latent variables.")
 (define-public r-aspli
   (package
     (name "r-aspli")
-    (version "2.6.0")
+    (version "2.8.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ASpli" version))
               (sha256
                (base32
-                "1frlcwa8m4imfx6ncav8r8yskyaf4ibha177mfnp9y84w6mphynz"))))
+                "0gwp5ijpxjy6hd1090cmwbfrfac1qqrzxc06n1j89c0va7wm9l4k"))))
     (properties `((upstream-name . "ASpli")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2507,13 +2771,13 @@ that might arise in splicing patterns.")
 (define-public r-assessorf
   (package
     (name "r-assessorf")
-    (version "1.14.0")
+    (version "1.16.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AssessORF" version))
               (sha256
                (base32
-                "1l87bpny9k3jbzbzmb9h2ijvblrj471gqv26fyzbvb3vr6y406z7"))))
+                "125qkjsjyxp6zk3nzfamakyfgm7wd7w9vv1vn7xyyylpqpa8rpml"))))
     (properties `((upstream-name . "AssessORF")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2536,13 +2800,13 @@ start codons as the forms of evidence.")
 (define-public r-asset
   (package
     (name "r-asset")
-    (version "2.14.0")
+    (version "2.16.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ASSET" version))
               (sha256
                (base32
-                "029acl5k9d4hnvy3jia9cr4rk6w31zn8b5s79i6lazq1cp236hbg"))))
+                "13zwnjap4y0s3qqv10mv2i4mqan9nmkm2l29i448h1j3wwfq18j2"))))
     (properties `((upstream-name . "ASSET")))
     (build-system r-build-system)
     (propagated-inputs (list r-mass r-msm r-rmeta))
@@ -2563,13 +2827,13 @@ variant.")
 (define-public r-atena
   (package
     (name "r-atena")
-    (version "1.2.2")
+    (version "1.4.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "atena" version))
               (sha256
                (base32
-                "0b89wb7cc44c8jd6868dn8pwgid768bprkncsi87qkdz0abbhzhp"))))
+                "1a3qv66caz2pg67ff9c5424pygsgqnfx67ybzc3zkzaw4fj8cp54"))))
     (properties `((upstream-name . "atena")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2604,13 +2868,13 @@ transcripts in an integrated manner.")
 (define-public r-atsnp
   (package
     (name "r-atsnp")
-    (version "1.12.0")
+    (version "1.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "atSNP" version))
               (sha256
                (base32
-                "0dmv34xqwr3l2rznapxmyrkyf1w78qzxdv88s5nn8s1m8qdkgwkz"))))
+                "12za1agpbjjg4i94mikbkdbwqnkzzwz07v0gwdc7lpa9899q2ycb"))))
     (properties `((upstream-name . "atSNP")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2637,13 +2901,13 @@ SNP-led changes in motif matches.")
 (define-public r-attract
   (package
     (name "r-attract")
-    (version "1.48.0")
+    (version "1.50.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "attract" version))
               (sha256
                (base32
-                "0f1fsv278kpnxvqg9qa5rw2k3zr8zws0ab73ldl60h6pv9cy8x82"))))
+                "0r5vykjqq33gchqv0wp2i6wpnk95cv26w5j4yqxcnw0bnqfhrgkm"))))
     (properties `((upstream-name . "attract")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2668,13 +2932,13 @@ transcriptionally-coordinated changes in gene expression.")
 (define-public r-awfisher
   (package
     (name "r-awfisher")
-    (version "1.10.0")
+    (version "1.12.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AWFisher" version))
               (sha256
                (base32
-                "050k7w0azsl7rqx2pxgccihzc2q8pmh6fyy4gib2d42sdyijr2n1"))))
+                "1psbxxrwb6mk2jwjw963vwdczb3i5590rcm7hk43kpiw45i1q1j9"))))
     (properties `((upstream-name . "AWFisher")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2692,13 +2956,13 @@ meta-pattern.")
 (define-public r-awst
   (package
     (name "r-awst")
-    (version "1.4.0")
+    (version "1.6.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "awst" version))
               (sha256
                (base32
-                "0iw3zycmj95rmdx7f2w0j4yxkzd90y87lrzgdn9cyvvzi5avflav"))))
+                "0dvzkqpjv7whns9q8zj6n2nyvnaw2ib7i53vf049n94x52vh9x15"))))
     (properties `((upstream-name . "awst")))
     (build-system r-build-system)
     (propagated-inputs (list r-summarizedexperiment))
@@ -2719,13 +2983,13 @@ artifacts.")
 (define-public r-baalchip
   (package
     (name "r-baalchip")
-    (version "1.22.0")
+    (version "1.24.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BaalChIP" version))
               (sha256
                (base32
-                "02qwk9n2fyg5f9xxjiiha9mi6p9ii3zi5x7w84sh5d5g58s27g6q"))))
+                "16s67v6mkv14dkk1r7c50brm7198b84h87h1wrahmrrcnzq8pi0n"))))
     (properties `((upstream-name . "BaalChIP")))
     (build-system r-build-system)
     (inputs (list perl)) ; extra/get.overlaps.v2_chrXY.perl
@@ -2759,13 +3023,13 @@ alleles, a known phenotypical feature of cancer samples.")
 (define-public r-basespacer
   (package
     (name "r-basespacer")
-    (version "1.40.0")
+    (version "1.42.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BaseSpaceR" version))
               (sha256
                (base32
-                "0jyw4pnybsd6ywpaamk5ywkrcib2z48farsnszmwq97zlbmra7fj"))))
+                "07pqs0jkwcbxavc65sanvhvzc9spkk46bqnwz162f3pvrz15b5h7"))))
     (properties `((upstream-name . "BaseSpaceR")))
     (build-system r-build-system)
     (propagated-inputs (list r-rcurl r-rjsonio))
@@ -2782,13 +3046,13 @@ rich environment of statistical and data analysis tools.")
 (define-public r-bac
   (package
     (name "r-bac")
-    (version "1.56.0")
+    (version "1.58.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BAC" version))
               (sha256
                (base32
-                "0dkw7438d2sf6nb577dnzija54qs0nhlr47lb73li60fhlnvqmh2"))))
+                "00dkhns9n1x4wmlxjcw75h7iwwk37zlv1c2fi0g1mmsw1xvdjzp6"))))
     (properties `((upstream-name . "BAC")))
     (build-system r-build-system)
     (home-page "https://bioconductor.org/packages/BAC")
@@ -2806,13 +3070,13 @@ you will have to normalize your data beforehand.")
 (define-public r-bader
   (package
     (name "r-bader")
-    (version "1.34.0")
+    (version "1.36.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BADER" version))
               (sha256
                (base32
-                "0i5x1r2ns1hxhqk5jyfqird81hck1hllvvgx5bn0rb5vl99g8spm"))))
+                "1hkvmfik4m2yw5xg4k2g551l27i64blbsdvp1kmvvyix66p53hsr"))))
     (properties `((upstream-name . "BADER")))
     (build-system r-build-system)
     (home-page "https://bioconductor.org/packages/BADER")
@@ -2830,13 +3094,13 @@ can be used for further down-stream analyses such as gene set enrichment.")
 (define-public r-badregionfinder
   (package
     (name "r-badregionfinder")
-    (version "1.24.0")
+    (version "1.26.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BadRegionFinder" version))
               (sha256
                (base32
-                "1a1pqmh5ak9s3k1lxw6flanchk24zyznwm34ixi2b78wdc3hqgm9"))))
+                "0bsgdjchwsfc8aiwiacr454kw97dbymq6v450m1fx7hxmmpqz1sm"))))
     (properties `((upstream-name . "BadRegionFinder")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2857,13 +3121,13 @@ Various visual and textual types of output are available.")
 (define-public r-bambu
   (package
     (name "r-bambu")
-    (version "2.2.0")
+    (version "3.0.2")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "bambu" version))
               (sha256
                (base32
-                "0dc2hpnykr575jbrq9whmdabknl70s2hcs6gkmkl4kpv7xfqdq6w"))))
+                "0246cn5l1kxysjrzy4prfdxn71vc47a8kciqw384nm2mi3vsy4vx"))))
     (properties `((upstream-name . "bambu")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2900,13 +3164,13 @@ usage.")
 (define-public r-bandits
   (package
     (name "r-bandits")
-    (version "1.12.0")
+    (version "1.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BANDITS" version))
               (sha256
                (base32
-                "1423djb7cij68y0q2dcp8q7lrcn2fxjn6d25v4qy3w00b2w8ppg9"))))
+                "18xq8gg1j07gbbxy7r0cc34zwn40mh4fr39zzi8l3z0cymw73qs8"))))
     (properties `((upstream-name . "BANDITS")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2938,13 +3202,13 @@ the posterior densities for the average relative abundance of transcripts.")
 (define-public r-banocc
   (package
     (name "r-banocc")
-    (version "1.20.0")
+    (version "1.22.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "banocc" version))
               (sha256
                (base32
-                "10vaggq1w5jkxd8r2k1mhymzvb7x3h8afwn2pvmcpj022ka7xhbx"))))
+                "0d7ss3df6zcfsh8kgy35ghxa6f27ynjhdbi6mdypgk9q24f64r78"))))
     (properties `((upstream-name . "banocc")))
     (build-system r-build-system)
     (propagated-inputs
@@ -2966,13 +3230,13 @@ estimates for each correlation element.")
 (define-public r-barcodetrackr
   (package
     (name "r-barcodetrackr")
-    (version "1.4.0")
+    (version "1.6.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "barcodetrackR" version))
               (sha256
                (base32
-                "0yxa15xkgqazw31vq4wm8v747bw4qb18m6i602pvynk0n5bgg3d3"))))
+                "1b3z83nkl8csxs88rcbmkkfjps71mwnylvpy3kjzyi02xw0kh0c1"))))
     (properties `((upstream-name . "barcodetrackR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3008,14 +3272,14 @@ retrieval analyses, or similar technologies.")
 (define-public r-biocversion
   (package
     (name "r-biocversion")
-    (version "3.15.2")
+    (version "3.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocVersion" version))
        (sha256
         (base32
-         "0rs4nyza4hqqk204d037gi013135wgfhx5asq2dsdjc9vk5nwzfn"))))
+         "1djp23y131dyx4g22f9r7an177bq0mky94bvpqvc8b14166g0ynw"))))
     (properties `((upstream-name . "BiocVersion")))
     (build-system r-build-system)
     (home-page "https://bioconductor.org/packages/BiocVersion/")
@@ -3028,13 +3292,13 @@ of Bioconductor.")
 (define-public r-biocgenerics
   (package
     (name "r-biocgenerics")
-    (version "0.42.0")
+    (version "0.44.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BiocGenerics" version))
               (sha256
                (base32
-                "0iv9bnpw2hycndwbmjsszqfwrksz6dfr6qcz78jkssc9ldsgmdhc"))))
+                "17dhr7vaph8dnvyklszyas7y8i64mxqxhnfhb6q3l47gq5if8645"))))
     (properties
      `((upstream-name . "BiocGenerics")))
     (build-system r-build-system)
@@ -3048,13 +3312,13 @@ packages.")
 (define-public r-coverageview
   (package
     (name "r-coverageview")
-    (version "1.34.0")
+    (version "1.36.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "CoverageView" version))
               (sha256
                (base32
-                "0mh66l4yh6rpd1r7qbqwh5jkklqyvpfiap0zcqhz9kimssm2pbbp"))))
+                "0cqvwp0ybxgnk9kif3ly780v23pwv4cyh46kk47gxcxqqkjv36ld"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-s4vectors
@@ -3075,13 +3339,13 @@ how the coverage distributed across the genome.")
 (define-public r-cummerbund
   (package
    (name "r-cummerbund")
-   (version "2.38.0")
+   (version "2.40.0")
    (source (origin
              (method url-fetch)
              (uri (bioconductor-uri "cummeRbund" version))
              (sha256
               (base32
-               "1p4anmi436zykp0ir307g75g23kj8b7shxg4r65qq6zdwflphm0q"))))
+               "1fzkhnlgv4zd0slr12d5aichyxsca86p82fyjymiz7f5fqdvqmd9"))))
    (build-system r-build-system)
    (propagated-inputs
     (list r-biobase
@@ -3105,13 +3369,13 @@ used visualizations.")
 (define-public r-dama
   (package
     (name "r-dama")
-    (version "1.68.0")
+    (version "1.70.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "daMA" version))
               (sha256
                (base32
-                "1mpjvl24wsdmpgra3iasgfvy29m71318gj6j1gg6081w0n4cq72m"))))
+                "062nxfry9w674ja3q9zs4df2hvf4wws9jdqpy84g6nb0309vbhqf"))))
     (properties `((upstream-name . "daMA")))
     (build-system r-build-system)
     (propagated-inputs (list r-mass))
@@ -3127,13 +3391,13 @@ factorial microarray data.")
 (define-public r-damefinder
   (package
     (name "r-damefinder")
-    (version "1.8.0")
+    (version "1.10.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "DAMEfinder" version))
               (sha256
                (base32
-                "123ra94bij0m45j2fzqr7fjipj4ld9kgk0kir1zfdbbd5h8h4mdf"))))
+                "0ygsgg51473sycsh367rf8plca6zb1jg2l39zcprwvgpiln8mjdg"))))
     (properties `((upstream-name . "DAMEfinder")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3168,14 +3432,14 @@ offers nice visualization of methyl-circle plots.")
 (define-public r-dearseq
   (package
     (name "r-dearseq")
-    (version "1.8.4")
+    (version "1.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "dearseq" version))
        (sha256
         (base32
-         "1zsqsgf243gq1k57mw11d6apzccnq531mwg2wzw9mjrs1m0jsfzl"))))
+         "1f9hz4jp862jm1grf4qzdvnzp17ri0n1rhfafgkc1j73z6whw1b0"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-compquadform
@@ -3188,6 +3452,7 @@ offers nice visualization of methyl-circle plots.")
            r-pbapply
            r-reshape2
            r-rlang
+           r-scattermore
            r-statmod
            r-survey
            r-tibble
@@ -3206,13 +3471,13 @@ set analyses, and can deal with repeated or longitudinal data.")
 (define-public r-debcam
   (package
     (name "r-debcam")
-    (version "1.14.0")
+    (version "1.16.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "debCAM" version))
               (sha256
                (base32
-                "1ynz57kkxl8nx80zhh1vhhydqb5n6r9d7p69f0k9nj8rp4hdgng7"))))
+                "09dm861adbxdy3ncfdxq46wjr4hpn56c66n64xm9gwzkzsrxyc2a"))))
     (properties `((upstream-name . "debCAM")))
     (build-system r-build-system)
     (inputs (list openjdk))
@@ -3245,13 +3510,13 @@ knowledge can achieve semi-supervised deconvolution of mixtures.")
 (define-public r-decipher
   (package
     (name "r-decipher")
-    (version "2.24.0")
+    (version "2.26.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "DECIPHER" version))
               (sha256
                (base32
-                "045q2bfzgq1yzhyrzvrhrnmlpka4gikrajxxwv05szksy5nvp7q5"))))
+                "01hzxd5f5v2kspx5jd7l21bn87cfgm9aah3zd4d6kyxv98h5a3n1"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biostrings
@@ -3269,13 +3534,13 @@ biological sequences.")
 (define-public r-deco
   (package
     (name "r-deco")
-    (version "1.12.0")
+    (version "1.13.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "deco" version))
               (sha256
                (base32
-                "18n5zgln33c79jbjzjlivs8ihyg8zci6minfqlvagxgzcpa67k0m"))))
+                "0d4abif3v62cbas6hl7pfw8q8jihh7nsra76k9cm6kz54qw4fbnw"))))
     (properties `((upstream-name . "deco")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3311,13 +3576,13 @@ higher deregulation levels.")
 (define-public r-decomplexdisease
   (package
     (name "r-decomplexdisease")
-    (version "1.16.0")
+    (version "1.18.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "DEComplexDisease" version))
               (sha256
                (base32
-                "09a967x1rnv7byjwh29ngjhs67rgg27zblmlzx6pyqlwy5jsp89d"))))
+                "12gw9b0gdwyih51j2gzay6vxhycgc52n8svd0slv6wsbw5rc19lh"))))
     (properties `((upstream-name . "DEComplexDisease")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3344,13 +3609,13 @@ mechanism based on the shared signatures.")
 (define-public r-decomptumor2sig
   (package
     (name "r-decomptumor2sig")
-    (version "2.12.0")
+    (version "2.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "decompTumor2Sig" version))
               (sha256
                (base32
-                "04hg9bbga2s8scjxfd8wjlmr45nzzvh8d6gr0w929sybx4nj2qz6"))))
+                "0agvmgwyk458lhhhspd8243n4897f0q7jf9yqhwsl5wi8011vmqd"))))
     (properties `((upstream-name . "decompTumor2Sig")))
     (build-system r-build-system)
     (inputs (list perl))                ;script/extractSpecColumns.pl
@@ -3387,13 +3652,13 @@ of the signatures to the mutation load of the tumor.")
 (define-public r-deconrnaseq
   (package
     (name "r-deconrnaseq")
-    (version "1.38.0")
+    (version "1.40.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "DeconRNASeq" version))
               (sha256
                (base32
-                "10smk88srxm58hli0fhkdfd6l5z02q58xc9mww39gkn71y0127k6"))))
+                "05rwqchfspy8i9fcj9526rl5vvk0rrgr95nvxzdj0sa2136my8y4"))))
     (properties `((upstream-name . "DeconRNASeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3414,13 +3679,13 @@ single expression profiles.")
 (define-public r-decontam
   (package
     (name "r-decontam")
-    (version "1.16.0")
+    (version "1.18.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "decontam" version))
               (sha256
                (base32
-                "1g9hcfcfnpq6z21069yw0pyzncwznmvxb2xalg4y6y1604dy98q9"))))
+                "0bk7ia2flnxwa99b8mf3xdvap3xqa4pvpsrgbnyapxbaqxr5zf82"))))
     (properties `((upstream-name . "decontam")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3440,13 +3705,13 @@ negative control samples.")
 (define-public r-deconvr
   (package
     (name "r-deconvr")
-    (version "1.2.0")
+    (version "1.4.2")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "deconvR" version))
               (sha256
                (base32
-                "091z3lncamscsvzj63zzbw7dr7vnkn0jwfkm5ljq4112w4rxgrm3"))))
+                "1wa8l9zxdwx32122slnzqyk32klyznxnbziwn98jbp5fxmjka92l"))))
     (properties `((upstream-name . "deconvR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3484,13 +3749,13 @@ make mapping WGBS data to their probe IDs easier.")
 (define-public r-decoupler
   (package
     (name "r-decoupler")
-    (version "2.2.2")
+    (version "2.4.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "decoupleR" version))
        (sha256
-        (base32 "0q1w8yw3bwx8ai5z8rw8lz97w4cplxijq93634hza2vgkig1ck9m"))))
+        (base32 "1872pi2v9gymdpqdhab10ash4b2w8sbk1p635lf0p6s4679syhdi"))))
     (properties `((upstream-name . "decoupleR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3525,13 +3790,13 @@ targeted by a kinase.")
 (define-public r-deepsnv
   (package
     (name "r-deepsnv")
-    (version "1.42.1")
+    (version "1.44.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "deepSNV" version))
               (sha256
                (base32
-                "0bgj1grv3a5bqhcdsw445x49kl3pz367svy6fnrzfsk9bmj46kgn"))))
+                "051xcg9lx8plbfhiacrv1wsxfac0qqspysq960ppibkf4m8crk81"))))
     (properties `((upstream-name . "deepSNV")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3561,13 +3826,13 @@ bases such as COSMIC.")
 (define-public r-delayedarray
   (package
     (name "r-delayedarray")
-    (version "0.22.0")
+    (version "0.24.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "DelayedArray" version))
               (sha256
                (base32
-                "11id63qza9dxl1364gllqafxmx25a0q22jv5q8h709bgc3f0grqy"))))
+                "0nl1v0mxb759wiia2rsxay0cv0q631gqyzgaa10s175lhzsb8r6p"))))
     (properties
      `((upstream-name . "DelayedArray")))
     (build-system r-build-system)
@@ -3591,13 +3856,13 @@ array-like objects like @code{DataFrame} objects (typically with Rle columns),
 (define-public r-derfinderhelper
   (package
     (name "r-derfinderhelper")
-    (version "1.30.0")
+    (version "1.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "derfinderHelper" version))
        (sha256
-        (base32 "0r7zbx5bfmh5cjs12y8d9qwz53nz340gdy3sx7zcn4rzn7rpslp5"))))
+        (base32 "118rjmqy53viczdwj70kaszkpg2r2zbq60k49jg7fqb81prdwy04"))))
     (properties `((upstream-name . "derfinderHelper")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3616,13 +3881,13 @@ calculation in parallel.")
 (define-public r-drimseq
   (package
     (name "r-drimseq")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DRIMSeq" version))
        (sha256
-        (base32 "1dph483ij43ayw0z5dbnp6gwp53ka7k5si1hp3miac7z8dqzv94l"))))
+        (base32 "0cj3fyb99fh30f35ra1gpvzwplszbwvwk33ppgyh1zx2axsx164w"))))
     (properties `((upstream-name . "DRIMSeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3651,13 +3916,13 @@ results.")
 (define-public r-bluster
   (package
    (name "r-bluster")
-   (version "1.6.0")
+   (version "1.8.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "bluster" version))
             (sha256
              (base32
-              "1g496yc7mdhshf6r0n8xhj7ax936ia5z2cx72lqyk2vzzzl5c4v8"))))
+              "1xi9vl09nm95l35kb9n3pn3j9qxw8976lss3cx0ppwnxd2mjr6vy"))))
    (properties `((upstream-name . "bluster")))
    (build-system r-build-system)
    (propagated-inputs
@@ -3681,13 +3946,13 @@ and evaluate clustering results.")
 (define-public r-ideoviz
   (package
     (name "r-ideoviz")
-    (version "1.32.0")
+    (version "1.34.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "IdeoViz" version))
               (sha256
                (base32
-                "1wwh3ifdijhpm58lw7cmnx084xwfxnc7i0206w8rhrjnvnq6ljh3"))))
+                "0jpj8bkfm3jcb5fj0xhh13vqh2dcgdgi4i1qk3wx1301irkk7fgf"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
@@ -3705,14 +3970,14 @@ arbitrary genomic intervals along chromosomal ideogram.")
 (define-public r-infercnv
   (package
     (name "r-infercnv")
-    (version "1.12.0")
+    (version "1.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "infercnv" version))
        (sha256
         (base32
-         "01f021fdxm058733rky46dlvqg7dmf5mn5x9lnq0fspp5665w3bl"))))
+         "11hgw6c67gd3ih5q14a520sjmnlv56qw19z0i6s5pz2slmgflpry"))))
     (properties `((upstream-name . "infercnv")))
     (build-system r-build-system)
     (inputs (list python))
@@ -3736,15 +4001,16 @@ arbitrary genomic intervals along chromosomal ideogram.")
            r-gplots
            r-gridextra
            r-hiddenmarkov
-           r-leiden
+           r-igraph
            r-matrix
            r-paralleldist
            r-phyclust
            r-rann
            r-rcolorbrewer
-           r-reshape
+           r-reshape2
            r-rjags
            r-singlecellexperiment
+           r-seurat
            r-summarizedexperiment
            r-tidyr))
     (native-inputs (list r-knitr))
@@ -3764,13 +4030,13 @@ over-abundant or less-abundant as compared to that of normal cells.")
 (define-public r-iranges
   (package
     (name "r-iranges")
-    (version "2.30.1")
+    (version "2.32.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "IRanges" version))
               (sha256
                (base32
-                "1r01c9lczkchgd9hbxxd6wrd5avhy52mfqjck7l9avjq1jimvzv3"))))
+                "0jvavhl6p2di0n5176gg7shfmpg79rngl2gaw423icswdf8kay89"))))
     (properties
      `((upstream-name . "IRanges")))
     (build-system r-build-system)
@@ -3792,13 +4058,13 @@ possible.")
 (define-public r-isoformswitchanalyzer
   (package
     (name "r-isoformswitchanalyzer")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "IsoformSwitchAnalyzeR" version))
        (sha256
-        (base32 "0n1gb9azxa1mxpsqvw3i3kf72f45nyjj1kgwwrzhd88n3g63lvkd"))))
+        (base32 "06kcx0a7xxzqhf4y8l69my5chh06sfahsaz6anhana7shym3yif5"))))
     (properties `((upstream-name . "IsoformSwitchAnalyzeR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -3994,14 +4260,14 @@ performing parallel computations on multicore machines.")
 (define-public r-affy
   (package
     (name "r-affy")
-    (version "1.74.0")
+    (version "1.76.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "affy" version))
        (sha256
         (base32
-         "02l77y4d4m4jwgkb3jdaskv6shmba5292whp0i29mg9asxv4rdc7"))))
+         "1iix9mq4aph6avs2qr64a7hip461cif56k6npvs5g69nj3rn50gj"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-affyio
@@ -4022,14 +4288,14 @@ analysis.")
 (define-public r-affycomp
   (package
     (name "r-affycomp")
-    (version "1.72.0")
+    (version "1.74.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "affycomp" version))
        (sha256
         (base32
-         "0aq5p56sqpvba0yhgd75302s9bazchh1izgymng6cpb78y5wfpj0"))))
+         "18bxnjcl7cbgwm3yf58608ghwnpci94xgil11zmbpgzgrpv9pkrs"))))
     (properties `((upstream-name . "affycomp")))
     (build-system r-build-system)
     (propagated-inputs (list r-biobase))
@@ -4043,14 +4309,14 @@ measures for Affymetrix Oligonucleotide Arrays.")
 (define-public r-affycompatible
   (package
     (name "r-affycompatible")
-    (version "1.56.0")
+    (version "1.58.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "AffyCompatible" version))
        (sha256
         (base32
-         "0x3lj1jgqq67389rzfklah5p878ns9b4fpdpz455m2gq9sk7qsda"))))
+         "1bg7iqasvfsgd9x3ykgpblqnz1q06g3ifmzj4jf2kn8kxj63wfbl"))))
     (properties
      `((upstream-name . "AffyCompatible")))
     (build-system r-build-system)
@@ -4088,14 +4354,14 @@ Command Console} (AGCC)-compatible sample annotation files.")
 (define-public r-affycontam
   (package
     (name "r-affycontam")
-    (version "1.54.0")
+    (version "1.56.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "affyContam" version))
        (sha256
         (base32
-         "1pyd4rj6pp139kvhh97whi4afvx029w5lglr4mnscw7m3f618v0p"))))
+         "0phf9rvxr45zq9m5rcjsiixmj9ilz518l628l8cd1hzfdk240ffy"))))
     (properties `((upstream-name . "affyContam")))
     (build-system r-build-system)
     (propagated-inputs
@@ -4111,14 +4377,14 @@ problems in CEL-level data to help evaluate performance of quality metrics.")
 (define-public r-affycoretools
   (package
     (name "r-affycoretools")
-    (version "1.68.1")
+    (version "1.70.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "affycoretools" version))
        (sha256
         (base32
-         "05x64hy5jpmg973biwq4q9gzy1n0iqc0pxrix1f6bri1w6vil3ww"))))
+         "17slls8dihjnpm6bynic8cm2fbnfl5iqwimz0wz7c9x44d1bxi4l"))))
     (properties `((upstream-name . "affycoretools")))
     (build-system r-build-system)
     (propagated-inputs
@@ -4153,14 +4419,14 @@ to streamline the more common analyses that a Biostatistician might see.")
 (define-public r-affyio
   (package
     (name "r-affyio")
-    (version "1.66.0")
+    (version "1.68.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "affyio" version))
        (sha256
         (base32
-         "19cw82qvzkz6vh2gm302y7digsf6xif7c9l2q9s6lkx2yflqpgfp"))))
+         "1bdcz9sz4khs7p4ddryc4ir0fwcjrkwqka8y0c9n36ykiv4myfib"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-zlibbioc))
@@ -4177,14 +4443,14 @@ CDF file formats.")
 (define-public r-affxparser
   (package
     (name "r-affxparser")
-    (version "1.68.1")
+    (version "1.70.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "affxparser" version))
        (sha256
         (base32
-         "16x92gwsy7zdyz4md4cw847xn2ymqd6gqsn0rlr2nnf3qmnjnils"))))
+         "0p42rpyh96aph9jr8kiyjvv860jn7m7ji2nrib2vr2nl0jyaxqjs"))))
     (properties `((upstream-name . "affxparser")))
     (build-system r-build-system)
     (home-page "https://github.com/HenrikBengtsson/affxparser")
@@ -4205,14 +4471,14 @@ structure.")
 (define-public r-annotate
   (package
     (name "r-annotate")
-    (version "1.74.0")
+    (version "1.76.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "annotate" version))
        (sha256
         (base32
-         "0x6vddpiw2g713vicf70198x8dlrwf36p8jjygdsfnl56ls5bh2g"))))
+         "06jmnv36y3n6pl1vs6mp14sgyzl4l37g13diaa49k7qwp1kdpl3a"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi
@@ -4232,13 +4498,13 @@ microarrays.")
 (define-public r-annotationdbi
   (package
     (name "r-annotationdbi")
-    (version "1.58.0")
+    (version "1.60.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AnnotationDbi" version))
               (sha256
                (base32
-                "15cwy7lic89jwl3dr7j4pb5bx457jdpvzvylr71624s0p0j9rgwn"))))
+                "1srv0jizmwgmsmgb9cfgy5nbgd3jsgxgzzax6wfsahckb5zihrqp"))))
     (properties
      `((upstream-name . "AnnotationDbi")))
     (build-system r-build-system)
@@ -4262,13 +4528,13 @@ annotation data packages using SQLite data storage.")
 (define-public r-annotationfilter
   (package
     (name "r-annotationfilter")
-    (version "1.20.0")
+    (version "1.22.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "AnnotationFilter" version))
               (sha256
                (base32
-                "082lpcd6yr2nkxndlck2wqqd3nfdx7lnpw8barxgv41q4l7v4ald"))))
+                "0m16kfssxbblf03ykawkmqa038cl90prhb23k6y88g2hwm00wynk"))))
     (properties
      `((upstream-name . "AnnotationFilter")))
     (build-system r-build-system)
@@ -4287,14 +4553,14 @@ used by @code{ensembldb}, @code{Organism.dplyr}, and other packages.")
 (define-public r-annotationforge
   (package
     (name "r-annotationforge")
-    (version "1.38.1")
+    (version "1.40.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "AnnotationForge" version))
        (sha256
         (base32
-         "0lcr79a3570h7zg4z691gxg2vlyqnars5811q0clzinbmq7b4x3v"))))
+         "15shh8rmcx69g3zd256720vh0c3qbly5zrvwm463dws41cjla48x"))))
     (properties
      `((upstream-name . "AnnotationForge")))
     (build-system r-build-system)
@@ -4319,14 +4585,14 @@ databases.  Packages produced are intended to be used with AnnotationDbi.")
 (define-public r-annotationhub
   (package
     (name "r-annotationhub")
-    (version "3.4.0")
+    (version "3.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "AnnotationHub" version))
        (sha256
         (base32
-         "03dmbx43rsv9xv94lk12gpraq47ryc13jijwma3q05hl9wn8xjxs"))))
+         "1hk02q6mwx49khbhydndfa1qry8ylhmwz2dff8845a510hm0di7n"))))
     (properties `((upstream-name . "AnnotationHub")))
     (build-system r-build-system)
     (propagated-inputs
@@ -4360,14 +4626,14 @@ by the user, helping with quick and reproducible access.")
 (define-public r-aroma-light
   (package
     (name "r-aroma-light")
-    (version "3.26.0")
+    (version "3.28.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "aroma.light" version))
        (sha256
         (base32
-         "1240v9wvsf205g998ms19hncki8g6shidg09dy5np9pqpiix4vys"))))
+         "01g9vfkmpfkn9nv71jyybq93lid6x93jbadjahngy98w67n3sin4"))))
     (properties `((upstream-name . "aroma.light")))
     (build-system r-build-system)
     (propagated-inputs
@@ -4384,14 +4650,14 @@ classes.")
 (define-public r-bamsignals
   (package
     (name "r-bamsignals")
-    (version "1.28.0")
+    (version "1.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "bamsignals" version))
        (sha256
         (base32
-         "0ywbxq829hclhr5bb6p77rspxvfs580zlwd2f5kr3an6rdgyx9ky"))))
+         "059pkm5pg9ssd0l8xrm13d0hscqnmlqcb4qb5p4fbzgx6088zg05"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biocgenerics
@@ -4414,13 +4680,13 @@ paired-end data.")
 (define-public r-biobase
   (package
     (name "r-biobase")
-    (version "2.56.0")
+    (version "2.58.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "Biobase" version))
               (sha256
                (base32
-                "1mnxky78an079p60427cjvk4fzilp0xzy6b85fq274qvdcrz8jbv"))))
+                "0rp541nphbcya6kbk1nzrrb05g5m6pxb3yqz5cj873di9vsqlyfv"))))
     (properties
      `((upstream-name . "Biobase")))
     (build-system r-build-system)
@@ -4436,13 +4702,13 @@ on Bioconductor or which replace R functions.")
 (define-public r-biomart
   (package
     (name "r-biomart")
-    (version "2.52.0")
+    (version "2.54.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "biomaRt" version))
               (sha256
                (base32
-                "0yn3kanyrplc89a900xiz33nw1v23mkljvd5isizgs8gzvwzf8xg"))))
+                "0c6agi652kbffqwd1r3c22ncisqaiy3gqbc9fz13767rr71im6lq"))))
     (properties
      `((upstream-name . "biomaRt")))
     (build-system r-build-system)
@@ -4521,13 +4787,13 @@ only one command.")
 (define-public r-biocparallel
   (package
     (name "r-biocparallel")
-    (version "1.30.3")
+    (version "1.32.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BiocParallel" version))
               (sha256
                (base32
-                "1rs3wmasl9mx7f399iclvm0bnvggvjj2a88zbi294r5m8wxqlc92"))))
+                "1fkfbs0n0sdssli7ibrswkfag080kgv8n1zf6ssxx729g1fz3m3h"))))
     (properties
      `((upstream-name . "BiocParallel")))
     (build-system r-build-system)
@@ -4539,18 +4805,16 @@ only one command.")
              ;; Remove generated documentation.
              (for-each delete-file
                        '("inst/doc/BiocParallel_BatchtoolsParam.pdf"
-                         "inst/doc/Introduction_To_BiocParallel.pdf"
                          "inst/doc/Errors_Logs_And_Debugging.pdf"
                          "inst/doc/BiocParallel_BatchtoolsParam.R"
                          "inst/doc/Introduction_To_BiocParallel.R"
-                         "inst/doc/Errors_Logs_And_Debugging.R"))
+                         "inst/doc/Errors_Logs_And_Debugging.R"
+                         "inst/doc/Random_Numbers.R"))
 
              ;; Remove time-dependent macro
              (substitute* '("inst/doc/BiocParallel_BatchtoolsParam.Rnw"
-                            "inst/doc/Introduction_To_BiocParallel.Rnw"
                             "inst/doc/Errors_Logs_And_Debugging.Rnw"
                             "vignettes/BiocParallel_BatchtoolsParam.Rnw"
-                            "vignettes/Introduction_To_BiocParallel.Rnw"
                             "vignettes/Errors_Logs_And_Debugging.Rnw")
                (("\\today") "later"))
 
@@ -4560,7 +4824,7 @@ only one command.")
                 (string-append
                  m "; if (!is.na(Sys.getenv(\"SOURCE_DATE_EPOCH\"))) {set.seed(100)}\n"))))))))
     (propagated-inputs
-     (list r-bh r-codetools r-futile-logger r-snow))
+     (list r-bh r-cpp11 r-codetools r-futile-logger r-snow))
     (native-inputs
      (list r-knitr))
     (home-page "https://bioconductor.org/packages/BiocParallel")
@@ -4574,13 +4838,13 @@ objects.")
 (define-public r-biostrings
   (package
     (name "r-biostrings")
-    (version "2.64.1")
+    (version "2.66.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "Biostrings" version))
               (sha256
                (base32
-                "1wk8nlmp6f6fsjrcb4fb48s3ay38yywwad748i6lfkkcw2pdfw33"))))
+                "1z86s8ncl91pxcjnv8fwvgwjjnd384dn5paylwyymrigph4ca4kk"))))
     (properties
      `((upstream-name . "Biostrings")))
     (build-system r-build-system)
@@ -4602,14 +4866,14 @@ biological sequences or sets of sequences.")
 (define-public r-biovizbase
   (package
     (name "r-biovizbase")
-    (version "1.44.0")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biovizBase" version))
        (sha256
         (base32
-         "1ffzf7yvl47l8v8a50m8g9q33hgwvxg4fcm8ld2yy8hd2zl86zyd"))))
+         "0k56bq3g5vwnd0vkqg7x7v7i9bakwb8s1yl7k5nwj26k4aw96lw6"))))
     (properties `((upstream-name . "biovizBase")))
     (build-system r-build-system)
     (propagated-inputs
@@ -4644,13 +4908,13 @@ effort and encourages consistency.")
 (define-public r-bsgenome
   (package
     (name "r-bsgenome")
-    (version "1.64.0")
+    (version "1.66.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BSgenome" version))
               (sha256
                (base32
-                "17gqrmaf6xxghgrzcansl9gfw3ghkrqp87swlnwgyghqvflr5qxc"))))
+                "1gzpvajw5n3qmym3312qaks450sq3w456kj4gqwaabgpjxbq7frm"))))
     (properties
      `((upstream-name . "BSgenome")))
     (build-system r-build-system)
@@ -4675,14 +4939,14 @@ genome data packages and support for efficient SNP representation.")
 (define-public r-category
   (package
     (name "r-category")
-    (version "2.62.0")
+    (version "2.64.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Category" version))
        (sha256
         (base32
-         "07js03cfdd6gzbzw14iavlqxynfcqszh988v6k1a3h074wxiivqd"))))
+         "1j62b3ycvb27p80k1a1qj4pdf8cjynf5fkj65v74c3l1hgl9qxnh"))))
     (properties `((upstream-name . "Category")))
     (build-system r-build-system)
     (propagated-inputs
@@ -4706,13 +4970,13 @@ analysis.")
 (define-public r-chipseeker
   (package
     (name "r-chipseeker")
-    (version "1.32.1")
+    (version "1.34.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ChIPseeker" version))
               (sha256
                (base32
-                "0l2514wvlc8q7n1zjzfrghdg372sp73z39204bkif3g6pdkcvbcf"))))
+                "0jr9mc79di0r3xrc7m27vwk85qa4fpcwp4nb77pr9s6jbv23773r"))))
     (build-system r-build-system)
     (native-inputs
      (list r-knitr))
@@ -4753,14 +5017,14 @@ annotation, distance to TSS, and overlap of peaks or genes.")
 (define-public r-chipseq
   (package
     (name "r-chipseq")
-    (version "1.46.0")
+    (version "1.48.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "chipseq" version))
        (sha256
         (base32
-         "1vh0hvgnw7ykj401v1q807sl14s4nixp1d8xbm41n01q6w8x834i"))))
+         "1gmspbf5bmlqgbq280lnh4m9bmhzv6d0aj15dmggizsgb9d34vp5"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biocgenerics
@@ -4779,14 +5043,14 @@ experiments.")
 (define-public r-complexheatmap
   (package
     (name "r-complexheatmap")
-    (version "2.12.1")
+    (version "2.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ComplexHeatmap" version))
        (sha256
         (base32
-         "0b4p3ijhdcydfp0j58xlb5dn7d3m2x420n91rl9diqpg4r2gl0s8"))))
+         "1mf0h2j31m57jd3s1sj8ijn9wdgbg452d79drdkxypxqvpm7b927"))))
     (properties
      `((upstream-name . "ComplexHeatmap")))
     (build-system r-build-system)
@@ -4819,14 +5083,14 @@ self-defined annotation graphics.")
 (define-public r-copywriter
   (package
     (name "r-copywriter")
-    (version "2.28.0")
+    (version "2.29.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "CopywriteR" version))
        (sha256
         (base32
-         "1k11kvam96hpg71hz2n9cfzizmb7d1bmq5zfvm34s7fn09is60xb"))))
+         "1h4cyrjwdazgk49yzi9lvya8bfz9r4cpq19hyzikvc81ia8zdxs6"))))
     (properties `((upstream-name . "CopywriteR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -4890,14 +5154,14 @@ distribution.")
 (define-public r-deseq2
   (package
     (name "r-deseq2")
-    (version "1.36.0")
+    (version "1.38.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DESeq2" version))
        (sha256
         (base32
-         "06mvb0jqn2fg96wfwspv0kzpa8xpimzaldrcy8m2d4yk76xwsdr7"))))
+         "0xp3rfhwn8k1bqzqnjzjqlaq8lqyad7kqjhb29vkbxgzjvafvxmk"))))
     (properties `((upstream-name . "DESeq2")))
     (build-system r-build-system)
     (propagated-inputs
@@ -4928,14 +5192,14 @@ distribution.")
 (define-public r-dexseq
   (package
     (name "r-dexseq")
-    (version "1.42.0")
+    (version "1.44.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DEXSeq" version))
        (sha256
         (base32
-         "1dzx9mvm8pvcrwr88rin3flnpmzp3vq8mvspx9s8virqhv1102am"))))
+         "01728hag1c5fh4n0v57k1p9ss5rqgckab4cnj5flp750myi1fbps"))))
     (properties `((upstream-name . "DEXSeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -4973,13 +5237,13 @@ exploration of the results.")
 (define-public r-diffcyt
   (package
     (name "r-diffcyt")
-    (version "1.16.0")
+    (version "1.18.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "diffcyt" version))
        (sha256
-        (base32 "0mysylzmg24g7lm1xan4yklzqmskfgh53j6vjcz2gzakz5rq3rdb"))))
+        (base32 "10xhvksnnn4m1hly16fwmbr28xgym6a9zkqj8y476jph4wpnhc2s"))))
     (properties `((upstream-name . "diffcyt")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5011,14 +5275,14 @@ adapted from transcriptomics.")
 (define-public r-dirichletmultinomial
   (package
     (name "r-dirichletmultinomial")
-    (version "1.38.0")
+    (version "1.40.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DirichletMultinomial" version))
        (sha256
         (base32
-         "15l0h2qz80lmrm5rva3v7lkgddn42igyxxwims57zwpwyhrk9bmx"))))
+         "009nnl3zwcsg6mh7wl3j856dpi7awkyxdy660rqmiskn7m2ah4l1"))))
     (properties
      `((upstream-name . "DirichletMultinomial")))
     (build-system r-build-system)
@@ -5038,13 +5302,13 @@ originally made available by Holmes, Harris, and Quince, 2012, PLoS ONE 7(2):
 (define-public r-dittoseq
   (package
     (name "r-dittoseq")
-    (version "1.8.1")
+    (version "1.10.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "dittoSeq" version))
               (sha256
                (base32
-                "0vi0hcyffaxp6yxsrq95bdlrhr85dvbqm9c7rg6a6blkfgwhlzb4"))))
+                "0sxpwg2cjw70pzdxbdw68nic521w65ryn83mj0pb2m1ncpimin4b"))))
     (properties `((upstream-name . "dittoSeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5082,14 +5346,14 @@ code{dittoColors()}.")
 (define-public r-edaseq
   (package
     (name "r-edaseq")
-    (version "2.30.0")
+    (version "2.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "EDASeq" version))
        (sha256
         (base32
-         "1qnpbmhxvqsma7ihi6yp3ad962xcanlxald84k2szh011ipxj7ws"))))
+         "0hx4als33lvdchz5s6cv2axvjyp0k8p3v0lm51jayhjcjpmihqzp"))))
     (properties `((upstream-name . "EDASeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5122,13 +5386,13 @@ global-scaling and full-quantile normalization.")
 (define-public r-edger
   (package
     (name "r-edger")
-    (version "3.38.4")
+    (version "3.40.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "edgeR" version))
               (sha256
                (base32
-                "1ww69xrg9qrmq7dix2k48j6akgn58ss3340hm7pjvzx508x1j6n6"))))
+                "18vap3qp9blncr4sdl9q1szb4qhm46gldhxy3k3abw9fckcvggwg"))))
     (properties `((upstream-name . "edgeR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5147,14 +5411,14 @@ CAGE.")
 (define-public r-ensembldb
   (package
     (name "r-ensembldb")
-    (version "2.20.2")
+    (version "2.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ensembldb" version))
        (sha256
         (base32
-         "12n21dcimdhgyjzk33m6xbv0m9ihgyzcf66vr1jr5ycv3rq2s7xc"))))
+         "1v1in3imqbwak3v9w99l6hq8kihai5xvpgxvg7imna7jn1w8kmji"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi
@@ -5192,14 +5456,14 @@ chromosome region or transcript models of lincRNA genes.")
 (define-public r-fastseg
   (package
     (name "r-fastseg")
-    (version "1.42.0")
+    (version "1.44.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "fastseg" version))
        (sha256
         (base32
-         "1cr1b1jbgp1z1zpf71kl7mljbm2jpi6b97bf3bll3gnagfm489hy"))))
+         "1m1x7xmbxwa15vzd45h16pnib944f20pwinx1pyhba5hcngkikfi"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase r-biocgenerics r-genomicranges r-iranges
@@ -5219,14 +5483,14 @@ microarrays or GRanges for sequencing data.")
 (define-public r-gage
   (package
     (name "r-gage")
-    (version "2.46.1")
+    (version "2.48.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "gage" version))
        (sha256
         (base32
-         "01y04jcy7a9fksyhj0nq37n1inkrpqf4qv117lflvipbx0dsw4gl"))))
+         "08qvg1cmrln7w5z33r81kz1zjs8fcj3qbxm1crbsazvb6gdpqyyi"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi r-go-db r-graph r-keggrest))
@@ -5247,14 +5511,14 @@ analysis using other methods.")
 (define-public r-genefilter
   (package
     (name "r-genefilter")
-    (version "1.78.0")
+    (version "1.80.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "genefilter" version))
        (sha256
         (base32
-         "1lp3alnljhsil8zylf8rvf8ik4wmsyciy3ij4rr9l4191dkkp4aq"))))
+         "0swdqdyz956gx44crbx3qai0qx7n7yazg3yw7i93djcgahyz3kk7"))))
     (build-system r-build-system)
     (native-inputs
      (list gfortran r-knitr))
@@ -5271,13 +5535,13 @@ high-throughput sequencing experiments.")
 (define-public r-geneoverlap
   (package
     (name "r-geneoverlap")
-    (version "1.32.0")
+    (version "1.34.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "GeneOverlap" version))
               (sha256
                (base32
-                "0nqwa3x9q1hl9nm06hqzzrn00rirc9kj6s320csjlf7x6rcidr93"))))
+                "0ii3ymysqkhyvj204zigpgjny0cglggqmvw311gvgkdi16dib1qs"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-rcolorbrewer r-gplots))
@@ -5290,13 +5554,13 @@ and visualize the results.")
 (define-public r-genomation
   (package
     (name "r-genomation")
-    (version "1.28.0")
+    (version "1.30.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "genomation" version))
               (sha256
                (base32
-                "0rvay7gs4g2wi6h42kln8xwy9b05axj1x8mkfayl6pnnlva6xj79"))))
+                "098ldnh45f48145jfsbdw5dqv5yiqkfci1fy6h6gjz7nh3dvnil5"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biostrings
@@ -5337,13 +5601,13 @@ genomic intervals.  In addition, it can use BAM or BigWig files as input.")
 (define-public r-genomeinfodb
   (package
     (name "r-genomeinfodb")
-    (version "1.32.4")
+    (version "1.34.3")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "GenomeInfoDb" version))
               (sha256
                (base32
-                "0z2bqr0zrl3r2kcqs72ny8p1psf8w1sgbr7qjjknxdv1qp8m2j7v"))))
+                "1pw8ml6b33z7zh7h592xl23l8dy32nqq4lzq20p57n9f0krqj1iv"))))
     (properties
      `((upstream-name . "GenomeInfoDb")))
     (build-system r-build-system)
@@ -5364,13 +5628,13 @@ names in their natural, rather than lexicographic, order.")
 (define-public r-genomicalignments
   (package
     (name "r-genomicalignments")
-    (version "1.32.1")
+    (version "1.34.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "GenomicAlignments" version))
               (sha256
                (base32
-                "09pg7822camyav5zvlpv360sj5gz8q1bhk528qa2da2qsz74a3cz"))))
+                "0y9yjyzch0cn2j4yrwfp0z8qw3yqvl8h1dlrl7ylzy9mwsqc6wg5"))))
     (properties
      `((upstream-name . "GenomicAlignments")))
     (build-system r-build-system)
@@ -5397,13 +5661,13 @@ alignments.")
 (define-public r-genomicfeatures
   (package
     (name "r-genomicfeatures")
-    (version "1.48.4")
+    (version "1.50.2")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "GenomicFeatures" version))
               (sha256
                (base32
-                "15kn5lmdqp7rsh2zlixj7ashsqnv50bs36hapw36qbaz9vgvim4v"))))
+                "10w15j107hy9qb0lh6jmyw7rinfvy3ca34xsskxw3wf25mh6vhzz"))))
     (properties
      `((upstream-name . "GenomicFeatures")))
     (build-system r-build-system)
@@ -5441,14 +5705,14 @@ extracting the desired features in a convenient format.")
 (define-public r-genomicfiles
   (package
     (name "r-genomicfiles")
-    (version "1.32.1")
+    (version "1.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GenomicFiles" version))
        (sha256
         (base32
-         "06ycfna26klx27vvsnlpgv46bymfrc8z0zkpag7nm4m23153ivkz"))))
+         "0k64m9f5y88p90wd87hy0ixj5ly5yi413al9p2bn10b1fjx2c451"))))
     (properties `((upstream-name . "GenomicFiles")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5475,13 +5739,13 @@ provide added flexibility for data combination and manipulation.")
 (define-public r-genomicranges
   (package
     (name "r-genomicranges")
-    (version "1.48.0")
+    (version "1.50.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "GenomicRanges" version))
               (sha256
                (base32
-                "088rv1aclwq265pdg4hmks73nl0125vk0vigyi44n3djkrdx48yn"))))
+                "14m4pvvd9m8kpc7k905km9vib7giq0i9g11bxc1ygw30ifi96966"))))
     (properties
      `((upstream-name . "GenomicRanges")))
     (build-system r-build-system)
@@ -5502,14 +5766,14 @@ manipulating genomic intervals and variables defined along a genome.")
 (define-public r-gostats
   (package
     (name "r-gostats")
-    (version "2.62.0")
+    (version "2.64.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GOstats" version))
        (sha256
         (base32
-         "121ly9vifarg8y7mc468571bbs0xv4sx6sflm5zcdqf0p83yvjrm"))))
+         "07chyfkq8nwxjgnlrrwza8jw996dq0ki4bzdfalj9yl1iac1pnys"))))
     (properties `((upstream-name . "GOstats")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5533,14 +5797,14 @@ testing and other simple calculations.")
 (define-public r-gseabase
   (package
     (name "r-gseabase")
-    (version "1.58.0")
+    (version "1.60.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GSEABase" version))
        (sha256
         (base32
-         "1qhvgyg392fd98h2qnmfmhg7mil5hp9cy3qmkqs4x1bhpv1m978g"))))
+         "0i8fliln3v9sw9x34pqafdx1z6jkys8b11fkz4ihmw8lc8lfd0x5"))))
     (properties `((upstream-name . "GSEABase")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5562,14 +5826,14 @@ Enrichment Analysis} (GSEA).")
 (define-public r-hpar
   (package
     (name "r-hpar")
-    (version "1.38.0")
+    (version "1.40.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "hpar" version))
        (sha256
         (base32
-         "07c6r703d5xp7y9bqmqalxgna2qrbk1h5s0d992m7360k259mgrj"))))
+         "1dls59d2ysk8ngk5c6nx7xqgc2iygbdlzf88gccf2wm8zhy8m3f4"))))
     (build-system r-build-system)
     (native-inputs
      (list r-knitr))
@@ -5582,14 +5846,14 @@ the Human Protein Atlas project.")
 (define-public r-rhtslib
   (package
     (name "r-rhtslib")
-    (version "1.28.0")
+    (version "2.0.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rhtslib" version))
        (sha256
         (base32
-         "07kws6afkxbmxq4w357mwwl712pdd16alvz7iqijjd2x7rjchj2f"))))
+         "1ri76wwv44hgxji2bmlqi6v8gbvhr72q0d6nlgpfgfwb9sgvz62h"))))
     (properties `((upstream-name . "Rhtslib")))
     (build-system r-build-system)
     ;; Without this a temporary directory ends up in the Rhtslib.so binary,
@@ -5611,13 +5875,13 @@ of other R packages who wish to make use of HTSlib.")
 (define-public r-impute
   (package
     (name "r-impute")
-    (version "1.70.0")
+    (version "1.72.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "impute" version))
               (sha256
                (base32
-                "11b0z7py0im6y43k55xpzz5jnvc0ram9rk3n1n4mwhvs0vhy39r2"))))
+                "0862mpbmznizcq5bgnp85dl9q0bip76jkga45gssdrv90wsi2192"))))
     (native-inputs
      (list gfortran))
     (build-system r-build-system)
@@ -5631,14 +5895,14 @@ microarray data, using nearest neighbor averaging.")
 (define-public r-interactivedisplaybase
   (package
     (name "r-interactivedisplaybase")
-    (version "1.34.0")
+    (version "1.36.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "interactiveDisplayBase" version))
        (sha256
         (base32
-         "0fdwx5ch0ch8axdkfiq7zzhhq5hwcvd6kf8fggw9nd3ah1yjwbdg"))))
+         "1j2cz929q9hwkchnzcs3mnbmhg68mm06r9bgylnbll4j5ibqicrz"))))
     (properties
      `((upstream-name . "interactiveDisplayBase")))
     (build-system r-build-system)
@@ -5656,14 +5920,14 @@ Shiny-based display methods for Bioconductor objects.")
 (define-public r-keggrest
   (package
     (name "r-keggrest")
-    (version "1.36.3")
+    (version "1.38.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "KEGGREST" version))
        (sha256
         (base32
-         "0lzb3z6pzm323q70931b7220ygml7jb4g81dybwa79wqiqz15pni"))))
+         "0623p6px259v000pp14c2rknjgivx9c90b626q9bln0qw6wy97zc"))))
     (properties `((upstream-name . "KEGGREST")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5680,13 +5944,13 @@ Shiny-based display methods for Bioconductor objects.")
 (define-public r-lfa
   (package
     (name "r-lfa")
-    (version "1.26.0")
+    (version "1.28.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "lfa" version))
        (sha256
-        (base32 "044866h4fnxmzb3sh9vmrd2smgsbcqgvd19dgwxisi418cad577l"))))
+        (base32 "1l3ip0bsvbz9nagzv47qjh5hf7qf8ffk4hlnkwagngiwyq84vyp1"))))
     (properties `((upstream-name . "lfa")))
     (build-system r-build-system)
     (propagated-inputs (list r-corpcor))
@@ -5701,13 +5965,13 @@ Binomial data via estimation of latent structure in the natural parameter.")
 (define-public r-limma
   (package
     (name "r-limma")
-    (version "3.52.4")
+    (version "3.54.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "limma" version))
               (sha256
                (base32
-                "14xy3qyra2crz31sxgz768mhnhhvcpfhfcigf4xsii643lqcz75h"))))
+                "1jy75nbkhl0kgv4gw88acx58r9f1kywrd36405x6g05xy05bprma"))))
     (build-system r-build-system)
     (home-page "http://bioinf.wehi.edu.au/limma")
     (synopsis "Package for linear models for microarray and RNA-seq data")
@@ -5720,13 +5984,13 @@ different technologies, including microarrays, RNA-seq, and quantitative PCR.")
 (define-public r-made4
   (package
     (name "r-made4")
-    (version "1.70.0")
+    (version "1.72.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "made4" version))
               (sha256
                (base32
-                "1wrv9d2mp799qzy1bsaj4w7wx12gdhfv9qvklz7z41vfz59d6bq5"))))
+                "0ylcigzbahic99afqk1q29d4wczmsqmp2hasvihcykybb440a6f2"))))
     (properties `((upstream-name . "made4")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5749,13 +6013,13 @@ datasets (coinertia analysis).")
 (define-public r-methylkit
   (package
     (name "r-methylkit")
-    (version "1.22.0")
+    (version "1.24.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "methylKit" version))
               (sha256
                (base32
-                "00asjzv05avfg0rrkmfbdqd6xx8d18zi72n3b1kf9wj81z2d2a35"))))
+                "0w6wv8x1jggbvymb07b2z47myf239mwpwbgz5p5yi60qb0k7p2q9"))))
     (properties `((upstream-name . "methylKit")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5823,14 +6087,14 @@ throughput genetic sequencing data sets using regression methods.")
 (define-public r-muscat
   (package
     (name "r-muscat")
-    (version "1.10.1")
+    (version "1.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "muscat" version))
        (sha256
         (base32
-         "1j3zkhqgza92vdykb1yia1jjwsdqra6q9c0jk6p5p2x0778xqgfd"))))
+         "07b1z8rd0zibmv3rm4zggjf49lh37p2bp1h919zcw3n0fy2hax1k"))))
     (properties `((upstream-name . "muscat")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5873,14 +6137,14 @@ platform that mimics both single and multi-sample scRNA-seq data.")
 (define-public r-mutationalpatterns
   (package
     (name "r-mutationalpatterns")
-    (version "3.6.0")
+    (version "3.8.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MutationalPatterns" version))
        (sha256
         (base32
-         "113b2hrc0n47qz144xhky93jcm6qh6flzadq5y0plga5jrz0rnwg"))))
+         "071s1hfxln8zdr303g0ifmajd3kcfxxb6dds0pz67chc2gmgnd9q"))))
     (build-system r-build-system)
     (native-inputs
      (list r-knitr))
@@ -5919,14 +6183,14 @@ in SNV base substitution data.")
 (define-public r-msnbase
   (package
     (name "r-msnbase")
-    (version "2.22.0")
+    (version "2.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MSnbase" version))
        (sha256
         (base32
-         "1xzn0k3c2wn6c6gv90hddy3c201sg927342zrw9ig2xap0r053x3"))))
+         "16apm4qn7sbv06pk2i8k5z7qgkv0yq0h8ri32vikdplqxxh7h0cz"))))
     (properties `((upstream-name . "MSnbase")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5964,14 +6228,14 @@ of mass spectrometry based proteomics data.")
 (define-public r-msnid
   (package
     (name "r-msnid")
-    (version "1.30.0")
+    (version "1.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MSnID" version))
        (sha256
         (base32
-         "1yiw95p40nz0pvq7s4i0xg02r9yqmnknak00z4lkw8jij3w3rkkq"))))
+         "1ljhxbyq5pa32sh44f06cwcdq79xh5nm51bpx1i8xig3bvwyg7p9"))))
     (properties `((upstream-name . "MSnID")))
     (build-system r-build-system)
     (arguments
@@ -6021,14 +6285,14 @@ and irregular enzymatic cleavages, mass measurement accuracy, etc.")
 (define-public r-mzid
   (package
     (name "r-mzid")
-    (version "1.34.0")
+    (version "1.36.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "mzID" version))
        (sha256
         (base32
-         "1q1aqyya9nd494s7m3rdaf3kixipdrwbj825g40kdljwrg85y961"))))
+         "0h5w5ykbziaif6m61pa5x92f2rblfgldvj9vajfhkmxj1b2ks9za"))))
     (properties `((upstream-name . "mzID")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6052,14 +6316,14 @@ specific parser.")
 (define-public r-mzr
   (package
     (name "r-mzr")
-    (version "2.30.0")
+    (version "2.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "mzR" version))
        (sha256
         (base32
-         "1dqa03hb42kbqfg15ksijdkyf9pr54gcl3in4mzjkld5sdi8ncds"))
+         "0p7mkvvaf25si95lpwpr65jm3dzxmgs9i0wilyb2mbxkdcz9vm71"))
        (modules '((guix build utils)))
        (snippet
         '(delete-file-recursively "src/boost"))))
@@ -6103,14 +6367,14 @@ previously been used in XCMS.")
 (define-public r-organism-dplyr
   (package
     (name "r-organism-dplyr")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Organism.dplyr" version))
        (sha256
         (base32
-         "0j29f85d66c45ww3417xx376vpz0mmvga5n7h2cl1sd4h70b55as"))))
+         "1hawn8pp63kal5ml0sm3h1j1wnkq02z64sliyaf6apv7vl60ja9g"))))
     (properties `((upstream-name . "Organism.dplyr")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6142,14 +6406,14 @@ functionality of the @code{TxDb} packages (e.g.,
 (define-public r-organismdbi
   (package
     (name "r-organismdbi")
-    (version "1.38.1")
+    (version "1.40.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "OrganismDbi" version))
        (sha256
         (base32
-         "0mxnxj8x4hc21psz39mf7qwvh1fsn6qyjgl5qffk1xxmasf69619"))))
+         "11l1xqwbqs129vxd6lxdaizpp6j08spyh6799rv5wqmlymap1ykw"))))
     (properties `((upstream-name . "OrganismDbi")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6174,14 +6438,14 @@ the fact that each of these packages implements a select methods.")
 (define-public r-pcaexplorer
   (package
     (name "r-pcaexplorer")
-    (version "2.22.0")
+    (version "2.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "pcaExplorer" version))
        (sha256
         (base32
-         "0xkafpi6y5n8hljdaj183hd5z4ik7lpbklg2cbx1hwfz4n4hh1bl"))))
+         "0gs4az4h5mwnr3s8fq7im5p3mm4mhc0x5amjr2badqkw1fih3jp7"))))
     (properties `((upstream-name . "pcaExplorer")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6229,14 +6493,14 @@ application encapsulates the whole analysis.")
 (define-public r-pcamethods
   (package
     (name "r-pcamethods")
-    (version "1.88.0")
+    (version "1.90.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "pcaMethods" version))
        (sha256
         (base32
-         "1087sl7y707zld7zpf3ly51gnmdp93vn90dwa5440v7qawvg2h9b"))))
+         "1cjmkfpbbfzkx6bi3r9jjx54iwkm4gl8hqa1776hxicq2x2c83s4"))))
     (properties `((upstream-name . "pcaMethods")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6298,14 +6562,14 @@ chromosome.  Both tumor-normal paired and tumor-only analyses are supported.")
 (define-public r-protgenerics
   (package
     (name "r-protgenerics")
-    (version "1.28.0")
+    (version "1.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ProtGenerics" version))
        (sha256
         (base32
-         "04hcgj4q8dbzp1a29rbww2bxxrg679pgys3m09p0ydkpsx76rq05"))))
+         "1k5pg0zbhz9mjsl5i3j33p7qv2adax2lf7yqv6qz229fxxaxs5li"))))
     (properties `((upstream-name . "ProtGenerics")))
     (build-system r-build-system)
     (home-page "https://github.com/lgatto/ProtGenerics")
@@ -6318,14 +6582,14 @@ proteomics packages.")
 (define-public r-rbgl
   (package
     (name "r-rbgl")
-    (version "1.72.0")
+    (version "1.74.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "RBGL" version))
        (sha256
         (base32
-         "0ph089vxla49sng0pdwiyh9rpk9i96cbsx5q2jn46jj4x51ijc7y"))))
+         "0dccxsynfnhjzjk22hr5kg068zbg33g6kyhlhlhqh78582181j9m"))))
     (properties `((upstream-name . "RBGL")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6340,13 +6604,13 @@ the graph algorithms contained in the Boost library.")
 (define-public r-rcas
   (package
     (name "r-rcas")
-    (version "1.22.0")
+    (version "1.24.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "RCAS" version))
               (sha256
                (base32
-                "05sj2ab7bxgf41gkmjaskhqm0198xlir1sw3f73x8rjg14rssmqf"))))
+                "0wja7m3b3zr0m8nwcq5m5appsr09jdwkvvvxzh2r5mhksn0abs6p"))))
     (properties `((upstream-name . "RCAS")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6390,14 +6654,14 @@ library implementing most of the pipeline's features.")
 (define-public r-regioner
   (package
     (name "r-regioner")
-    (version "1.28.0")
+    (version "1.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "regioneR" version))
        (sha256
         (base32
-         "11whi2v211xiz9s7cjl14d8vavlry2fmhvx12rma25wkjmhrpa3f"))))
+         "01anwhz0axdl0g2zsaqz1qdxswxrryarbw6pmn5kmlpz4ipiq049"))))
     (properties `((upstream-name . "regioneR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6421,14 +6685,14 @@ region sets and other genomic features.")
 (define-public r-reportingtools
   (package
     (name "r-reportingtools")
-    (version "2.36.0")
+    (version "2.38.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ReportingTools" version))
        (sha256
         (base32
-         "0r8cdqzfh1jxkghhk3j8x3y9kkmdyg9ibfhsic15jqkmp1im6khh"))))
+         "1nrgnb002qv0yzmrvg59i9b5wzxda0fdkrmdi6vr15g0g7j3yry0"))))
     (properties
      `((upstream-name . "ReportingTools")))
     (build-system r-build-system)
@@ -6471,13 +6735,13 @@ browser.")
 (define-public r-rhdf5
   (package
     (name "r-rhdf5")
-    (version "2.40.0")
+    (version "2.42.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "rhdf5" version))
               (sha256
                (base32
-                "00cp90mnb8p83jiflm6x4x0qf4p7gvgh47jk9jry6j3qyvfqaiff"))))
+                "1vxs227d1295fz8irr6fsv603cw96a801j8njhblvs0cry38d087"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-rhdf5filters r-rhdf5lib))
@@ -6498,14 +6762,14 @@ the available RAM.")
 (define-public r-rhdf5filters
   (package
     (name "r-rhdf5filters")
-    (version "1.8.0")
+    (version "1.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "rhdf5filters" version))
        (sha256
         (base32
-         "1ipg0v8nqz1imj63scqmpiswcxbl4ankg3knfq4p06ic6ypbbmvs"))))
+         "17x2a3122mm3z9qnalw25am2x08cfpm17nwhigabid3ha3d2mgz1"))))
     (properties `((upstream-name . "rhdf5filters")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6524,13 +6788,13 @@ HDF5 datasets.")
 (define-public r-rsamtools
   (package
     (name "r-rsamtools")
-    (version "2.12.0")
+    (version "2.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "Rsamtools" version))
               (sha256
                (base32
-                "1wll703if12qrn0d11ljwf7rqhs4lb27fzyyz1hqwvzn3v361s10"))))
+                "0wd4hsn19msz0fkwfq7gvi97vlfpsbzzw3rjj4b6z7s5a83zir2z"))))
     (properties
      `((upstream-name . "Rsamtools")))
     (build-system r-build-system)
@@ -6589,13 +6853,13 @@ tab-delimited (tabix) files.")
 (define-public r-rtracklayer
   (package
     (name "r-rtracklayer")
-    (version "1.56.1")
+    (version "1.58.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "rtracklayer" version))
               (sha256
                (base32
-                "10qy9s6253mgj871qfqn03i8yw10mz7id4cxfyf67qxczz2xmjls"))))
+                "1qxr0ffmmkbfkbijz7pbks3kvms9k4a5rmma4j9p7ar477fxvlmk"))))
     (build-system r-build-system)
     (arguments
      `(#:phases
@@ -6668,13 +6932,13 @@ differential expression analysis, RNAseq data and related problems.")
 (define-public r-scannotatr
   (package
     (name "r-scannotatr")
-    (version "1.2.0")
+    (version "1.4.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "scAnnotatR" version))
        (sha256
-        (base32 "067q57kabhqd1z8l3d91fw74aaw89nb48gm6fll4hv00nqza3n5b"))))
+        (base32 "0rc035kzbzrxvlcpphzg0yg7q82jvlxpi9xjq8q59hvbpyg1sz93"))))
     (properties `((upstream-name . "scAnnotatR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6705,13 +6969,13 @@ cell types based on specific research needs.")
 (define-public r-scdblfinder
   (package
     (name "r-scdblfinder")
-    (version "1.10.0")
+    (version "1.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "scDblFinder" version))
        (sha256
-        (base32 "0y14dvdm16b3bvlrnz03adfylm1kj6jrp2fwciyldij2lfal90y0"))))
+        (base32 "0gslh28rycx0p6a6fmzbsqy1hg2sn3pp5blxgw01qk9f0ank7szi"))))
     (properties `((upstream-name . "scDblFinder")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6750,13 +7014,13 @@ comprehensive scDblFinder method.")
 (define-public r-scmap
   (package
     (name "r-scmap")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "scmap" version))
        (sha256
-        (base32 "0pfwaa9pgml11b84rpf7afdkmg8kxb4srgpc56571vaz388xrv7l"))))
+        (base32 "14vyjvfs2n4h0xsy25xg4zdmc8dqbg5vyl3qns6f0rh4bsshqdlm"))))
     (properties `((upstream-name . "scmap")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6792,13 +7056,13 @@ different experiment.")
 (define-public r-scry
   (package
     (name "r-scry")
-    (version "1.8.0")
+    (version "1.10.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "scry" version))
               (sha256
                (base32
-                "16mj21r91jy8ircdz8rfrdli9gjy0hrx90kf6ghs305d3d4dl193"))))
+                "0vx6fi8hnxms6d3hm3qxkrdx1qpyd7vhwdk7ds98ads070miqr21"))))
     (properties `((upstream-name . "scry")))
     (build-system r-build-system)
     (propagated-inputs
@@ -6824,14 +7088,14 @@ single-cell RNA-seq.")
 (define-public r-seqlogo
   (package
     (name "r-seqlogo")
-    (version "1.62.0")
+    (version "1.64.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "seqLogo" version))
        (sha256
         (base32
-         "1lk3238m17acmd6lgjjbpscyxw8fm63wv34kbbr478wcih1wbwxr"))))
+         "1xlxi1iaqj7iabzbx15j6pk4551dyj6pa6a6qf5ffr3v7k2pmznp"))))
     (properties `((upstream-name . "seqLogo")))
     (build-system r-build-system)
     (native-inputs
@@ -6847,13 +7111,13 @@ Stephens (1990).")
 (define-public r-seqpattern
   (package
     (name "r-seqpattern")
-    (version "1.28.0")
+    (version "1.30.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "seqPattern" version))
               (sha256
                (base32
-                "0nrrlr1nl9zxmp88qq8jn7wgmda6jh0xvp4nph94w4nwjsyb7xqn"))))
+                "17nvxy8kdc1k0kyf0qny6jp3gzr024q37mmh5x18jjr794hnf9s5"))))
     (properties
      `((upstream-name . "seqPattern")))
     (build-system r-build-system)
@@ -6870,14 +7134,14 @@ reference point and sorted by a user defined feature.")
 (define-public r-shortread
   (package
     (name "r-shortread")
-    (version "1.54.0")
+    (version "1.56.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ShortRead" version))
        (sha256
         (base32
-         "0303198b4v2wjah9kc829kn01030996l6di4jpf8q5ccd212rjhq"))))
+         "1dvnjjc6cwn9wicki3ff3w3zx7i0szj0lnfw4n6lbmipg4ia5bkb"))))
     (properties `((upstream-name . "ShortRead")))
     (build-system r-build-system)
     (inputs
@@ -6913,14 +7177,14 @@ ungapped alignment formats.")
 (define-public r-simplifyenrichment
   (package
     (name "r-simplifyenrichment")
-    (version "1.6.1")
+    (version "1.8.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "simplifyEnrichment" version))
        (sha256
         (base32
-         "0qblgdxmr7zc981529cca3ykakql618q1im6gaxw8pwws5jgpyk6"))))
+         "130x5hy6jzglc6clwanh2kmhw567i802w620ffs3977kjfpjsjgy"))))
     (properties
      `((upstream-name . "simplifyEnrichment")))
     (build-system r-build-system)
@@ -6954,13 +7218,13 @@ and comparing the clusterings.")
 (define-public r-transcriptr
   (package
     (name "r-transcriptr")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "transcriptR" version))
        (sha256
-        (base32 "1zc6aasd5nzwl9jxr0rdriiq85adqdbfi5b9m3jyf69pa71sgy03"))))
+        (base32 "03v8xn777vyma82ma5dzk07i1g7406cvsybdz4bf6hj8bgx5ynw7"))))
     (properties `((upstream-name . "transcriptR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -7004,14 +7268,14 @@ able to deal also with novel and case specific events.")
 (define-public r-trajectoryutils
   (package
     (name "r-trajectoryutils")
-    (version "1.4.0")
+    (version "1.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "TrajectoryUtils" version))
        (sha256
         (base32
-         "07hcr3zplxlzlwc13wh9006m5kaqm57cm1b2x74bpp857f2q93dj"))))
+         "130w4vpsmrkg458n3wbhvlchg171gjqybvs2w14bxa608f3fzw03"))))
     (properties
      `((upstream-name . "TrajectoryUtils")))
     (build-system r-build-system)
@@ -7031,13 +7295,13 @@ structures to hold pseudotime inference results.")
 (define-public r-slingshot
   (package
    (name "r-slingshot")
-   (version "2.4.0")
+   (version "2.6.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "slingshot" version))
             (sha256
              (base32
-              "0xapi66l5z2qdqns3fcjqcjal6npqj7rxra60lwjvbrq49pq69p2"))))
+              "00h9iid2z9r55l4hlaa1q0nkbcfq0f7k2afkw4ymjwhm1b8yqj33"))))
    (build-system r-build-system)
    (propagated-inputs
     (list r-igraph
@@ -7063,13 +7327,13 @@ graph construction.")
 (define-public r-stager
   (package
     (name "r-stager")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "stageR" version))
        (sha256
-        (base32 "0ns3ih6l4na6irshrc5iy4d9qf7hrnqq3ndnlcjb2i1cn38l2w9y"))))
+        (base32 "1layvv9akzijw2br9jzw6cwxn2rimha4m48fm8wn465n1nqcns0m"))))
     (properties `((upstream-name . "stageR")))
     (build-system r-build-system)
     (propagated-inputs (list r-summarizedexperiment))
@@ -7086,13 +7350,13 @@ Biology at
 (define-public r-stringdb
   (package
     (name "r-stringdb")
-    (version "2.8.4")
+    (version "2.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "STRINGdb" version))
        (sha256
-        (base32 "1jn6080v6097zpqsr4gfbx31gqqdhpzjrk63avk3v3xwawmf2379"))))
+        (base32 "1md79vx4270wgh07g3m1mypdki1b9d4a558zxplcalwppqh0dsmp"))))
     (properties `((upstream-name . "STRINGdb")))
     (build-system r-build-system)
     (propagated-inputs
@@ -7119,13 +7383,13 @@ that integrates the various evidences.")
 (define-public r-structuralvariantannotation
   (package
     (name "r-structuralvariantannotation")
-    (version "1.12.0")
+    (version "1.13.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "StructuralVariantAnnotation" version))
        (sha256
-        (base32 "0f3x74ic3blg8nm5xlv79k0n8j3fpl98mmhfanqfzmdl0g3j6wx6"))))
+        (base32 "11z3acsbaifrxkghd7i8503ki9s1lc6c22880yna6qcfprlzb44g"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-assertthat
@@ -7156,13 +7420,13 @@ involving two separate genomic loci encoded as GRanges objects.")
 (define-public r-summarizedexperiment
   (package
     (name "r-summarizedexperiment")
-    (version "1.26.1")
+    (version "1.28.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "SummarizedExperiment" version))
               (sha256
                (base32
-                "02vlqzmslyijs09jl0gdjxqjjnnl4yqbqqqlb4vb7nr0fspmyz39"))))
+                "0897v6x1ki4m7kajnd60yv5qj6xa1293sj572b4dhcnfjvsf9rcn"))))
     (properties
      `((upstream-name . "SummarizedExperiment")))
     (build-system r-build-system)
@@ -7190,14 +7454,14 @@ samples.")
 (define-public r-sva
   (package
     (name "r-sva")
-    (version "3.44.0")
+    (version "3.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "sva" version))
        (sha256
         (base32
-         "0ka259rn0la0hjslj7w24q1dyyh79h84nw6mxp7armqbfjb207a4"))))
+         "0c1b7w4rvyy8i0jygj8g9xgf46rmgx8bpdlp2x4fdjr9xsrsl23g"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-edger
@@ -7221,14 +7485,14 @@ unmodeled, or latent sources of noise.")
 (define-public r-systempiper
   (package
     (name "r-systempiper")
-    (version "2.2.2")
+    (version "2.4.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "systemPipeR" version))
        (sha256
         (base32
-         "1yybbff29gwv6rm0nw4yjw73bbl5prfj8gj4zky917smjfd459im"))))
+         "0lwc4d4k6qmnwsh8fpp5rmiaxhzwl2f0dhzs23ska5xy04466r49"))))
     (properties `((upstream-name . "systemPipeR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -7264,13 +7528,13 @@ annotation infrastructure.")
 (define-public r-topgo
   (package
     (name "r-topgo")
-    (version "2.48.0")
+    (version "2.50.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "topGO" version))
               (sha256
                (base32
-                "125r42ymk1irjmwk4sywjkcshs71s26p3zsvryfdvf56k5w162v6"))))
+                "1ripdn7mcabh96bm4p807dbwj7jv05a54kss4snhz84svqq383m4"))))
     (properties
      `((upstream-name . "topGO")))
     (build-system r-build-system)
@@ -7297,13 +7561,13 @@ dependencies between GO terms can be implemented and applied.")
 (define-public r-tximport
   (package
     (name "r-tximport")
-    (version "1.24.0")
+    (version "1.26.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "tximport" version))
               (sha256
                (base32
-                "1cnra82pvwz79a1hkw0phc6aa3v43r5p4nx8xyx5wzmkd7rjkc8x"))))
+                "1w1m6r85a5nvcfxbkq5dmczaar8vf3vbrgrmxqkjqhlpcq58z5ng"))))
     (build-system r-build-system)
     (native-inputs
      (list r-knitr))
@@ -7355,13 +7619,13 @@ R, enabling interactive analysis and visualization of genome-scale data.")
 (define-public r-variantannotation
   (package
     (name "r-variantannotation")
-    (version "1.42.1")
+    (version "1.44.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "VariantAnnotation" version))
               (sha256
                (base32
-                "12d5hkx6pby6l2asyg4jp4jb2x17ybwhqd55rl64h37mwcndbdg1"))))
+                "08rm27jcx6amawqdh59291r0qzkr5cdhbhm0xbjbd5mvdpp1icl8"))))
     (properties
      `((upstream-name . "VariantAnnotation")))
     (propagated-inputs
@@ -7393,14 +7657,14 @@ coding changes and predict coding outcomes.")
 (define-public r-vsn
   (package
     (name "r-vsn")
-    (version "3.64.0")
+    (version "3.66.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "vsn" version))
        (sha256
         (base32
-         "1ja7vdjvgx671l57f9fzfn4vc6q7xzfmqs4krg2rdyfaaf531gqf"))))
+         "1k77rg5jf646m1pn59qhlsbb9fzhlpnrj4dzxagknawcbpnnjl0z"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-affy r-biobase r-ggplot2 r-lattice r-limma))
@@ -7462,13 +7726,13 @@ inference.")
 (define-public r-xina
   (package
     (name "r-xina")
-    (version "1.14.0")
+    (version "1.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "XINA" version))
        (sha256
-        (base32 "03gf7mqpnwx12kny9fsaskgrw83b0wi2cf1j4dbq46pfxjx34v1g"))))
+        (base32 "1c97lsb5shixh4n4mi9kh4gz4qnia9vq736rnzxbs03n5bvlmwlq"))))
     (properties `((upstream-name . "XINA")))
     (build-system r-build-system)
     (propagated-inputs
@@ -7498,13 +7762,13 @@ molecular functions, respectively, and produces intuitive graphical outputs.")
 (define-public r-xmapbridge
   (package
     (name "r-xmapbridge")
-    (version "1.54.0")
+    (version "1.56.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "xmapbridge" version))
        (sha256
-        (base32 "1n3nxc4jwxf5z32i70sza52nyk29adhp8vc3hac7r5b8mbi6gg10"))))
+        (base32 "0wxr3db2daj4xlr9df6iqwm00m71kln7rhqnq2ckdsricblanhs7"))))
     (properties `((upstream-name . "xmapbridge")))
     (build-system r-build-system)
     (home-page "https://git.bioconductor.org/packages/xmapbridge")
@@ -7525,13 +7789,13 @@ describing each of the graphs.")
 (define-public r-xvector
   (package
     (name "r-xvector")
-    (version "0.36.0")
+    (version "0.38.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "XVector" version))
               (sha256
                (base32
-                "1f3sbqy279gb9k13l73j00ixywa1havlqy81zx766r1xkz15nvhk"))))
+                "0ygdyh3s4qsaay930a5lbnmgh6a4gqp5ck9ww466yk0jyk1hxfp9"))))
     (properties
      `((upstream-name . "XVector")))
     (build-system r-build-system)
@@ -7559,13 +7823,13 @@ describing each of the graphs.")
 (define-public r-zlibbioc
   (package
     (name "r-zlibbioc")
-    (version "1.42.0")
+    (version "1.44.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "zlibbioc" version))
               (sha256
                (base32
-                "0w0y9jixdk6akmasn55g9g0nhlh93hbca5bwx5w1fypnvqrqpxzv"))))
+                "0c75mf0iw6bgwrn3zxpz1dz03aw7p6a1mfhssk6i1mp24avic9lb"))))
     (properties
      `((upstream-name . "zlibbioc")))
     (build-system r-build-system)
@@ -7578,13 +7842,13 @@ libraries for systems that do not have these available via other means.")
 (define-public r-zellkonverter
   (package
     (name "r-zellkonverter")
-    (version "1.6.5")
+    (version "1.8.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "zellkonverter" version))
        (sha256
-        (base32 "0rxpjkisjj1xjchjjm72k8za5hn48wbdahmbllljvxm5ii6k36k6"))))
+        (base32 "0b14v6lyhfapmfj8j729k5cmgxc4df6wsk2rds0q4y6z4hiwgmxy"))))
     (properties `((upstream-name . "zellkonverter")))
     (build-system r-build-system)
     (propagated-inputs
@@ -7610,14 +7874,14 @@ saving AnnData objects to disk.")
 (define-public r-geneplotter
   (package
     (name "r-geneplotter")
-    (version "1.74.0")
+    (version "1.76.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "geneplotter" version))
        (sha256
         (base32
-         "13230mzrdralnvf9jp032s16a8mk3kx5476nnvpa4pvcgp1i1ijc"))))
+         "094v4skdvsnc7bp3acj801ih022w9k96f2b857326vd19khz0ava"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotate
@@ -7635,14 +7899,14 @@ saving AnnData objects to disk.")
 (define-public r-oligoclasses
   (package
     (name "r-oligoclasses")
-    (version "1.58.0")
+    (version "1.60.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "oligoClasses" version))
        (sha256
         (base32
-         "1m4x50gl1fm5waa531v7ml0q229q65qn9cgiwnvjg721fvra7mdk"))))
+         "1ik9xfx6g4gf54hm5f5prip1iz6694czpbhlgwd3p9qh8ddndgp8"))))
     (properties `((upstream-name . "oligoClasses")))
     (build-system r-build-system)
     (propagated-inputs
@@ -7670,14 +7934,14 @@ packages.")
 (define-public r-oligo
   (package
     (name "r-oligo")
-    (version "1.60.0")
+    (version "1.62.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "oligo" version))
        (sha256
         (base32
-         "0y7j96rafm9b85sxq2483i73685i3j67lk33fn8nfcav6lmsv5vy"))))
+         "0l6yb58frh4c080k6h8wyipc5kiz4qi7jimnr62jg8d737rrvnk2"))))
     (properties `((upstream-name . "oligo")))
     (build-system r-build-system)
     (inputs (list zlib))
@@ -7706,14 +7970,14 @@ Affymetrix (CEL files) and NimbleGen arrays (XYS files).")
 (define-public r-qvalue
   (package
     (name "r-qvalue")
-    (version "2.28.0")
+    (version "2.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "qvalue" version))
        (sha256
         (base32
-         "0cvhm5cldcnnxwa293dig1pj9lvj2hnz9zh4gfr25sw0xlcjzmyw"))))
+         "1dsia1c9ir989aqrgl5j5v4bysm3pyw9225yrcajiwgl8fxymph4"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-ggplot2 r-reshape2))
@@ -7761,13 +8025,13 @@ problems in genomics, brain imaging, astrophysics, and data mining.")
 (define-public r-apeglm
   (package
    (name "r-apeglm")
-   (version "1.18.0")
+   (version "1.20.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "apeglm" version))
             (sha256
              (base32
-              "1ppwk4g66x46hpqsfsvhl12398d1srqr47nmp0y2gz212kff0rby"))))
+              "1hk2y7r734wdd56f18l03kyq9p35kv653a5f7z2cjkq37gvcqrd1"))))
    (properties `((upstream-name . "apeglm")))
    (build-system r-build-system)
    (propagated-inputs
@@ -7788,13 +8052,13 @@ posterior for individual coefficients.")
 (define-public r-greylistchip
   (package
    (name "r-greylistchip")
-   (version "1.28.1")
+   (version "1.30.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "GreyListChIP" version))
             (sha256
              (base32
-              "0w52vwvjarql19bsv40b80yn701qx8c9d0clsjhj85wmzj2p6dhg"))))
+              "02qzvs8fmh79g4cc5j2gxj1wazpmly7vjr527qlsgi3jmc3swxgz"))))
    (properties `((upstream-name . "GreyListChIP")))
    (build-system r-build-system)
    (propagated-inputs
@@ -7815,14 +8079,14 @@ signal in the input, that lead to spurious peaks during peak calling.")
 (define-public r-diffbind
   (package
     (name "r-diffbind")
-    (version "3.6.4")
+    (version "3.8.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DiffBind" version))
        (sha256
         (base32
-         "035xczcir4q7yj6x9m3yq3dpvbfas9la925avni8147cwhybagqr"))))
+         "1wgnrd1xpl49pdxxjzzl0v9535naapwp3ayqzvrx3z4m6iai2awj"))))
     (properties `((upstream-name . "DiffBind")))
     (build-system r-build-system)
     (propagated-inputs
@@ -7893,13 +8157,13 @@ processing to visualization and annotation.")
 (define-public r-mbkmeans
   (package
     (name "r-mbkmeans")
-    (version "1.12.0")
+    (version "1.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "mbkmeans" version))
               (sha256
                (base32
-                "1f5krzlyqljz763vkp1a50danjn78xhn35s8qqdvzrmwyx0fzphg"))))
+                "1ghv2j88p3sppqph3wxpm8z84nw7bi4idkn11wf806d8h1krfjm7"))))
     (build-system r-build-system)
     (native-inputs
      (list r-knitr))
@@ -7925,14 +8189,14 @@ large datasets, including support for on-disk data representation.")
 (define-public r-multtest
   (package
     (name "r-multtest")
-    (version "2.52.0")
+    (version "2.54.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "multtest" version))
        (sha256
         (base32
-         "037wcmwk1wvhjxgmlvnk289pkwishi1753ajkmy9x14xlmldix82"))))
+         "0ciz0fl0pzm4hjqw8af32s540lwjbkwvwnzgbfwadax40hgjs0g7"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-survival r-biocgenerics r-biobase r-mass))
@@ -7960,13 +8224,13 @@ expressed genes in DNA microarray experiments.")
 (define-public r-graph
   (package
     (name "r-graph")
-    (version "1.74.0")
+    (version "1.76.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "graph" version))
               (sha256
                (base32
-                "1b8hrjwjg82kicls1496fxfzv75xjvq2k6r9apzsd3qlbyg3ilg4"))))
+                "1hdbxjvgkxb9m341i9qbskb41g2z8qifkhgkpj2xb20s2dnxn3cc"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biocgenerics))
@@ -8053,14 +8317,14 @@ determining dependencies between variables, code improvement suggestions.")
 (define-public r-chippeakanno
   (package
     (name "r-chippeakanno")
-    (version "3.30.1")
+    (version "3.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ChIPpeakAnno" version))
        (sha256
         (base32
-         "0a26glldxczcfymjvd45gv5m4hympziivm6wwx4ab9wld7n43l8y"))))
+         "13syh3mvqpaqgfndcrwdmn7815f4myxhzjga9a9q3lspci25rvy6"))))
     (properties `((upstream-name . "ChIPpeakAnno")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8107,13 +8371,13 @@ enrichedGO (addGeneIDs).")
 (define-public r-matrixgenerics
   (package
    (name "r-matrixgenerics")
-   (version "1.8.1")
+   (version "1.10.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "MatrixGenerics" version))
             (sha256
              (base32
-              "1liblnpziyyjxzrhdd5d89ilvfqqhbl87h3hsmdm0kwnmc73r37f"))))
+              "05a83gh5bvgadi2msgql5nmcgr8zp398rhdbmiqna608hqbymyq9"))))
    (properties
     `((upstream-name . "MatrixGenerics")))
    (build-system r-build-system)
@@ -8134,12 +8398,12 @@ incompatibilities.")
 (define-public r-marray
   (package
     (name "r-marray")
-    (version "1.74.0")
+    (version "1.76.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "marray" version))
               (sha256
-               (base32 "0awfz0akz3sylyw1jxhxgadv1rqdzvy9v11933yxkl9a8m9ngm8i"))))
+               (base32 "1bad4cjxv22h6vxxn86mxp7xvxhhzj81pikxq3h3hc2a858qfkgs"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-limma))
@@ -8153,12 +8417,12 @@ normalization and quality checking.")
 (define-public r-cghbase
   (package
    (name "r-cghbase")
-   (version "1.56.0")
+   (version "1.58.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "CGHbase" version))
             (sha256
-             (base32 "1q8yy60r4g5nyv2gbfdgk192xd73c0rrjr668d5616ddb7sx8wcr"))))
+             (base32 "01n1z525h4h6yr3jfalgjg2g6lhd77sc3n33q0485x7l6xqv1dvp"))))
    (properties `((upstream-name . "CGHbase")))
    (build-system r-build-system)
    (propagated-inputs
@@ -8172,12 +8436,12 @@ the @code{arrayCGH} packages.")
 (define-public r-cghcall
   (package
    (name "r-cghcall")
-   (version "2.58.0")
+   (version "2.60.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "CGHcall" version))
             (sha256
-             (base32 "1qpsibp4gb09sn6fkwwrdjkh3a28lqfbk18c6fvn4m386j96ps65"))))
+             (base32 "0860w2vf662qqii09pjdx85yl346jcldxiikhbwv0vg86blwb2g2"))))
    (properties `((upstream-name . "CGHcall")))
    (build-system r-build-system)
    (propagated-inputs
@@ -8191,12 +8455,12 @@ the @code{arrayCGH} packages.")
 (define-public r-qdnaseq
   (package
     (name "r-qdnaseq")
-    (version "1.32.0")
+    (version "1.34.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "QDNAseq" version))
               (sha256
-               (base32 "0s360s72lfn9vjml88gg1m40n61s0dc66ilzgfjdcp65djdxxfvm"))))
+               (base32 "1qv3vmc6i7r35pqhi45hmvg8h7v3bl82lv7yifs59k250zsdls59"))))
     (properties `((upstream-name . "QDNAseq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8223,14 +8487,14 @@ respectively.")
 (define-public r-bayseq
   (package
     (name "r-bayseq")
-    (version "2.30.0")
+    (version "2.31.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "baySeq" version))
        (sha256
         (base32
-         "1yqykndyv32s2rk7x86qf410qr0pigc8z4gdkl8vhj4dgyr47n2j"))))
+         "0lq2wfm3ibrpha9mqhhp6dgsx4jm2kwxvvrj0b62dzqspvg743wh"))))
     (properties `((upstream-name . "baySeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8247,14 +8511,14 @@ more complex hypotheses) via empirical Bayesian methods.")
 (define-public r-chipcomp
   (package
     (name "r-chipcomp")
-    (version "1.26.0")
+    (version "1.28.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ChIPComp" version))
        (sha256
         (base32
-         "06q34y59gf1iz0rs7y5x8ndy1wa95j65rfmz37aym5c46ijqsnq0"))))
+         "1wnc7zrnnxk3nlk2l9y4il75dzirndp4vs5ivxn5rzqr6p7h4bhw"))))
     (properties `((upstream-name . "ChIPComp")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8281,14 +8545,14 @@ datasets.")
 (define-public r-riboprofiling
   (package
     (name "r-riboprofiling")
-    (version "1.26.0")
+    (version "1.28.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "RiboProfiling" version))
        (sha256
         (base32
-         "08m4rc530bkzcc43iwzg2fw9cjlf4wc2d8akv5vblsb42xdn8sqp"))))
+         "0wmmpcabi1ngwmvfhxkp44kj1wvzyrcckkrzpjlzcq016lr67iwn"))))
     (properties `((upstream-name . "RiboProfiling")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8322,14 +8586,14 @@ assessment, principal component analysis on codon coverage.")
 (define-public r-riboseqr
   (package
     (name "r-riboseqr")
-    (version "1.30.0")
+    (version "1.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "riboSeqR" version))
        (sha256
         (base32
-         "1zs3y0icsqrndjp9wwqz3jxysvyc9pch45y49j6g9b5b2l44ma26"))))
+         "0la8kmxxh5jnqsrmmvyhi313bjdbqkiq16hcxar6mgyjhxlsm610"))))
     (properties `((upstream-name . "riboSeqR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8350,14 +8614,14 @@ parsing of genetic sequencing data from ribosome profiling experiments.")
 (define-public r-interactionset
   (package
     (name "r-interactionset")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "InteractionSet" version))
        (sha256
         (base32
-         "0qjimx25jvm8siq8hmlbf2z6mknzpbq945p06fsj826k57bpcsm5"))))
+         "14fb780f2g24ay28dy9xkmfziavbkj75v4vc2cmqbxfdsfp4yn0w"))))
     (properties
      `((upstream-name . "InteractionSet")))
     (build-system r-build-system)
@@ -8384,14 +8648,14 @@ experiments.")
 (define-public r-genomicinteractions
   (package
     (name "r-genomicinteractions")
-    (version "1.30.0")
+    (version "1.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GenomicInteractions" version))
        (sha256
         (base32
-         "0aph1hja5vfprxs3jl4zd1inhvih6m3v1p3jkm6w7xpj3jzvmgbx"))))
+         "0l14hz5pr0wlin46y8ycpvk5hp2ld9ajx11y85rw5hlwv50byfbb"))))
     (properties
      `((upstream-name . "GenomicInteractions")))
     (build-system r-build-system)
@@ -8425,14 +8689,14 @@ information and producing various plots and statistics.")
 (define-public r-ctc
   (package
     (name "r-ctc")
-    (version "1.70.0")
+    (version "1.72.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ctc" version))
        (sha256
         (base32
-         "0c9pgp25dqx12fmi4cqm7xyxjmy6g7wv9vbljgdjghaij2lrc4pb"))))
+         "098a65fk9la639sqihhsghhgb3hyzv35j6akph908zwq5grsv0c5"))))
     (build-system r-build-system)
     (propagated-inputs (list r-amap))
     (home-page "https://bioconductor.org/packages/ctc/")
@@ -8445,14 +8709,14 @@ trees and clusters to other programs.")
 (define-public r-goseq
   (package
     (name "r-goseq")
-    (version "1.48.0")
+    (version "1.50.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "goseq" version))
        (sha256
         (base32
-         "1w0rwzhqkvp2x7y5v0qcyjbss0p95gb1jrnx5sdkqginbvrmrd48"))))
+         "0x89lv84l3qcahca54njcza326553zij2xyagy18mwlprdrq4iy8"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi
@@ -8471,14 +8735,14 @@ defined categories which are over/under represented in RNA-seq data.")
 (define-public r-glimma
   (package
     (name "r-glimma")
-    (version "2.6.0")
+    (version "2.8.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Glimma" version))
        (sha256
         (base32
-         "1k17ay09vhb2hakg1vrgvpp1zliavlj7cdkxaal162bc3v8pyvyz"))))
+         "1fskabpd3xlrbhqvzam9ibpxmbdys7y1b265np8hz4k704ww1g22"))))
     (properties `((upstream-name . "Glimma")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8504,14 +8768,14 @@ information.")
 (define-public r-rots
   (package
     (name "r-rots")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ROTS" version))
        (sha256
         (base32
-         "021a578p8kcl5yd9myiy0h2qp10r30ggnip2kp6xs7dx8nzic96r"))))
+         "1wirblji4ckiwrvnh14cfwc9cjypazbaqr00ka5ndyz39cc31shn"))))
     (properties `((upstream-name . "ROTS")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8527,14 +8791,14 @@ in omics data.")
 (define-public r-plgem
   (package
     (name "r-plgem")
-    (version "1.68.0")
+    (version "1.70.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "plgem" version))
        (sha256
         (base32
-         "07zxflxcay17hxjw3wh5kfdwl2x8537csb18p1qzmyrkvscnja77"))))
+         "0hnhfdrlg4907dc4s17cy4kgmq5nr616f1wi7jn72acxwqfl4bk8"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase r-mass))
@@ -8551,14 +8815,14 @@ genes or proteins in these datasets.")
 (define-public r-inspect
   (package
     (name "r-inspect")
-    (version "1.26.0")
+    (version "1.28.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "INSPEcT" version))
        (sha256
         (base32
-         "0jx887vhxwd8zlqajr9czvn9nx88ryyxlnl58hxrlajjpcjkz9ax"))))
+         "126cbanan2fr916spacw6lm8hzkys56k7z3gq0r351zd7q13gky3"))))
     (properties `((upstream-name . "INSPEcT")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8597,14 +8861,14 @@ modeling the rates that determines changes in mature mRNA levels.")
 (define-public r-dnabarcodes
   (package
     (name "r-dnabarcodes")
-    (version "1.26.0")
+    (version "1.28.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DNABarcodes" version))
        (sha256
         (base32
-         "0n2qlvpcjhrxr3br27gz9vhwcpf7sn6g4xdjazvvi3gqcgk90xc6"))))
+         "18sivwzl8gk52dnhwls0i4imw78rkjlwbfrcaas1i53q0bmw15i5"))))
     (properties `((upstream-name . "DNABarcodes")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8624,14 +8888,14 @@ demultiplexed, i.e. assigned to their original reference barcode.")
 (define-public r-ruvseq
   (package
     (name "r-ruvseq")
-    (version "1.30.0")
+    (version "1.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "RUVSeq" version))
        (sha256
         (base32
-         "001h07b074hvj16bjdp9llb9psphw7r6kpwhq61bj4519y6lpg7x"))))
+         "1qb4k7pm8w86d2p9q2r4n63iyi34wdib5x9rsjx4vhcxrnzyyygm"))))
     (properties `((upstream-name . "RUVSeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8649,14 +8913,14 @@ samples.")
 (define-public r-biocneighbors
   (package
     (name "r-biocneighbors")
-    (version "1.14.0")
+    (version "1.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocNeighbors" version))
        (sha256
         (base32
-         "1a43hzmcpxviqa9723hkafr6gm358amfpqj9d56imclkkfkdz95x"))))
+         "09f00rf5gwwlxxaycsciq4l53gjg5kjayx8xzhns2yf1fv297j9p"))))
     (properties `((upstream-name . "BiocNeighbors")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8677,14 +8941,14 @@ achieved for all methods using the BiocParallel framework.")
 (define-public r-scaledmatrix
   (package
     (name "r-scaledmatrix")
-    (version "1.4.1")
+    (version "1.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ScaledMatrix" version))
        (sha256
         (base32
-         "05gxr41nb1jqhv357rfha4062kszvrmkr36mhkjsf7kgnzf0p8hz"))))
+         "0lxr6z9zdrgvm06inc1d8gl2agqmbjvgs8f5ryn5x68hqlnchnl1"))))
     (properties `((upstream-name . "ScaledMatrix")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8703,14 +8967,14 @@ multiplication.")
 (define-public r-treeio
   (package
     (name "r-treeio")
-    (version "1.20.2")
+    (version "1.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "treeio" version))
        (sha256
         (base32
-         "1jymbyl82n88ckw0nkbj72rvlxbk5m7xmcmq3fyi885z7aasc0x1"))))
+         "1xl8497ya79hlp3v3fihnz9grwni29v6860i273lrpcljv8868l9"))))
     (properties `((upstream-name . "treeio")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8732,22 +8996,56 @@ heterogeneous associated data to a single tree file and can be served as a
 platform for merging tree with associated data and converting file formats.")
     (license license:artistic2.0)))
 
+(define-public r-treesummarizedexperiment
+  (package
+    (name "r-treesummarizedexperiment")
+    (version "2.6.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "TreeSummarizedExperiment" version))
+              (sha256
+               (base32
+                "136zgpn1l059i64gj6iappr6nz42z4wbxlg3zpc5npwkqrz3val2"))))
+    (properties `((upstream-name . "TreeSummarizedExperiment")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-ape
+           r-biocgenerics
+           r-biocparallel
+           r-biostrings
+           r-dplyr
+           r-iranges
+           r-rlang
+           r-s4vectors
+           r-singlecellexperiment
+           r-summarizedexperiment
+           r-treeio))
+    (native-inputs (list r-knitr))
+    (home-page "https://bioconductor.org/packages/TreeSummarizedExperiment")
+    (synopsis "S4 class for data with tree structures")
+    (description
+     "@code{TreeSummarizedExperiment} extends @code{SingleCellExperiment} to
+include hierarchical information on the rows or columns of the rectangular
+data.")
+    (license license:gpl2+)))
+
 (define-public r-ggtree
   (package
     (name "r-ggtree")
-    (version "3.4.4")
+    (version "3.6.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ggtree" version))
        (sha256
         (base32
-         "0h1qlhn4rj7jgd9vrja7lykaglyfvnzwkghvsqj1mvp4niwli7y5"))))
+         "177nq6arhxp0x6zsf2c6cn3xxwfk65dihbpni6mb9ifgnmfqdjmx"))))
     (properties `((upstream-name . "ggtree")))
     (build-system r-build-system)
     (propagated-inputs
      (list r-ape
            r-aplot
+           r-cli
            r-dplyr
            r-ggfun
            r-ggplot2
@@ -8772,14 +9070,14 @@ data.")
 (define-public r-metapod
   (package
     (name "r-metapod")
-    (version "1.4.0")
+    (version "1.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "metapod" version))
        (sha256
         (base32
-         "19g9c08alg4qqr710si465wlb5dy759m5d8wn91zwj24077dds7b"))))
+         "06ala1qz9bfq7nnj92m0c5r85kk7h4zrljjh0hgrap5sjlsm09bb"))))
     (properties `((upstream-name . "metapod")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8801,14 +9099,14 @@ missing values and weighting where appropriate.")
 (define-public r-biocsingular
   (package
     (name "r-biocsingular")
-    (version "1.12.0")
+    (version "1.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocSingular" version))
        (sha256
         (base32
-         "1sraycnn0jahpi8kni1y8ik00ga89fvwqjmbr8388968q22mvm3x"))))
+         "041izymcifvi0pa97fh5000bwlyl0mdk9003i5bbvlld6mbbv2kk"))))
     (properties `((upstream-name . "BiocSingular")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8836,14 +9134,14 @@ possible, parallelization is achieved using the BiocParallel framework.")
 (define-public r-destiny
   (package
     (name "r-destiny")
-    (version "3.10.0")
+    (version "3.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "destiny" version))
        (sha256
         (base32
-         "1c85ky5ggdsi0ab1l4ipl85gc1kj1zv3wp08qrvslax3z0yw0ljy"))))
+         "0rgd723azjrdxv441k96vircqb18w31q0ljhksbdrvcp9qb85r6i"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
@@ -8880,14 +9178,14 @@ maps.")
 (define-public r-savr
   (package
     (name "r-savr")
-    (version "1.34.0")
+    (version "1.36.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "savR" version))
        (sha256
         (base32
-         "04zlf3lyr6vnpj80m6fd2is2f7302sxwih8nzzjnc4ss972jid2k"))))
+         "1b7kjgj2r6lgkdnrq91wcwvwb5an0gfdsbyp7j0pvn2byfm4lply"))))
     (properties `((upstream-name . "savR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8902,14 +9200,14 @@ Viewer (SAV) files, access data, and generate QC plots.")
 (define-public r-chipexoqual
   (package
     (name "r-chipexoqual")
-    (version "1.20.0")
+    (version "1.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ChIPexoQual" version))
        (sha256
         (base32
-         "1r4s8awvwwj1g33jpnzfxji23mfy0chkhi14i0ml5sh090xijpaz"))))
+         "0k4vbdwpp7z06fzjgqnmrx2yllayc0z2baj26bh4vji5vb48k9ik"))))
     (properties `((upstream-name . "ChIPexoQual")))
     (build-system r-build-system)
     (propagated-inputs
@@ -8942,13 +9240,13 @@ sequencing data.")
 (define-public r-copynumber
   (package
     (name "r-copynumber")
-    (version "1.36.0")
+    (version "1.38.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "copynumber" version))
               (sha256
                (base32
-                "1gr8q9ri49x8qlmbsi6k6wcak1w9v48wr1qy7axc86brzx6z6mhd"))))
+                "1a664bllaq9pbb5cpd01j919qirylvnm8qd49lwlz89jvqjdri19"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-s4vectors r-iranges r-genomicranges r-biocgenerics))
@@ -8962,14 +9260,14 @@ penalized least squares regression method.")
 (define-public r-dnacopy
   (package
     (name "r-dnacopy")
-    (version "1.70.0")
+    (version "1.72.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DNAcopy" version))
        (sha256
         (base32
-         "10bh4p8nbl84rfngsm3bi9w542m159kff95f8c2hvjcxv5yw7iwc"))))
+         "0z2hl68f5f6d2w6gbhax4531g3zbgiihj99h32sa44hp29al38ld"))))
     (properties `((upstream-name . "DNAcopy")))
     (build-system r-build-system)
     (native-inputs (list gfortran))
@@ -9060,14 +9358,14 @@ and regression inferences from RNA-sequencing data.")
 (define-public r-ebseq
   (package
     (name "r-ebseq")
-    (version "1.36.0")
+    (version "1.38.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "EBSeq" version))
        (sha256
         (base32
-         "192xl9fwsh04w563yk33mfl303d1kqby2ssbqkckqsdr4jb7d57y"))))
+         "1gh1cyb76gv2h0knh780648gsbgpn76adfj6x3pjzily5m5bmin0"))))
     (properties `((upstream-name . "EBSeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9082,13 +9380,13 @@ gene and isoform level using RNA-seq data")
 (define-public r-karyoploter
   (package
     (name "r-karyoploter")
-    (version "1.22.0")
+    (version "1.24.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "karyoploteR" version))
               (sha256
                (base32
-                "0hawq9wi3ikvlcdgnjfy5fiiwfq22zwx1p8xf5h4bpypp96pknsk"))))
+                "1dcxq3651903wwzr7bww8c4wd8h5h7rklnqfgklqpss0psx59d2w"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi
@@ -9120,14 +9418,14 @@ coordinates.")
 (define-public r-lpsymphony
   (package
     (name "r-lpsymphony")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "lpsymphony" version))
        (sha256
         (base32
-         "0kc708ss5byzw8qh439mb4nq6hsfmz73gfamiznw3lv352brd33g"))))
+         "0ryl48zxscb35s1gizyspxg48dlqg1j51h9iw2flq16y7y63ppzi"))))
     (build-system r-build-system)
     (arguments
      (list
@@ -9159,14 +9457,14 @@ to install interface to SYMPHONY.")
 (define-public r-ihw
   (package
     (name "r-ihw")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "IHW" version))
        (sha256
         (base32
-         "1gsfy75dz7xh16z844llcmjnp0a0ridszmrbbv2bdaa43na5msmf"))))
+         "04vbf42bzqydf5mi4mqmcyh0xdx4phs4cjhsm6fimhmjhxm8jyry"))))
     (properties `((upstream-name . "IHW")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9188,14 +9486,14 @@ independent of the p-value under the null hypothesis.")
 (define-public r-icobra
   (package
     (name "r-icobra")
-    (version "1.24.1")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "iCOBRA" version))
        (sha256
         (base32
-         "1gvra5bgsf6lvs4f2md3xx7xxsx4j8079c2nr8vz9lvy2sfyl6s9"))))
+         "0mh7arn5rv26picz05ywil5ynras91xv6diwh47s9ip75vp9s3cy"))))
     (properties `((upstream-name . "iCOBRA")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9225,14 +9523,14 @@ interactive exploration of results.")
 (define-public r-residualmatrix
   (package
     (name "r-residualmatrix")
-    (version "1.6.1")
+    (version "1.8.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ResidualMatrix" version))
        (sha256
         (base32
-         "1530706c7b53h9m8smgnaj63rgdbm3hd09n7jwy6zc0y6qcffckd"))))
+         "0zqifr1zhsfhrkjlp0ajqiqc9f96yz8zr13yhl19lvw30pwg9rj9"))))
     (properties
      `((upstream-name . "ResidualMatrix")))
     (build-system r-build-system)
@@ -9254,14 +9552,14 @@ multiplication and calculation of row/column sums or means.")
 (define-public r-batchelor
   (package
     (name "r-batchelor")
-    (version "1.12.3")
+    (version "1.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "batchelor" version))
        (sha256
         (base32
-         "00ix3hvhgalxg63qnynv2waa273jk336lg47k72qwxfzimsxfjxc"))))
+         "1cdpq8zfn718qmsqjp79siddh3kzag4a90p276v261xbjvrxavjv"))))
     (properties `((upstream-name . "batchelor")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9297,14 +9595,14 @@ the numbers of cells across batches.")
 (define-public r-mast
   (package
     (name "r-mast")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MAST" version))
        (sha256
         (base32
-         "1kmrqxcfzzcs8l33n9qn0vahc6wxq6ks3cjx95vg96maf2qzhzzi"))))
+         "133ijkw5sd0gl38dfr7qfqvvp2df7lg6j8vkvy54zlpamkg6l2x1"))))
     (properties `((upstream-name . "MAST")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9332,14 +9630,14 @@ single cell assay data.")
 (define-public r-monocle
   (package
     (name "r-monocle")
-    (version "2.24.1")
+    (version "2.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "monocle" version))
        (sha256
         (base32
-         "11g1wx0f1yzhg3x1aa3d5l7pqlzxj16s0gha21skxkgld8k2x8xn"))))
+         "1d3xgh9xgqa28bgyd06zkjmg75lq7hdah3d140l1bqq2ii1bv62g"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
@@ -9517,14 +9815,14 @@ user-defined and/or data-driven sets of hypotheses.")
 (define-public r-noiseq
   (package
     (name "r-noiseq")
-    (version "2.40.0")
+    (version "2.42.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "NOISeq" version))
        (sha256
         (base32
-         "0ah6adlhv4254jkssinn2ik8n811hd1nw85bnzqk2kwhl49nrk27"))))
+         "1j0yafl5r1vsn99zkhvaz2mrwv37l4p8ldgiq09d9hxpjq9ls7i2"))))
     (properties `((upstream-name . "NOISeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9543,14 +9841,14 @@ assumptions.")
 (define-public r-scdd
   (package
     (name "r-scdd")
-    (version "1.20.0")
+    (version "1.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "scDD" version))
        (sha256
         (base32
-         "0bjww338z5qf2g97kbh85h9kpagjr59ff9f4alm33h16xz5mb7k0"))))
+         "0kmnmlzww2xfd04lp9nsh0wkigab9ipgqlsn2jrd77fizpd0kvwg"))))
     (properties `((upstream-name . "scDD")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9581,14 +9879,14 @@ distributions.")
 (define-public r-scone
   (package
     (name "r-scone")
-    (version "1.20.0")
+    (version "1.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "scone" version))
        (sha256
         (base32
-         "05id34n6min03ha1chg5mrvx399qm2mby9kxkaz5w8fbidp97851"))))
+         "0pg09r28xqjlvb6nbswglnmwi05q63fag6rp3sw41g6z8gm5wap7"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-aroma-light
@@ -9625,14 +9923,14 @@ high-throughput analyses.")
 (define-public r-geoquery
   (package
     (name "r-geoquery")
-    (version "2.64.2")
+    (version "2.66.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GEOquery" version))
        (sha256
         (base32
-         "1cvkvq2haz831qi8w0gd3ayvxfxsl0z5klhki4gkfi9xqdv1gi9x"))))
+         "0ck2aml1kxdahwcszi3j7hcikwi8fdnzphlrsn3h2q4dkk5x00kn"))))
     (properties `((upstream-name . "GEOquery")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9660,14 +9958,14 @@ the bridge between GEO and BioConductor.")
 (define-public r-illuminaio
   (package
     (name "r-illuminaio")
-    (version "0.38.0")
+    (version "0.40.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "illuminaio" version))
        (sha256
         (base32
-         "1xk057a9w4ps8xi8jyw8imkjcicfmzns8g92grn4af7yiip68h62"))))
+         "1cw526mbhh0czkwk99qnr6hfwi4k4xi2bm5p14kw9sr00if59x12"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-base64))
@@ -9681,14 +9979,14 @@ files, including IDAT.")
 (define-public r-siggenes
   (package
     (name "r-siggenes")
-    (version "1.70.0")
+    (version "1.72.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "siggenes" version))
        (sha256
         (base32
-         "0amjqm2c8p1vjzx109p7n81wbsbx8rljwn6mbkl7dpi834im9d7l"))))
+         "0gis34s56y4xa61a9gywjwgd6525ywasa6r4xxhj3rshh1dz5jkv"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase r-multtest r-scrime))
@@ -9705,14 +10003,14 @@ Bayes Analyses of Microarrays} (EBAM).")
 (define-public r-bumphunter
   (package
     (name "r-bumphunter")
-    (version "1.38.0")
+    (version "1.40.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "bumphunter" version))
        (sha256
         (base32
-         "0k92ps9chqsimbc7vsr8swg679zfv8nfn5zahbqq4nknhhy7hwxw"))))
+         "0jwbhd2fhm1w5slwhz8krnw835a8qb4akm3n3pv867bvi0xnp3g2"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi
@@ -9736,16 +10034,64 @@ to identify differentially methylated regions in epigenetic epidemiology
 studies.")
     (license license:artistic2.0)))
 
+(define-public r-mia
+  (package
+    (name "r-mia")
+    (version "1.6.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "mia" version))
+              (sha256
+               (base32
+                "0yz88ggv6d5rccdwzixwg9y1bc4xysazlmv1ph88wxs8r6fcmync"))))
+    (properties `((upstream-name . "mia")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-ape
+           r-biocgenerics
+           r-biocparallel
+           r-biostrings
+           r-decipher
+           r-decontam
+           r-delayedarray
+           r-delayedmatrixstats
+           r-dirichletmultinomial
+           r-dplyr
+           r-iranges
+           r-mass
+           r-multiassayexperiment
+           r-rlang
+           r-s4vectors
+           r-scater
+           r-scuttle
+           r-singlecellexperiment
+           r-summarizedexperiment
+           r-tibble
+           r-tidyr
+           r-treesummarizedexperiment
+           r-vegan))
+    (native-inputs (list r-knitr))
+    (home-page "https://github.com/microbiome/mia")
+    (synopsis "Microbiome analysis")
+    (description
+     "The mia package implements tools for microbiome analysis based on the
+@code{SummarizedExperiment}, @code{SingleCellExperiment} and
+@code{TreeSummarizedExperiment} infrastructure.  Data wrangling and analysis
+in the context of taxonomic data is the main scope.  Additional functions for
+common task are implemented such as community indices calculation and
+summarization.")
+    (license license:artistic2.0)))
+
 (define-public r-microbiome
   (package
     (name "r-microbiome")
-    (version "1.18.0")
+    (version "1.20.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "microbiome" version))
               (sha256
                (base32
-                "1z9arkjp5xszlg07mzb4p163i74jfbd9p4gbwv5syivnpl040k12"))))
+                "1j3lrrz6yxfzsr037c0bbdhrs0ll7jg0mpcvk3iqdryi5rysnx0x"))))
     (properties `((upstream-name . "microbiome")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9776,13 +10122,13 @@ standardization of the analyses and the development of best practices.")
 (define-public r-milor
   (package
     (name "r-milor")
-    (version "1.4.0")
+    (version "1.6.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "miloR" version))
               (sha256
                (base32
-                "1jz9p3grnczx0bpdw6j64x21in8zgm3qy19hmm296har2rx9m5zs"))))
+                "07p9rs1jmgxqaahjbrnvvs94c142n2qfw8ip3qqkr6mhzwr19ly3"))))
     (properties `((upstream-name . "miloR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -9824,14 +10170,14 @@ model.")
 (define-public r-minfi
   (package
     (name "r-minfi")
-    (version "1.42.0")
+    (version "1.44.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "minfi" version))
        (sha256
         (base32
-         "0255z7w5i5k01w8wn7jkb37h3q7m7vg0szqgk76h330yydnmkrq6"))))
+         "15989zilgy2j4k4nw046qg8wli7ynjh2b1yzfv7cwgn87mp618lc"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-beanplot
@@ -9875,14 +10221,14 @@ methylation arrays.")
 (define-public r-methylumi
   (package
     (name "r-methylumi")
-    (version "2.42.0")
+    (version "2.44.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "methylumi" version))
        (sha256
         (base32
-         "0klkinq55lfj1d4z8gkrv98849079x1l5gd15habw7jq9xxvhjww"))))
+         "07kfyv3kkayzh0akxfl3p9gckw8qiplkxbyxw8npc7cb03ihgmc4"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotate
@@ -9922,14 +10268,14 @@ and Infinium HD arrays are also included.")
 (define-public r-lumi
   (package
     (name "r-lumi")
-    (version "2.48.0")
+    (version "2.50.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "lumi" version))
        (sha256
         (base32
-         "06zmll5j1yymsm3byarhllrz4q1w5mzv267a9g6visn73wan8y9d"))))
+         "1091458is69dxnjrcd11czqy55c68sdnkrmpvlm6hw2cbghs2bjq"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-affy
@@ -9961,14 +10307,14 @@ especially Illumina Infinium methylation microarrays.")
 (define-public r-linnorm
   (package
     (name "r-linnorm")
-    (version "2.20.0")
+    (version "2.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Linnorm" version))
        (sha256
         (base32
-         "1002lllgns5klv3q2wsikkbypa2bafpka7a8mri0y5bfxncfr2zb"))))
+         "0ndhvdd9gkqyayxqgj5320sgj15di7ji945lpdi3rj5lwldh7na0"))))
     (properties `((upstream-name . "Linnorm")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10022,14 +10368,14 @@ evaluation of DEG analysis methods.")
 (define-public r-ioniser
   (package
     (name "r-ioniser")
-    (version "2.20.0")
+    (version "2.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "IONiseR" version))
        (sha256
         (base32
-         "0cgx1dcfh617l9vr4r3ky8w7f0snl0vpavfd9n1h5n68p0p42dwi"))))
+         "1xkxqavhcw22lhij87cpd5ps1ldkzzi0pp93d38pxbbhj15gc3d3"))))
     (properties `((upstream-name . "IONiseR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10118,13 +10464,13 @@ published results; and a routine for graphical display.")
 (define-public r-tradeseq
   (package
    (name "r-tradeseq")
-   (version "1.10.0")
+   (version "1.12.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "tradeSeq" version))
             (sha256
              (base32
-              "0v9nqxrwa69qhmyaicn2vvs8haha4kzs93iqim306331vadp9qm0"))))
+              "0wkbjhwqk094nd5h6sl2nw5jp5vmkh9why635l8qkqmxa2jm3gh0"))))
    (build-system r-build-system)
    (propagated-inputs
     (list r-biobase
@@ -10187,14 +10533,14 @@ peak definition in combination with known profile characteristics.")
 (define-public r-varianttools
   (package
     (name "r-varianttools")
-    (version "1.38.0")
+    (version "1.40.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "VariantTools" version))
        (sha256
         (base32
-         "18nxcamfgnw4n2ab0czxglw0sqc9wzdqzpjv43lcyyal23lzzsix"))))
+         "181igcmlyx3ddmhml9wqcgw6ffdrqpmg4imd6ipf68c90agdgaz0"))))
     (properties `((upstream-name . "VariantTools")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10227,14 +10573,14 @@ gmapR.")
 (define-public r-heatplus
   (package
     (name "r-heatplus")
-    (version "3.4.0")
+    (version "3.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Heatplus" version))
        (sha256
         (base32
-         "0b1mzxysmrqinp93p587apna8p0llmawblwj93icydqxxm2jkhb1"))))
+         "0zbjw9f616dz1fpp6q6whbmlrf2gypq8pp9i66c376cs2aifp1si"))))
     (properties `((upstream-name . "Heatplus")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10252,14 +10598,14 @@ information about samples and features can be added to the plot.")
 (define-public r-gosemsim
   (package
     (name "r-gosemsim")
-    (version "2.22.0")
+    (version "2.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GOSemSim" version))
        (sha256
         (base32
-         "1hp15pzd0m0g9f8kglyfsgjqxnvxcmm9022xnsrkzfvmj2yw14vd"))))
+         "14wc7qgk1psknld05246cn0nqxpbjprax7j75h5yyd0w7hjyly2s"))))
     (properties `((upstream-name . "GOSemSim")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10279,14 +10625,14 @@ sets of GO terms, gene products and gene clusters.")
 (define-public r-anota
   (package
     (name "r-anota")
-    (version "1.44.0")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "anota" version))
        (sha256
         (base32
-         "1x75r5znl8jllqsgzpxsqj62ch11bpwhmyzmbjmb8sz8f8ww923c"))))
+         "1a9xgcp48zjql6an3kiv8li4saw10k1dl7qzyyw84xvx856ilv97"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-multtest r-qvalue))
@@ -10309,14 +10655,14 @@ the data set is suitable for such analysis.")
 (define-public r-sigpathway
   (package
     (name "r-sigpathway")
-    (version "1.64.0")
+    (version "1.66.0")
     (source
       (origin
         (method url-fetch)
         (uri (bioconductor-uri "sigPathway" version))
         (sha256
           (base32
-            "1c2kwhbxgf66az7ssm2mab9n5x59zy4kxq8vblz5r9636xqaysif"))))
+            "0vb6v61ak8z3hx7d65lr1hrxk89n36j0zi3x0pp828khdyh3zvag"))))
     (properties `((upstream-name . "sigPathway")))
     (build-system r-build-system)
     (home-page "https://www.pnas.org/cgi/doi/10.1073/pnas.0506577102")
@@ -10331,13 +10677,13 @@ phenotype of interest.")
 (define-public r-fcscan
   (package
     (name "r-fcscan")
-    (version "1.10.0")
+    (version "1.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "fcScan" version))
        (sha256
-        (base32 "0yv7ifw0xxx1v9z8dxszv0cb72q3frd74dyxfbvrcs6x9y9v3jzp"))))
+        (base32 "0z83ncjxw9x8nvc6pncrvpf6lmamvgrv56j96s1f0x9jydk18chy"))))
     (properties `((upstream-name . "fcScan")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10364,22 +10710,22 @@ presence of additional sites within the allowed window size.")
 (define-public r-fgsea
   (package
     (name "r-fgsea")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "fgsea" version))
        (sha256
         (base32
-         "0innyggai6l4fpl4qrblzdc52vqw9jaszmip0yr1lv7rzwyl6mpg"))))
+         "1frl5mchbrgqyxxdlw76qqq5i8vv2fdmy8xl8h8c8cvvmlz393qk"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-bh
            r-biocparallel
+           r-cowplot
            r-data-table
            r-fastmatch
            r-ggplot2
-           r-gridextra
            r-matrix
            r-rcpp))
     (native-inputs
@@ -10396,23 +10742,23 @@ to multiple hypothesis correction.")
 (define-public r-dose
   (package
     (name "r-dose")
-    (version "3.22.1")
+    (version "3.24.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DOSE" version))
        (sha256
         (base32
-         "1mch26kddrhhzgi4bssnyy7bvdhprrncmvxl6zn1cq7g07p5765i"))))
+         "0scp6sgb1iwwfh7gdak4dxf1hb870745km9nc9hga8pnsnqi5v3g"))))
     (properties `((upstream-name . "DOSE")))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi
            r-biocparallel
-           r-do-db
            r-fgsea
            r-ggplot2
            r-gosemsim
+           r-hdo-db
            r-qvalue
            r-reshape2))
     (native-inputs
@@ -10431,20 +10777,21 @@ data.")
 (define-public r-enrichplot
   (package
     (name "r-enrichplot")
-    (version "1.16.2")
+    (version "1.18.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "enrichplot" version))
        (sha256
         (base32
-         "0qh7bci3rn6y2fl45izrdb62jcm6j0zxxg4pyp4mvvgjvka5lnss"))))
+         "1x84wlkqisq1x2zniy4mp02zlsp4v85kxbflalmq0pixlkagq0vr"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-aplot
            r-dose
            r-ggplot2
            r-ggraph
+           r-ggnewscale
            r-ggtree
            r-gosemsim
            r-igraph
@@ -10453,6 +10800,7 @@ data.")
            r-purrr
            r-rcolorbrewer
            r-reshape2
+           r-rlang
            r-scatterpie
            r-shadowtext
            r-yulab-utils))
@@ -10469,14 +10817,14 @@ All the visualization methods are developed based on ggplot2 graphics.")
 (define-public r-clusterprofiler
   (package
     (name "r-clusterprofiler")
-    (version "4.4.4")
+    (version "4.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "clusterProfiler" version))
        (sha256
         (base32
-         "0k5jhry0j6wa7779n3hrw4ld4bvyahpgpbwi2a0g704m3dd3mqp5"))))
+         "0fm2cz2464xh075p4yl6bha9m6didc41ng4a3flkw1f1cvvpi4g0"))))
     (properties
      `((upstream-name . "clusterProfiler")))
     (build-system r-build-system)
@@ -10488,6 +10836,7 @@ All the visualization methods are developed based on ggplot2 graphics.")
            r-enrichplot
            r-go-db
            r-gosemsim
+           r-gson
            r-magrittr
            r-plyr
            r-qvalue
@@ -10506,13 +10855,13 @@ profiles (GO and KEGG) of gene and gene clusters.")
 (define-public r-clusterexperiment
   (package
     (name "r-clusterexperiment")
-    (version "2.16.0")
+    (version "2.18.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "clusterExperiment" version))
               (sha256
                (base32
-                "1xd2kxmdg51hhj0zvz7pxmpdvb1sya7prsf9ny2wj2y8ivrqgn4f"))))
+                "04kdiwz8qzr7cr1an1c7a684wqv9pkca0iaym5f069pdjhqvvq0a"))))
     (build-system r-build-system)
     (native-inputs
      (list r-knitr))
@@ -10552,14 +10901,14 @@ expression data sets.")
 (define-public r-mlinterfaces
   (package
     (name "r-mlinterfaces")
-    (version "1.76.0")
+    (version "1.78.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MLInterfaces" version))
        (sha256
         (base32
-         "179d19kxjipfkc40z15337x1vzqd7vz3gbmr2lw5w7x9l857ngs5"))))
+         "0xnaghm65ydk01gzx5g38jyq7vfdw206c2w59k0qg8lhy9fqky9x"))))
     (properties `((upstream-name . "MLInterfaces")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10582,6 +10931,7 @@ expression data sets.")
            r-rpart
            r-sfsmisc
            r-shiny
+           r-summarizedexperiment
            r-threejs))
     (home-page "https://bioconductor.org/packages/MLInterfaces/")
     (synopsis "Interfaces to R machine learning procedures")
@@ -10594,14 +10944,14 @@ data in R and Bioconductor containers.")
 (define-public r-annaffy
   (package
     (name "r-annaffy")
-    (version "1.68.0")
+    (version "1.70.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "annaffy" version))
        (sha256
         (base32
-         "1fbqknwbl4534h66xrhcryg9pavm9fkja47gqbsxf8bd5yhk5mgq"))))
+         "0qxihlhx7ijspvgzdp8zxzrc44y9pwkygvsllh4v47p85ham49fg"))))
     (build-system r-build-system)
     (arguments
      `(#:phases
@@ -10626,14 +10976,14 @@ It allows searching of biological metadata using various criteria.")
 (define-public r-a4core
   (package
     (name "r-a4core")
-    (version "1.44.0")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "a4Core" version))
        (sha256
         (base32
-         "1ky1lphq6bqxj6h12pg06cvs451fziqam8gd56wmpk6r5pbg4390"))))
+         "0plgfzsvg220v6k6p0g7izsfw2lj78331lqyvz0p9vd91ynwp41k"))))
     (properties `((upstream-name . "a4Core")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10650,14 +11000,14 @@ arrays.")
 (define-public r-a4classif
   (package
     (name "r-a4classif")
-    (version "1.44.0")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "a4Classif" version))
        (sha256
         (base32
-         "1v61vgpqrf7bhk44n2gkxb8dm5d0rr8c9rd6fdcjs50nhij0lbiw"))))
+         "0lirj0qzzrm996g8yh30x61cg1qkh436qd8xzgv3y3y3n5jj5d3w"))))
     (properties `((upstream-name . "a4Classif")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10680,14 +11030,14 @@ Affymetrix arrays.")
 (define-public r-a4preproc
   (package
     (name "r-a4preproc")
-    (version "1.44.0")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "a4Preproc" version))
        (sha256
         (base32
-         "098yzy7x5536bj76iavismdsdn7x6x07aw0j3knj6i9www9y8yz9"))))
+         "00xs1vayl8v6in79iv7lwbn52yyyq4lv6k3k727g7il8x17mi8i0"))))
     (properties `((upstream-name . "a4Preproc")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10704,14 +11054,14 @@ is used for preprocessing the arrays.")
 (define-public r-a4reporting
   (package
     (name "r-a4reporting")
-    (version "1.44.0")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "a4Reporting" version))
        (sha256
         (base32
-         "03sypayh187gqc6hykkqr1g0vb3zxc2c3xyp00jfbn12b35acnb0"))))
+         "09q8ng5kp47bqpj7m2y2112fkjxcnhzxk9v80hqksm8h1df46riv"))))
     (properties `((upstream-name . "a4Reporting")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10728,14 +11078,14 @@ provides reporting features.")
 (define-public r-a4base
   (package
     (name "r-a4base")
-    (version "1.44.0")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "a4Base" version))
        (sha256
         (base32
-         "15zqirz16gpks9f5d3d76h85b936za2jih74vfr55l5arqrrvvsn"))))
+         "14diri7gswd6h5p3bdhh20fy7i54d270mq985qcdvdyhx4kpw6g6"))))
     (properties `((upstream-name . "a4Base")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10759,14 +11109,14 @@ Affymetrix arrays.")
 (define-public r-a4
   (package
     (name "r-a4")
-    (version "1.44.0")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "a4" version))
        (sha256
         (base32
-         "1zs8fs6mdd7fhsmx4k824mid0jk400cm6dwfhl8z5lg85y8y2n0r"))))
+         "1sis4hwrxyn2x96yysz82gffl2kkj68ry945y15zwikwk80s31hb"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-a4base r-a4classif r-a4core r-a4preproc r-a4reporting))
@@ -10780,14 +11130,14 @@ Affymetrix arrays.")
 (define-public r-abseqr
   (package
     (name "r-abseqr")
-    (version "1.14.0")
+    (version "1.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "abseqR" version))
        (sha256
         (base32
-         "0jh3rj6ag07vpw6fymqm6m4jkrm9mgf50zkjncahxdf52mna8a9b"))))
+         "1z5an4vsm55a0qr46qmp8562vc3xdam5f3840r8hcdnn5dvzw414"))))
     (properties `((upstream-name . "abseqR")))
     (build-system r-build-system)
     (inputs
@@ -10828,14 +11178,14 @@ further downstream analysis on its output.")
 (define-public r-bacon
   (package
     (name "r-bacon")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "bacon" version))
        (sha256
         (base32
-         "1zvcxdj3r892898ik5gq3jdbfig1438qws4bwd465ik8vi7g39v8"))))
+         "1v5kvvbc5fwvs84d2aq6gq6f6z0l68n7626gcnc8mh3sc27lxz53"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biocparallel r-ellipse r-ggplot2))
@@ -10853,14 +11203,14 @@ fitting a three-component normal mixture on z-scores.")
 (define-public r-rgadem
   (package
     (name "r-rgadem")
-    (version "2.44.1")
+    (version "2.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "rGADEM" version))
        (sha256
         (base32
-         "052z9iavnmkaz9jzz7ycpb8z7qqq3s5k6a04icrwl00wff7zqa2q"))))
+         "070i3jdq8b5w7k42xw2fc3vcmv312i19fa1am4fbk3g3ssnm61p3"))))
     (properties `((upstream-name . "rGADEM")))
     (build-system r-build-system)
     (propagated-inputs
@@ -10907,12 +11257,12 @@ distributions, modules and filter motifs.")
 (define-public r-motifdb
   (package
    (name "r-motifdb")
-   (version "1.38.0")
+   (version "1.40.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "MotifDb" version))
             (sha256
-             (base32 "1cyfz0l0yvdii3idaiq5w39yzxlzfpifa4v5pv7hdjfjj83a8rbi"))))
+             (base32 "122ifxmbi0v3192cd9chq265i3dyw3hzwsndq3w97f4d68vll7gl"))))
    (properties `((upstream-name . "MotifDb")))
    (build-system r-build-system)
    (propagated-inputs
@@ -10934,12 +11284,12 @@ frequency matrices from nine public sources, for multiple organisms.")
 (define-public r-motifbreakr
   (package
    (name "r-motifbreakr")
-   (version "2.10.0")
+   (version "2.12.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "motifbreakR" version))
             (sha256
-             (base32 "0sad73jjx52qzp1fmygp6xqvaxwl5szi69f00f94i1pdyq70qhlg"))))
+             (base32 "0lq79as9gb48hf3v2xj895s0nsjr37fqah4p405kdybzry56gvrq"))))
    (properties `((upstream-name . "motifbreakR")))
    (build-system r-build-system)
    (propagated-inputs
@@ -10984,14 +11334,14 @@ Bioconductor.")
 (define-public r-motifstack
   (package
     (name "r-motifstack")
-    (version "1.40.0")
+    (version "1.42.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "motifStack" version))
        (sha256
         (base32
-         "0d2ihx73chczbv6f91n04qb372plrdv7k4qws8shyw1fmvb1rq0z"))))
+         "18gfx5dq83s2ny39a7cgg4r3b05gg9l0kfg83brwrm1cby08jdhm"))))
     (properties `((upstream-name . "motifStack")))
     (build-system r-build-system)
     (propagated-inputs
@@ -11016,14 +11366,14 @@ type and symbol colors.")
 (define-public r-genomicscores
   (package
     (name "r-genomicscores")
-    (version "2.8.2")
+    (version "2.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GenomicScores" version))
        (sha256
         (base32
-         "12rcxw69an1d5q7ar58xy8s871l47imw2nm08j054ivxslx8597j"))))
+         "1sz0gmwc5iam83pxnc702pd5h6nsa46kb0wsqs8ysb1ximbkfh5h"))))
     (properties `((upstream-name . "GenomicScores")))
     (build-system r-build-system)
     (propagated-inputs
@@ -11054,14 +11404,14 @@ position-specific scores within R and Bioconductor.")
 (define-public r-atacseqqc
   (package
     (name "r-atacseqqc")
-    (version "1.20.2")
+    (version "1.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ATACseqQC" version))
        (sha256
         (base32
-         "0jj7n0mcj0gciw0ksazlksgmwzp51a40pwqhf0c7la0cc4bnrkqp"))))
+         "12ggi2dzf8qyzjrxprvk099f61yrabg2d84iqnjxzrn77v6z19b2"))))
     (properties `((upstream-name . "ATACseqQC")))
     (build-system r-build-system)
     (propagated-inputs
@@ -11101,14 +11451,14 @@ footprints.")
 (define-public r-gofuncr
   (package
     (name "r-gofuncr")
-    (version "1.16.0")
+    (version "1.18.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GOfuncR" version))
        (sha256
         (base32
-         "02vdfsjrqp0m06mfbspwkxjyqxfca0w1idgygpi1a9i5m4fqhwpk"))))
+         "0d0xis4nns5icsr16w4ik2d95n3p2h93c47jvlp22crv7f4rlaa5"))))
     (properties `((upstream-name . "GOfuncR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -11206,14 +11556,14 @@ different identifieres using the Biocore Data Team data-packages (e.g.
 (define-public r-annotationtools
   (package
     (name "r-annotationtools")
-    (version "1.70.0")
+    (version "1.72.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "annotationTools" version))
        (sha256
         (base32
-         "122b424zida3j0vqkn8d06sg3jpc3ngsgidr8kgg00n4cjngkc51"))))
+         "1z5vgblhi1kj2n9d4kbqgvwnm48372q0szgjshch8g39dypijvhd"))))
     (properties
      `((upstream-name . "annotationTools")))
     (build-system r-build-system)
@@ -11231,14 +11581,14 @@ text files).")
 (define-public r-allelicimbalance
   (package
     (name "r-allelicimbalance")
-    (version "1.34.0")
+    (version "1.36.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "AllelicImbalance" version))
        (sha256
         (base32
-         "0w4xd0xzkwx7bbhrgqligpahlhg85rginknx520z891r8v0bim2z"))))
+         "0zn8pp4pl5wr957mf6agjpn61f9qpnjx0nbxb5wnbr40672x0263"))))
     (properties
      `((upstream-name . "AllelicImbalance")))
     (build-system r-build-system)
@@ -11274,14 +11624,14 @@ investigation using RNA-seq data.")
 (define-public r-aucell
   (package
     (name "r-aucell")
-    (version "1.18.1")
+    (version "1.20.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "AUCell" version))
        (sha256
         (base32
-         "17wr7dycll0l1gax4w268qw7is163bs51rj6p1qnx1dgc9ibnsgr"))))
+         "0bq729kavqkam2s4dmfzixgznsys61j0lvj5pk3b70gxv44gmpsh"))))
     (properties `((upstream-name . "AUCell")))
     (build-system r-build-system)
     (propagated-inputs
@@ -11314,14 +11664,14 @@ needed.")
 (define-public r-ebimage
   (package
     (name "r-ebimage")
-    (version "4.38.0")
+    (version "4.40.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "EBImage" version))
        (sha256
         (base32
-         "1vcx45bw36k9daw9dywj5bz77jmqk4gjfwsym8ajjnc1jmlq20si"))))
+         "1k6gbivwlai451whq2vr3c0shzs9p4g188jn5waw7973gdzdi00q"))))
     (properties `((upstream-name . "EBImage")))
     (build-system r-build-system)
     (propagated-inputs
@@ -11353,14 +11703,14 @@ visualization with image data.")
 (define-public r-yamss
   (package
     (name "r-yamss")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "yamss" version))
        (sha256
         (base32
-         "1lcfxw73cxvpy3bnq28pxdy5128mpq5xklsa0mzxdjyqc4g55hy8"))))
+         "0bh06mncjrkihz2j29hasbipfl50x7393wshdcnlxrs5rrq73r0n"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biocgenerics
@@ -11386,14 +11736,14 @@ analysis.")
 (define-public r-gtrellis
   (package
     (name "r-gtrellis")
-    (version "1.28.0")
+    (version "1.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "gtrellis" version))
        (sha256
         (base32
-         "1s4xczzv6hz2kyv32xgcq84540w75qr3f644w1s4c3kwxgyq2gff"))))
+         "09f20qam59iwr48g854b7ydbsbqy90mdy83i2i0am4gybv5isgqg"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-circlize r-genomicranges r-getoptlong r-iranges))
@@ -11412,14 +11762,14 @@ genomic categories and to add self-defined graphics in the plot.")
 (define-public r-somaticsignatures
   (package
     (name "r-somaticsignatures")
-    (version "2.32.0")
+    (version "2.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "SomaticSignatures" version))
        (sha256
         (base32
-         "1ydnp54laznzpi08s403kxhnr5nqhvm3iilaxlcdlz0ngxhm6vx6"))))
+         "0xyh4pwwbpa1bmamqdhp84qhjdc2qsxc43xgknjrrja24d06ji2j"))))
     (properties
      `((upstream-name . "SomaticSignatures")))
     (build-system r-build-system)
@@ -11451,14 +11801,14 @@ decomposition algorithms.")
 (define-public r-yapsa
   (package
     (name "r-yapsa")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "YAPSA" version))
        (sha256
         (base32
-         "1klqfif4sadkxw7agywk2ncvcdqsnfb1d6adnacdfdasr8abvhid"))))
+         "17yxzqvyaa423k0rskahlgqxcsi70flgsxniry3f4m8yvmghxxkz"))))
     (properties `((upstream-name . "YAPSA")))
     (build-system r-build-system)
     (propagated-inputs
@@ -11500,14 +11850,14 @@ provided.")
 (define-public r-gcrma
   (package
     (name "r-gcrma")
-    (version "2.68.0")
+    (version "2.70.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "gcrma" version))
        (sha256
         (base32
-         "13a8igr2b02gsa6n3437kb33wg6h7si82fmqi35dzpfzhvx0qf6d"))))
+         "0a3wjwjgjkpmfvgg0b4jc1rkwzsqrjbaziydjfnkll4rw9xcavy1"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-affy
@@ -11582,14 +11932,14 @@ chips with the MAQC reference datasets.")
 (define-public r-quantro
   (package
     (name "r-quantro")
-    (version "1.30.0")
+    (version "1.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "quantro" version))
        (sha256
         (base32
-         "1zfrz7lxyrbf0c8d277npzj1h4six9whkqplvcjmn3li0xj5qng3"))))
+         "0f274wh0w6nyipac05y6s2m2p60vkls5j4fwa5bc419j68h4znnz"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
@@ -11615,14 +11965,14 @@ groups.")
 (define-public r-yarn
   (package
     (name "r-yarn")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "yarn" version))
        (sha256
         (base32
-         "0z5202pqq02fwm8qf1g36004k7sv668s1xacbpr1cvw5sl452lbg"))))
+         "0sqbll7ja0qr8r28dqmydmkvg4ijfm7z8hbrsrz3xxdan70bmd2r"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
@@ -11652,14 +12002,14 @@ large RNA-seq experiments.")
 (define-public r-roar
   (package
     (name "r-roar")
-    (version "1.32.0")
+    (version "1.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "roar" version))
        (sha256
         (base32
-         "0zq1praf5h9294cvmrb06l3chx8v40xw2sfvhlnh1516x9sjkwfc"))))
+         "1bf3ii3zaxkzw5y1wc5c474bq4cgavb67df54czmd3zi1lbhzphd"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biocgenerics
@@ -11720,14 +12070,14 @@ genes.")
 (define-public r-massspecwavelet
   (package
     (name "r-massspecwavelet")
-    (version "1.62.0")
+    (version "1.64.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MassSpecWavelet" version))
        (sha256
         (base32
-         "0g9izdy3f7h1zmsfbq45ahdz0ak5013rp3vxc4ijb1mpqx8ldd39"))))
+         "0l86gwq073nbx973v99b0lr9cz0pb72c4asmgj5w16jykicrnxn9"))))
     (properties
      `((upstream-name . "MassSpecWavelet")))
     (build-system r-build-system)
@@ -11744,14 +12094,14 @@ based on @dfn{Continuous Wavelet Transform} (CWT).")
 (define-public r-xcms
   (package
     (name "r-xcms")
-    (version "3.18.0")
+    (version "3.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "xcms" version))
        (sha256
         (base32
-         "0p2zd2728lj5q8y24gdfvsjijd6zl2i73hrcf017n32jq7vn71xm"))))
+         "1gj0nd90c6ykwn1n7xndzrgfv5dzy0y2lh3bf8120nacccgxl2qx"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
@@ -11785,13 +12135,13 @@ data for high-throughput, untargeted analyte profiling.")
 (define-public r-wppi
   (package
     (name "r-wppi")
-    (version "1.4.0")
+    (version "1.6.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "wppi" version))
               (sha256
                (base32
-                "1008s39bb7sd261cy1vfgdah7bmhfw9qq322fh7g4wvpfw63ii9f"))))
+                "0kc3nkim8fhajhai5bwzwirsg74zbdib3dd7cfr75ddwd8myc913"))))
     (properties `((upstream-name . "wppi")))
     (build-system r-build-system)
     ;; This is necessary because omnipathr attempts to write a configuration
@@ -11826,14 +12176,14 @@ scores and a path search algorithm.")
 (define-public r-wrench
   (package
     (name "r-wrench")
-    (version "1.14.0")
+    (version "1.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Wrench" version))
        (sha256
         (base32
-         "1zx65s4m71wj85s2sq8ip54pq12r4sxfv8b2rxc41gfc5aj0zzca"))))
+         "0n7mvj9jdp8w5w64i49kkqzbrvpv2vzx6y6fb7g2sqp24wqrn39x"))))
     (properties `((upstream-name . "Wrench")))
     (build-system r-build-system)
     (propagated-inputs
@@ -11850,14 +12200,14 @@ that arising from 16s metagenomic surveys.")
 (define-public r-wiggleplotr
   (package
     (name "r-wiggleplotr")
-    (version "1.20.0")
+    (version "1.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "wiggleplotr" version))
        (sha256
         (base32
-         "0s128mm5w8n072k6j0fv1mxnxjpwisjp5lpz8a9z96cnn69bnr0i"))))
+         "1yp9siy4249wkwd0yy5lkwp79xir53f8mihiv4dkir8fscgampl3"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-assertthat
@@ -11884,14 +12234,14 @@ visualization of exonic read coverage.")
 (define-public r-widgettools
   (package
     (name "r-widgettools")
-    (version "1.74.0")
+    (version "1.76.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "widgetTools" version))
        (sha256
         (base32
-         "10w1s5h4za6ibmphvj145ir3lp22qgah2z8fvmipmf8ciq1jf86d"))))
+         "1p93dzf7w9z1ria0f8n32aymam9abxyg50ngnh7s6a8n24mvvjy5"))))
     (properties `((upstream-name . "widgetTools")))
     (build-system r-build-system)
     (home-page "https://bioconductor.org/packages/widgetTools/")
@@ -11905,14 +12255,14 @@ widgets in R.")
 (define-public r-webbioc
   (package
     (name "r-webbioc")
-    (version "1.68.0")
+    (version "1.70.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "webbioc" version))
        (sha256
         (base32
-         "1g3srxsa2fqcn3r4wz4y19fwjmw3vawlcvdw6lbjdnvbgcafq1ah"))))
+         "1mgag0gjavpld4xxlpfafq6fhzjafxgqyf677xrm6ff26z6z1ja2"))))
     (build-system r-build-system)
     (inputs
      (list netpbm perl))
@@ -11937,14 +12287,14 @@ Currently only Affymetrix oligonucleotide analysis is supported.")
 (define-public r-zinbwave
   (package
     (name "r-zinbwave")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "zinbwave" version))
        (sha256
         (base32
-         "0vpz721sciw5b4ypxj5lj8p53gwkpfwlwkn6k3y8i65zg80p1g6i"))))
+         "1356ms5y6fg7ndn8hvs6zsyr0jg6ah7a56qxd2x4xgyjj3xcakbv"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biocparallel
@@ -11970,14 +12320,14 @@ the data.")
 (define-public r-zfpkm
   (package
     (name "r-zfpkm")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "zFPKM" version))
        (sha256
         (base32
-         "1h7g553rgb5mkmmsp8dyqqs9n9x17xmmcg3iijhb54nyrr2j1mji"))))
+         "1wsmv4fld4s7l0qh84ghizq8k388ybdz9hzzis2gn1nn57q1c7wi"))))
     (properties `((upstream-name . "zFPKM")))
     (build-system r-build-system)
     (propagated-inputs
@@ -11995,14 +12345,14 @@ This algorithm is based on the publication by Hart et al., 2013 (Pubmed ID
 (define-public r-rbowtie2
   (package
     (name "r-rbowtie2")
-    (version "2.2.0")
+    (version "2.4.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rbowtie2" version))
        (sha256
         (base32
-         "0dhdx27vrkhd4fak0qb5q9amlcpi97xhf3ry39zk0ifx5zpjynkg"))))
+         "05cczwkhv7kfnhlr0qznk6vdjncaj907895923f8mwx4j4cy5gcz"))))
     (properties `((upstream-name . "Rbowtie2")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12022,14 +12372,14 @@ rapid adapter trimming, identification, and read merging.")
 (define-public r-progeny
   (package
     (name "r-progeny")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "progeny" version))
        (sha256
         (base32
-         "1rhy2l2yf9ndxlvff8756s6n8qyi42nz7a75lgygj5aqqckkj21b"))))
+         "0f5sfi9r9dr6w3xmspsbzby8dpza8x7djif7p2h6l99kwkf68jsb"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
@@ -12054,14 +12404,14 @@ expression\".")
 (define-public r-arrmnormalization
   (package
     (name "r-arrmnormalization")
-    (version "1.36.0")
+    (version "1.38.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ARRmNormalization" version))
        (sha256
         (base32
-         "1pnvw8psbql787m8lrmhd9xbmgkc3dbc70yfds1aggv50dk3yjk1"))))
+         "14mffjsy7cwpa2xf8zdqwdk6mnfj3lf06y8s59ndh531b45nw5wc"))))
     (properties
      `((upstream-name . "ARRmNormalization")))
     (build-system r-build-system)
@@ -12077,14 +12427,14 @@ Infinium HumanMethylation 450k assay.")
 (define-public r-biocfilecache
   (package
     (name "r-biocfilecache")
-    (version "2.4.0")
+    (version "2.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocFileCache" version))
        (sha256
         (base32
-         "1bdbmlixrd8wvs25nmzdksq5hwnsxf8b6ds9qwx01h284vky5vsw"))))
+         "0skrvmkm6ch8gbpdi4wr59zk5vxzxs7cyqvz3jhki9d8w492wylg"))))
     (properties `((upstream-name . "BiocFileCache")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12110,14 +12460,14 @@ and data files used across sessions.")
 (define-public r-iclusterplus
   (package
     (name "r-iclusterplus")
-    (version "1.32.0")
+    (version "1.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "iClusterPlus" version))
        (sha256
         (base32
-         "0xzx3vly3p99zc5a69pra4jjp8d3bdhx7dl1l76w459cs58zy0sm"))))
+         "01bl1gmc1v1b4lh88sdazjvm8pl7383dgzxnhmzpxwz7lkcxi1h2"))))
     (properties `((upstream-name . "iClusterPlus")))
     (build-system r-build-system)
     (native-inputs (list gfortran))
@@ -12140,14 +12490,14 @@ Gaussian distributions.")
 (define-public r-rbowtie
   (package
     (name "r-rbowtie")
-    (version "1.36.0")
+    (version "1.38.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rbowtie" version))
        (sha256
         (base32
-         "1ya1irwshsyy9l1fj51b04nv1ahq7a47ck7q19h2cly6yskc4x1q"))))
+         "1kbpqhidj2bwhp9gxqx2qjaby6fc2dfrnnyjkciswgxckis6h2pc"))))
     (properties `((upstream-name . "Rbowtie")))
     (build-system r-build-system)
     (arguments
@@ -12176,14 +12526,14 @@ alignment tool.")
 (define-public r-sgseq
   (package
     (name "r-sgseq")
-    (version "1.30.0")
+    (version "1.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "SGSeq" version))
        (sha256
         (base32
-         "0hz45367i70wl97silnimicdvs3g41zyf8syc6igz6471wbwkxwp"))))
+         "03ddz0mpgqqb52r7wa46bcr1ybf40126pg0n0n0pv6fnbq0ifwyc"))))
     (properties `((upstream-name . "SGSeq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12219,14 +12569,14 @@ interpretation.")
 (define-public r-rhisat2
   (package
     (name "r-rhisat2")
-    (version "1.12.0")
+    (version "1.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rhisat2" version))
        (sha256
         (base32
-         "0hzair41l47kzykymd169a34pfhb98vrjgkgdf15m17csyz7pnv7"))))
+         "19dc9fadgl55icqc5xv834kigicxxr6cny83247jjbgf5zp16piv"))))
     (properties `((upstream-name . "Rhisat2")))
     (build-system r-build-system)
     (arguments
@@ -12257,14 +12607,14 @@ index.")
 (define-public r-quasr
   (package
     (name "r-quasr")
-    (version "1.36.0")
+    (version "1.38.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "QuasR" version))
        (sha256
         (base32
-         "1m0c0rdakkdn4rr6dh51c6rs40cbxkvz93n6s0m2kc6fqjv9zplf"))))
+         "1pp94368aj5wx0zcnbbm6zrxrfhixmbcdzpj2lka3blvq5j7sncj"))))
     (properties `((upstream-name . "QuasR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12299,14 +12649,14 @@ quantification of genomic regions of interest.")
 (define-public r-rqc
   (package
     (name "r-rqc")
-    (version "1.30.0")
+    (version "1.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rqc" version))
        (sha256
         (base32
-         "11j8m69zdcmpjb3xzr4s8sqmv8aqgl8q7k81gnd09l3nyjzy0h1k"))))
+         "02k64pjd1dlz5sksdbkbii9z4ihf1833ws7wwj81w3757zzabx0x"))))
     (properties `((upstream-name . "Rqc")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12342,14 +12692,14 @@ graphics.")
 (define-public r-birewire
   (package
     (name "r-birewire")
-    (version "3.28.0")
+    (version "3.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiRewire" version))
        (sha256
         (base32
-         "0r3i7n45qgj8wzdsx8wmfk0lc4xbcvxvmfziiqzig7r706q2c2hm"))))
+         "0nr40nm87qzbni3w0cik887csc899jh7j8z82i94v15fc30vfilh"))))
     (properties `((upstream-name . "BiRewire")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12395,14 +12745,14 @@ Markov-Chain-Monte-Carlo is applied to sample the activity states.")
 (define-public r-multidataset
   (package
     (name "r-multidataset")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MultiDataSet" version))
        (sha256
         (base32
-         "0rfs6jkzh1i4mj1pgfk4lwzmcl8pcwizra3q3282x3d8h2g98qnf"))))
+         "1qja5xd42wh8qbcil4hhnmh9zlby2gfglax2qbf5bzg3h6yzpy4g"))))
     (properties `((upstream-name . "MultiDataSet")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12432,19 +12782,21 @@ packages.")
 (define-public r-ropls
   (package
     (name "r-ropls")
-    (version "1.28.2")
+    (version "1.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ropls" version))
        (sha256
         (base32
-         "07gpx15r8c3wljiwxnff2zp7wxbhzz9r7njk8zg8hpy2q5qm3i6c"))))
+         "0vjwci0z83b56q1wi1k00926f0vh3220a44m0zzfxg2cm5j3fwxb"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
+           r-ggplot2
            r-multiassayexperiment
            r-multidataset
+           r-plotly
            r-summarizedexperiment))
     (native-inputs
      (list r-knitr)) ; for vignettes
@@ -12472,14 +12824,14 @@ coefficients).")
 (define-public r-biosigner
   (package
     (name "r-biosigner")
-    (version "1.24.2")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biosigner" version))
        (sha256
         (base32
-         "0vdv2by3qv7y8vzr8qgg7apwwgsa0fhlfrhzns7g3nas7883c89m"))))
+         "11ncmxy4wqdg30w8a6dgcsywyzda49f9al435fz3pfj5rmlbbrlj"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
@@ -12507,14 +12859,14 @@ datasets.")
 (define-public r-annotatr
   (package
     (name "r-annotatr")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "annotatr" version))
        (sha256
         (base32
-         "1fbax9v3d486c8lwf3yfjbf4w7zf53wmdpxk2clwm8ngm7w0pqm0"))))
+         "08f3xikgb0z1j7n8i04yn1dlfj8rxc76nmf5b7i5ljcp0jqiv07n"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi
@@ -12548,14 +12900,14 @@ annotations.")
 (define-public r-rsubread
   (package
     (name "r-rsubread")
-    (version "2.10.5")
+    (version "2.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rsubread" version))
        (sha256
         (base32
-         "0n9qqbkj2lgxkia6kfpfz06wbc1lvw24qyvn88f48zw5nh0rsrs2"))))
+         "0iha7xln7l3mrmka8rcmmlp74f5km9rc88k9nv6bxw0krr03089n"))))
     (properties `((upstream-name . "Rsubread")))
     (build-system r-build-system)
     (inputs (list zlib))
@@ -12600,14 +12952,14 @@ and to both short and long sequence reads.")
 (define-public r-consensusclusterplus
   (package
     (name "r-consensusclusterplus")
-    (version "1.60.0")
+    (version "1.62.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ConsensusClusterPlus" version))
        (sha256
         (base32
-         "1021cix4mr9qsafskw4kk1l3wdzx9pk2gcwjifz6f4zqxss9v07p"))))
+         "15cz3bbl21vzf5xn5xb791sy2yvzir7h4fdqm0a5anhbh8jg0iaq"))))
     (properties
      `((upstream-name . "ConsensusClusterPlus")))
     (build-system r-build-system)
@@ -12666,14 +13018,14 @@ of the analyses while minimizing technical noise.")
 (define-public r-cytolib
   (package
     (name "r-cytolib")
-    (version "2.8.0")
+    (version "2.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "cytolib" version))
        (sha256
         (base32
-         "18b532sicca5l8sn334prrm7g1z1cakiwydccz4i833168pnsjyg"))))
+         "1y06x7z3p938kfvjx6zqab9hh1xzlrlhdxczyprx7lsd34ylz46n"))))
     (properties `((upstream-name . "cytolib")))
     (build-system r-build-system)
     (native-inputs
@@ -12695,24 +13047,24 @@ interact with gated cytometry data.")
 (define-public r-flowcore
   (package
     (name "r-flowcore")
-    (version "2.8.0")
+    (version "2.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "flowCore" version))
        (sha256
         (base32
-         "17nci6rc4i0vs0ibw5q8zy30ap7q4550qpq4ifkbblqbyzxlzkhr"))))
+         "0j0ryyz3vcih964is5gdm2jp39ssdli9q6r03q6rj9nwzplq5asj"))))
     (properties `((upstream-name . "flowCore")))
     (build-system r-build-system)
     (propagated-inputs
      (list r-bh
            r-biobase
            r-biocgenerics
+           r-cpp11
            r-cytolib
            r-matrixstats
            r-rcpp
-           r-rcpparmadillo
            r-rprotobuflib
            r-s4vectors))
     (native-inputs
@@ -12727,14 +13079,14 @@ with flow cytometry data.")
 (define-public r-flowmeans
   (package
     (name "r-flowmeans")
-    (version "1.56.0")
+    (version "1.58.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "flowMeans" version))
        (sha256
         (base32
-         "1n4li43ydwwf5gvgmdml4ba28cxymybg5wnz6jvp35n959fwxv6y"))))
+         "1hmr2i5svg1wvdgqhnp25k1c21p2pdd0ia9py5kp9sm5qvc9vngw"))))
     (properties `((upstream-name . "flowMeans")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12750,14 +13102,14 @@ change point detection.")
 (define-public r-ncdfflow
   (package
     (name "r-ncdfflow")
-    (version "2.42.1")
+    (version "2.44.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ncdfFlow" version))
        (sha256
         (base32
-         "0759xvkp22dnbhq5wpgvpk8p61w0d50r5jrbh9n7sj8sga4lvvv7"))))
+         "0ak1rrd0r899nz4zdg9v3pkvlp94sbcc3q6xl249krgbx0a3sizm"))))
     (properties `((upstream-name . "ncdfFlow")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12781,14 +13133,14 @@ manipulation of flow cytometry data.")
 (define-public r-ggcyto
   (package
     (name "r-ggcyto")
-    (version "1.24.1")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ggcyto" version))
        (sha256
         (base32
-         "1cw60x78vqzjmgb5xd3sxyz6zwdaffp3byk34z8d4b3wkh530325"))))
+         "0phhm54wcqihj62a0jk46whmf6wwg7wj3306wvnszy7yik4z857w"))))
     (properties `((upstream-name . "ggcyto")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12818,14 +13170,14 @@ statistics to the plot.")
 (define-public r-flowviz
   (package
     (name "r-flowviz")
-    (version "1.60.2")
+    (version "1.62.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "flowViz" version))
        (sha256
         (base32
-         "08rwzc26jns0wwjsqqmf60bpxsckr5x8skdn9iwl8grp81npcc95"))))
+         "0yz2b3l0bv5i7vrr893wrs3jl215i17m2hr92iisdc6mh9i0lpz8"))))
     (properties `((upstream-name . "flowViz")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12849,14 +13201,14 @@ statistics to the plot.")
 (define-public r-flowclust
   (package
     (name "r-flowclust")
-    (version "3.34.0")
+    (version "3.36.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "flowClust" version))
        (sha256
         (base32
-         "055vm9s8aha92znhpjqkipzprw8bkrinwjaik4ygmhym7w6vbblk"))))
+         "1l1lfgm6x06gyzda36m6gvqmb91zbrz8m83b1fnfzpxkhqha20yq"))))
     (properties `((upstream-name . "flowClust")))
     (build-system r-build-system)
     (arguments
@@ -12883,14 +13235,14 @@ model with Box-Cox transformation.")
 (define-public r-rprotobuflib
   (package
     (name "r-rprotobuflib")
-    (version "2.8.0")
+    (version "2.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "RProtoBufLib" version))
        (sha256
         (base32
-         "1mvqwrm1y0vij66gdwgpf5l1h660wsi9jzjfs4ihw3zm4cb0q5pp"))))
+         "07d5skr8cp0hyjbs7whw4h8scrf2w4hyn0wzj3khqdss53zmmr2m"))))
     (properties `((upstream-name . "RProtoBufLib")))
     (build-system r-build-system)
     (arguments
@@ -12912,14 +13264,14 @@ for other R packages to compile and link against.")
 (define-public r-flowworkspace
   (package
     (name "r-flowworkspace")
-    (version "4.8.0")
+    (version "4.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "flowWorkspace" version))
        (sha256
         (base32
-         "0riyi9628cx1j5x6hmdd28yq75xh25j8ckcdz8dnb94dpvnhaqss"))))
+         "07w2pnnzmivfc621c8pvndqrn1k245cwjrb0nnk2i85i3si4j9c3"))))
     (properties `((upstream-name . "flowWorkspace")))
     (build-system r-build-system)
     (propagated-inputs
@@ -12966,14 +13318,14 @@ matches the flowJo analysis.")
 (define-public r-flowstats
   (package
     (name "r-flowstats")
-    (version "4.8.2")
+    (version "4.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "flowStats" version))
        (sha256
         (base32
-         "1x01gg5ifxh3wp0cp5a23lr9v6l9q5qg8145q2pgn904jkx5wldc"))))
+         "10xq0rfnshvam2yh34566ywmsby44aa1fg8wqwmllm202rhcgl2p"))))
     (properties `((upstream-name . "flowStats")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13004,14 +13356,14 @@ package.")
 (define-public r-opencyto
   (package
     (name "r-opencyto")
-    (version "2.8.4")
+    (version "2.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "openCyto" version))
        (sha256
         (base32
-         "0fa3hbbrjw458dhmxdjypcjgyxmphp9kdr3r62qqf803i4wsxfk0"))))
+         "1pkpm98fs17zqdvyymd58sl4cib7gdi7drvdkagilrafjcrpq31m"))))
     (properties `((upstream-name . "openCyto")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13048,14 +13400,14 @@ sequential way to mimic the manual gating strategy.")
 (define-public r-cytoml
   (package
     (name "r-cytoml")
-    (version "2.8.1")
+    (version "2.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "CytoML" version))
        (sha256
         (base32
-         "01yzdljpyq92bv318b5qs29f190226zwbqjnckvxmbb0k8m7s5hw"))))
+         "105vdmwwglknwk7x7cb6b2jf6bngbxsly0ymjf8175p2lfv98jsa"))))
     (properties `((upstream-name . "CytoML")))
     (build-system r-build-system)
     (inputs
@@ -13100,14 +13452,14 @@ standard to exchange gated cytometry data with other software platforms.")
 (define-public r-flowsom
   (package
     (name "r-flowsom")
-    (version "2.4.0")
+    (version "2.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "FlowSOM" version))
        (sha256
         (base32
-         "0balsds5mm981cqamdjv3ndq1y9arharisd6f2lrpkzgvwawa645"))))
+         "1s7xilhhc55igq0zmvpfzhnh5df8bzmm3daknz75xhzhhg5b7z1c"))))
     (properties `((upstream-name . "FlowSOM")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13143,14 +13495,14 @@ self-organizing map clustering and minimal spanning trees.")
 (define-public r-mixomics
   (package
     (name "r-mixomics")
-    (version "6.20.0")
+    (version "6.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "mixOmics" version))
        (sha256
         (base32
-         "0fwc2w7frj0bjijzfckkxf7ipx1z13gw7907q4zr5qfl9mh127w7"))))
+         "0w6shihvnvkjycba1hy8drd8wcxxcl2rimkrb4vdl8aygdifrarx"))))
     (properties `((upstream-name . "mixOmics")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13189,14 +13541,14 @@ delete entire rows with missing data.")
 (define-public r-depecher
   (package                              ;Source/Weave error
     (name "r-depecher")
-    (version "1.12.0")
+    (version "1.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DepecheR" version))
        (sha256
         (base32
-         "0rixczdds5gpac50wap6s68kmpdj4208l38gcihkrysz5frbvqjp"))))
+         "1j4gxgw1s3a0nm888k02qi1smxqsplc42827ks666md025h9bxcj"))))
     (properties `((upstream-name . "DepecheR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13235,14 +13587,14 @@ data, to only emphasize the data that actually matters.")
 (define-public r-rcistarget
   (package
     (name "r-rcistarget")
-    (version "1.16.0")
+    (version "1.17.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "RcisTarget" version))
        (sha256
         (base32
-         "17fnjkg6rjqj33v7slg81skqag10y6dc14g5iv69gqshjal4w4im"))))
+         "1anwin5476q2n0zgywrmp3nj6sgy07i6pw1lczydvn4h1a8n1rvk"))))
     (properties `((upstream-name . "RcisTarget")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13277,14 +13629,14 @@ genes in the gene-set that are ranked above the leading edge).")
 (define-public r-chicago
   (package
     (name "r-chicago")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Chicago" version))
        (sha256
         (base32
-         "13vzxmvxpc3r9gii37zvhhr5nbnaggrva97g6m2n02qn9daf6vmm"))))
+         "1b24iiy6d5kzpixgpdkg4s1cb50jdrmgn9sjgvwr1qinckwz6zdn"))))
     (properties `((upstream-name . "Chicago")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13323,14 +13675,14 @@ expression space.")
 (define-public r-cicero
   (package
     (name "r-cicero")
-    (version "1.14.0")
+    (version "1.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "cicero" version))
        (sha256
         (base32
-         "1ip12ijazlmcfbym078slxykpkz7d1zwvs8l8aqdnqpxjfk1ipx5"))))
+         "0grzp9k06dz04bw07nf9qka19mara1kplyd24y8mg8208wk949f6"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-assertthat
@@ -13390,14 +13742,14 @@ accessibility data.")
 (define-public r-circrnaprofiler
   (package
     (name "r-circrnaprofiler")
-    (version "1.10.0")
+    (version "1.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "circRNAprofiler" version))
        (sha256
         (base32
-         "1gwm416shhv2p3gh1n6kv1rvx0n0imy25b7z62z4s8b3gs3nfp5j"))))
+         "07l8vaqbw36hvs8pyn1gk6dglnmkcmbafvd4rdrhg2wqwnlpsf40"))))
     (properties
      `((upstream-name . "circRNAprofiler")))
     (build-system r-build-system)
@@ -13525,14 +13877,14 @@ cisTopics and explore the nature and regulatory proteins driving them.")
 (define-public r-genie3
   (package
     (name "r-genie3")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GENIE3" version))
        (sha256
         (base32
-         "0h3vnpnznb9rda8gfwp4cnd2mqsvs1vzmfx90dchn5pqaphz1k2l"))))
+         "096crx7n75x60s9sx3l7nld3yvrsqs0clvjsdarxc6bbn2qxk81i"))))
     (properties `((upstream-name . "GENIE3")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13549,14 +13901,14 @@ regulatory networks from expression data.")
 (define-public r-roc
   (package
     (name "r-roc")
-    (version "1.72.0")
+    (version "1.74.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ROC" version))
        (sha256
         (base32
-         "0yfq0d0j2bzqdnjs6l2h6p48kmv9wfphlqym3brgndlnadipq1v2"))))
+         "00pw6xmxjzprbx8wskq6gbyqkfak764vic5yxrzs6wpram352vmv"))))
     (properties `((upstream-name . "ROC")))
     (build-system r-build-system)
     (native-inputs
@@ -13571,14 +13923,14 @@ Characteristic} (ROC) curves, with a focus on micro arrays.")
 (define-public r-watermelon
   (package
     (name "r-watermelon")
-    (version "2.2.0")
+    (version "2.4.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "wateRmelon" version))
        (sha256
         (base32
-         "0adqyfabrvfcaj3mwp0rbqlcgpj92yb205cyhibbrs5gdr5ri4pv"))))
+         "0m8mra0jb6sgm13dagqn1pj81dha4dyj65xc6r2sh0yc3pyjb20h"))))
     (properties `((upstream-name . "wateRmelon")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13609,14 +13961,14 @@ metrics, with methods for objects produced by the @code{methylumi} and
 (define-public r-gdsfmt
   (package
     (name "r-gdsfmt")
-    (version "1.32.0")
+    (version "1.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "gdsfmt" version))
        (sha256
         (base32
-         "1cdwyivgfc6yw5hj9b3j57wx55gckwhx6fwx2lvqynrjzjyzf3q0"))
+         "1ck3qq4vhjp6vvicpldr7d2rkpspp5albjkbqjbshnbq11fhrk06"))
        (modules '((guix build utils)))
        ;; Remove bundled sources of zlib, lz4, and xz.  Don't attempt to build
        ;; them and link with system libraries instead.
@@ -13665,14 +14017,14 @@ with multiple R processes supported by the package @code{parallel}.")
 (define-public r-bigmelon
   (package
     (name "r-bigmelon")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "bigmelon" version))
        (sha256
         (base32
-         "1msch4qbifkdqv0bbw03xj6d9w28z91mf4ki41rqg6048cq17h2k"))))
+         "094d43yv8af8sijp43ndcaincnsf3ng32vgwh6bfazlq5d601r6y"))))
     (properties `((upstream-name . "bigmelon")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13696,14 +14048,14 @@ with multiple R processes supported by the package @code{parallel}.")
 (define-public r-seqbias
   (package
     (name "r-seqbias")
-    (version "1.44.0")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "seqbias" version))
        (sha256
         (base32
-         "085nq6pf0bdn17wsbr5jnyy512v7rf67xff9rp5wz47mcifbv6rg"))))
+         "0mc6lv7vkch138n46gk1q1hfhv37mfxjij39q36wa0jy7s8cagfa"))))
     (properties `((upstream-name . "seqbias")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13720,14 +14072,14 @@ genome sequence.")
 (define-public r-reqon
   (package
     (name "r-reqon")
-    (version "1.42.0")
+    (version "1.44.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ReQON" version))
        (sha256
         (base32
-         "1f5pplm8fy3wvl0b6n18gph4dq9i9x5qiyjrj0bk0kwlkbpba74r"))))
+         "1r4dzwnqv6a4zy5q9l3axqq23sbk9pjfb2y3fmwxjvdwq6c1qnp0"))))
     (properties `((upstream-name . "ReQON")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13743,14 +14095,14 @@ format.")
 (define-public r-wavcluster
   (package
     (name "r-wavcluster")
-    (version "2.30.0")
+    (version "2.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "wavClusteR" version))
        (sha256
         (base32
-         "04di095i9i19j9ppx8gdsk7n18vd02d4rjdi9d4a3p0xv05ihnb6"))))
+         "1z7y3wnrqr2xqrvs2xwmv419aqlizq0az17dpxmj1hg9knyls1bx"))))
     (properties `((upstream-name . "wavClusteR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -13831,14 +14183,14 @@ provides methods for retrieving enriched pathways.")
 (define-public r-variantfiltering
   (package
     (name "r-variantfiltering")
-    (version "1.32.0")
+    (version "1.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "VariantFiltering" version))
        (sha256
         (base32
-         "1bjqn8qik221x0bqvgd99p87v45iihwp6cxckh4ks964pd0c1xk8"))))
+         "110db9gcla796mbll3pin0hv2qp8r6khx0zzqfgzkp4mcyjxi62y"))))
     (properties
      `((upstream-name . "VariantFiltering")))
     (build-system r-build-system)
@@ -13937,14 +14289,14 @@ arrays based on fast wavelet-based functional models.")
 (define-public r-variancepartition
   (package
     (name "r-variancepartition")
-    (version "1.26.0")
+    (version "1.28.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "variancePartition" version))
        (sha256
         (base32
-         "0wk1xql8b0gxyrqz9hs54xvmp7qdw9b8jnv88p4vgv061iwyk7wv"))))
+         "1mn91r0yrhz08m3vs2h3i35rcbxyc7sdfknmk6vcw1z75znjsnpl"))))
     (properties
      `((upstream-name . "variancePartition")))
     (build-system r-build-system)
@@ -13985,14 +14337,14 @@ measures.")
 (define-public r-htqpcr
   (package
     (name "r-htqpcr")
-    (version "1.50.0")
+    (version "1.52.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "HTqPCR" version))
        (sha256
         (base32
-         "0am98rzwpi3kybq1l27c5qn3n1pg5aqwmh6jq9q0lzbjjin3haqc"))))
+         "1kclvh8f2sf534cjw07ry9nx74n6p7r0vmc3mk2nr37yvpf26b3q"))))
     (properties `((upstream-name . "HTqPCR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14015,14 +14367,14 @@ features (e.g.  genes, microRNAs).")
 (define-public r-unifiedwmwqpcr
   (package
     (name "r-unifiedwmwqpcr")
-    (version "1.32.0")
+    (version "1.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "unifiedWMWqPCR" version))
        (sha256
         (base32
-         "1skfs94a6bv05c844zf5vfqw1fbgxyppgdnckdbhxg2a2470a4wh"))))
+         "0zkqr1s8gagwsh33kzp0n2n7ff5jhfn6a60gvab5spk7vr76j442"))))
     (properties
      `((upstream-name . "unifiedWMWqPCR")))
     (build-system r-build-system)
@@ -14039,14 +14391,14 @@ data.")
 (define-public r-universalmotif
   (package
     (name "r-universalmotif")
-    (version "1.14.1")
+    (version "1.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "universalmotif" version))
        (sha256
         (base32
-         "1sm54z8aq3534qjsa19wychhwcvwnjlkydmiqqvidiiwcxwqpjsr"))))
+         "1vfg703wxbgxw2cwqqz3kfyqj4za5n3skxxzi8c31azamg4hxs18"))))
     (properties
      `((upstream-name . "universalmotif")))
     (build-system r-build-system)
@@ -14087,13 +14439,13 @@ motifs, and others.")
 (define-public r-ace
   (package
     (name "r-ace")
-    (version "1.14.0")
+    (version "1.16.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ACE" version))
               (sha256
                (base32
-                "1xnw288vz810vjkidar5h218wyc0q2hx0k4zi3r88vaz5rfhc05m"))))
+                "12gmdkzm9wnrq793xqvw3mzwmmsm1vkh36llapr7m7q4dmcfgxr0"))))
     (properties `((upstream-name . "ACE")))
     (build-system r-build-system)
     (propagated-inputs (list r-biobase r-genomicranges r-ggplot2 r-qdnaseq))
@@ -14116,13 +14468,13 @@ of @dfn{tumor cells} (cells with divergent segments).")
 (define-public r-acgh
   (package
     (name "r-acgh")
-    (version "1.74.0")
+    (version "1.76.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "aCGH" version))
               (sha256
                (base32
-                "00ni0kwy68v33ggfi8g5vffirhmbhaxg4l54hcqhx75m535z1x7d"))))
+                "05q303bf8acvhbdzqxqk2gf12vg0fdqknlxryn2cs8nijx40zp46"))))
     (properties `((upstream-name . "aCGH")))
     (build-system r-build-system)
     (propagated-inputs (list r-biobase r-cluster r-multtest r-survival))
@@ -14140,13 +14492,13 @@ printing and plotting @code{aCGH} objects.")
 (define-public r-acme
   (package
     (name "r-acme")
-    (version "2.52.0")
+    (version "2.54.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "ACME" version))
               (sha256
                (base32
-                "0ilcsgpc4m47gifxc0yzx2xi3g4day515mncnnjvfdj3iq8xwk25"))))
+                "0prcaxqmzm4hhpv228xh0glhm166gs17sa9h4lqrm03pwrjrdqdw"))))
     (properties `((upstream-name . "ACME")))
     (build-system r-build-system)
     (propagated-inputs (list r-biobase r-biocgenerics))
@@ -14167,13 +14519,13 @@ on whole-genome tiling array experiments quite easily with enough memory.")
 (define-public r-acde
   (package
     (name "r-acde")
-    (version "1.26.0")
+    (version "1.28.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "acde" version))
               (sha256
                (base32
-                "0lgq546y4qklfzbc6fjr3d656hn76p6dn4694qfiafql2nlsjbj2"))))
+                "1d47hbna68qm517afk1wb0w9gb8j52p7nqh5axcc6h76zppsc1sp"))))
     (properties `((upstream-name . "acde")))
     (build-system r-build-system)
     (propagated-inputs (list r-boot))
@@ -14260,14 +14612,14 @@ cellular organization in health and disease.")
 (define-public r-bgmix
   (package
     (name "r-bgmix")
-    (version "1.56.0")
+    (version "1.58.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BGmix" version))
        (sha256
         (base32
-         "03f6nknp3n49yvg2d9qsmds676rva70pr4wjz0md228jczgjk0vj"))))
+         "0r4cxrjvf3qr5514lsw1s53h4by3djb9ipkz7bi979w343dn9xfx"))))
     (properties `((upstream-name . "BGmix")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14282,14 +14634,14 @@ gene expression.")
 (define-public r-bgx
   (package
     (name "r-bgx")
-    (version "1.62.0")
+    (version "1.64.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "bgx" version))
        (sha256
         (base32
-         "0q2y4n6bcc9pvz5sgfkw1lrb00rrp7q29i1vh7srdfmfhgpyz6bk"))))
+         "1ylg9bnq8iwax0ap4c19v4mkbq673s8dfv49d94znsryg3fp93dl"))))
     (properties `((upstream-name . "bgx")))
     (build-system r-build-system)
     (arguments
@@ -14318,14 +14670,14 @@ Affymetrix GeneChips.")
 (define-public r-bhc
   (package
     (name "r-bhc")
-    (version "1.48.0")
+    (version "1.50.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BHC" version))
        (sha256
         (base32
-         "1kqajd16981y5yaak2imaq1i7pilgqdr3nbhggsakh787j1d9rc5"))))
+         "0ryd9lg8pywqlxj802y9jad5nxy40ivnzdq2ldldypwyalgk9ahm"))))
     (properties `((upstream-name . "BHC")))
     (build-system r-build-system)
     (home-page "https://bioconductor.org/packages/BHC/")
@@ -14344,14 +14696,14 @@ algorithm which is more efficient for larger data sets.")
 (define-public r-bicare
   (package
     (name "r-bicare")
-    (version "1.54.0")
+    (version "1.56.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BicARE" version))
        (sha256
         (base32
-         "0qjh5bsjcjry6k1vzdaascwy2shjrkc2bw0w57w0qa458cbi89z2"))))
+         "1z7x30705a4ww9vdam2668pk064na5ispigqnaqy8zqvlfvp3c8d"))))
     (properties `((upstream-name . "BicARE")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14366,14 +14718,14 @@ results.")
 (define-public r-bifet
   (package
     (name "r-bifet")
-    (version "1.16.0")
+    (version "1.18.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiFET" version))
        (sha256
         (base32
-         "03ypbbn8i0f4bl4m6wfdcv702jydniak56wqjb1vlrckd9aphwzq"))))
+         "0awzq3i7ga6jsh7xgmrpzz8klx69p8cxj73p6h7ya43bgcr0iff0"))))
     (properties `((upstream-name . "BiFET")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14395,14 +14747,14 @@ the read count and GC content bias.")
 (define-public r-rsbml
   (package
     (name "r-rsbml")
-    (version "2.54.0")
+    (version "2.56.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "rsbml" version))
        (sha256
         (base32
-         "1v11pspkml6xdsacgwxw8r4qdhbnn2h2sqgpm9aidaq9p2085b0v"))))
+         "1syg49qz6vwzyw2zrxwrfb7kzgk0lim1q674f7mfvjah1fnv8bgc"))))
     (properties `((upstream-name . "rsbml")))
     (build-system r-build-system)
     (inputs
@@ -14421,14 +14773,14 @@ validating output, provides an S4 SBML DOM, converts SBML to R graph objects.")
 (define-public r-hypergraph
   (package
     (name "r-hypergraph")
-    (version "1.68.0")
+    (version "1.70.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "hypergraph" version))
        (sha256
         (base32
-         "0xmryqj5yw1ns6wbhjqbb6h14jlj89zrznzvqnvd4n03ci20kzzp"))))
+         "1jvnvzjivjwqxh19c3g37kpyl6i6mxw99ma3ypjjgxzx898nsg45"))))
     (properties `((upstream-name . "hypergraph")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14443,14 +14795,14 @@ manipulating hypergraphs.")
 (define-public r-hyperdraw
   (package
     (name "r-hyperdraw")
-    (version "1.48.0")
+    (version "1.50.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "hyperdraw" version))
        (sha256
         (base32
-         "0ndw4y6b15jy4w86vfkahmdc81d3ycjsvqy1mxi55dwvd8xq0ap6"))))
+         "1fl4ia2jskvmbwk0y1wd0x4dgqph0av7bx2zffrvd1a5ppcjmsra"))))
     (properties `((upstream-name . "hyperdraw")))
     (build-system r-build-system)
     (inputs (list graphviz))
@@ -14465,14 +14817,14 @@ manipulating hypergraphs.")
 (define-public r-biggr
   (package
     (name "r-biggr")
-    (version "1.32.0")
+    (version "1.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiGGR" version))
        (sha256
         (base32
-         "0n57bgl6xz5b1gpw4isimq2pqxmlabn7jzhbjg2fbxcklabdvrcw"))))
+         "07b80qpkbas3x2yhndcm6vdkba0cpricyvnjf18dxklj5j612wfy"))))
     (properties `((upstream-name . "BiGGR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14529,14 +14881,14 @@ a file-backed matrix with factor properties.")
 (define-public r-bigpint
   (package
     (name "r-bigpint")
-    (version "1.12.0")
+    (version "1.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "bigPint" version))
        (sha256
         (base32
-         "1hp69j2qcidrxqs3dxjjngb09nbzp5x2yy4jz1rjmv6ghif9ccfj"))))
+         "1smf3w5a60jc0bpip5131ad9ykmnrcd33qi3pc3m50g6kn023wz2"))))
     (properties `((upstream-name . "bigPint")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14572,14 +14924,14 @@ visualizing RNA-sequencing datasets and differentially expressed genes.")
 (define-public r-chemminer
   (package
     (name "r-chemminer")
-    (version "3.48.0")
+    (version "3.50.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ChemmineR" version))
        (sha256
         (base32
-         "1nri4zkc9lp1mqgsi0h58486vixwiv2989b6pmx2aj5c3575i0ma"))))
+         "0rk4ydanqxjh5yj0m9qlj06a12j7rkx9gxv6x7zpiyvnscahw63i"))))
     (properties `((upstream-name . "ChemmineR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14615,13 +14967,13 @@ structures.")
 (define-public r-fmcsr
   (package
     (name "r-fmcsr")
-    (version "1.38.0")
+    (version "1.40.0")
     (source
       (origin
         (method url-fetch)
         (uri (bioconductor-uri "fmcsR" version))
         (sha256
-          (base32 "1mblmk21dxc9v2fikhvfg2njwgl190gkysppl6msxizwcmxsmh30"))))
+          (base32 "00xi01wz61ip8pnbrpnpp8hncb8gyiw69qkbg0cl425rv6qjb3mr"))))
     (properties `((upstream-name . "fmcsR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14644,14 +14996,14 @@ searching and clustering.")
 (define-public r-bioassayr
   (package
     (name "r-bioassayr")
-    (version "1.34.0")
+    (version "1.36.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "bioassayR" version))
        (sha256
         (base32
-         "0zbrci0vgk4qca28i0qb2izhyrz3r95l1w54h9h3zj9f3vd61wrz"))))
+         "0r56r4qxibgblriyfbd46i8jhc2bfr9ndr8i30920v9kc3n83cav"))))
     (properties `((upstream-name . "bioassayR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14679,14 +15031,14 @@ available bioactivity data.")
 (define-public r-biobroom
   (package
     (name "r-biobroom")
-    (version "1.28.0")
+    (version "1.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biobroom" version))
        (sha256
         (base32
-         "04x1z9nchm4mbhqr31011zdprc4md156j4zf003s7xx0n278xsgh"))))
+         "02gdc26bs0yx7hb53b8ncipsaw6ynfvjcx64qxkxxq1c4awjkhzy"))))
     (properties `((upstream-name . "biobroom")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14708,18 +15060,18 @@ visualize bioinformatics analyses.")
 (define-public r-graphite
   (package
     (name "r-graphite")
-    (version "1.42.0")
+    (version "1.44.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "graphite" version))
        (sha256
         (base32
-         "0nl5mkgrvf7vsqjy48ij9b1dmxfvp9lf8cpay55h93c4qz4x606g"))))
+         "0gkjab12ncag1vslc5bwlr0m5ac3ifq9ka5nfq7ckrpns98s7k0w"))))
     (properties `((upstream-name . "graphite")))
     (build-system r-build-system)
     (propagated-inputs
-     (list r-annotationdbi r-graph r-httr r-rappdirs r-rlang))
+     (list r-annotationdbi r-graph r-httr r-purrr r-rappdirs r-rlang))
     (home-page "https://bioconductor.org/packages/graphite/")
     (synopsis "Networks from pathway databases")
     (description
@@ -14731,14 +15083,14 @@ symbols).")
 (define-public r-reactomepa
   (package
     (name "r-reactomepa")
-    (version "1.40.0")
+    (version "1.42.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ReactomePA" version))
        (sha256
         (base32
-         "1fd72m2afxbbvbgwy8knp6fiq1h561plmsh4r8a08w21ngmkz2s5"))))
+         "06994hk9nrzlgz8sby61656rdbf1r954v71djl1i7141dgw5rif2"))))
     (properties `((upstream-name . "ReactomePA")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14748,6 +15100,7 @@ symbols).")
            r-ggplot2
            r-ggraph
            r-graphite
+           r-gson
            r-igraph
            r-reactome-db))
     (native-inputs
@@ -14763,14 +15116,14 @@ enrichment analysis and several functions for visualization.")
 (define-public r-ebarrays
   (package
     (name "r-ebarrays")
-    (version "2.60.0")
+    (version "2.62.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "EBarrays" version))
        (sha256
         (base32
-         "027zarnpxpdnyl877swp5ypxj7zvq0cjp2q2xs6g6yn5dpqjvxxk"))))
+         "0kg22appd9sd6knm129hchkamzilwr3h8wi4ibrvllbfmx31v9q8"))))
     (properties `((upstream-name . "EBarrays")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14782,6 +15135,28 @@ enrichment analysis and several functions for visualization.")
 microarray data.")
     (license license:gpl2+)))
 
+(define-public r-biocbaseutils
+  (package
+    (name "r-biocbaseutils")
+    (version "1.0.0")
+    (source (origin
+              (method url-fetch)
+              (uri (bioconductor-uri "BiocBaseUtils" version))
+              (sha256
+               (base32
+                "0p6siidrx8q6qr36fc67hzi091m2zwik3zngj27yllbfz6sn5k69"))))
+    (properties `((upstream-name . "BiocBaseUtils")))
+    (build-system r-build-system)
+    (native-inputs (list r-knitr))
+    (home-page "https://bioconductor.org/packages/BiocBaseUtils")
+    (synopsis "General utility functions for developing Bioconductor packages")
+    (description
+     "The package provides utility functions related to package development.
+These include functions that replace slots, and selectors for show methods.
+It aims to coalesce the various helper functions often re-used throughout the
+Bioconductor ecosystem.")
+    (license license:artistic2.0)))
+
 (define-public r-bioccasestudies
   (package
     (name "r-bioccasestudies")
@@ -14807,13 +15182,13 @@ monograph.")
 (define-public r-bioccheck
   (package
     (name "r-bioccheck")
-    (version "1.32.1")
+    (version "1.34.2")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BiocCheck" version))
               (sha256
                (base32
-                "0bq4xrz1spp0bmbccxydkw6yw03by5dysz85mn152ab6xixm52lw"))))
+                "1zj43kbzvi2ws8c182fp6vn5r6iiqsr6p2iyy3k8n3ifm2acqw2h"))))
     (properties
      `((upstream-name . "BiocCheck")))
     (build-system r-build-system)
@@ -14836,14 +15211,14 @@ checks on R packages that are to be submitted to the Bioconductor repository.")
 (define-public r-biocgraph
   (package
     (name "r-biocgraph")
-    (version "1.58.0")
+    (version "1.60.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biocGraph" version))
        (sha256
         (base32
-         "1y59a7c4ahhn1g2wz2hkx83izfn8i85mmxxp63jdd0rg7zwhr6nn"))))
+         "0ysdmv2hyl8jnmr42lkyvgfqb0z89f5p649ahx0ygs6fw0z226xa"))))
     (properties `((upstream-name . "biocGraph")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14858,13 +15233,13 @@ different graph related packages produced by Bioconductor.")
 (define-public r-biocstyle
   (package
     (name "r-biocstyle")
-    (version "2.24.0")
+    (version "2.26.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "BiocStyle" version))
               (sha256
                (base32
-                "1nwiib201b9q1x19ihqjqr5jl0vnid8wfgpi8sa3y02bn722g5a5"))))
+                "092hpmyhra755j32vc8w2l6xqwg09jm8apnk5rvxi1cm5034yvsl"))))
     (properties
      `((upstream-name . "BiocStyle")))
     (build-system r-build-system)
@@ -14882,13 +15257,13 @@ functionality.")
 (define-public r-biocviews
   (package
     (name "r-biocviews")
-    (version "1.64.1")
+    (version "1.66.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "biocViews" version))
               (sha256
                (base32
-                "0ixcx9qqpmwmnhml3klk5z075km8g2l4q0iqc1dbniga87qgyl38"))))
+                "1rgn0agw5m4y8838lxzq1r658h1pblaidmm444yfimjffa8znj23"))))
     (properties
      `((upstream-name . "biocViews")))
     (build-system r-build-system)
@@ -14910,14 +15285,14 @@ also known as views, in a controlled vocabulary.")
 (define-public r-experimenthub
   (package
     (name "r-experimenthub")
-    (version "2.4.0")
+    (version "2.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ExperimentHub" version))
        (sha256
         (base32
-         "11hna8vrm1az1zk7pw2dv0wh84sd0hw2bi55w40hqvs36csb7lkl"))))
+         "1j71zmxwiz82gg6kii2bmynzwll1r6fmsq972kmvxvm6crpvi15s"))))
     (properties `((upstream-name . "ExperimentHub")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14944,14 +15319,14 @@ access.")
 (define-public r-grohmm
   (package
     (name "r-grohmm")
-    (version "1.30.1")
+    (version "1.32.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "groHMM" version))
        (sha256
         (base32
-         "0v2mk7xcy483w2nygpmyjp73kj3v5pkk1kf1wr41n33dxqlddqai"))))
+         "1as3k6avyc4l7saw02x0ql68c06msvs1s824vc1xg6lkdsi4lsyc"))))
     (properties `((upstream-name . "groHMM")))
     (build-system r-build-system)
     (propagated-inputs
@@ -14971,20 +15346,22 @@ access.")
 (define-public r-multiassayexperiment
   (package
     (name "r-multiassayexperiment")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MultiAssayExperiment" version))
        (sha256
         (base32
-         "1wnp52l9vifxn1wzqgndzp9b6ih0s1cflxx1fhw32k32d05cw9q1"))))
+         "00lhnqa4yz3lm5kl79bghad93iijihnassy2caf87czc540why09"))))
     (properties
      `((upstream-name . "MultiAssayExperiment")))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biobase
+           r-biocbaseutils
            r-biocgenerics
+           r-delayedarray
            r-genomicranges
            r-iranges
            r-s4vectors
@@ -15006,14 +15383,14 @@ rownames.")
 (define-public r-bioconcotk
   (package
     (name "r-bioconcotk")
-    (version "1.16.0")
+    (version "1.18.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocOncoTK" version))
        (sha256
         (base32
-         "1alplszw84vqa1mvzp996f94s40scmh4qwbrqhg43hrnyvbnq7pi"))))
+         "1x4mzzjvjgcxg5xyxjib8r2n55hpf2vzcci0xkb7d8frakfncn9s"))))
     (properties `((upstream-name . "BiocOncoTK")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15051,14 +15428,14 @@ tools for genome-scale analysis of cancer studies.")
 (define-public r-biocor
   (package
     (name "r-biocor")
-    (version "1.20.0")
+    (version "1.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BioCor" version))
        (sha256
         (base32
-         "004mksswampwisljcdz6fswwbgdjdii3y86gjzib0gf8v4w7w4q3"))))
+         "0a8xyrmarb2ja5zyvx5sndd67hylmwi29gpr5lwrzinww8w8b8w6"))))
     (properties `((upstream-name . "BioCor")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15078,14 +15455,14 @@ gene selection, testing relationships, and so on.")
 (define-public r-biocpkgtools
   (package
     (name "r-biocpkgtools")
-    (version "1.14.1")
+    (version "1.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocPkgTools" version))
        (sha256
         (base32
-         "0akryshjdn227a8ir8r0lb59v060h58rhy5vjmdxax8p81ajzxkd"))))
+         "1av7vnw6z9cw7j4d3vpi8mfs5h4pn4yr2wc8ybg7ad1d686ah845"))))
     (properties `((upstream-name . "BiocPkgTools")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15105,11 +15482,10 @@ gene selection, testing relationships, and so on.")
            r-rbgl
            r-readr
            r-rlang
+           r-rorcid
            r-rvest
            r-stringr
            r-tibble
-           r-tidyr
-           r-tidyselect
            r-xml2))
     (native-inputs
      (list r-knitr))
@@ -15126,14 +15502,14 @@ analytics on packages.")
 (define-public r-biocset
   (package
     (name "r-biocset")
-    (version "1.10.0")
+    (version "1.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocSet" version))
        (sha256
         (base32
-         "1ghba7020inrdxlbrrgds9gjymjxjma2p89b9lgkjin89zalqglh"))))
+         "197cy5gdlvac7jqwb4dm4dbqfms2nvc3paqs75nsg9mpp1h5z8l8"))))
     (properties `((upstream-name . "BiocSet")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15164,14 +15540,14 @@ accessing web references for elements/sets are also available in BiocSet.")
 (define-public r-biocworkflowtools
   (package
     (name "r-biocworkflowtools")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocWorkflowTools" version))
        (sha256
         (base32
-         "1jj4icpkhrv9f6yx3vghkpdil1pfghf3yvc9756wmndvhs100r5l"))))
+         "00cy5lqmfap57bm2s00bis9ddci2lv1lrp0mk5ydgx061p4ym29i"))))
     (properties
      `((upstream-name . "BiocWorkflowTools")))
     (build-system r-build-system)
@@ -15197,14 +15573,14 @@ Rmarkdown and LaTeX documents when authoring a Bioconductor Workflow.")
 (define-public r-biodist
   (package
     (name "r-biodist")
-    (version "1.68.0")
+    (version "1.70.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "bioDist" version))
        (sha256
         (base32
-         "04nrvrcvpj0sn8p2i8n3ggsl2s7r4na576174i7bn1sj21vr0yb0"))))
+         "1fnx3q5arsilrvnhndplap8h4ydi9bvmlpfllj1li124hn5n2w3d"))))
     (properties `((upstream-name . "bioDist")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15219,14 +15595,14 @@ distance measures.")
 (define-public r-pcatools
   (package
     (name "r-pcatools")
-    (version "2.8.0")
+    (version "2.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "PCAtools" version))
        (sha256
         (base32
-         "03s4dh008fys2rrcpzanc0892p63f6jyyvzc9m42jbi1dlkyx26v"))))
+         "1r32ajjmrhlwl0ylwavlfzph6m01mq3y7r87x8mbkmqw9ld1y2fd"))))
     (properties `((upstream-name . "PCAtools")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15265,18 +15641,40 @@ dimensional mass cytometry data.")
 (define-public r-rgreat
   (package
     (name "r-rgreat")
-    (version "1.28.0")
+    (version "2.0.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "rGREAT" version))
        (sha256
         (base32
-         "0px72r8mjimf5mxfwb9qz46kqpgjw5gaqq41hy0212ymjd8whaky"))))
+         "1vmm7s5p8wqz1r8g1hy1l3mra3kkf76qgy5jkf84jxz7pi0clbld"))))
     (properties `((upstream-name . "rGREAT")))
     (build-system r-build-system)
     (propagated-inputs
-     (list r-genomicranges r-getoptlong r-iranges r-rcurl r-rjson))
+     (list r-annotationdbi
+           r-circlize
+           r-digest
+           r-doparallel
+           r-dt
+           r-foreach
+           r-genomeinfodb
+           r-genomicfeatures
+           r-genomicranges
+           r-getoptlong
+           r-globaloptions
+           r-go-db
+           r-iranges
+           r-org-hs-eg-db
+           r-progress
+           r-rcolorbrewer
+           r-rcurl
+           r-rcpp
+           r-rjson
+           r-s4vectors
+           r-shiny
+           r-txdb-hsapiens-ucsc-hg19-knowngene
+           r-txdb-hsapiens-ucsc-hg38-knowngene))
     (native-inputs (list r-knitr))
     (home-page "https://github.com/jokergoo/rGREAT")
     (synopsis "Client for GREAT analysis")
@@ -15289,14 +15687,14 @@ user's input and automatically retrieving results from GREAT web server.")
 (define-public r-m3c
   (package
     (name "r-m3c")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "M3C" version))
        (sha256
         (base32
-         "120gd7gkgc98d1l6hl2ij799b3jksdnga5iyb44ps9mbc79hl012"))))
+         "1djgbnxsdp1w9hhc6346gmvad3x8avy8nc85gpvg9i4x52wcrn4j"))))
     (properties `((upstream-name . "M3C")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15322,14 +15720,14 @@ hypothesis @code{K=1}.")
 (define-public r-icens
   (package
     (name "r-icens")
-    (version "1.68.0")
+    (version "1.70.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Icens" version))
        (sha256
         (base32
-         "0jnbfv7js8bw0ginql90krrpk0p54whj9igw0zk3jc45jqvj2vyc"))))
+         "13ygc467nqh0235sf1ags1ihv7pg2yriva6qi7z46c534vxv6b8n"))))
     (properties `((upstream-name . "Icens")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15445,14 +15843,14 @@ generated.")
 (define-public r-preprocesscore
   (package
     (name "r-preprocesscore")
-    (version "1.58.0")
+    (version "1.60.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "preprocessCore" version))
        (sha256
         (base32
-         "1sqpp00hhv6gypflrjw8qpqyqgdcp29m86gmi1di1574x8casdkf"))))
+         "1l0m591scln024jdpib47fndhx2wfp9jgkj3mdmwd9nkc5y0qjda"))))
     (properties
      `((upstream-name . "preprocessCore")))
     (build-system r-build-system)
@@ -15466,13 +15864,13 @@ routines.")
 (define-public r-s4vectors
   (package
     (name "r-s4vectors")
-    (version "0.34.0")
+    (version "0.36.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "S4Vectors" version))
               (sha256
                (base32
-                "0j3ybhzdhlhw8527nks3mjja28asjya2n0m0rjkh4bw66rkfys4k"))))
+                "05al4diwdbsa9b37i8msxnp79fxk7k24dk2vhh131s3snb89jvfs"))))
     (properties
      `((upstream-name . "S4Vectors")))
     (build-system r-build-system)
@@ -15533,14 +15931,14 @@ data manipulation and visualization.")
 (define-public r-rgraphviz
   (package
     (name "r-rgraphviz")
-    (version "2.40.0")
+    (version "2.42.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rgraphviz" version))
        (sha256
         (base32
-         "1r6ff7w2bmyfl1vzjvpgnhb8f5arwjlpab8fw5ph8fgyiqbcx94l"))))
+         "0blymdax10zzg2lpj4hgvyh9c01b1qaivrc0gx95swji37zkqnwm"))))
     (properties `((upstream-name . "Rgraphviz")))
     (build-system r-build-system)
     (arguments
@@ -15571,13 +15969,13 @@ objects from the @code{graph} package.")
 (define-public r-fishpond
   (package
     (name "r-fishpond")
-    (version "2.2.0")
+    (version "2.4.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "fishpond" version))
               (sha256
                (base32
-                "0svp4yh0srhzbbxy1grchzdd9yzchadjp3d2sy2n9xpwxzpkhrym"))))
+                "112jd53wbiv1w0n8dc4qn6257wbbbg5i20s9wlvaw98jma94afa6"))))
     (properties `((upstream-name . "fishpond")))
     (build-system r-build-system)
     (inputs (list zlib))
@@ -15609,13 +16007,13 @@ working with Salmon and Alevin quantification files.")
 (define-public r-fithic
   (package
     (name "r-fithic")
-    (version "1.22.0")
+    (version "1.24.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "FitHiC" version))
               (sha256
                (base32
-                "0iv14yx3g7shzl8qrjknyxbmiylj51sbd1wzr1ff9lc5shgl55kq"))))
+                "1c7jscl82knbh5ha1i1hlm46nnhz6aw5h0j5xnl4hlgx8mnn05fl"))))
     (properties `((upstream-name . "FitHiC")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15633,13 +16031,13 @@ assays such as Hi-C.")
 (define-public r-hitc
   (package
     (name "r-hitc")
-    (version "1.40.0")
+    (version "1.42.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "HiTC" version))
               (sha256
                (base32
-                "1pkshlrra26cad0hf8a54brlkazni6rsvrplh36azxapx5rpps4s"))))
+                "10m3pq22a8m8bbfkmq5r44ydg2668g6dxmxp7km47jxgf9hlqhcl"))))
     (properties `((upstream-name . "HiTC")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15662,14 +16060,14 @@ provided.")
 (define-public r-hdf5array
   (package
     (name "r-hdf5array")
-    (version "1.24.2")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "HDF5Array" version))
        (sha256
         (base32
-         "1dzx5463ig3ag72a47slc4jbq5id11w77cj0zgzr85h0dbxklrr9"))))
+         "1y25mlsqf2inij6w2825xxl30bdba971az6rjf7j9bnya3gpvi6h"))))
     (properties `((upstream-name . "HDF5Array")))
     (build-system r-build-system)
     (inputs
@@ -15693,14 +16091,14 @@ block processing.")
 (define-public r-rhdf5lib
   (package
     (name "r-rhdf5lib")
-    (version "1.18.2")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rhdf5lib" version))
        (sha256
         (base32
-         "1jpb8h7c724yz51zjfqs90bsqxgmy1rry2ra9qamsgqpr2j9764g"))
+         "0zxgpc2krfwqzm8c05cdlfs3dyyf5ll43ff9mw8xzj89wcmlcfx7"))
        (modules '((guix build utils)))
        (snippet
         '(begin
@@ -15773,14 +16171,14 @@ packages.")
 (define-public r-beachmat
   (package
     (name "r-beachmat")
-    (version "2.12.0")
+    (version "2.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "beachmat" version))
        (sha256
         (base32
-         "0fc6vvjjq1mfjfj2zqkap3rwvinnfqjs0cpk1447sspvd1rjya8c"))))
+         "0sa1wh997jfiz2y0dr7v12b7pvlf7icgv6arlyqy57winbnqa96m"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biocgenerics r-delayedarray r-matrix r-rcpp))
@@ -15799,13 +16197,13 @@ matrices.")
 (define-public r-cner
   (package
     (name "r-cner")
-    (version "1.32.0")
+    (version "1.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "CNEr" version))
        (sha256
-        (base32 "05zvr5fv8nprxqh2wvvrlf737dq242i20p1rpyqjaxihl6xl62kq"))))
+        (base32 "15y27ca14fdhn2prqgkyikff7p7490xn0bp2c7cnwhw173mm1syw"))))
     (properties `((upstream-name . "CNEr")))
     (build-system r-build-system)
     (inputs (list zlib))
@@ -15847,14 +16245,14 @@ advanced visualization of sets of conserved noncoding elements.")
 (define-public r-tfbstools
   (package
     (name "r-tfbstools")
-    (version "1.34.0")
+    (version "1.36.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "TFBSTools" version))
        (sha256
         (base32
-         "0l6j1r2cx7jfd39qzbyynk4jvzd81ys6yypzxjc97js4kkyrx29w"))))
+         "05kgkwmh5mcrm0xd81rzicysgknb8wrf71y2llikvma1b9c1g789"))))
     (properties `((upstream-name . "TFBSTools")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15893,13 +16291,13 @@ provides a wrapper of de novo motif discovery software.")
 (define-public r-maftools
   (package
     (name "r-maftools")
-    (version "2.12.0")
+    (version "2.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "maftools" version))
        (sha256
-        (base32 "1gqfi95v4fs64n4walij0g2kds3fbbwp6lih5yakmgf6kj8fpkk6"))))
+        (base32 "1f1r0frikaj6aw137dk523gagkxdygg7gzc3pd303ds5cqynwiqx"))))
     (properties `((upstream-name . "maftools")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15922,14 +16320,14 @@ customizable visualzations with minimal effort.")
 (define-public r-motifmatchr
   (package
     (name "r-motifmatchr")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "motifmatchr" version))
        (sha256
         (base32
-         "1ssn00mxwk23zr5na0vcmxvm69i68f0ga0wqlv1nk2isg0wpv878"))))
+         "01k2ngf4nj2cazb3a2c96by86xwdkdngzwhb73n2wadibamnqnfv"))))
     (properties `((upstream-name . "motifmatchr")))
     (build-system r-build-system)
     (propagated-inputs
@@ -15956,13 +16354,13 @@ This package wraps C++ code from the MOODS motif calling library.")
 (define-public r-chromvar
   (package
     (name "r-chromvar")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "chromVAR" version))
        (sha256
-        (base32 "0vhsvkm4kvln0002f13ayk57f9fmiz1kw9vwpsm1vds1vahd656m"))))
+        (base32 "1rwgbicbmszdkr05ksxfsisyhk0a4pvc3jrxbzjyc13jj5h6m5kp"))))
     (properties `((upstream-name . "chromVAR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16003,14 +16401,14 @@ sequence (@code{DNAse-seq}) experiments.")
 (define-public r-singlecellexperiment
   (package
     (name "r-singlecellexperiment")
-    (version "1.18.0")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "SingleCellExperiment" version))
        (sha256
         (base32
-         "0s1aqbvlfnzijzfywjfpinqmxqj269dq2d3zlgf4xw9c1nwwnv7p"))))
+         "1y9c9wf3009w4qh03zpsmc0ff0nkzal673a4nql5c11cn55sza2g"))))
     (properties
      `((upstream-name . "SingleCellExperiment")))
     (build-system r-build-system)
@@ -16031,13 +16429,13 @@ libraries.")
 (define-public r-singler
   (package
     (name "r-singler")
-    (version "1.10.0")
+    (version "2.0.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "SingleR" version))
        (sha256
-        (base32 "0qbyc6ygw2xv3li9187i3axsw6ihwpa7pkvxvy9cagv7xck45c5y"))))
+        (base32 "05rw6l0d4n9m1dd7dp55zfripx036x1riwy83sx3aj5mw4r1awb6"))))
     (properties `((upstream-name . "SingleR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16063,14 +16461,14 @@ cell types to infer the cell of origin of each single cell independently.")
 (define-public r-scuttle
   (package
     (name "r-scuttle")
-    (version "1.6.3")
+    (version "1.8.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "scuttle" version))
        (sha256
         (base32
-         "1w1jy5fqkp2d03lp84d49fsksnl0pcg0wgqyd49d5k1mipdw4671"))))
+         "10wk46zgi57m9q9ab6wlmljcss3fph2r9yp1bp01s9yv7sd749b2"))))
     (properties `((upstream-name . "scuttle")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16098,13 +16496,13 @@ of other packages.")
 (define-public r-scater
   (package
     (name "r-scater")
-    (version "1.24.0")
+    (version "1.26.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "scater" version))
               (sha256
                (base32
-                "0dqirggw7my5nq4ln9q0ya18ciqplkz9gx318ffias9ag3yii5rw"))))
+                "1mjnf2y41lvni77g9hyw8qlvlsi5nxv5ha0fnch1kmw9814nycq3"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-beachmat
@@ -16117,8 +16515,10 @@ of other packages.")
            r-ggbeeswarm
            r-ggplot2
            r-ggrepel
+           r-ggrastr
            r-gridextra
            r-matrix
+           r-pheatmap
            r-rcolorbrewer
            r-rcppml
            r-rlang
@@ -16127,6 +16527,7 @@ of other packages.")
            r-scuttle
            r-singlecellexperiment
            r-summarizedexperiment
+           r-uwot
            r-viridis))
     (native-inputs
      (list r-knitr))
@@ -16140,14 +16541,14 @@ quality control.")
 (define-public r-scran
   (package
     (name "r-scran")
-    (version "1.24.1")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "scran" version))
        (sha256
         (base32
-         "1a6vlq8i5gh7zxm6igmy75187pkx42z28qjag50m49xy5valw3ni"))))
+         "11iwpw44600pfx01vqil97k728m1wf4dljr27k2ak4s7z75kxfih"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-beachmat
@@ -16183,14 +16584,14 @@ variable and significantly correlated genes.")
 (define-public r-sparsematrixstats
   (package
     (name "r-sparsematrixstats")
-    (version "1.8.0")
+    (version "1.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "sparseMatrixStats" version))
        (sha256
         (base32
-         "0p12kay7p5zbfm2589wdx0n9jhgpf5fb2fsmkhn3p4ck4xcy13x2"))))
+         "1rq23ra4nnz9dx0gsg9bh8zcbz6s0pyvjwq30xl6g4hbqz927xb0"))))
     (properties
      `((upstream-name . "sparseMatrixStats")))
     (build-system r-build-system)
@@ -16208,14 +16609,14 @@ data in the column sparse format.")
 (define-public r-delayedmatrixstats
   (package
     (name "r-delayedmatrixstats")
-    (version "1.18.1")
+    (version "1.20.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "DelayedMatrixStats" version))
        (sha256
         (base32
-         "1kq643fmfzq1qjvpj3kc092ahc3qamqgx53layqsyvz5mil55jjv"))))
+         "0qcn7rlq0bsj11sc31wzks2xv900fpmbsblxp9cng5lj5cn2djk3"))))
     (properties
      `((upstream-name . "DelayedMatrixStats")))
     (build-system r-build-system)
@@ -16244,14 +16645,14 @@ memory usage and processing time is minimized.")
 (define-public r-mscoreutils
   (package
     (name "r-mscoreutils")
-    (version "1.8.0")
+    (version "1.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MsCoreUtils" version))
        (sha256
         (base32
-         "077x1zcy27x8akmagjn75j97082cgnahrbfw0qx08q455m5x3xzh"))))
+         "1shrvb2vmvk1m6xk59jqpvrxi8vzcr978aalbx1gjcmaqf6abzcq"))))
     (properties `((upstream-name . "MsCoreUtils")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16273,13 +16674,13 @@ within the R for Mass Spectrometry packages.")
 (define-public r-msfeatures
   (package
     (name "r-msfeatures")
-    (version "1.4.0")
+    (version "1.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MsFeatures" version))
        (sha256
-        (base32 "111iqcq4q315pb4j8z427shin9b00p179m2s9h6dd7imvbd68yq3"))))
+        (base32 "1q1224w31wdaagfv8ysc1w0d0n34y547c0jzkff1vxri9pb0w1j1"))))
     (properties `((upstream-name . "MsFeatures")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16303,14 +16704,14 @@ the respective packages (such as e.g. @code{xcms}).")
 (define-public r-biocio
   (package
     (name "r-biocio")
-    (version "1.6.0")
+    (version "1.8.0")
     (source
       (origin
         (method url-fetch)
         (uri (bioconductor-uri "BiocIO" version))
         (sha256
           (base32
-            "16j826w4zrmbgpmq6nyglcrjailsfv48ih1rz1qn383g7v503ydp"))))
+            "15d4xsn3k32q7lzcyxvs70f0jbh9fgwl3vi7xd6sqpggar12hh9f"))))
     (properties `((upstream-name . "BiocIO")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16336,14 +16737,14 @@ as well as local access.  Developers can register a file extension, e.g.,
 (define-public r-msmseda
   (package
     (name "r-msmseda")
-    (version "1.34.0")
+    (version "1.36.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "msmsEDA" version))
        (sha256
         (base32
-         "0jnaq9ar4mnf3pfhka9hvk61p51ny9jws49xi8z29dq288b42b42"))))
+         "17xklsg483zd205q5hyxy6b3cgrb53pplb1wc7pmv5638y7nsq2v"))))
     (properties `((upstream-name . "msmsEDA")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16359,14 +16760,14 @@ experiments, and visualize de influence of the involved factors.")
 (define-public r-msmstests
   (package
     (name "r-msmstests")
-    (version "1.34.0")
+    (version "1.36.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "msmsTests" version))
        (sha256
         (base32
-         "1wzdz0p9wmr243xkmymx9fwskafkyxgmlip4sd1fy2s06px7r0xi"))))
+         "10frsvqhi3i0v2w4q4q9xz1ykyf6s3nrjlmn94x3kd06p3s839k3"))))
     (properties `((upstream-name . "msmsTests")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16388,14 +16789,14 @@ relevant, and the minimum expression of the most abundant condition.")
 (define-public r-catalyst
   (package
     (name "r-catalyst")
-    (version "1.20.1")
+    (version "1.22.0")
     (source
       (origin
         (method url-fetch)
         (uri (bioconductor-uri "CATALYST" version))
         (sha256
           (base32
-            "05vfqwa9qsm16px77s9bzygs6zymcxshymmpvz86a9l1cy1yxbza"))))
+            "0n3x5w074x5hhgdf2qa0pkma4vrjwrcgjna7hx0az6ixkgpbkrpv"))))
     (properties `((upstream-name . "CATALYST")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16451,14 +16852,14 @@ preprocessing of cytometry data, including:
 (define-public r-erma
   (package
     (name "r-erma")
-    (version "1.12.0")
+    (version "1.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "erma" version))
        (sha256
         (base32
-         "1ilq01cr2ipxpmp422fikiz6nj4nasjhj0ikcagjn2zmmarpgi1b"))))
+         "06zxqzbzb0jrk357900gv1r2n81i49rbmrxla02f879kq2ik9cyd"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi
@@ -16491,14 +16892,14 @@ by Ernst and Kellis.")
 (define-public r-ggbio
   (package
     (name "r-ggbio")
-    (version "1.44.1")
+    (version "1.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ggbio" version))
        (sha256
         (base32
-         "0iyhjalwq1jmldpn20iv8l2kmz6sm20ddry2yz2zn7yq0wszp3vg"))))
+         "1gm3y1nx0ah8wcrg2dh1xd688izm2sijz7bhgsasxckmmkmkp60g"))))
     (build-system r-build-system)
     (arguments
      `(#:phases
@@ -16659,14 +17060,14 @@ family of feature/genome hypotheses.")
 (define-public r-gviz
   (package
     (name "r-gviz")
-    (version "1.40.1")
+    (version "1.42.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Gviz" version))
        (sha256
         (base32
-         "0as3sxhv21bqqrpvafcqim7798hhkzj3q40hy1rqyhv2lhj4rbvi"))))
+         "09j94kk3dd3bbfw6a2l14i7vd4rh11g9lxhw4zsm15vg71cm1lv9"))))
     (properties `((upstream-name . "Gviz")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16708,14 +17109,14 @@ with your data.")
 (define-public r-gwascat
   (package
     (name "r-gwascat")
-    (version "2.28.1")
+    (version "2.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "gwascat" version))
        (sha256
         (base32
-         "19ymdxj8966i4yk0zalfw23938cpv4q7pywg4qb242p44na5y9sl"))))
+         "0sj51cli1p8k7z1nl5rfswjlzrk9cqnpr1a1pr618gk74kfwqf5a"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi
@@ -16742,13 +17143,13 @@ EMBL-EBI GWAS catalog.")
 (define-public r-kegggraph
   (package
     (name "r-kegggraph")
-    (version "1.56.0")
+    (version "1.58.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "KEGGgraph" version))
        (sha256
-        (base32 "15pq040pcg8hr18xixmjp59xb7mgvygjv6kisqk8yv99l1611ndx"))))
+        (base32 "0hpsb009qmhy9p67d5wd0cl60smhgjlhxsz5f52i1c6qy4jk1niq"))))
     (properties `((upstream-name . "KEGGgraph")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16766,14 +17167,14 @@ functionalities including parsing, graph operation, visualization and etc.")
 (define-public r-ldblock
   (package
     (name "r-ldblock")
-    (version "1.26.0")
+    (version "1.28.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ldblock" version))
        (sha256
         (base32
-         "08ss03b93czwb4x60hsi30ad4lmamvq5mxa8nj0g18z68qcraijm"))))
+         "0i8v4wfp207f5dpf3y2n8fqn7mc4khj92gb209vzc3y3kbwp2c6n"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-biocgenerics
@@ -16890,13 +17291,13 @@ other functional sequencing data.")
 (define-public r-pathview
   (package
     (name "r-pathview")
-    (version "1.36.1")
+    (version "1.38.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "pathview" version))
        (sha256
-        (base32 "11g4zhy4qfq0gmy588334f7s2w1acs2dz9kimax5ya2b8jjibk71"))))
+        (base32 "0p7cdq03863zpw009prs1yh3gps1kw135anjfq6wpdkwza7xy4py"))))
     (properties `((upstream-name . "pathview")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16924,14 +17325,14 @@ large-scale and fully automated analysis.")
 (define-public r-snpstats
   (package
     (name "r-snpstats")
-    (version "1.46.0")
+    (version "1.48.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "snpStats" version))
        (sha256
         (base32
-         "0a5b5nqc7n965jk45ijwkzbn416ib4gfhp8xl39z8f2bdskip4a2"))))
+         "14rkrav4iydc85194skdy33sk365pjmmvxxvzaxxh0k9ds009qwx"))))
     (properties `((upstream-name . "snpStats")))
     (build-system r-build-system)
     (inputs (list zlib))
@@ -16948,14 +17349,14 @@ the earlier snpMatrix package, allowing for uncertainty in genotypes.")
 (define-public r-chromstar
   (package
     (name "r-chromstar")
-    (version "1.22.0")
+    (version "1.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "chromstaR" version))
        (sha256
         (base32
-         "1xjwmnr4hk8v3nwvhqd6ixk5qr2dv0n4mb9wd6nl7cgjfhjsdgj7"))))
+         "17p22vsmb9h8ap0f2rzyg2r71srj3sxiapzyaz1csad2vfjxfi2r"))))
     (properties `((upstream-name . "chromstaR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -16986,14 +17387,14 @@ analyses.")
 (define-public r-guitar
   (package
     (name "r-guitar")
-    (version "2.12.0")
+    (version "2.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Guitar" version))
        (sha256
         (base32
-         "09grsasnnk7rmlzjh4lhas9r5spzcsrvmdqj6fx1dk22sckcqahh"))))
+         "0lrw1v82amr54bkfh98953b16fhlgd1i6kz1g7zy8gj0hd417ms1"))))
     (properties `((upstream-name . "Guitar")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17039,14 +17440,14 @@ visualizations for publication-quality multi-panel figures.")
 (define-public r-ballgown
   (package
     (name "r-ballgown")
-    (version "2.28.0")
+    (version "2.30.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "ballgown" version))
        (sha256
         (base32
-         "0l8q3fymskxmsi5jcikzjz5xi66lpzgv7bjymir4izah2v68z708"))))
+         "0iy24vj4lg1k4fzdxf9blc47xsp4dmplajgabsb2s925l7jpxfvw"))))
     (properties `((upstream-name . "ballgown")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17073,14 +17474,14 @@ to annotation.")
 (define-public r-megadepth
   (package
     (name "r-megadepth")
-    (version "1.6.0")
+    (version "1.8.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "megadepth" version))
        (sha256
         (base32
-         "0qq82dmd3drr2bhn51bgbc6ml40klfmmhj6wdj72n9ya6n60lwy8"))))
+         "1krk5iqqzkkkxfgsvi9j6mj14i2rzisrrq0xmxjsrkgfh19awhr8"))))
     (properties `((upstream-name . "megadepth")))
     (build-system r-build-system)
     (inputs (list megadepth))
@@ -17106,14 +17507,14 @@ regions or annotations of your choice from BigWig files.")
 (define-public r-beclear
   (package
     (name "r-beclear")
-    (version "2.12.0")
+    (version "2.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BEclear" version))
        (sha256
         (base32
-         "0x43yfnmb2d782g3g52nqdfs90i3zrrlqz8qy3ybmgv5f8n92p15"))))
+         "05znaj2fialxi937mhj2dlrm3v4j2wgqafcy78qrkz7xxn13pr01"))))
     (properties `((upstream-name . "BEclear")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17122,6 +17523,7 @@ regions or annotations of your choice from BigWig files.")
            r-data-table
            r-dixontest
            r-futile-logger
+           r-ids
            r-matrix
            r-rcpp
            r-rdpack))
@@ -17139,14 +17541,14 @@ real numbers.")
 (define-public r-bgeecall
   (package
     (name "r-bgeecall")
-    (version "1.12.2")
+    (version "1.14.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BgeeCall" version))
        (sha256
         (base32
-         "0l6smwy55mm4clb71l4bpch3bayyyf87nq1asbrv6s6fd22mmwil"))))
+         "05w6b10vc4mmwdqnkcj7vnfigk03f03n776vqhlb38k0lx8k4hk3"))))
     (properties `((upstream-name . "BgeeCall")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17175,14 +17577,14 @@ all RNA-Seq libraries of each species integrated in Bgee.")
 (define-public r-bgeedb
   (package
     (name "r-bgeedb")
-    (version "2.22.3")
+    (version "2.24.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BgeeDB" version))
        (sha256
         (base32
-         "1f6lrazaibbz21sqvj59rq6ps9m1riw2y0kyidbn29mxf4ibwh3k"))))
+         "14fja1dikzq60zjx1arcv1q16qd0hmibqjy0nbaivmk3zh16spkc"))))
     (properties `((upstream-name . "BgeeDB")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17209,14 +17611,14 @@ anatomical terms, mapped to genes by expression patterns.")
 (define-public r-biobtreer
   (package
     (name "r-biobtreer")
-    (version "1.8.0")
+    (version "1.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biobtreeR" version))
        (sha256
         (base32
-         "0cx46hdqqm6mbj0vp4y86axv0qccd4sgk2jwwjvnqp5pynq9bbqa"))))
+         "1j6w19k124x46gj2p8f1z0i2c03yhiiy1w0fqf504b2r7wy90jxc"))))
     (properties `((upstream-name . "biobtreeR")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17233,14 +17635,14 @@ mappings functionalities.")
 (define-public r-minet
   (package
     (name "r-minet")
-    (version "3.54.0")
+    (version "3.56.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "minet" version))
        (sha256
         (base32
-         "0q6jw2jqkl9qynjpzaygz45c7dmx1l5y2d8s1illpcf87siawcam"))))
+         "1xknyc2m03dyqrnx6np2y2lr41w06arl114f6cncl6wsnanqxzrz"))))
     (properties `((upstream-name . "minet")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17255,14 +17657,14 @@ information networks from data.")
 (define-public r-genetclassifier
   (package
     (name "r-genetclassifier")
-    (version "1.36.0")
+    (version "1.38.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "geNetClassifier" version))
        (sha256
         (base32
-         "1kh7mp5h0n7yd1klcd7w4v7i3fh9pkmvgf7189wangfzbcsr4f70"))))
+         "1ahlml1ssjmg126ki1phdprq4v0nawzbbfq8jray5ypaj32qx3r2"))))
     (properties
      `((upstream-name . "geNetClassifier")))
     (build-system r-build-system)
@@ -17280,14 +17682,14 @@ interface to query the classifier.")
 (define-public r-dir-expiry
   (package
     (name "r-dir-expiry")
-    (version "1.4.0")
+    (version "1.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "dir.expiry" version))
        (sha256
         (base32
-         "098wzm8hlpy70c99k2sl4k8z2dllhw7rwdj8dhcskr7kaw71k3sq"))))
+         "1ix31jcfi3dg12pa0sz4k4izwc9rsydy6krl7f949lkam2g7s5f8"))))
     (properties `((upstream-name . "dir.expiry")))
     (build-system r-build-system)
     (propagated-inputs (list r-filelock))
@@ -17304,14 +17706,14 @@ eliminating obsolete caches generated by old versions of packages.")
 (define-public r-basilisk-utils
   (package
     (name "r-basilisk-utils")
-    (version "1.8.0")
+    (version "1.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "basilisk.utils" version))
        (sha256
         (base32
-         "1jnqv0rlljkq27rd4ixl763v335f2aanm4fzr386yc81fj4vnmhk"))))
+         "0gh29w8arg0glawprwshaixv07y756c4lx21h8jjbqlsrbspp8fw"))))
     (properties
      `((upstream-name . "basilisk.utils")))
     (build-system r-build-system)
@@ -17328,14 +17730,14 @@ package, primarily for creation of the underlying Conda instance.")
 (define-public r-basilisk
   (package
     (name "r-basilisk")
-    (version "1.8.1")
+    (version "1.10.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "basilisk" version))
        (sha256
         (base32
-         "134xix2iq5l7783dng2jjklxd3m5lh4snb7bjhslrs2r1j3p8jpk"))))
+         "14sgm3ia7jj5jckysqkljrffafg6rl8i7fgzsxv8ycnrwbd05d09"))))
     (properties `((upstream-name . "basilisk")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17354,14 +17756,14 @@ Python environments in a single R session.")
 (define-public r-biocthis
   (package
     (name "r-biocthis")
-    (version "1.6.0")
+    (version "1.8.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biocthis" version))
        (sha256
         (base32
-         "1hdgjp00d2si3mr7m1d289i9wn7g927z6n8n27d5sm94lb91qln0"))))
+         "0zmiaixknwxv72l4fygrn0qr3mvl7kqfbqgflnavs0wxx6xdjqgn"))))
     (properties `((upstream-name . "biocthis")))
     (build-system r-build-system)
     (arguments
@@ -17388,14 +17790,14 @@ Bioconductor-friendly.")
 (define-public r-biocdockermanager
   (package
     (name "r-biocdockermanager")
-    (version "1.8.1")
+    (version "1.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BiocDockerManager" version))
        (sha256
         (base32
-         "0a4dcga18bw5mvzmsml28bf4zclz32pp9iflnbvps7pdxvhmmg9d"))))
+         "13l5shmiiv4wl9m5xnwzagjxqrchjg9znvcgf7hv8f263l2yc8qm"))))
     (properties
      `((upstream-name . "BiocDockerManager")))
     (build-system r-build-system)
@@ -17418,14 +17820,14 @@ the Bioconductor project.")
 (define-public r-biodb
   (package
     (name "r-biodb")
-    (version "1.4.2")
+    (version "1.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biodb" version))
        (sha256
         (base32
-         "0f3clqmrpaawhjjyb4x5mnbhsam56r0av05b5cl5p4waylp8qbs1"))))
+         "08ahz3v2xbhwfh89dbnhhcdm0x5qv4hibi8wknlqf5x8gqm5j5w6"))))
     (properties `((upstream-name . "biodb")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17463,14 +17865,14 @@ separate published packages.")
 (define-public r-biomformat
   (package
     (name "r-biomformat")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biomformat" version))
        (sha256
         (base32
-         "12wqjipxhngmlnrdmx329dqmkmy2wa4nkkrhwaqv2nwy90dncs9n"))))
+         "0728fpj05bvna5lpm29pdbn4slfmq16nz35as086ddbl2hhc9ni1"))))
     (properties `((upstream-name . "biomformat")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17492,14 +17894,14 @@ as extensions of common core functions/methods.")
 (define-public r-mvcclass
   (package
     (name "r-mvcclass")
-    (version "1.70.0")
+    (version "1.72.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MVCClass" version))
        (sha256
         (base32
-         "0apcjlq4i2mg8mlfqgvlcsqkiy51whzid3nd0m830jff0ywgh47g"))))
+         "1yzb7m7vk50f9x1g8yb95wlmpccj3n4qgczz46lvhsk7hkifybzq"))))
     (properties `((upstream-name . "MVCClass")))
     (build-system r-build-system)
     (home-page "https://bioconductor.org/packages/MVCClass")
@@ -17512,14 +17914,14 @@ design.")
 (define-public r-biomvcclass
   (package
     (name "r-biomvcclass")
-    (version "1.64.0")
+    (version "1.66.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BioMVCClass" version))
        (sha256
         (base32
-         "078pnyygbvbfxziqspfr1nn78w67xyb4qmiwc34czga5psblvfwz"))))
+         "1xclmwxps7yvqnaw8kn6z4mlpx6v8xfzyly4cadsjaj2qm535xxk"))))
     (properties `((upstream-name . "BioMVCClass")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17534,14 +17936,14 @@ design.")
 (define-public r-biomvrcns
   (package
     (name "r-biomvrcns")
-    (version "1.36.0")
+    (version "1.38.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biomvRCNS" version))
        (sha256
         (base32
-         "0i576g7pkivqaxff1pkb760mdpx8v9fh071aic1mwfnlfa7k87ln"))))
+         "0n026b744ah5kcnipsyiqqs7vlz5n5im1kgv35i2pgxyzvf7a8sn"))))
     (properties `((upstream-name . "biomvRCNS")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17559,14 +17961,14 @@ using aCGH or sequencing.")
 (define-public r-bionero
   (package
     (name "r-bionero")
-    (version "1.4.2")
+    (version "1.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BioNERO" version))
        (sha256
         (base32
-         "0dsznfnhidbmf52rv8l26f1ms2k9yy4q4c6cf3x8ylc79c1sjrcp"))))
+         "10nwgp8a9chn33p5k7cdp920rraiw187xfrylyd9bq010c7vp7xh"))))
     (properties `((upstream-name . "BioNERO")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17615,14 +18017,14 @@ networks.")
 (define-public r-bionet
   (package
     (name "r-bionet")
-    (version "1.56.0")
+    (version "1.58.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BioNet" version))
        (sha256
         (base32
-         "0kcw71j4nmdkn373wk21ak6h0v4gycivnfrklb72kk1qcmsy1wrm"))))
+         "12c6m7dzwkdh4bk1c5xmzm5ajrsba7v62mag1f3rrpmrapdh6s0j"))))
     (properties `((upstream-name . "BioNet")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17644,14 +18046,14 @@ scoring subnetwork.")
 (define-public r-bionetstat
   (package
     (name "r-bionetstat")
-    (version "1.16.1")
+    (version "1.18.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BioNetStat" version))
        (sha256
         (base32
-         "0zs6pymvxb95sji0rnnzaz3whj7hsvj2kl4n4gzj7w1q0prbfpb2"))))
+         "1h99d6gnqw5v9ha2169zfhw9cvxhyjgkf4zm8qj1i03h2cywapgv"))))
     (properties `((upstream-name . "BioNetStat")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17686,14 +18088,14 @@ network and metabolic pathways view.")
 (define-public r-bioqc
   (package
     (name "r-bioqc")
-    (version "1.24.0")
+    (version "1.26.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BioQC" version))
        (sha256
         (base32
-         "0vb2nnzqvyv25pw8qshcmijravswafg0858pkgqjgiv7wsr2mn3m"))))
+         "1ssxsxdm8vmlrmvvdz5p98apd3xsal1h3ss8556g83kgw830zsxf"))))
     (properties `((upstream-name . "BioQC")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17712,14 +18114,14 @@ optimised for high performance.")
 (define-public r-biotip
   (package
     (name "r-biotip")
-    (version "1.10.0")
+    (version "1.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "BioTIP" version))
        (sha256
         (base32
-         "1sihi5zy7mlabh3ix1wvdqz8ibfq1avl8bnxjhvxyzq40zbcklh6"))))
+         "1n90n4vz0cwz8irwpmrkm9qcyvk5rssl2v6wrzny4zwhzjkmvlni"))))
     (properties `((upstream-name . "BioTIP")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17742,14 +18144,14 @@ help unravel disease regulatory trajectory.")
 (define-public r-biotmle
   (package
     (name "r-biotmle")
-    (version "1.20.0")
+    (version "1.22.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biotmle" version))
        (sha256
         (base32
-         "1frig90krvfdk6nwpmslpj0pvligyzwzfwwci7hzwcmbglk5jj22"))))
+         "1sbwbz0xdws31lsh46mfcijqmi6rm050r1d6vwii65q686x5j43w"))))
     (properties `((upstream-name . "biotmle")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17784,14 +18186,14 @@ ensemble machine learning for the estimation of nuisance functions.")
 (define-public r-bsseq
   (package
     (name "r-bsseq")
-    (version "1.32.0")
+    (version "1.34.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "bsseq" version))
        (sha256
         (base32
-         "1jpfib2vb6hd7pgh3d33jgch24lba175zmbalwsbgvlmmyyf1ki5"))))
+         "0rd0ihr1ai1kvly2zf5y2qx3qyhk3ag2mdsrwqnzs67xkv99glsf"))))
     (properties `((upstream-name . "bsseq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17830,13 +18232,13 @@ visualizing bisulfite sequencing data.")
 (define-public r-dada2
   (package
     (name "r-dada2")
-    (version "1.24.0")
+    (version "1.26.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "dada2" version))
               (sha256
                (base32
-                "0nvjnmcjh0i660y8s3rh9b3zl163wxdx7qm2n36m6vf0iy987l4x"))))
+                "1cdfq4qa4kkfkqnkyxyr109hbvj5li396rm3p2b11qm2pxmfd7kc"))))
     (properties `((upstream-name . "dada2")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17867,14 +18269,14 @@ fragments by exact matching.")
 (define-public r-dmrseq
   (package
     (name "r-dmrseq")
-    (version "1.16.0")
+    (version "1.18.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "dmrseq" version))
        (sha256
         (base32
-         "1c99l62fi26bnbvpzrlsvvs722za0l5vfhddcrhzzzasabhccb4n"))))
+         "1zx62lbj0am85p0c1vk06s7qf8294vk8yyh67nkiqc7xgqqwybyk"))))
     (properties `((upstream-name . "dmrseq")))
     (build-system r-build-system)
     (propagated-inputs
@@ -17913,13 +18315,13 @@ interest on transformed methylation proportions.")
 (define-public r-omicade4
   (package
     (name "r-omicade4")
-    (version "1.36.0")
+    (version "1.38.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "omicade4" version))
               (sha256
                (base32
-                "1l7w3sczsimg640klq8navgdcwjj090wjqd40n4mw76pny2xj2lj"))))
+                "1w9fsg0r6ir9nmmpf08b1mh8mnrzxk3f398y1w5dg34fdz4phgpg"))))
     (properties `((upstream-name . "omicade4")))
     (build-system r-build-system)
     (propagated-inputs (list r-ade4 r-biobase r-made4))
@@ -17932,13 +18334,13 @@ interest on transformed methylation proportions.")
 (define-public r-omnipathr
   (package
     (name "r-omnipathr")
-    (version "3.4.0")
+    (version "3.5.25")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "OmnipathR" version))
        (sha256
-        (base32 "0vk0fv09j3ql78mzzhdxwxb2b83qqdz2qfd8wpp1vydmcx2vvgni"))))
+        (base32 "1a0d4vf8i45h1fifswx9lhk6fk0z8sxfnav35psz9kvmxxab9698"))))
     (properties `((upstream-name . "OmnipathR")))
     (build-system r-build-system)
     (arguments
@@ -17958,12 +18360,14 @@ interest on transformed methylation proportions.")
            r-later
            r-logger
            r-magrittr
+           r-rmarkdown
            r-progress
            r-purrr
            r-rappdirs
            r-readr
            r-readxl
            r-rlang
+           r-rvest
            r-stringr
            r-tibble
            r-tidyr
@@ -17985,14 +18389,14 @@ for ligand activity prediction from transcriptomics data.")
 (define-public r-biscuiteer
   (package
     (name "r-biscuiteer")
-    (version "1.10.0")
+    (version "1.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "biscuiteer" version))
        (sha256
         (base32
-         "0y7vbdaafiga16yr0d22w1v4p0jmczndcar0r0km06f5y1b74amr"))))
+         "1fq2nj0vclpxavqj5qx7jc3ympg00izxn9fpy4mlhyp9l921z13m"))))
     (properties `((upstream-name . "biscuiteer")))
     (build-system r-build-system)
     (propagated-inputs
@@ -18037,13 +18441,13 @@ estimates, etc.")
 (define-public r-tcgabiolinks
   (package
     (name "r-tcgabiolinks")
-    (version "2.24.3")
+    (version "2.25.3")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "TCGAbiolinks" version))
        (sha256
-        (base32 "0visvfhzaf0p1rb5vjkmw1c91zfxpks8nl9nbl9xlnpm8lkmmkms"))))
+        (base32 "0daq7093yipry8pp6fj6pj8x1njxs8j6cz7875qkfmzqkbis4vql"))))
     (properties `((upstream-name . "TCGAbiolinks")))
     (build-system r-build-system)
     (propagated-inputs
@@ -18092,13 +18496,13 @@ starburst plots) in order to easily develop complete analysis pipelines.")
 (define-public r-tricycle
   (package
     (name "r-tricycle")
-    (version "1.4.0")
+    (version "1.6.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "tricycle" version))
               (sha256
                (base32
-                "0bjkajcz6xcfak6071d0ihakrvgf7s0pmkn6vqkjd6yxbfld7zln"))))
+                "0b5agqhywg23zxf0f9s1vfbzs7s7ijf9c716s7hwjprxfdz5znvw"))))
     (properties `((upstream-name . "tricycle")))
     (build-system r-build-system)
     (propagated-inputs
@@ -18131,14 +18535,14 @@ embeddings and functions to build new reference.")
 (define-public r-tximeta
   (package
     (name "r-tximeta")
-    (version "1.14.1")
+    (version "1.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "tximeta" version))
        (sha256
         (base32
-         "0hxq5lkrdiz0a3xpl88adrv4m55jr6g46a5m9pamc0w4bxddirr8"))))
+         "0v1s5ssinyrizpg2i88dn2ckzs4i16hjfg2pzxhal3ypsiw24qna"))))
     (properties `((upstream-name . "tximeta")))
     (build-system r-build-system)
     (propagated-inputs
@@ -18172,13 +18576,13 @@ reproducibility.")
 (define-public r-phyloseq
   (package
     (name "r-phyloseq")
-    (version "1.40.0")
+    (version "1.42.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "phyloseq" version))
        (sha256
-        (base32 "0hcyv4ziyaw74mc9vf7bad3q9izi9p0whg3hspbs6w8b3hp34y2k"))))
+        (base32 "07zi059v6zwrm31qwc7fmg35fwqlqfb6c30wwj9q4m2y67srnskk"))))
     (properties `((upstream-name . "phyloseq")))
     (build-system r-build-system)
     (propagated-inputs
diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 6d7097c42c..6c6ff3e25a 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -23,6 +23,7 @@
 ;;; Copyright © 2021 Hong Li <hli@mdc-berlin.de>
 ;;; Copyright © 2021, 2022 Simon Tournier <zimon.toutoune@gmail.com>
 ;;; Copyright © 2021 Felix Gruber <felgru@posteo.net>
+;;; Copyright © 2022 Navid Afkhami <navid.afkhami@mdc-berlin.de>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -535,6 +536,42 @@ BED, GFF/GTF, VCF.")
 and utilities for PacBio C++ applications.")
       (license license:bsd-3))))
 
+(define-public r-btools
+  (let ((commit "fa21d4ca01d37ea4d98b45582453f3bf95cbc2b5")
+        (revision "1"))
+    (package
+      (name "r-btools")
+      (version (git-version "0.0.1" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://github.com/twbattaglia/btools")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "0bca593dnxz6xdywpdi0ipli0paln2b3bfxxj0csnmj55ryrz428"))))
+      (properties `((upstream-name . "btools")))
+      (build-system r-build-system)
+      (propagated-inputs
+       (list r-biomformat
+             r-coin
+             r-deseq2
+             r-dplyr
+             r-genefilter
+             r-phyloseq
+             r-picante
+             r-plotly
+             r-reshape2
+             r-stringr
+             r-vegan))
+      (home-page "https://github.com/twbattaglia/btools")
+      (synopsis "R functions for microbial diversity analyses")
+      (description
+       "This package provides an assortment of R functions that is suitable
+for all types of microbial diversity analyses.")
+      (license license:expat))))
+
 (define-public pbbam
   (package
     (name "pbbam")
diff --git a/gnu/packages/bqn.scm b/gnu/packages/bqn.scm
index 984dfbe53e..d295019489 100644
--- a/gnu/packages/bqn.scm
+++ b/gnu/packages/bqn.scm
@@ -113,7 +113,7 @@ the same author.")
   ;; Aside from dbqn above, the main bqn repository is used by other
   ;; implementations as a "known good" set of sources. CBQN uses dbqn to
   ;; generate an intermediate bytecode for its own compilation.
-    (let ((commit "e219af48401473a7bac49bdd8b89d69082cf5dd8"))
+    (let ((commit "71ce36141aaacfa714edca2e408ca522a3bc5554"))
       (origin
         (method git-fetch)
         (uri (git-reference
@@ -121,11 +121,11 @@ the same author.")
               (commit commit)))
         (file-name (git-file-name "bqn-sources" commit))
         (sha256
-         (base32 "0r6pa9lscl2395g4xlvmg90vpdsjzhin4f1r0s7brymmpvmns2yc")))))
+         (base32 "060a3r5m7hynzxj4iz1av2kj5jf8w3j8yswzzx9wkx31rdrsiv2c")))))
 
 (define cbqn-bootstrap
-  (let* ((revision "1")
-         (commit "9c1cbdc99863b1da0116df61cd832137b196dc5c"))
+  (let* ((revision "2")
+         (commit "66584ce1491d300746963b8ed17170348b2a03e6"))
     (package
       (name "cbqn-bootstrap")
       (version (git-version "0" revision commit))
@@ -137,7 +137,7 @@ the same author.")
                 (file-name (git-file-name name version))
                 (sha256
                  (base32
-                  "0w38fhwf20drkyijy6nfnhmc5g5gw0zmzgmy1q605x57znlj85a2"))))
+                  "13gg96aa56b8k08bjvv8i0f5nxrah2sij7g6pg7i21fdv08rd9iv"))))
       (build-system gnu-build-system)
       (arguments
        (list
diff --git a/gnu/packages/calendar.scm b/gnu/packages/calendar.scm
index 9328c1c1a6..cf4286100d 100644
--- a/gnu/packages/calendar.scm
+++ b/gnu/packages/calendar.scm
@@ -34,6 +34,7 @@
   #:use-module (guix packages)
   #:use-module (guix download)
   #:use-module (guix build-system gnu)
+  #:use-module (guix build-system go)
   #:use-module (guix build-system cmake)
   #:use-module (guix build-system python)
   #:use-module (gnu packages admin)
@@ -45,6 +46,7 @@
   #:use-module (gnu packages freedesktop)
   #:use-module (gnu packages glib)
   #:use-module (gnu packages gnome)
+  #:use-module (gnu packages golang)
   #:use-module (gnu packages gtk)
   #:use-module (gnu packages icu4c)
   #:use-module (gnu packages perl)
@@ -426,3 +428,38 @@ written in C++ using GTK.  Launched once, it pops up a small calendar applet,
 launched again it closes the running instance.  It can additionally be
 configured to show the current time in different timezones.")
       (license license:bsd-3))))
+
+(define-public hebcal
+  (let ((commit "2384bb88dc1a41a4a5ae57a29fb58b2dd49a475d")
+        (revision "0"))
+    (package
+      (name "hebcal")
+      (version (git-version "5.3.0" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://github.com/hebcal/hebcal")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "12rv3b51jb7wcjwmmizz9jkw7gh37yklys4xncvpzgxdkkfgmmjx"))))
+      (build-system go-build-system)
+      (arguments
+       (list #:import-path "github.com/hebcal/hebcal"))
+      (inputs
+       (list go-github-com-hebcal-hebcal-go
+             go-github-com-pborman-getopt))
+      (synopsis "Perpetual Jewish Calendar program")
+      (description
+       "Hebcal is a program for converting between Hebrew and Gregorian
+dates, and generating lists of Jewish holidays for a given year.
+Shabbat, holiday candle lighting, and havdalah times are approximated
+using your location.
+
+It can also show daily prayer times, the weekly Torah reading, and
+the daily leaf of Talmud.  The program can help with counting of the
+Omer or with calculation of Hebrew yahrzeits, birthdays, or
+anniversaries.")
+      (home-page "https://github.com/hebcal/hebcal")
+      (license license:gpl2+))))
diff --git a/gnu/packages/ci.scm b/gnu/packages/ci.scm
index fb4e48ad4d..b78e8b739b 100644
--- a/gnu/packages/ci.scm
+++ b/gnu/packages/ci.scm
@@ -58,8 +58,8 @@
   #:use-module ((guix search-paths) #:select ($SSL_CERT_DIR)))
 
 (define-public cuirass
-  (let ((commit "1fb4b0ac1297e9bd680d0f4a356ce3050b27f913")
-        (revision "12"))
+  (let ((commit "1341725f2cbb886e0960c6fad13444e3cfe36c13")
+        (revision "13"))
     (package
       (name "cuirass")
       (version (git-version "1.1.0" revision commit))
@@ -72,7 +72,7 @@
          (file-name (git-file-name name version))
          (sha256
           (base32
-           "0134klqiykjgyc6lwl165hpil6hgd8xhm62mpxabr6wrvclk8bhm"))))
+           "0l928hd84ky9l4d1nfdkzc4jvghvxia4j6gflliydvfiyfiw87b3"))))
       (build-system gnu-build-system)
       (arguments
        `(#:modules ((guix build utils)
diff --git a/gnu/packages/cluster.scm b/gnu/packages/cluster.scm
index 6e4055736a..4db64d5d19 100644
--- a/gnu/packages/cluster.scm
+++ b/gnu/packages/cluster.scm
@@ -132,7 +132,7 @@
            ;; For the documentation.
            docbook-xml
            docbook-xml-4.4              ;used by documentation/ra2refentry.xsl
-           docbook-xsl
+           docbook-xsl-next
            libxml2                      ;for XML_CATALOG_FILES
            libxslt                      ;for xsltproc
            ruby-asciidoctor))
diff --git a/gnu/packages/cran.scm b/gnu/packages/cran.scm
index 3e5d654c5a..ad0657ef3b 100644
--- a/gnu/packages/cran.scm
+++ b/gnu/packages/cran.scm
@@ -599,6 +599,27 @@ Google.  @code{googleVis} makes use of the internal R HTTP server to display
 the output locally.")
     (license license:gpl2+)))
 
+(define-public r-gson
+  (package
+    (name "r-gson")
+    (version "0.0.9")
+    (source (origin
+              (method url-fetch)
+              (uri (cran-uri "gson" version))
+              (sha256
+               (base32
+                "065ify3i7zqwi7h5jzr7kdgr358kwgw6xrkvvmrznbl7s9f7d57n"))))
+    (properties `((upstream-name . "gson")))
+    (build-system r-build-system)
+    (propagated-inputs (list r-jsonlite r-rlang r-tidyr))
+    (home-page "https://cran.r-project.org/package=gson")
+    (synopsis "Base Class and Methods for 'gson' Format")
+    (description
+     "This packages proposes a new file format named @code{gson} for storing
+gene set and related information, and provides read, write and other utilities
+to process this file format.")
+    (license license:artistic2.0)))
+
 (define-public r-guix-install
   (package
     (name "r-guix-install")
@@ -709,6 +730,33 @@ allows transformation of geographic coordinates from one projection and/or
 datum to another.")
     (license license:gpl2)))
 
+(define-public r-rorcid
+  (package
+    (name "r-rorcid")
+    (version "0.7.0")
+    (source (origin
+              (method url-fetch)
+              (uri (cran-uri "rorcid" version))
+              (sha256
+               (base32
+                "1d0s5w48ksyj152nc4xq5w0nsimab8jc5fgspdwnbas2g8a52igr"))))
+    (properties `((upstream-name . "rorcid")))
+    (build-system r-build-system)
+    (propagated-inputs (list r-crul
+                             r-data-table
+                             r-fauxpas
+                             r-httr
+                             r-jsonlite
+                             r-tibble
+                             r-xml2))
+    (home-page "https://github.com/ropensci/rorcid")
+    (synopsis "Interface to the @url{Orcid.org, https://orcid.org} API")
+    (description
+     "This package provides an API for @url{Orcid.org, https://orcid.org}.
+Functions include searching for people, searching by DOI, or searching by
+Orcid ID.")
+    (license license:expat)))
+
 (define-public r-waldo
   (package
     (name "r-waldo")
@@ -1273,13 +1321,13 @@ variables.")
 (define-public r-ggprism
   (package
     (name "r-ggprism")
-    (version "1.0.3")
+    (version "1.0.4")
     (source (origin
               (method url-fetch)
               (uri (cran-uri "ggprism" version))
               (sha256
                (base32
-                "09dh0r8r5s61i5dbk6rswajc2vm7k8wvlqyvzq8wr160676lycjp"))))
+                "0ycklp7764cw65hqh9r61im8vqfd7sjayyw1gvprxzg7k217gnl3"))))
     (properties `((upstream-name . "ggprism")))
     (build-system r-build-system)
     (propagated-inputs
@@ -1874,6 +1922,30 @@ excellent candidate for labeling of a polygon.")
 @code{dplyr} and the wider @code{tidyverse} using only @code{base}.")
     (license license:expat)))
 
+(define-public r-ecosolver
+  (package
+    (name "r-ecosolver")
+    (version "0.5.4")
+    (source (origin
+              (method url-fetch)
+              (uri (cran-uri "ECOSolveR" version))
+              (sha256
+               (base32
+                "0973m346vakgddp92dzqlky0wa196hj341r9y7rz67bc2zl8jx2x"))))
+    (properties `((upstream-name . "ECOSolveR")))
+    (build-system r-build-system)
+    (native-inputs (list r-knitr))
+    (home-page "https://bnaras.github.io/ECOSolveR/")
+    (synopsis "Embedded conic solver in R")
+    (description
+     "This package provides an R interface to the @dfn{Embedded COnic
+Solver} (ECOS), an efficient and robust C library for convex problems.
+Conic and equality constraints can be specified in addition to integer
+and boolean variable constraints for mixed-integer problems.  This R
+interface is inspired by the Python interface and has similar calling
+conventions.")
+    (license license:gpl3+)))
+
 (define-public r-ecp
   (package
     (name "r-ecp")
@@ -3603,13 +3675,13 @@ annotation data to keep updated.")
 (define-public r-ggtern
   (package
     (name "r-ggtern")
-    (version "3.3.5")
+    (version "3.4.0")
     (source
      (origin
        (method url-fetch)
        (uri (cran-uri "ggtern" version))
        (sha256
-        (base32 "15hhn8msy0l8zbq8ms0zvg1iajn1c28gd77v3hp6dvwwsla8zzbd"))))
+        (base32 "01j1rvff3vz72vwqsy3bh81aav7gfymg4sbvc267vg0r3a16ywcg"))))
     (properties `((upstream-name . "ggtern")))
     (build-system r-build-system)
     (propagated-inputs
@@ -5639,6 +5711,43 @@ testing framework of Wald are generic and can therefore also be used in other
 contexts.")
     (license license:gpl2+)))
 
+(define-public r-cvxr
+  (package
+    (name "r-cvxr")
+    (version "1.0-11")
+    (source (origin
+              (method url-fetch)
+              (uri (cran-uri "CVXR" version))
+              (sha256
+               (base32
+                "0alp1g4bszxqcrjbn54bz1zswg8y10372fwwlbi0jjazycw9cap9"))))
+    (properties `((upstream-name . "CVXR")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-bit64
+           r-ecosolver
+           r-gmp
+           r-matrix
+           r-osqp
+           r-r6
+           r-rcpp
+           r-rcppeigen
+           r-rmpfr
+           r-scs))
+    (native-inputs (list r-knitr))
+    (home-page "https://cvxr.rbind.io")
+    (synopsis "Disciplined convex optimization")
+    (description
+     "This package provides an object-oriented modeling language for
+@dfn{disciplined convex programming} (DCP) as described in Fu,
+Narasimhan, and Boyd (2020, <doi:10.18637/jss.v094.i14>).  It allows
+the user to formulate convex optimization problems in a natural way
+following mathematical convention and DCP rules.  The system analyzes
+the problem, verifies its convexity, converts it into a canonical
+form, and hands it off to an appropriate solver to obtain the
+solution.  Interfaces to solvers on CRAN and elsewhere are provided.")
+    (license license:asl2.0)))
+
 (define-public r-squarem
   (package
     (name "r-squarem")
@@ -19203,6 +19312,28 @@ authoring books and technical documents with R Markdown.")
 that accept short and long options.")
     (license license:gpl2+)))
 
+(define-public r-osqp
+  (package
+    (name "r-osqp")
+    (version "0.6.0.7")
+    (source (origin
+              (method url-fetch)
+              (uri (cran-uri "osqp" version))
+              (sha256
+               (base32
+                "00w2hr0pagnvpsk84z99c7alhv7xvs9wpcmkzbcg3qs14g888rgf"))))
+    (properties `((upstream-name . "osqp")))
+    (build-system r-build-system)
+    (propagated-inputs (list r-matrix r-r6 r-rcpp))
+    (home-page "https://osqp.org")
+    (synopsis "Quadratic Programming Solver using the OSQP Library")
+    (description
+     "This package provides bindings to the OSQP solver.  The OSQP
+solver is a numerical optimization package or solving convex quadratic
+programs written in C and based on the alternating direction method of
+multipliers.  See <arXiv:1711.08013> for details.")
+    (license (list license:asl2.0))))
+
 (define-public r-kernlab
   (package
     (name "r-kernlab")
@@ -20947,6 +21078,30 @@ errors and possible semantic issues.  It supports on the fly checking of R
 code edited with @code{RStudio IDE}, @code{Emacs} and @code{Vim}.")
     (license license:expat)))
 
+(define-public r-scs
+  (package
+    (name "r-scs")
+    (version "3.0-1")
+    (source (origin
+              (method url-fetch)
+              (uri (cran-uri "scs" version))
+              (sha256
+               (base32
+                "04srf33zw4dxv22b1h5qwjch5yg7hrvk4iq8yvxqnbr8qzp1x26n"))))
+    (properties `((upstream-name . "scs")))
+    (build-system r-build-system)
+    (home-page "https://github.com/FlorianSchwendinger/scs")
+    (synopsis "Splitting conic solver")
+    (description
+     "This package solves convex cone programs via operator splitting.
+It can solve: linear programs, second-order cone programs,
+semidefinite programs, exponential cone programs, and power cone
+programs, or problems with any combination of those cones.  SCS uses
+AMD (a set of routines for permuting sparse matrices prior to
+factorization) and LDL (a sparse LDL factorization and solve package)
+from SuiteSparse.")
+    (license license:gpl3)))
+
 (define-public r-sctransform
   (package
     (name "r-sctransform")
diff --git a/gnu/packages/databases.scm b/gnu/packages/databases.scm
index e498c5df76..2c87ea8b01 100644
--- a/gnu/packages/databases.scm
+++ b/gnu/packages/databases.scm
@@ -1580,17 +1580,24 @@ types are supported, as is encryption.")
               (sha256
                (base32
                 "1w1q6kh567fd8xismq9i6wr1y893lypd30l452yvydi1qjiq1n6x"))
-              (snippet '(begin (delete-file "rec-mode.info")))))
+              (snippet #~(begin (delete-file "rec-mode.info")))))
     (build-system emacs-build-system)
     (arguments
-     '(#:phases
-       (modify-phases %standard-phases
-         (add-before 'install 'make-info
-           (lambda _
-             (invoke "makeinfo" "--no-split"
-                     "-o" "rec-mode.info" "rec-mode.texi"))))))
-    (native-inputs
-     (list texinfo))
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'patch-program-paths
+            (lambda* (#:key inputs #:allow-other-keys)
+              (emacs-substitute-variables "rec-mode.el"
+                ("rec-recfix" (search-input-file inputs "bin/recfix"))
+                ("rec-recinf" (search-input-file inputs "bin/recinf"))
+                ("rec-recsel" (search-input-file inputs "bin/recsel")))))
+          (add-before 'install 'make-info
+            (lambda _
+              (invoke "makeinfo" "--no-split"
+                      "-o" "rec-mode.info" "rec-mode.texi"))))))
+    (inputs (list recutils))
+    (native-inputs (list texinfo))
     (home-page "https://www.gnu.org/software/recutils/")
     (synopsis "Emacs mode for working with recutils database files")
     (description "This package provides an Emacs major mode @code{rec-mode}
diff --git a/gnu/packages/debug.scm b/gnu/packages/debug.scm
index 0c7f97b386..e69d1ce83b 100644
--- a/gnu/packages/debug.scm
+++ b/gnu/packages/debug.scm
@@ -597,7 +597,7 @@ the position of the variable and allows you to modify its value.")
 (define-public remake
   (package (inherit gnu-make)
     (name "remake")
-    (version "4.3-1.5")
+    (version "4.3-1.6")
     (source (origin
               (method url-fetch)
               (uri (let ((upstream-version
@@ -609,7 +609,7 @@ the position of the variable and allows you to modify its value.")
               (file-name (string-append "remake-" version ".tar.gz"))
               (sha256
                (base32
-                "0xlx2485y0israv2pfghmv74lxcv9i5y65agy69mif76yc4vfvif"))
+                "11vvch8bi0yhjfz7gn92b3xmmm0cgi3qfiyhbnnj89frkhbwd87n"))
               (patches (search-patches "remake-impure-dirs.patch"))))
     (inputs
      (modify-inputs (package-inputs gnu-make)
diff --git a/gnu/packages/disk.scm b/gnu/packages/disk.scm
index 0853eb6d28..8912bb74bc 100644
--- a/gnu/packages/disk.scm
+++ b/gnu/packages/disk.scm
@@ -24,6 +24,7 @@
 ;;; Copyright © 2021 Justin Veilleux <terramorpha@cock.li>
 ;;; Copyright © 2014, 2022 Ludovic Courtès <ludo@gnu.org>
 ;;; Copyright © 2022 Maxim Cournoyer <maxim.cournoyer@gmail.com>
+;;; Copyright © 2022 Disseminate Dissent <disseminatedissent@protonmail.com>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -835,6 +836,46 @@ hierarchy.  It ships with @code{rifle}, a file launcher that is good at
 automatically finding out which program to use for what file type.")
     (license license:gpl3)))
 
+(define-public fff
+  (package
+   (name "fff")
+   (version "2.2")
+   (source (origin
+            (method git-fetch)
+            (uri (git-reference
+                  (url "https://github.com/dylanaraps/fff")
+                  (commit version)))
+            (file-name (git-file-name name version))
+            (sha256
+             (base32
+              "14ymdw6l6phnil0xf1frd5kgznaiwppcic0v4hb61s1zpf4wrshg"))))
+   (build-system gnu-build-system)
+   (inputs
+    (list bash
+          file))
+   (arguments
+    (list
+     #:tests? #f                       ; no tests
+     #:make-flags
+     #~(list
+        (string-append "PREFIX=" #$output))
+     #:phases
+     #~(modify-phases %standard-phases
+         (add-after 'unpack 'refer-to-inputs
+           (lambda* (#:key inputs #:allow-other-keys)
+             (let ((file (assoc-ref inputs "file")))
+               (substitute* "fff"
+                 (("\\bfile [-\"]" match)
+                  (string-append file "/bin/" match))))))
+         (delete 'configure))))         ; no configure script
+   (home-page "https://github.com/dylanaraps/fff")
+   (synopsis "Simple file manager written in bash")
+   (description
+    "@command{fff} (fast file-manager) is a simple, blazing fast and minimal
+file manager for Linux, written in bash.  It only requires bash and coreutils,
+and its highly optimized now for efficient performance.")
+   (license license:expat)))
+
 (define-public volume-key
   (package
     (name "volume-key")
diff --git a/gnu/packages/dns.scm b/gnu/packages/dns.scm
index ce184aa8dd..21b711d147 100644
--- a/gnu/packages/dns.scm
+++ b/gnu/packages/dns.scm
@@ -1013,14 +1013,14 @@ synthesis, and on-the-fly re-configuration.")
 (define-public knot-resolver
   (package
     (name "knot-resolver")
-    (version "5.4.4")
+    (version "5.5.3")
     (source (origin
               (method url-fetch)
               (uri (string-append "https://secure.nic.cz/files/knot-resolver/"
                                   "knot-resolver-" version ".tar.xz"))
               (sha256
                (base32
-                "1sic5ccbbqml4c01dbikkg6qx1gg81nqi76cj79pjdllkqqn92aq"))))
+                "0bgdbx66dsfik3sdqi4g2imddalqc1p41n444xk7s8vxig35g3x3"))))
     (build-system meson-build-system)
     (outputs '("out" "doc"))
     (arguments
diff --git a/gnu/packages/docker.scm b/gnu/packages/docker.scm
index 184280b38f..7d109dc94c 100644
--- a/gnu/packages/docker.scm
+++ b/gnu/packages/docker.scm
@@ -580,7 +580,7 @@ runcexecutor/executor.go"
            util-linux
            lvm2
            tini
-           xfsprogs
+           xfsprogs-5.9
            xz))
     (native-inputs
      (list eudev ; TODO: Should be propagated by lvm2 (.pc -> .pc)
diff --git a/gnu/packages/education.scm b/gnu/packages/education.scm
index 3861c363e7..c0f7778c1c 100644
--- a/gnu/packages/education.scm
+++ b/gnu/packages/education.scm
@@ -667,7 +667,6 @@ language and very flexible regarding to new or unknown keyboard layouts.")
            ki18n
            kiconthemes
            kitemviews
-           kqtquickcharts
            ktextwidgets
            kwidgetsaddons
            kwindowsystem
diff --git a/gnu/packages/emacs-xyz.scm b/gnu/packages/emacs-xyz.scm
index 5c1138e954..8eb4dab077 100644
--- a/gnu/packages/emacs-xyz.scm
+++ b/gnu/packages/emacs-xyz.scm
@@ -554,6 +554,52 @@ optional baked-in Evil support, antialiased separators, and an easy
 configuration language which makes it trivial to write your own themes.")
       (license license:gpl3+))))
 
+(define-public emacs-inspector
+  (let ((commit "0e89d28558f57db4519f154bb72ce617a8c6265d")
+        (revision "0"))
+    (package
+      (name "emacs-inspector")
+      (version (git-version "0.8" revision commit))
+      (source
+       (origin
+         (uri (git-reference
+               (url "https://github.com/mmontone/emacs-inspector")
+               (commit commit)))
+         (method git-fetch)
+         (sha256
+          (base32 "0n72sqn29b5sya686cicgp40mkk5x5821b7bw4zs6dcl82cyij5n"))
+         (file-name (git-file-name name version))))
+      (build-system emacs-build-system)
+      (arguments
+       (list
+        #:tests? #t
+        #:test-command #~(list "emacs" "-Q" "--batch"
+                               "-L" "."
+                               "-l" "inspector-tests.el"
+                               "-l" "tree-inspector-tests.el"
+                               "-f" "ert-run-tests-batch-and-exit")
+        #:phases
+        #~(modify-phases %standard-phases
+            (add-after 'unpack 'preserve-emacs-28-compatibility
+              ;; XXX: `cl-constantly' function is defined in "cl-lib" starting
+              ;; from Emacs 29+.  For now, replace it with its definition.
+              (lambda _
+                (substitute* "tree-inspector.el"
+                  (("cl-constantly") "lambda (_)"))))
+            (add-before 'check 'skip-failing-test
+              (lambda _
+                (substitute* "tree-inspector-tests.el"
+                  (("\\(ert-deftest inspector-tests--inspect-struct-test.*" all)
+                   (string-append all " (skip-unless nil)"))))))))
+      (native-inputs (list emacs-ert-runner))
+      (propagated-inputs (list emacs-treeview))
+      (home-page "https://github.com/mmontone/emacs-inspector")
+      (synopsis "Inspection tool for Emacs Lisp objects")
+      (description
+       "This package provides an introspection tool similar to those found in
+Common Lisp or Smalltalk, but for Emacs Lisp.")
+      (license license:gpl3+))))
+
 (define-public emacs-terminal-here
   (package
     (name "emacs-terminal-here")
@@ -576,6 +622,28 @@ Emacs, whose initial working directories are determined in relation to the
 current buffer.")
     (license license:gpl3+)))
 
+(define-public emacs-treeview
+  (let ((commit "d9c10feddf3b959e7b33ce83103e1f0a61162723")
+        (revision "0"))
+    (package
+      (name "emacs-treeview")
+      (version (git-version "1.1.1" revision commit))
+      (source
+       (origin
+         (uri (git-reference
+               (url "https://github.com/tilmanrassy/emacs-treeview")
+               (commit commit)))
+         (method git-fetch)
+         (sha256
+          (base32 "14s0b6zbapsvgyxki59lglwb3s8wjsjwkgj5r66af9nj2bgz5ms9"))
+         (file-name (git-file-name name version))))
+      (build-system emacs-build-system)
+      (home-page "https://github.com/tilmanrassy/emacs-treeview/")
+      (synopsis "Emacs Lisp framework for tree navigation")
+      (description
+       "Abstract Emacs Lisp framework for tree navigation.")
+      (license license:gpl3+))))
+
 (define-public emacs-hgignore-mode
   ;; From 2021-03-14.
   ;; No releases available.
@@ -741,36 +809,31 @@ Emacs package archive}.")
     (license license:gpl3+)))
 
 (define-public emacs-paredit
-  ;; The last tagged release is from 2014; use the latest commit, which
-  ;; includes many fixes such as honoring the 'fill-paragraph-function'
-  ;; variable.
-  (let ((commit "d0b1a2f42fb47efc8392763d6487fd027e3a2955")
-        (revision "1"))
-    (package
-      (name "emacs-paredit")
-      (version (git-version "24" revision commit))
-      (source (origin
-                (method git-fetch)
-                (uri (git-reference
-                      (url "https://mumble.net/~campbell/git/paredit.git")
-                      (commit commit)))
-                (file-name (git-file-name name version))
-                (sha256
-                 (base32
-                  "1x91xxvwb3r3h61ff1kknlaakxm1a40r7zg2lck9j52yiza4f191"))))
-      (build-system emacs-build-system)
-      (home-page "http://mumble.net/~campbell/emacs/paredit/")
-      (synopsis "Emacs minor mode for editing parentheses")
-      (description
-       "ParEdit (paredit.el) is a minor mode for performing structured editing
+  (package
+    (name "emacs-paredit")
+    (version "25")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://mumble.net/~campbell/git/paredit.git")
+                    (commit (string-append "v" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "1gc6lnk5xqxzl9s2m99hfi07wp4zfhh1k64c1bdrjfalv55nl998"))))
+    (build-system emacs-build-system)
+    (home-page "http://mumble.net/~campbell/emacs/paredit/")
+    (synopsis "Emacs minor mode for editing parentheses")
+    (description
+     "ParEdit (paredit.el) is a minor mode for performing structured editing
 of S-expression data.  The typical example of this would be Lisp or Scheme
 source code.
 
-ParEdit helps **keep parentheses balanced** and adds many keys for moving
+ParEdit helps keep parentheses balanced and adds many keys for moving
 S-expressions and moving around in S-expressions.  Its behavior can be jarring
 for those who may want transient periods of unbalanced parentheses, such as
 when typing parentheses directly or commenting out code line by line.")
-      (license license:gpl3+))))
+    (license license:gpl3+)))
 
 (define-public emacs-puni
   ;; No tagged release upstream
@@ -2841,6 +2904,34 @@ like.  It can be linked with various Emacs mail clients (Message and Mail
 mode, Rmail, Gnus, MH-E, and VM).  BBDB is fully customizable.")
     (license license:gpl3+)))
 
+(define-public emacs-bbdb-vcard
+  ;; No release since Dec 1, 2013.
+  (let ((version "0.4.1") ;3d79fdb4200a64a043e203a3baac95c936095b52, not tagged
+        (revision "88")
+        (commit "113c66115ce68316e209f51ebce56de8dded3606"))
+    (package
+      (name "emacs-bbdb-vcard")
+      (version (git-version version revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://github.com/tohojo/bbdb-vcard")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "1sr5kd2gvw1b4hl147yb60cgx6j730vdnpyr09p7vmpw65hzwlwm"))))
+      (build-system emacs-build-system)
+      (propagated-inputs (list emacs-bbdb))
+      (home-page "https://github.com/tohojo/bbdb-vcard")
+      (synopsis
+       "vCard Import and Export for The Insidious Big Brother Database (BBDB)")
+      (description
+       "@code{bbdb-vcard.el} imports and exports vCards (version 3.0) as
+defined in RFC 2425 and RFC 2426 to/from The Insidious Big Brother Database
+(BBDB).  Version 2.1 vCards are converted into version 3.0 on import.")
+      (license license:gpl2+))))
+
 (define-public emacs-beacon
   (package
     (name "emacs-beacon")
@@ -3439,7 +3530,7 @@ of bibliographic references.")
 (define-public emacs-corfu
   (package
     (name "emacs-corfu")
-    (version "0.28")
+    (version "0.33")
     (source
      (origin
        (method git-fetch)
@@ -3448,7 +3539,7 @@ of bibliographic references.")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "0lmjmaijanhhimkd006y5g1pvpllqgm30wj2y3wf3h4sl7h23rcz"))))
+        (base32 "0c353k6f4i96gajfw1zvidhlwr2brnhhdr39503hpa5wnp69wak7"))))
     (build-system emacs-build-system)
     (arguments
      `(#:phases
@@ -3496,7 +3587,7 @@ be regarded as @code{emacs-company-quickhelp} for @code{emacs-corfu}.")
 (define-public emacs-cape
   (package
     (name "emacs-cape")
-    (version "0.10")
+    (version "0.11")
     (source
      (origin
        (method git-fetch)
@@ -3505,7 +3596,7 @@ be regarded as @code{emacs-company-quickhelp} for @code{emacs-corfu}.")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "0kcnyzksj8yglk67g1130wxzscgipm7cz2hs8mvdqpcbz4i38jny"))))
+        (base32 "0z6ixw7gsx1g7x2xpj5ilslrjrlp6x2ynzh731hs3yf3n281715b"))))
     (build-system emacs-build-system)
     (home-page "https://github.com/minad/cape")
     (synopsis "Completion at point extensions for Emacs")
@@ -4626,7 +4717,6 @@ which is restored where possible when the file is loaded again.")
     (build-system emacs-build-system)
     (arguments
      `(#:tests? #t
-       #:emacs ,emacs                   ; FIXME: tests fail with emacs-minimal
        #:test-command '("./run-tests.sh")))
     (home-page "https://github.com/magnars/s.el")
     (synopsis "Emacs string manipulation library")
@@ -6105,10 +6195,10 @@ blocks with @code{org-babel} in @code{org-mode}.")
       (license license:gpl3+))))
 
 (define-public emacs-ob-restclient
-  (let ((commit "f7449b2068498fe9d8ab9589e0a638148861533f"))
+  (let ((commit "1b021ce1c67c97fa1aa4d2c0816edb7add129e48"))
     (package
       (name "emacs-ob-restclient")
-      (version (git-version "0.02" "2" commit))
+      (version (git-version "0.02" "3" commit))
       (source
        (origin
          (method git-fetch)
@@ -6117,7 +6207,7 @@ blocks with @code{org-babel} in @code{org-mode}.")
                (commit commit)))
          (file-name (git-file-name name version))
          (sha256
-          (base32 "0s3931w9ab3yfml2pmq71rw21yf6hpg7m3vihxyy3vs6zli1cvmq"))))
+          (base32 "1bcjj01q5n9w2cch6brbz8pzwnwsmdlgaa4sf5s97b9frmqb2ffg"))))
       (propagated-inputs
        (list emacs-restclient))
       (build-system emacs-build-system)
@@ -6930,7 +7020,7 @@ files which are intended to be packages.")
       (source (origin
                 (method git-fetch)
                 (uri (git-reference
-                      (url "https://git.sr.ht/~manuel-uberti/flycheck-proselint")
+                      (url "https://git.sr.ht/~manuel-uberti/flymake-proselint")
                       (commit commit)))
                 (file-name (git-file-name name version))
                 (sha256
@@ -6947,11 +7037,9 @@ files which are intended to be packages.")
                   (("\"proselint\"")
                    (string-append
                     "\"" (search-input-file inputs "/bin/proselint") "\""))))))))
-      (propagated-inputs
-       (list emacs-flycheck))
       (inputs
        (list python-proselint))
-      (home-page "https://git.sr.ht/~manuel-uberti/flycheck-proselint")
+      (home-page "https://git.sr.ht/~manuel-uberti/flymake-proselint")
       (synopsis "Flymake backend for @code{proselint}")
       (description "This package adds support for @code{proselint} in Flymake.")
       (license license:gpl3+))))
@@ -11763,26 +11851,40 @@ like @code{org-edit-src-code} but for arbitrary regions.")
 (define-public emacs-projectile
   (package
     (name "emacs-projectile")
-    (version "2.6.0")
-    (source (origin
-              (method url-fetch)
-              (uri (string-append "https://raw.githubusercontent.com/bbatsov"
-                                  "/projectile/v" version "/projectile.el"))
-              (file-name (string-append "projectile-" version ".el"))
-              (sha256
-               (base32
-                "12crymgri4sg7fvnh692f96cm0krmmcnz6x3ypxgq8da84rl34p4"))))
+    (version "2.7.0")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/bbatsov/projectile")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32
+         "0ybd41iss8vd56qv6czpxqq7a99s4h7i3a2r4khy4rf5blj5zdqi"))))
     (build-system emacs-build-system)
+    (arguments
+     (list
+      #:tests? #t
+      #:test-command #~(list "buttercup" "-L" ".")
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'check 'fix-failing-test
+            (lambda _
+              (substitute* "test/projectile-test.el"
+                (("user-emacs-directory") "\".\"")))))))
+    (native-inputs
+     (list emacs-buttercup))
     (propagated-inputs
      (list emacs-dash emacs-pkg-info))
     (home-page "https://github.com/bbatsov/projectile")
     (synopsis "Manage and navigate projects in Emacs easily")
     (description
      "This library provides easy project management and navigation.  The
-concept of a project is pretty basic - just a folder containing special file.
-Currently git, mercurial and bazaar repos are considered projects by default.
-If you want to mark a folder manually as a project just create an empty
-.projectile file in it.")
+concept of a project is pretty basic: just a folder containing special file.
+Currently Git, Mercurial and Bazaar repositories are considered projects by
+default.  If you want to mark a folder manually as a project just create an
+empty @file{.projectile} file in it.")
     (license license:gpl3+)))
 
 (define-public emacs-skeletor
@@ -13325,6 +13427,30 @@ Lua programming language}.")
 news items, openrc and runscripts.")
     (license license:gpl2+)))
 
+(define-public emacs-ebuku
+  ;; Upstream has no tagged release.
+  (let ((revision "1")
+        (commit "0c6cf404a49bd68800221446df186fffa0139325"))
+    (package
+      (name "emacs-ebuku")
+      (version (git-version "0" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://github.com/flexibeast/ebuku")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "09fkzmcvzdbdjaa167wiybj0kir7y12pcq2varjywshvq2l7niz4"))))
+      (build-system emacs-build-system)
+      (home-page "https://github.com/flexibeast/ebuku")
+      (synopsis "Emacs interface to the buku Web bookmark manager")
+      (description
+       "Ebuku provides a basic interface to the @code{buku} Web bookmark
+manager.")
+      (license license:gpl3+))))
+
 (define-public emacs-evil
   ;; Commit message claims this is 1.15.0, but there's no tag for it, so we
   ;; use full git-version instead
@@ -16623,6 +16749,26 @@ for the current file, using the major mode as a hint.  It prompts you to enter
 one if it fails.")
     (license license:gpl3+)))
 
+(define-public emacs-jarchive
+  (package
+    (name "emacs-jarchive")
+    (version "0.8.0")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://git.sr.ht/~dannyfreeman/jarchive")
+                    (commit version)))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "1fi3y5kmy7ginyqg12q797bma638xmam7lrk74x6yhx84xgzb4fq"))))
+    (build-system emacs-build-system)
+    (home-page "https://sr.ht/~dannyfreeman/jarchive")
+    (synopsis "Jarchive teaches Emacs how to navigate to files inside JARs")
+    (description "Jarchive makes Emacs handle Java and LSP URIs pointing to
+ source inside JARs.")
+    (license license:gpl3+)))
+
 (define-public emacs-eldoc
   (package
     (name "emacs-eldoc")
@@ -16929,9 +17075,9 @@ formatting, and utility methods for jsonnet files.")
     (license license:gpl3+)))
 
 (define-public emacs-restclient
-  (let ((commit "ac8aad6c6b9e9d918062fa3c89c22c2f4ec48bc3")
+  (let ((commit "1fb570643b08ba66eb70831b6f874f52546917f1")
         (version "0")
-        (revision "3"))               ;Guix package revision,
+        (revision "4"))               ;Guix package revision,
                                         ;upstream doesn't have official releases
     (package
       (name "emacs-restclient")
@@ -16943,7 +17089,7 @@ formatting, and utility methods for jsonnet files.")
                       (commit commit)))
                 (sha256
                  (base32
-                  "1a2c7xzy7rsan1zcdskia6m7n6j29xacfkqjlfdhzk6rr1bpzkwk"))
+                  "0npij1p1yw4p1f1yrx6bl8q18nav5p2xvbp7qhzhn7lb2fdn5jqv"))
                 (file-name (git-file-name name version))))
       (build-system emacs-build-system)
       (propagated-inputs
@@ -17103,6 +17249,42 @@ additions:
 or @code{treemacs}, but leveraging @code{Dired} to do the job of display.")
     (license license:gpl3+)))
 
+(define-public emacs-dirvish
+  (package
+    (name "emacs-dirvish")
+    (version "2.0.53")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/alexluigit/dirvish")
+                    (commit "c535e2147171be5506f4ff34e862bacbfb3de768")))
+              (sha256
+               (base32
+                "1nmp5ci4dvcpih6phfhk66s98lf8b49qd35ymy29kqkf5v4cnwga"))
+              (file-name (git-file-name name version))))
+    (build-system emacs-build-system)
+    (propagated-inputs (list emacs-transient))
+    (arguments
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          ;; Move the extensions source files to the top level, which
+          ;; is included in the EMACSLOADPATH.
+          (add-after 'unpack 'move-source-files
+            (lambda _
+              (let ((el-files (find-files "./extensions" ".*\\.el$")))
+                (for-each (lambda (f)
+                            (rename-file f (basename f)))
+                          el-files)))))))
+    (home-page "https://github.com/alexluigit/dirvish")
+    (synopsis "Improved version of the Emacs package Dired")
+    (description
+     "Dirvish is an improved version of the Emacs inbuilt package Dired.  It
+not only gives Dired an appealing and highly customizable user interface, but
+also comes together with almost all possible parts required for full usability
+as a modern file manager.")
+    (license license:gpl3+)))
+
 (define-public emacs-which-key
   (package
     (name "emacs-which-key")
@@ -19300,7 +19482,7 @@ match and total match information in the mode-line in various search modes.")
 (define-public emacs-pg
   (package
     (name "emacs-pg")
-    (version "0.16")
+    (version "0.19")
     (source (origin
               (method git-fetch)
               (uri (git-reference (url "https://github.com/emarsden/pg-el")
@@ -19308,7 +19490,7 @@ match and total match information in the mode-line in various search modes.")
               (file-name (git-file-name name version))
               (sha256
                (base32
-                "1jdnslpgdm16klaga02p33g7c8bjzg164kxz3jd7gs5v9gqa6ppz"))))
+                "13fkkpimhxh91hmsp551wzrdcic5ws7wj7vjwnh8l83hsrxmxz0y"))))
     (build-system emacs-build-system)
     (home-page "https://github.com/emarsden/pg-el")
     (synopsis "Emacs Lisp interface for PostgreSQL")
@@ -19904,7 +20086,7 @@ according to a parsing expression grammar.")
 (define-public emacs-eldev
   (package
     (name "emacs-eldev")
-    (version "1.2.2")
+    (version "1.3")
     (source
      (origin
        (method git-fetch)
@@ -19913,7 +20095,7 @@ according to a parsing expression grammar.")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "0d6wbfim0q81sm5m45fjc6n0v6nk32qrgas5nzrs0vslym4bfxna"))))
+        (base32 "112jv9rz6brglffwsablnhafhhnfnq89k9vh8xzbbi6i4xz2l1ak"))))
     (build-system emacs-build-system)
     (arguments
      (list
@@ -20755,8 +20937,8 @@ never confused by comments or @code{foo-bar} matching @code{foo}.")
 (define-public emacs-crdt
   ;; XXX: Upstream does not always tag new releases.  The commit below
   ;; corresponds exactly to latest version bump.
-  (let ((commit "92a7c93a3b4cb4b40f133acd22c89a5fda5cdd30")
-        (version "0.3.4"))
+  (let ((commit "e6d42f42c5dedb73560048f4bf6263c63ffa21bb")
+        (version "0.3.5"))
     (package
       (name "emacs-crdt")
       (version version)
@@ -20768,7 +20950,7 @@ never confused by comments or @code{foo-bar} matching @code{foo}.")
                (commit commit)))
          (file-name (git-file-name name version))
          (sha256
-          (base32 "1vh4d15g62crm4vimc7lgr11ws68g25ylipnvqlrrkvl6qrz3fhj"))))
+          (base32 "16dpg0d8p4fqjl2nir290iim9bb7f87rwnxs16lx67dasvbfawph"))))
       (build-system emacs-build-system)
       (home-page "https://code.librehq.com/qhong/crdt.el")
       (synopsis "Real-time collaborative editing environment")
@@ -20985,22 +21167,22 @@ or expressions with SVG rounded box labels that are fully customizable.")
 (define-public emacs-kind-icon
   (package
     (name "emacs-kind-icon")
-    (version "0.1.7")
+    (version "0.1.9")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "https://elpa.gnu.org/packages/kind-icon-"
                            version ".tar"))
        (sha256
-        (base32 "02imi2qj329yrqvs23d4z7fv8bbaz0fvya6zdswb38blpdri4cn1"))))
+        (base32 "0phssrcpmcidzlwy1577f3f02qwjs6hpavb416302y0n8kkhwvli"))))
     (build-system emacs-build-system)
     (propagated-inputs (list emacs-svg-lib))
     (home-page "https://github.com/jdtsmith/kind-icon")
     (synopsis "Completion kind icons in Emacs")
-    (description "Kind-icon mode adds a colorful icon or text prefix based
-on :company-kind for compatible completion UIs.  The \"kind\" prefix is
-typically used for differentiating completion candidates such as variables,
-functions, etc.")
+    (description "Kind-icon mode adds a colorful icon or text prefix based on
+@code{:company-kind} for compatible completion UIs.  The ``kind'' prefix is
+typically used for differentiating completion candidates such as variables or
+functions.")
     (license license:gpl3+)))
 
 (define-public emacs-svg-icon
@@ -22553,6 +22735,29 @@ It replaces the standard completions buffer with Ido prompt.")
 using user-provided rules.")
     (license license:gpl3+)))
 
+(define-public emacs-on
+  (let ((commit "83baed07a105c135190d49d7ec77f95e8f38fa54")
+        (revision "0"))
+    (package
+      (name "emacs-on")
+      (version (git-version "0.1.0" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://github.com/ajgrf/on.el")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "14ly3w89hf4jgd8wacirxgd8vrgj7vc0hpfn911w5wa4k2a6nzpp"))))
+      (build-system emacs-build-system)
+      (home-page "https://github.com/ajgrf/on.el")
+      (synopsis "Hooks for faster Emacs startup")
+      (description
+       "This package exposes a number of utility hooks and functions ported
+from Doom Emacs.")
+      (license license:expat))))
+
 (define-public emacs-on-screen
   (package
     (name "emacs-on-screen")
@@ -26087,7 +26292,7 @@ according to their use.")
 (define-public emacs-detached
   (package
     (name "emacs-detached")
-    (version "0.9.2")
+    (version "0.10.1")
     (source (origin
               (method git-fetch)
               (uri (git-reference
@@ -26096,7 +26301,7 @@ according to their use.")
               (file-name (git-file-name name version))
               (sha256
                (base32
-                "0bcrqqim6is75d4zadswxp162m9gd34xmb2wxsx9rhvkwq0ln35k"))))
+                "0dvvyqc0nw9has54vps10f5iv831cb29vqvbvx0m2djv9pacqp17"))))
     (arguments
      (list
       #:tests? #t
@@ -28571,8 +28776,7 @@ between \"frame-width\" and \"frame-height\", between \"public\",
        (method url-fetch)
        (uri (string-append
              "https://elpa.gnu.org/packages/ediprolog-"
-             version
-             ".el"))
+             version ".tar"))
        (sha256
         (base32 "021jm5zdxrjg7xcja18vgc2v52rk17xi1k7xxw8q802nmixhy0js"))))
     (build-system emacs-build-system)
@@ -31908,6 +32112,31 @@ ASCII UML sequence diagrams in Emacs, which can be embedded in source code,
 comments or emails.")
       (license license:gpl3+))))
 
+(define-public emacs-ukrainian-holidays
+  ;; There is no proper release.
+  ;; The base version is extracted from the source code.
+  (let ((revision "0")
+        (commit  "e52b0c92843e9f4d0415a7ba3b8559785497d23d"))
+    (package
+      (name "emacs-ukrainian-holidays")
+      (version (git-version "1.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri
+          (git-reference
+           (url "https://github.com/abo-abo/ukrainian-holidays")
+           (commit commit)))
+         (file-name (git-file-name name version))
+         (sha256
+          (base32 "033v4ck979lhkpwblci5clacfc1xnkq03p5d1m566wff8dp5flwz"))))
+      (build-system emacs-build-system)
+      (home-page "https://github.com/abo-abo/ukrainian-holidays")
+      (synopsis "Ukrainian holidays for Emacs calendar")
+      (description
+       "This package provides Ukrainian holidays for Emacs calendar.")
+      (license license:gpl3+))))
+
 (define-public emacs-trashed
   (package
     (name "emacs-trashed")
@@ -32687,14 +32916,14 @@ work on alists, hash-table and arrays.  All functions are prefixed with
 (define-public emacs-xref
   (package
     (name "emacs-xref")
-    (version "1.5.1")
+    (version "1.6.0")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "https://elpa.gnu.org/packages/xref-"
                            version ".tar"))
        (sha256
-        (base32 "131jxsc1sl8q3r9drhylwyfig9qjjkj3hilv3npidp868pr7xdna"))))
+        (base32 "0vqs2l4gypdx475yi0yic0mnsg1f9nm698gi90kh7xfcpmkfcgb4"))))
     (build-system emacs-build-system)
     (home-page "http://elpa.gnu.org/packages/xref.html")
     (synopsis "Cross-referencing commands")
@@ -32874,7 +33103,7 @@ and preferred services can easily be configured.")
 (define-public emacs-vertico
   (package
     (name "emacs-vertico")
-    (version "0.28")
+    (version "0.29")
     (source
      (origin
        (method git-fetch)
@@ -32883,7 +33112,7 @@ and preferred services can easily be configured.")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "0yybwj32k74c5c4rzlpmkq540b8ax0ihn5v7krnri83wn50hr272"))))
+        (base32 "0gqfq7yni470yys9blarmsinjgf1025azlr09g1842w20hwrs7hc"))))
     (build-system emacs-build-system)
     (arguments
      `(#:phases
@@ -33378,7 +33607,7 @@ Fennel code within Emacs.")
 (define-public emacs-org-modern
   (package
    (name "emacs-org-modern")
-   (version "0.5")
+   (version "0.6")
    (source
      (origin
        (method git-fetch)
@@ -33386,7 +33615,7 @@ Fennel code within Emacs.")
              (url "https://github.com/minad/org-modern")
              (commit version)))
        (sha256
-        (base32 "1gny2p3w6ck5sarv6vap2y1lj6h9qaxbh7r7bzszb9qj8rhapk6q"))
+        (base32 "03zpwb475rpbhq1s6101clj0j9mcxdg033clvvybp0p7hm4inwaz"))
        (file-name (git-file-name name version))))
    (build-system emacs-build-system)
    (home-page "https://github.com/minad/org-modern")
@@ -33435,8 +33664,8 @@ headlines, keywords, tables and source blocks.")
       (license license:gpl3+)))) ; License is in pyimport.el
 
 (define-public emacs-straight-el
-  (let ((commit "fed215348076ba9182f634e0770a175220474b5a")
-        (revision "0"))
+  (let ((commit "f21103d97d180fba0b6e2e86ebb0b6269219ef2c")
+        (revision "1"))
     (package
       (name "emacs-straight-el")
       (version (git-version "0" revision commit))
@@ -33449,7 +33678,7 @@ headlines, keywords, tables and source blocks.")
            (commit commit)))
          (file-name (git-file-name name version))
          (sha256
-          (base32 "0z0j670s18mp1bhrsnng0mybcbnlywarhlz7zmrf9399rr513z1x"))))
+          (base32 "1dqhb7kx4hr3cm4gj6qdk9aav05vc016y4nks2dj1sy88wia6wsv"))))
       (build-system emacs-build-system)
       (arguments
        (list
@@ -33586,7 +33815,7 @@ with popups, which also work in the terminal.")
 (define-public emacs-popon
   (package
     (name "emacs-popon")
-    (version "0.11")
+    (version "0.12")
     (source
      (origin
        (method git-fetch)
@@ -33596,7 +33825,7 @@ with popups, which also work in the terminal.")
          (commit (string-append "v" version))))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "14hf1n9d7rqfzr58kjsvjq63v3iamk3szvcn6zms7ry8x70v3lmv"))))
+        (base32 "0wkydg326ql8cvvmibq1nf6y40d1b0ax0p892pwncmi7awnf20gr"))))
     (build-system emacs-build-system)
     (home-page "https://codeberg.org/akib/emacs-popon/")
     (synopsis "Pop floating text on a window")
@@ -33792,16 +34021,16 @@ into the current buffer.")
         (revision "0"))
     (package
       (name "emacs-flymake-mypy")
-      (version (git-version "0.2.0" revision commit))
+      (version "0.3.0")
       (source (origin
                 (method git-fetch)
                 (uri (git-reference
                       (url "https://github.com/com4/flymake-mypy")
-                      (commit commit)))
+                      (commit version)))
                 (file-name (git-file-name name version))
                 (sha256
                  (base32
-                  "124pfa1kwrapwylbrvkzg3jwcmlsvfklg33ms9ki32khvglmff5h"))))
+                  "1zaa2kljsmm13layqmb7dwd7l2x3a5ymzzmzjjhykc67kbyjvvkk"))))
       (build-system emacs-build-system)
       (home-page "https://github.com/com4/flymake-mypy")
       (synopsis "Flymake checker for mypy")
@@ -33845,6 +34074,187 @@ using mypy.")
 process via its IPC interface.")
       (license license:gpl3+))))
 
+(define-public emacs-apel-lb
+  ;; No release since Jun 15, 2010.
+  (let ((version "10.8")                ;tag chise-base-0_25
+        (revision "81")
+        (commit "82eb2325bd149dc57b43a9ce9402c6c6183e4052"))
+    (package
+      (name "emacs-apel-lb")
+      (version (git-version version revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://github.com/wanderlust/apel")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "0qiw19pn1cs8y571irw7bjdygkvwan9ch2i1dg139dri4b6q1il6"))))
+      (build-system emacs-build-system)
+      (home-page "https://www.emacswiki.org/emacs/WanderLust")
+      (synopsis "Library for making portable Emacs Lisp programs")
+      (description
+       "A Portable Emacs Library (APEL) is a library for making portable Emacs
+Lisp programs.  APEL-LB is a variant of APEL, which features supports to
+latest Emacs.")
+      (license license:gpl2+))))
+
+(define-public emacs-flim-lb
+  ;; No release since Nov 28, 2007.
+  (let ((version "1.14.9")
+        (revision "133")
+        (commit "57c6b868aa314717f40a520daed7249665e8d992"))
+    (package
+      (name "emacs-flim-lb")
+      (version (git-version version revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://github.com/wanderlust/flim")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "1mf8r5mf3bd0719fnhifb6lfvl7n4m552crcdhkbkkif8srrl6df"))))
+      (build-system emacs-build-system)
+      (propagated-inputs (list emacs-apel-lb emacs-oauth2))
+      (home-page "https://www.emacswiki.org/emacs/WanderLust")
+      (synopsis
+       "Library for basic features about message representation or encoding")
+      (description
+       "FLIM is a library to provide basic features about message representation
+or encoding.  FLIM-LB is a variant of FLIM, which features supports to latest
+Emacs.")
+      (license license:gpl2+))))
+
+(define-public emacs-semi-epg
+  ;; No release since Dec 24, 2003.
+  (let ((version "1.14.6")
+        (revision "241")
+        (commit "ac3e726ca94ed245c25881ec8d7177d0d834ea6a"))
+    (package
+      (name "emacs-semi-epg")
+      (version (git-version version revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://github.com/wanderlust/semi")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "1bg07y6svvg1mmlr455x3j1anjp3wbv27s6b2inp294rbwprm41n"))))
+      (build-system emacs-build-system)
+      (propagated-inputs (list emacs-bbdb-vcard emacs-flim-lb))
+      (home-page "https://www.emacswiki.org/emacs/WanderLust")
+      (synopsis "Library to provide MIME feature for GNU Emacs")
+      (description
+       "SEMI is a package for GNU Emacs to provide features related with MIME
+user interface.  SEMI-EPG is a variant of SEMI, which features supports to
+EasyPG and latest Emacs.")
+      (license license:gpl2+))))
+
+(define-public emacs-wanderlust
+  ;; No release since Jan 15, 2010.
+  ;; FIXME: Building with emacs-next-pgtk would yield a void variable related
+  ;; macro-expansion failure at runtime, so don't rewrite emacs input of this
+  ;; package.
+  (let ((version "2.15.9")
+        (revision "779")
+        (commit "f5cb2f0cf5e2c893acf2e669fd549836828dfdfc"))
+    (package
+      (name "emacs-wanderlust")
+      (version (git-version version revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://github.com/wanderlust/wanderlust")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (modules '((guix build utils)))
+                (snippet
+                 '(begin (substitute* "WL-CFG"
+                           ((".*WL_PREFIX.*")
+                            (string-append "(setq wl-install-utils t)" "\n"
+                                           "(setq WL_PREFIX \"\")" "\n"
+                                           "(setq ELMO_PREFIX \"\")" "\n")))
+                         (substitute* "Makefile"
+                           (("package-user-dir") "NONE"))))
+                (sha256
+                 (base32
+                  "1ijs57wv1vrh33vn311hgkp42vlmjyi998nc4qdrqi7yy9j8hl1h"))))
+      (build-system emacs-build-system)
+      (arguments
+       (list #:phases
+             #~(modify-phases %standard-phases
+                 (add-after 'expand-load-path 'chdir-elmo
+                   (lambda _
+                     (chdir "elmo")))
+                 (add-after 'chdir-elmo 'expand-load-path-elmo
+                   (assoc-ref %standard-phases 'expand-load-path))
+                 (add-after 'expand-load-path-elmo 'chdir-utils
+                   (lambda _
+                     (chdir "../utils")))
+                 (add-after 'chdir-utils 'expand-load-path-utils
+                   (assoc-ref %standard-phases 'expand-load-path))
+                 (add-after 'expand-load-path-utils 'chdir-wl
+                   (lambda _
+                     (chdir "../wl")))
+                 (add-after 'chdir-wl 'expand-load-path-wl
+                   (assoc-ref %standard-phases 'expand-load-path))
+                 (add-after 'expand-load-path-wl 'change-directory
+                   (lambda _
+                     (chdir "..")))
+                 (add-after 'install 'install-via-makefile
+                   (lambda* (#:key inputs #:allow-other-keys)
+                     (let ((emacs (search-input-file inputs "/bin/emacs"))
+                           (lispdir (elpa-directory #$output))
+                           (infodir (string-append #$output "/share/info")))
+                       (for-each mkdir-p (list lispdir infodir))
+                       (substitute* "Makefile"
+                         (("(EMACS\t= )emacs" all m)
+                          (string-append m emacs))
+                         (("(LISPDIR = )NONE" all m)
+                          (string-append m lispdir))
+                         (("(PIXMAPDIR = )NONE" all m)
+                          (string-append m lispdir "/icons"))
+                         (("(INFODIR = )NONE" all m)
+                          (string-append m infodir))))
+                     (invoke "make" "install")
+                     (invoke "make" "install-info"))))))
+      (propagated-inputs (list emacs-semi-epg))
+      (home-page "https://www.emacswiki.org/emacs/WanderLust")
+      (synopsis "Yet Another Message Interface on Emacsen")
+      (description
+       "Wanderlust is an mail/news management system on Emacsen.  It supports
+IMAP4rev1(RFC2060), NNTP, POP and local message files.
+
+The main features of Wanderlust:
+
+@itemize
+@item Pure elisp implementation.
+@item Supports IMAP4rev1, NNTP, POP(POP3/APOP), MH and Maildir format.
+@item Unified access method to messages based on Mew-like Folder Specification.
+@item Mew-like Key-bind and mark handling.
+@item Manages unread messages.
+@item Interactive thread display.
+@item Folder Mode shows the list of subscribed folders.
+@item Message Cache, Disconnected Operation.
+@item MH-like FCC (Fcc: %Backup and Fcc: $Backup is allowed).
+@item MIME compliant (by SEMI).
+@item Transmission of news and mail are unified by Message transmitting draft.
+@item Graphical list of folders.
+@item View a part of message without retrieving the whole message (IMAP4).
+@item Server-side message look up (IMAP4), multi-byte characters are allowed.
+@item Virtual Folders.
+@item Supports compressed folder using common archiving utilities.
+@item Old articles in folders are automatically removed/archived (Expiration).
+@item Automatic re-file.
+@item Template function makes it convenient to send fixed form messages.
+@end itemize\n")
+      (license license:gpl2+))))
+
 (define-public emacs-waveform
   ;; XXX: Upstream provides no Version keyword.  Using 0 as base version.
   (let ((commit "ee52c6a72b3e9890743e3a6e2fc1f3195f5687b2")
diff --git a/gnu/packages/engineering.scm b/gnu/packages/engineering.scm
index 21569b07c9..43e23e30a8 100644
--- a/gnu/packages/engineering.scm
+++ b/gnu/packages/engineering.scm
@@ -3310,7 +3310,7 @@ visualization, matrix manipulation.")
 (define-public prusa-slicer
   (package
     (name "prusa-slicer")
-    (version "2.4.2")
+    (version "2.5.0")
     (source
      (origin
        (method git-fetch)
@@ -3319,7 +3319,7 @@ visualization, matrix manipulation.")
          (url "https://github.com/prusa3d/PrusaSlicer")
          (commit (string-append "version_" version))))
        (file-name (git-file-name name version))
-       (sha256 (base32 "17p56f0zmiryy8k4da02in1l6yxniz286gf9yz8s1gaz5ksqj4af"))
+       (sha256 (base32 "17ic92ww2ny0frxyv7ajwdwa0fq70ygq562ik8sh94jx67jvxdy0"))
        (modules '((guix build utils)))
        (snippet
         '(begin
@@ -3368,10 +3368,12 @@ visualization, matrix manipulation.")
            hidapi
            ilmbase
            libigl
+           libjpeg-turbo
            libpng
            mesa
            mpfr
            nlopt
+           opencascade-occt
            openvdb
            pango
            tbb
diff --git a/gnu/packages/finance.scm b/gnu/packages/finance.scm
index c8f3ee9d1d..feb533eca7 100644
--- a/gnu/packages/finance.scm
+++ b/gnu/packages/finance.scm
@@ -129,10 +129,10 @@
   #:use-module (gnu packages xml)
   #:use-module (gnu packages gnuzilla))
 
-(define-public bitcoin-core-0.21
+(define-public bitcoin-core-23.0
   (package
     (name "bitcoin-core")
-    (version "0.21.2")
+    (version "23.0")
     (source (origin
               (method url-fetch)
               (uri
@@ -140,7 +140,7 @@
                               version "/bitcoin-" version ".tar.gz"))
               (sha256
                (base32
-                "17nvir1yc6mf4wr1fn4xsabw49cd5p9vig8wj77vv4anzi8zfij1"))))
+                "01fcb90pqip3v77kljykx51cmg7jdg2cmp7ys0a40svdkps8nx16"))))
     (build-system gnu-build-system)
     (native-inputs
      (list autoconf
@@ -207,23 +207,10 @@ of the bitcoin protocol.  This package provides the Bitcoin Core command
 line client and a client based on Qt.")
     (license license:expat)))
 
-(define-public bitcoin-core-0.20
-  (package
-    (inherit bitcoin-core-0.21)
-    (version "0.20.2")
-    (source (origin
-              (method url-fetch)
-              (uri
-               (string-append "https://bitcoincore.org/bin/bitcoin-core-"
-                              version "/bitcoin-" version ".tar.gz"))
-              (sha256
-               (base32
-                "14smp5vmh7baabl856wlg7w7y5910jhx6c02mlkm4hkywf3yylky"))))))
-
 ;; The support lifetimes for bitcoin-core versions can be found in
 ;; <https://bitcoincore.org/en/lifecycle/#schedule>.
 
-(define-public bitcoin-core bitcoin-core-0.21)
+(define-public bitcoin-core bitcoin-core-23.0)
 
 (define-public hledger
   (package
@@ -553,7 +540,7 @@ do so.")
 (define-public electrum
   (package
     (name "electrum")
-    (version "4.2.1")
+    (version "4.3.2")
     (source
      (origin
        (method url-fetch)
@@ -561,7 +548,7 @@ do so.")
                            version "/Electrum-"
                            version ".tar.gz"))
        (sha256
-        (base32 "0w41411zq07kx0351wxkmpn0wr42wd2nx0m6v0iwvpsggx654b6r"))
+        (base32 "1kbyinm9fnxpx9chkyd11yr9rxvcxvw3ml7kzvxcfa8v7jnl0dmx"))
        (modules '((guix build utils)))
        (snippet
         '(begin
@@ -628,7 +615,7 @@ other machines/servers.  Electrum does not download the Bitcoin blockchain.")
 (define-public electron-cash
   (package
     (name "electron-cash")
-    (version "4.2.11")
+    (version "4.2.12")
     (source
      (origin
        (method git-fetch)
@@ -637,7 +624,7 @@ other machines/servers.  Electrum does not download the Bitcoin blockchain.")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "1g0xnb63c52l379zrqkfhxlkg1d2hf2dgjs2swspa0vah845r282"))))
+        (base32 "1bfnfpdyi3q5zq0zj07dq82aj3cihnr7j82gy4ch97182lsl6nms"))))
     (build-system python-build-system)
     (arguments
      (list
@@ -2134,7 +2121,7 @@ and manipulation.")
 (define-public xmrig
   (package
     (name "xmrig")
-    (version "6.18.0")
+    (version "6.18.1")
     (source
      (origin
        (method git-fetch)
@@ -2142,7 +2129,7 @@ and manipulation.")
              (url "https://github.com/xmrig/xmrig")
              (commit (string-append "v" version))))
        (file-name (git-file-name name version))
-       (sha256 (base32 "1ncnfjpjwjdv29plyiam2nh01bfni49sgfi3qkijygi1450w71dx"))
+       (sha256 (base32 "0f0kly374pkgnpnx60hac0bg9297a5zhycss6p37iavayn28jg39"))
        (modules '((guix build utils)))
        (snippet
         ;; TODO: Try to use system libraries instead of bundled ones in
@@ -2190,7 +2177,7 @@ mining.")
 (define-public p2pool
   (package
     (name "p2pool")
-    (version "2.2.1")
+    (version "2.5")
     (source
      (origin
        (method git-fetch)
@@ -2199,7 +2186,7 @@ mining.")
              (commit (string-append "v" version))
              (recursive? #t)))
        (file-name (git-file-name name version))
-       (sha256 (base32 "19pn7axj96yvza2x7678rs79c2vgmhl8d7f9ki72v2n6l2630fw8"))
+       (sha256 (base32 "1kdsxh6f24zp7h7bwkrin2mc81ysfny5wprzgy41h2bc6dpq067w"))
        (modules '((guix build utils)))
        (snippet
         #~(for-each delete-file-recursively
diff --git a/gnu/packages/firmware.scm b/gnu/packages/firmware.scm
index 696814cc71..e9bb3ed450 100644
--- a/gnu/packages/firmware.scm
+++ b/gnu/packages/firmware.scm
@@ -2,7 +2,7 @@
 ;;; Copyright © 2014, 2015, 2016 Ludovic Courtès <ludo@gnu.org>
 ;;; Copyright © 2016 Eric Bavier <bavier@member.fsf.org>
 ;;; Copyright © 2017 David Craven <david@craven.ch>
-;;; Copyright © 2017, 2018 Efraim Flashner <efraim@flashner.co.il>
+;;; Copyright © 2017, 2018, 2022 Efraim Flashner <efraim@flashner.co.il>
 ;;; Copyright © 2018, 2020 Tobias Geerinckx-Rice <me@tobias.gr>
 ;;; Copyright © 2018 Vagrant Cascadian <vagrant@debian.org>
 ;;; Copyright © 2019 Mathieu Othacehe <m.othacehe@gmail.com>
@@ -259,19 +259,11 @@ driver.")
                          help2man
                          gettext-minimal))
     (inputs (list bash-completion
-                  glib
                   libgudev
                   libxmlb
-                  gusb
                   sqlite
-                  libarchive
-                  libjcat
-                  json-glib
-                  curl
                   polkit
                   eudev
-                  gcab
-                  gnutls
                   libelf
                   tpm2-tss
                   cairo
@@ -281,6 +273,15 @@ driver.")
                   mingw-w64-tools
                   libsmbios
                   gnu-efi))
+    ;; In Requires of fwupd*.pc.
+    (propagated-inputs (list curl
+                             gcab
+                             glib
+                             gnutls
+                             gusb
+                             json-glib
+                             libarchive
+                             libjcat))
     (home-page "https://fwupd.org/")
     (synopsis "Daemon to allow session software to update firmware")
     (description "This package aims to make updating firmware on GNU/Linux
@@ -644,7 +645,7 @@ Virtual Machines.  OVMF contains a sample UEFI firmware for QEMU and KVM.")
 (define* (make-arm-trusted-firmware platform #:optional (arch "aarch64"))
   (package
     (name (string-append "arm-trusted-firmware-" platform))
-    (version "2.6")
+    (version "2.8")
     (source
       (origin
         (method git-fetch)
@@ -655,27 +656,27 @@ Virtual Machines.  OVMF contains a sample UEFI firmware for QEMU and KVM.")
         (file-name (git-file-name "arm-trusted-firmware" version))
        (sha256
         (base32
-         "1j0rn33pwgmksqliwf2npm2px84qmbyma9iq8zpllwfc7dsl6gx9"))))
+         "0grq3fgxi9xhcljnhwlxjvdghyz15gaq50raw41xy4lm8rkmnzp3"))
+       (snippet
+        #~(begin
+            (use-modules (guix build utils))
+            ;; Remove binary blobs which do not contain source or proper license.
+            (for-each (lambda (file)
+                        (delete-file file))
+                      (find-files "." "\\.bin$"))))))
     (build-system gnu-build-system)
     (arguments
      `(#:phases
        (modify-phases %standard-phases
          (delete 'configure) ; no configure script
-         ;; Remove binary blobs which do not contain source or proper license.
-         (add-after 'unpack 'remove-binary-blobs
-           (lambda _
-             (for-each (lambda (file)
-                         (delete-file file))
-                       (find-files "." ".*\\.bin$"))))
          (replace 'install
            (lambda* (#:key outputs #:allow-other-keys)
              (let ((out (assoc-ref outputs "out"))
-                   (bin (find-files "." ".*\\.(bin|elf)$")))
+                   (bin (find-files "." "\\.(bin|elf)$")))
                (for-each
                  (lambda (file)
                    (install-file file out))
-                 bin))
-             #t)))
+                 bin)))))
        #:make-flags (list (string-append "PLAT=" ,platform)
                           ,@(if (and (not (string-prefix? "aarch64"
                                                           (%current-system)))
diff --git a/gnu/packages/fonts.scm b/gnu/packages/fonts.scm
index 343f736ed2..95e99d5a73 100644
--- a/gnu/packages/fonts.scm
+++ b/gnu/packages/fonts.scm
@@ -35,7 +35,7 @@
 ;;; Copyright © 2020 Raghav Gururajan <raghavgururajan@disroot.org>
 ;;; Copyright © 2020, 2021 Julien Lepiller <julien@lepiller.eu>
 ;;; Copyright © 2020 Zhu Zihao <all_but_last@163.com>
-;;; Copyright © 2020, 2021 Simen Endsjø <simendsjo@gmail.com>
+;;; Copyright © 2020, 2021, 2022 Simen Endsjø <simendsjo@gmail.com>
 ;;; Copyright © 2020 Tim Van den Langenbergh <tmt_vdl@gmx.com>
 ;;; Copyright © 2020 Nicolò Balzarotti <nicolo@nixo.xyz>
 ;;; Copyright © 2021 Antoine Côté <antoine.cote@posteo.net>
@@ -1498,7 +1498,7 @@ guix repl <<EOF
              (ice-9 string-fun)
              (gnu packages fonts))
 
-(let ((new-version "15.2.0")
+(let ((new-version "16.4.0")
       (iosevka-hashes #nil)
       (iosevka-fails #nil))
   (for-each (lambda (font)
@@ -1532,7 +1532,7 @@ EOF
 (define-public font-iosevka
   (package
     (name "font-iosevka")
-    (version "15.2.0")
+    (version "16.4.0")
     (source
      (origin
        (method url-fetch/zipbomb)
@@ -1540,7 +1540,7 @@ EOF
                            "/releases/download/v" version
                            "/ttc-iosevka-" version ".zip"))
        (sha256
-        (base32 "0yyz8vmpi8pww0p9na564lvbkwhdhpk4bcyrli91dn5gq0pc1pvv"))))
+        (base32 "07v98pr0anqbxn1yc55245k5ixxzfk2wmfq67zhz84aa18viqhbc"))))
     (build-system font-build-system)
     (home-page "https://be5invis.github.io/Iosevka/")
     (synopsis "Coders' typeface, built from code")
@@ -1563,7 +1563,7 @@ programming.  Iosevka is completely generated from its source code.")
                            "/releases/download/v" version
                            "/ttc-iosevka-slab-" version ".zip"))
        (sha256
-        (base32 "1qy86kdl6lgq5k1qb97adibpfjm4vg1wdnxbqizhqka5bc7avyzb"))))))
+        (base32 "063qk1d75l1jq7gdwzqxd7j8j56g7da0aagsqm0lvwl217l7x48b"))))))
 
 (define-public font-iosevka-term
   (package
@@ -1577,7 +1577,7 @@ programming.  Iosevka is completely generated from its source code.")
                            "/releases/download/v" version
                            "/ttf-iosevka-term-" version ".zip"))
        (sha256
-        (base32 "15znvvkhldgbl9k04pwrrnvmjnanw2fr92c0zspg7bbw7id2v510"))))
+        (base32 "17465bvg6fap53xfqwrg2g4fasv01w86wh658n1rf6djs3yzn1gx"))))
     (arguments
      `(#:phases
        (modify-phases %standard-phases
@@ -1598,7 +1598,7 @@ programming.  Iosevka is completely generated from its source code.")
                            "releases/download/v" version "/"
                            "ttf-iosevka-term-slab-" version ".zip"))
        (sha256
-        (base32 "1rla7kcb94c7daklp4av27gix86cmwsrqg6884zmv5zfnhz0r700"))))
+        (base32 "00pc4d8awdiziyzncah3fnh0ppvcdvi9cd7vyknl68f6fj283fvm"))))
     (arguments
      `(#:phases
        (modify-phases %standard-phases
@@ -1619,7 +1619,7 @@ programming.  Iosevka is completely generated from its source code.")
                            "/releases/download/v" version
                            "/ttc-iosevka-aile-" version ".zip"))
        (sha256
-        (base32 "1lciycahvxgvmcniq4h3m1v3rc42nmv8ydb0fpbl9g4sc0qp81hq"))))))
+        (base32 "03y0xijb7c0kampm3gjb69mv8hikhsgqhlw1w3zfcjhr2vc62g6q"))))))
 
 (define-public font-iosevka-curly
   (package
@@ -1633,7 +1633,7 @@ programming.  Iosevka is completely generated from its source code.")
                            "releases/download/v" version  "/"
                            "ttc-iosevka-curly-" version ".zip"))
        (sha256
-        (base32 "02jvrj7kzd4bx3maj1bq2p9j746b8c5713d8lqkxx4fn9fm0zppq"))))))
+        (base32 "1i31zj0j8npgx7wn2qibih48s76qjxakz14sa2hgx908p8xyfwq5"))))))
 
 (define-public font-iosevka-curly-slab
   (package
@@ -1647,7 +1647,7 @@ programming.  Iosevka is completely generated from its source code.")
                            "releases/download/v" version  "/"
                            "ttc-iosevka-curly-slab-" version ".zip"))
        (sha256
-        (base32 "1bhvf95xs74wm8srsvl4yxwvl36llk93mpl1y9acc5z9rdcpzjqq"))))))
+        (base32 "1xijhk5vbgs3c89a7g9cfjqjqv801gimjja4wqpvaficab692jh2"))))))
 
 (define-public font-iosevka-etoile
   (package
@@ -1661,12 +1661,12 @@ programming.  Iosevka is completely generated from its source code.")
                            "/releases/download/v" version
                            "/ttc-iosevka-etoile-" version ".zip"))
        (sha256
-        (base32 "1zmgfxfsbxv1k4fwnc7g2jlfhmlzp5kap8m3f10fqanpnkd0yf08"))))))
+        (base32 "1rqagk6gyja15fa4m107ylbjwbhn811gbl9lbr9yzashw4drjpp9"))))))
 
 (define-public font-sarasa-gothic
   (package
     (name "font-sarasa-gothic")
-    (version "0.36.8")
+    (version "0.37.4")
     (source
      (origin
        (method url-fetch)
@@ -1674,7 +1674,7 @@ programming.  Iosevka is completely generated from its source code.")
                            "/releases/download/v" version
                            "/sarasa-gothic-ttc-" version ".7z"))
        (sha256
-        (base32 "01fn5mzr1rcz0c8nbhabwbv1pq1c3ylf2msxldc9adks1pi45fmh"))))
+        (base32 "12i8lccl4ysinhz40s2fz6249r9n35in4rqmk3a0fgcjfaby3kfm"))))
     (build-system font-build-system)
     (arguments
      `(#:phases (modify-phases %standard-phases
diff --git a/gnu/packages/freedesktop.scm b/gnu/packages/freedesktop.scm
index a972f05d91..40b7de4467 100644
--- a/gnu/packages/freedesktop.scm
+++ b/gnu/packages/freedesktop.scm
@@ -61,6 +61,7 @@
   #:use-module (guix build-system perl)
   #:use-module (guix build-system python)
   #:use-module (guix build-system glib-or-gtk)
+  #:use-module (guix build-system qt)
   #:use-module (gnu packages)
   #:use-module (gnu packages acl)
   #:use-module (gnu packages admin)
@@ -73,11 +74,13 @@
   #:use-module (gnu packages cmake)
   #:use-module (gnu packages compression)
   #:use-module (gnu packages cryptsetup)
+  #:use-module (gnu packages cups)
   #:use-module (gnu packages curl)
   #:use-module (gnu packages databases)
   #:use-module (gnu packages disk)
   #:use-module (gnu packages docbook)
   #:use-module (gnu packages documentation)
+  #:use-module (gnu packages fcitx)
   #:use-module (gnu packages file)
   #:use-module (gnu packages fontutils)
   #:use-module (gnu packages gawk)
@@ -91,9 +94,12 @@
   #:use-module (gnu packages graphviz)
   #:use-module (gnu packages gstreamer)
   #:use-module (gnu packages gtk)
+  #:use-module (gnu packages ibus)
   #:use-module (gnu packages image)
+  #:use-module (gnu packages kde-frameworks)
   #:use-module (gnu packages language)
   #:use-module (gnu packages libffi)
+  #:use-module (gnu packages libreoffice)
   #:use-module (gnu packages libunwind)
   #:use-module (gnu packages libusb)
   #:use-module (gnu packages linux)
@@ -386,6 +392,81 @@ inappropriate content.")
       license:gpl2+
       license:lgpl2.1+))))
 
+(define-public maliit-framework
+  (package
+    (name "maliit-framework")
+    (version "2.3.0")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/maliit/framework")
+                    (commit version)))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "1dkjxvfxg56hfy70j6ibfklfyv57jiha4vgc3ggl60r5kjx65s5b"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules
+                         wayland-protocols
+                         pkg-config
+                         doxygen
+                         graphviz
+                         `(,glib "bin"))) ;for gdbus-codegen))
+    (inputs (list qtbase-5
+                  qtdeclarative-5
+                  qtwayland-5
+                  wayland
+                  libxkbcommon
+                  dbus
+                  eudev
+                  glib))
+    (home-page "https://github.com/maliit/framework")
+    (synopsis "Core libraries of Maliit")
+    (description "This package provides Maliit provides a flexible input
+method framework.")
+    (license license:lgpl2.1+)))
+
+(define-public maliit-keyboard
+  (package
+    (name "maliit-keyboard")
+    (version "2.3.1")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/maliit/keyboard")
+                    (commit version)))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "0g89lckl4wzwamc89hs8871fbiyrsjwzk5b6ic4vhc4d1clyqzaw"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list #:tests? #f
+           #:phases #~(modify-phases %standard-phases
+                        (add-after 'install 'install-schemas
+                          (lambda* (#:key source outputs #:allow-other-keys)
+                            (with-directory-excursion (string-append #$output
+                                                       "/share/glib-2.0/schemas")
+                              (invoke "glib-compile-schemas" ".")))))))
+    (native-inputs (list extra-cmake-modules pkg-config gettext-minimal
+                         `(,glib "bin")))
+    (inputs (list hunspell
+                  glib
+                  libchewing
+                  libpinyin
+                  maliit-framework
+                  presage
+                  qtbase-5
+                  qtdeclarative-5
+                  qtmultimedia-5
+                  qtquickcontrols2-5))
+    (home-page "https://github.com/maliit/keyboard")
+    (synopsis "Maliit Keyboard")
+    (description
+     "This package provides virtual keyboard for Wayland and X11
+display servers.  It supports many different languages and emoji.")
+    (license license:gpl3+)))
+
 (define-public xdg-utils
   (package
     (name "xdg-utils")
@@ -874,32 +955,37 @@ with localed.  This package is extracted from the broader systemd package.")
 (define-public packagekit
   (package
     (name "packagekit")
-    (version "1.1.13")
+    (version "1.2.5")
     (source (origin
-             (method url-fetch)
-             (uri (string-append
-                   "https://www.freedesktop.org/software/"
-                   "PackageKit/releases/"
-                   "PackageKit-" version ".tar.xz"))
-             (sha256
-              (base32
-               "1dr1laic65ld95abp2yxbwvijnngh0dwyb1x49x4wjm5rhq43dl8"))))
-    (build-system gnu-build-system)
+              (method url-fetch)
+              (uri (string-append "https://www.freedesktop.org/software/"
+                                  "PackageKit/releases/" "PackageKit-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "09md23m4fw87x264mls1f5isrswk6iw7y9g4hr1nib008wbbk370"))))
+    (build-system meson-build-system)
     (arguments
-     `(#:tests? #f
-       #:make-flags (list (string-append "BASH_COMPLETIONS_DIR="
-                                         %output "/etc/bash_completion.d"))
-       #:configure-flags
-       '("--disable-systemd")))
+     (list #:tests? #f
+           #:configure-flags #~'("-Dsystemd=false" "-Doffline_update=false")))
     (native-inputs
-     `(("intltool" ,intltool)
-       ("pkg-config" ,pkg-config)
-       ("python" ,python-wrapper)
-       ("glib:bin" ,glib "bin")))
+     (list bash-completion
+           docbook-xsl
+           gettext-minimal
+           `(,glib "bin")
+           gobject-introspection
+           libxml2                      ;for XML_CATALOG_FILES
+           libxslt
+           pkg-config
+           python-wrapper
+           vala))
     (inputs
-     (list glib bash-completion polkit))
-    (propagated-inputs
-     (list sqlite))
+     (list glib
+           gstreamer
+           gst-plugins-base
+           gtk+
+           polkit))
+    (propagated-inputs (list sqlite))
     (home-page "https://www.freedesktop.org/software/PackageKit/")
     (synopsis "API for package management, through D-Bus")
     (description
@@ -1105,6 +1191,29 @@ protocol either in Wayland core, or some other protocol in wayland-protocols.")
                (base32
                 "04vgllmpmrv14x3x64ns01vgwx4hriljayjkz9idgbv83i63hly5"))))))
 
+(define-public wayland-utils
+  (package
+    (name "wayland-utils")
+    (version "1.1.0")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://gitlab.freedesktop.org/wayland/wayland-utils")
+                    (commit version)))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "04k1yhyh7h4xawbhpz9pf6cpfmmp1l862fdgsvvnyp4hg9n3j9aj"))))
+    (build-system meson-build-system)
+    (native-inputs (list pkg-config))
+    (inputs (list libdrm wayland wayland-protocols-next))
+    (home-page "https://wayland.freedesktop.org/")
+    (synopsis "Display information about the Wayland protocols")
+    (description "This package provides @code{wayland-info} tool that can be
+used to check which Wayland protocols and versions are advertised by the Wayland
+compositor.")
+    (license license:expat)))
+
 (define-public waylandpp
   (package
     (name "waylandpp")
@@ -2551,6 +2660,42 @@ which uses GTK+ and various pieces of GNOME infrastructure, such as the
 interfaces.")
     (license license:lgpl2.1+)))
 
+(define-public xdg-desktop-portal-kde
+  (package
+    (name "xdg-desktop-portal-kde")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version "/"
+                                  name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0l3lmwihxyl65y0mkyg3afk1k6gc0ldjw2vg92g7yydbgmn39q7k"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list cups
+                  kcoreaddons
+                  kconfig
+                  ki18n
+                  kdeclarative
+                  kio
+                  kirigami
+                  knotifications
+                  plasma-framework
+                  plasma-wayland-protocols
+                  kwayland
+                  kwidgetsaddons
+                  kwindowsystem
+                  kiconthemes
+                  qtdeclarative-5
+                  qtwayland-5
+                  wayland))
+    (synopsis "Backend implementation for xdg-desktop-portal using Qt/KF5")
+    (description "This package provides a backend implementation
+for xdg-desktop-portal that is using Qt/KF5.")
+    (home-page "https://invent.kde.org/plasma/xdg-desktop-portal-kde")
+    (license license:lgpl2.0+)))
+
 (define-public xdg-desktop-portal-wlr
   (package
     (name "xdg-desktop-portal-wlr")
diff --git a/gnu/packages/games.scm b/gnu/packages/games.scm
index 357dee69d0..d7af172d53 100644
--- a/gnu/packages/games.scm
+++ b/gnu/packages/games.scm
@@ -880,14 +880,14 @@ Quizzes: arithmetic and quiz.")
 (define-public bzflag
   (package
     (name "bzflag")
-    (version "2.4.24")
+    (version "2.4.26")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "https://download.bzflag.org/bzflag/source/"
                            version "/bzflag-" version ".tar.bz2"))
        (sha256
-        (base32 "1i73ijlnxsz52fhqgkj2qcvibfgav3byq1is68gab2zwnyz330az"))))
+        (base32 "050h933lmcdf4bw9z3c6g3k8c9sch9f6kq57jp2ivb96zw2h90q1"))))
     (build-system gnu-build-system)
     (arguments
      (list
@@ -6239,7 +6239,7 @@ emerges from a sewer hole and pulls her below ground.")
 (define-public cdogs-sdl
   (package
     (name "cdogs-sdl")
-    (version "0.8.0")
+    (version "1.4.0")
     (source
      (origin
        (method git-fetch)
@@ -6248,7 +6248,7 @@ emerges from a sewer hole and pulls her below ground.")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "0vx37zb2iw7sfw5a2bs97ydlmb301nvy485ybdm8g46c5hn9s13c"))))
+        (base32 "1505z8rli59i1ych4rzwbf4dvhv72icdj22n1xarb8xfyz0wyp3b"))))
     (build-system cmake-build-system)
     (arguments
      `(#:configure-flags
@@ -10451,14 +10451,14 @@ get high scores.")
 (define-public burgerspace
   (package
     (name "burgerspace")
-    (version "1.9.4")
+    (version "1.9.5")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "http://perso.b2b2c.ca/~sarrazip/dev/"
                            "burgerspace-" version ".tar.gz"))
        (sha256
-        (base32 "1xb4immzmd419aa08lgkzf7ibxa6ax238zb2l5iw9nkgvzlh1v6l"))))
+        (base32 "1r2albqv2ygs58rwcldsx1mp2vy96j7k4yw5jjmvwgnxjmddq7wr"))))
     (build-system gnu-build-system)
     (native-inputs
      (list pkg-config))
diff --git a/gnu/packages/gettext.scm b/gnu/packages/gettext.scm
index d606acf798..5df30c4be3 100644
--- a/gnu/packages/gettext.scm
+++ b/gnu/packages/gettext.scm
@@ -120,13 +120,19 @@
                                                "coreutils-gnulib-tests.patch")))))
                               '())
 
+                       #$@(if (hurd-target?)
+                              #~((substitute*
+                                     "gettext-tools/gnulib-tests/Makefile.in"
+                                   ;; See 'coreutils' for the rationale.
+                                   ((" test-tls\\$\\(EXEEXT\\) ") " ")))
+                              '())
+
                        #t)))))
 
        ;; When tests fail, we want to know the details.
        #:make-flags #~'("VERBOSE=yes"
                         #$@(if (hurd-target?)
-                               ;; Linking to libgettextlib.so makes test-raise fail
-                               '("XFAIL_TESTS=test-raise")
+                               '("XFAIL_TESTS=test-perror2")
                                '()))))
     (home-page "https://www.gnu.org/software/gettext/")
     (synopsis
diff --git a/gnu/packages/gl.scm b/gnu/packages/gl.scm
index 00b04d0cc9..672a820686 100644
--- a/gnu/packages/gl.scm
+++ b/gnu/packages/gl.scm
@@ -587,30 +587,29 @@ from software emulation to complete hardware acceleration for modern GPUs.")
     (source (mesa-demos-source version))
     (build-system gnu-build-system)
     (inputs
-     `(("mesa" ,mesa)
-       ("glut" ,freeglut)
-       ("glew" ,glew)))
+     (list mesa freeglut glew))
     (native-inputs
      (list pkg-config))
     (arguments
-     '(#:phases
-       (modify-phases %standard-phases
-         (replace
-          'install
-          (lambda* (#:key outputs #:allow-other-keys)
-            (let ((out (assoc-ref outputs "out")))
-              (mkdir-p (string-append out "/bin"))
-              (for-each
-               (lambda (file)
-                 (copy-file file (string-append out "/bin/" (basename file))))
-               '("src/xdemos/glxdemo" "src/xdemos/glxgears"
-                 "src/xdemos/glxinfo" "src/xdemos/glxheads"))
-              #t))))))
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (replace 'install
+            (lambda* (#:key outputs #:allow-other-keys)
+              (let ((out #$output))
+                (mkdir-p (string-append out "/bin"))
+                (for-each (lambda (file)
+                            (copy-file file
+                                       (string-append out "/bin/"
+                                                      (basename file))))
+                          '("src/xdemos/glxdemo" "src/xdemos/glxgears"
+                            "src/egl/opengl/eglinfo"
+                            "src/xdemos/glxinfo" "src/xdemos/glxheads"))))))))
     (home-page "https://mesa3d.org/")
     (synopsis "Utility tools for Mesa")
     (description
-     "The mesa-utils package contains several utility tools for Mesa: glxdemo,
-glxgears, glxheads, and glxinfo.")
+     "The mesa-utils package contains several utility tools for Mesa: eglinfo,
+glxdemo, glxgears, glxheads, and glxinfo.")
     ;; glxdemo is public domain; others expat.
     (license (list license:expat license:public-domain))))
 
diff --git a/gnu/packages/glib.scm b/gnu/packages/glib.scm
index 61040c91e7..f85d5e3225 100644
--- a/gnu/packages/glib.scm
+++ b/gnu/packages/glib.scm
@@ -17,6 +17,7 @@
 ;;; Copyright © 2020 Jan (janneke) Nieuwenhuizen <janneke@gnu.org>
 ;;; Copyright © 2020 Arthur Margerit <ruhtra.mar@gmail.com>
 ;;; Copyright © 2021 Maxime Devos <maximedevos@telenet.be>
+;;; Copyright © 2022 Petr Hodina <phodina@protonmail.com>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -67,6 +68,7 @@
   #:use-module (gnu packages pkg-config)
   #:use-module (gnu packages python)
   #:use-module (gnu packages python-xyz)
+  #:use-module (gnu packages sqlite)
   #:use-module (gnu packages web)
   #:use-module (gnu packages xml)
   #:use-module (gnu packages xorg)
@@ -76,6 +78,7 @@
   #:use-module (guix build-system perl)
   #:use-module (guix build-system python)
   #:use-module (guix download)
+  #:use-module (guix git-download)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (guix packages)
   #:use-module (guix utils)
@@ -758,6 +761,59 @@ translated.")
 by GDBus included in Glib.")
     (license license:gpl2)))                     ; or Academic Free License 2.1
 
+(define-public libaccounts-glib
+  (package
+    (name "libaccounts-glib")
+    (version "1.25")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://gitlab.com/accounts-sso/libaccounts-glib")
+                    (commit (string-append "VERSION_" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "19rhk9f97m736d5ia26vfcbjp5kgi454558yhf9mrwm4iw5d9pk4"))))
+    (build-system meson-build-system)
+    (native-inputs (list dbus
+                         `(,glib "bin")
+                         gobject-introspection
+                         gtk-doc
+                         pkg-config
+                         vala))
+    (inputs (list check python python-pygobject))
+    (propagated-inputs (list glib libxml2 sqlite))
+    (arguments
+     (list #:tests? #f                  ;one test fails.
+           #:imported-modules `((guix build python-build-system)
+                                ,@%meson-build-system-modules)
+           #:modules '(((guix build python-build-system)
+                        #:select (python-version))
+                       (guix build meson-build-system)
+                       (guix build utils))
+           ;; don't try installing to python store path.
+           #:configure-flags
+           #~(list (string-append "-Dpy-overrides-dir="
+                                  #$output "/lib/python"
+                                  (python-version #$(this-package-input
+                                                     "python"))
+                                  "/site-packages/gi/overrides"))
+           #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (invoke "dbus-run-session" "--" "meson" "test"
+                                      "--print-errorlogs")))))))
+    (home-page "https://accounts-sso.gitlab.io/")
+    (synopsis "Accounts SSO (Single Sign-On) management library for GLib
+applications")
+    (description
+     "Accounts SSO is a framework for application developers who
+wish to acquire, use and store web account details and credentials.  It
+handles the authentication process of an account and securely stores the
+credentials and service-specific settings.")
+    (license license:lgpl2.1+)))
+
 (define libsigc++
   (package
     (name "libsigc++")
diff --git a/gnu/packages/gnome-xyz.scm b/gnu/packages/gnome-xyz.scm
index b7e10100fb..0368ccc223 100644
--- a/gnu/packages/gnome-xyz.scm
+++ b/gnu/packages/gnome-xyz.scm
@@ -55,6 +55,7 @@
   #:use-module (gnu packages bash)
   #:use-module (gnu packages build-tools)
   #:use-module (gnu packages check)
+  #:use-module (gnu packages freedesktop)
   #:use-module (gnu packages gettext)
   #:use-module (gnu packages glib)
   #:use-module (gnu packages gnome)
@@ -304,6 +305,59 @@ and products.  Plots is designed to integrate well with the GNOME desktop and
 takes advantage of modern hardware using OpenGL.")
     (license license:gpl3+)))
 
+(define-public portfolio
+  (package
+    (name "portfolio")
+    (version "0.9.14")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/tchx84/Portfolio")
+                    (commit (string-append "v" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "0h09v8lhz3kv6qmwjhx3gr7rp6ccfhrzm54gjnaixl4dcg9zddls"))))
+    (arguments
+     (list #:glib-or-gtk? #t
+           #:imported-modules `(,@%meson-build-system-modules
+                                (guix build python-build-system))
+           #:modules '((guix build meson-build-system)
+                       ((guix build python-build-system)
+                        #:prefix python:)
+                       (guix build utils))
+           #:phases #~(modify-phases %standard-phases
+                        (add-after 'install 'rename-executable
+                          (lambda _
+                            (with-directory-excursion (string-append #$output
+                                                                     "/bin")
+                              (symlink "dev.tchx84.Portfolio" "portfolio"))))
+                        (add-after 'glib-or-gtk-wrap 'python-and-gi-wrap
+                          (lambda* (#:key inputs outputs #:allow-other-keys)
+                            (wrap-program (search-input-file outputs
+                                                             "bin/dev.tchx84.Portfolio")
+                              `("GUIX_PYTHONPATH" =
+                                (,(getenv "GUIX_PYTHONPATH") ,(python:site-packages
+                                                               inputs
+                                                               outputs)))
+                              `("GI_TYPELIB_PATH" =
+                                (,(getenv "GI_TYPELIB_PATH")))))))))
+    (build-system meson-build-system)
+    (inputs (list bash-minimal python-pygobject gtk+ libhandy))
+    (native-inputs
+     (list desktop-file-utils
+           gettext-minimal
+           `(,glib "bin")
+           `(,gtk+ "bin")
+           python))
+    (home-page "https://github.com/tchx84/Portfolio")
+    (synopsis "Minimalist file manager for Linux mobile devices")
+    (description
+     "Portfolio is a minimalist file manager for those who want to use Linux
+mobile devices.  Tap to activate and long press to select, to browse, open,
+copy, move, delete, or edit your files.")
+    (license license:gpl3+)))
+
 (define-public gnome-shell-extension-unite-shell
   (package
     (name "gnome-shell-extension-unite-shell")
diff --git a/gnu/packages/gnome.scm b/gnu/packages/gnome.scm
index 3d942635a2..f81b44cca2 100644
--- a/gnu/packages/gnome.scm
+++ b/gnu/packages/gnome.scm
@@ -2594,6 +2594,11 @@ GNOME Desktop.")
            python-wrapper))             ;for tests
     (propagated-inputs
      (list gcr))
+
+    ;; XXX: There are concerning test failures on i686-linux and other 32-bit
+    ;; platforms: <https://gitlab.gnome.org/GNOME/gnome-keyring/-/issues/124>.
+    (supported-systems %64bit-supported-systems)
+
     (home-page "https://www.gnome.org")
     (synopsis "Daemon to store passwords and encryption keys")
     (description
@@ -4956,6 +4961,57 @@ GLibproxyResolver, and a GNOME GProxyResolver that uses the proxy information
 from the GSettings schemas in gsettings-desktop-schemas.")
     (license license:lgpl2.1+)))
 
+(define-public raider
+  (package
+    (name "raider")
+    (version "1.3.1")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/ADBeveridge/raider/")
+                    (commit (string-append "v" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "0ll9220d6qf9m7wdi5xhq69p8h8whs7l5h5nzdhlbn99qh5388bz"))))
+    (build-system meson-build-system)
+    (arguments
+     (list #:meson meson-0.63
+           #:phases
+           #~(modify-phases %standard-phases
+               (add-after 'unpack 'patch-paths
+                 (lambda* (#:key inputs #:allow-other-keys)
+                   (substitute* "data/com.github.ADBeveridge.Raider.gschema.xml"
+                     (("/usr/bin/shred")
+                      (which "shred")))))
+               (add-after 'install 'wrap-program
+                 (lambda* (#:key inputs outputs #:allow-other-keys)
+                   (wrap-program (string-append (assoc-ref outputs "out")
+                                                "/bin/raider")
+                     `("GSETTINGS_SCHEMA_DIR" =
+                       (,(string-append (assoc-ref outputs "out")
+                                        "/share/glib-2.0/schemas")))))))))
+    (native-inputs
+     (list gettext-minimal
+           pkg-config
+           cmake
+           `(,glib "bin")
+           desktop-file-utils
+           itstool
+           gobject-introspection
+           blueprint-compiler
+           `(,gtk "bin")))
+    (inputs
+     (list libadwaita
+           gtk))
+    (home-page "https://github.com/ADBeveridge/raider")
+    (synopsis "Securely delete your files")
+    (description
+     "Raider is a simple shredding program built for GNOME.  Also known as
+File Shredder, it uses the GNU Core Utility called shred to securely delete
+files.")
+    (license license:gpl3+)))
+
 (define-public rest
   (package
     (name "rest")
@@ -9671,7 +9727,9 @@ shared object databases, search tools and indexing.")
                                   name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1cncyiyh79w1id6a6s2f0rxmgwl65lp4ml4afa0z35jrnwp2s8cr"))))
+                "1cncyiyh79w1id6a6s2f0rxmgwl65lp4ml4afa0z35jrnwp2s8cr"))
+              (patches
+               (search-patches "nautilus-extension-search-path.patch"))))
     (build-system meson-build-system)
     (arguments
      (list
@@ -9685,27 +9743,6 @@ shared object databases, search tools and indexing.")
               (substitute* "test/automated/displayless/meson.build"
                 (("^foreach t: tracker_tests" all)
                  (string-append "tracker_tests = []\n" all)))))
-          (add-after 'unpack 'make-extensible
-            (lambda _
-              (substitute* "src/nautilus-module.c"
-                (("static gboolean initialized = FALSE;" all)
-                 (string-append all "
-const char *extension_path;
-char **extension_dirs, **d;
-")
-                 )
-                (("load_module_dir \\(NAUTILUS_EXTENSIONDIR\\);" all)
-                 (string-append all
-                                "
-extension_path = g_getenv (\"NAUTILUS_EXTENSION_PATH\");
-if (extension_path)
-{
-    extension_dirs = g_strsplit (extension_path, \":\", -1);
-    for (d = extension_dirs; d != NULL && *d != NULL; d++)
-        load_module_dir(*d);
-    g_strfreev(extension_dirs);
-}
-")))))
           (add-after 'unpack 'skip-gtk-update-icon-cache
             ;; Don't create 'icon-theme.cache'.
             (lambda _
diff --git a/gnu/packages/gnupg.scm b/gnu/packages/gnupg.scm
index 210b1ab8b3..064b775ab1 100644
--- a/gnu/packages/gnupg.scm
+++ b/gnu/packages/gnupg.scm
@@ -431,6 +431,19 @@ and every application benefits from this.")
     (properties '((ftp-server . "ftp.gnupg.org")
                   (ftp-directory . "/gcrypt/gpgme")))))
 
+;; TODO: Merge with gpgme in the next rebuild cycle.
+(define-public gpgme-1.18
+  (package
+    (inherit gpgme)
+    (version "1.18.0")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://gnupg/gpgme/gpgme-"
+                                  version ".tar.bz2"))
+              (sha256
+               (base32
+                "17hfigfnq6xz45b5xrp299f68b5mwx0aysd51sx5v4nf8yp4w79n"))))))
+
 (define-public qgpgme
   (package
     (inherit gpgme)
@@ -459,6 +472,16 @@ QGpgME was originally developed as part of libkleo and incorporated into
 gpgpme starting with version 1.7.")
     (license license:gpl2+))) ;; Note: this differs from gpgme
 
+;; TODO: Merge with qgpgme in the next rebuild cycle.
+(define-public qgpgme-1.18
+  (package
+    (inherit qgpgme)
+    (version (package-version gpgme-1.18))
+    (source (package-source gpgme-1.18))
+    (inputs
+     (modify-inputs (package-inputs qgpgme)
+       (replace "gpgme" gpgme-1.18)))))
+
 (define-public guile-gcrypt
   (package
     (name "guile-gcrypt")
diff --git a/gnu/packages/golang.scm b/gnu/packages/golang.scm
index 2ed4c7a73c..e848074cb4 100644
--- a/gnu/packages/golang.scm
+++ b/gnu/packages/golang.scm
@@ -2485,6 +2485,101 @@ web framework
 @end itemize")
     (license license:expat)))
 
+(define-public go-github-com-nathan-osman-go-sunrise
+  (let ((commit "c8f9f1eb869135f07378e7e3c5ec7a005f806c73")
+        (revision "0"))
+    (package
+      (name "go-github-com-nathan-osman-go-sunrise")
+      (version (git-version "1.1.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/nathan-osman/go-sunrise")
+               (commit commit)))
+         (file-name (git-file-name name version))
+         (sha256
+          (base32
+           "017zwzx05r5spxcs07dp6bnh7waknzsd819k7aqd8kr819v3x9in"))))
+      (build-system go-build-system)
+      (arguments
+       (list #:import-path "github.com/nathan-osman/go-sunrise"))
+      (home-page "https://github.com/nathan-osman/go-sunrise")
+      (synopsis "Calculate sunrise and sunset times in Go")
+      (description
+       "This package provides a Go library for calculating sunrise and
+sunset times from geographical coordinates and a date.")
+      (license license:expat))))
+
+(define-public go-github-com-hebcal-gematriya
+  (let ((commit "fe3043f73e415eb82727701d10f2fb40f87675e9")
+        (revision "0"))
+    (package
+      (name "go-github-com-hebcal-gematriya")
+      (version (git-version "1.0.1" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/hebcal/gematriya")
+               (commit commit)))
+         (file-name (git-file-name name version))
+         (sha256
+          (base32
+           "0xmnb2i80dy380yv8c4pd04bbyqgbc7c40p8hz1vqj2lhbm6jabf"))))
+      (build-system go-build-system)
+      (arguments
+       (list #:import-path "github.com/hebcal/gematriya"))
+      (home-page "https://github.com/hebcal/gematriya")
+      (synopsis "Print numbers as Hebrew letters in Go")
+      (description
+       "This package provides a Go library for printing numbers as
+Hebrew letters.")
+      (license license:bsd-2))))
+
+(define-public go-github-com-hebcal-hebcal-go
+  (let ((commit "d42e881860cfc9e8249fc79f268091c3c4d36b0d")
+        (revision "0"))
+    (package
+      (name "go-github-com-hebcal-hebcal-go")
+      (version (git-version "0.9.11" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/hebcal/hebcal-go")
+               (commit commit)))
+         (file-name (git-file-name name version))
+         (sha256
+          (base32
+           "1m9akb8pwxchpaci05gambshrzw626gsrfhl25f36vjl7mq5292n"))))
+      (build-system go-build-system)
+      (arguments
+       (list #:import-path "github.com/hebcal/hebcal-go"
+             ;; Source-only package
+             #:tests? #f
+             #:phases
+             #~(modify-phases %standard-phases
+                 ;; Source-only package
+                 (delete 'build))))
+      (native-inputs
+       (list go-github-com-stretchr-testify))
+      (propagated-inputs
+       (list go-github-com-hebcal-gematriya
+             go-github-com-nathan-osman-go-sunrise))
+      (home-page "https://github.com/hebcal/hebcal-go")
+      (synopsis "Go library for the Hebcal perpetual Jewish calendar")
+      (description
+       "This package provides a library for conversion between Hebrew
+and Gregorian dates, and generation of lists of Jewish holidays for
+a given year.  Shabbat and holiday candle lighting and havdalah times
+are approximated based on location.
+
+Torah readings, Daf Yomi, and counting of the Omer can also be
+specified.  Algorithms are included to calculate yahrzeits, birthdays,
+and anniversaries.")
+      (license license:gpl2+))))
+
 (define-public go-github-com-aws-sdk
   (package
     (name "go-github-com-aws-sdk")
diff --git a/gnu/packages/gstreamer.scm b/gnu/packages/gstreamer.scm
index a92588a9e2..e46bf7b741 100644
--- a/gnu/packages/gstreamer.scm
+++ b/gnu/packages/gstreamer.scm
@@ -791,6 +791,14 @@ model to base your own plug-in on, here it is.")
                   ;; FIXME: Why is this failing.
                   ((".*elements/dash_mpd\\.c.*") "")
 
+                  ;; This test is flaky on at least some architectures.
+                  ;; https://gitlab.freedesktop.org/gstreamer/gstreamer/-/issues/1244
+                  #$@(if (member (%current-system)
+                                 '("i686-linux" "aarch64-linux"))
+                         `((("'elements/camerabin\\.c'\\]\\],")
+                            "'elements/camerabin.c'], true, ],"))
+                         '())
+
                   ;; These tests are flaky and occasionally time out:
                   ;; https://gitlab.freedesktop.org/gstreamer/gst-plugins-bad/-/issues/932
                   ((".*elements/curlhttpsrc\\.c.*") "")
diff --git a/gnu/packages/gtk.scm b/gnu/packages/gtk.scm
index 56104b2124..ad34dd51ec 100644
--- a/gnu/packages/gtk.scm
+++ b/gnu/packages/gtk.scm
@@ -32,6 +32,7 @@
 ;;; Copyright © 2022 Zhu Zihao <all_but_last@163.com>
 ;;; Copyright © 2022 Benjamin Slade <slade@lambda-y.net>
 ;;; Copyright © 2022 Denis 'GNUtoo' Carikli <GNUtoo@cyberdimension.org>
+;;; Copyright © 2022 Petr Hodina <phodina@protonmail.com>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -117,6 +118,43 @@
   #:use-module (srfi srfi-26)
   #:use-module (ice-9 match))
 
+(define-public appmenu-gtk-module
+  (package
+    (name "appmenu-gtk-module")
+    (version "0.7.6")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://gitlab.com/vala-panel-project/vala-panel-appmenu")
+             (commit version)))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32
+         "1ywpygjwlbli65203ja2f8wwxh5gbavnfwcxwg25v061pcljaqmm"))))
+    (build-system meson-build-system)
+    (arguments
+     (list
+      #:glib-or-gtk? #t
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'fix-install-gtk-module
+            (lambda* _
+              (substitute*
+                  "subprojects/appmenu-gtk-module/src/gtk-3.0/meson.build"
+                (("gtk3.get_pkgconfig_variable\\('libdir'\\)")
+                 #$output)))))))
+    (native-inputs
+     (list `(,glib "bin") vala pkg-config))
+    (inputs
+     (list gtk+ libwnck))
+    (synopsis "Application Menu applet")
+    (description
+     "This package provides a global menu applet for use with desktop panels
+such as mate-panel and xfce4-panel.")
+    (home-page "https://gitlab.com/vala-panel-project/vala-panel-appmenu")
+    (license (list license:lgpl3))))
+
 (define-public atk
   (package
     (name "atk")
diff --git a/gnu/packages/guile-xyz.scm b/gnu/packages/guile-xyz.scm
index 62bcfb6a56..b1620618eb 100644
--- a/gnu/packages/guile-xyz.scm
+++ b/gnu/packages/guile-xyz.scm
@@ -4189,7 +4189,7 @@ models and also supports a rich set of boolean query operators.")
            perl
            pkg-config))
     (propagated-inputs
-     (list guile-gcrypt))
+     (list guile2.2-gcrypt))
     (home-page "https://github.com/o-nly/torrent")
     (synopsis "Torrent library for GNU Guile")
     (description "This package provides facilities for working with
diff --git a/gnu/packages/heads.scm b/gnu/packages/heads.scm
index d5e36b9b3c..212849f2a9 100644
--- a/gnu/packages/heads.scm
+++ b/gnu/packages/heads.scm
@@ -172,6 +172,7 @@ done
     (build-system trivial-build-system)
     (arguments
      `(#:modules ((guix build utils)
+                  (guix build syscalls)
                   (guix cpio))
        #:builder (begin
                    (use-modules (guix build utils)
diff --git a/gnu/packages/kde-frameworks.scm b/gnu/packages/kde-frameworks.scm
index 214420c101..aaa5a82d5f 100644
--- a/gnu/packages/kde-frameworks.scm
+++ b/gnu/packages/kde-frameworks.scm
@@ -51,6 +51,7 @@
   #:use-module (gnu packages compression)
   #:use-module (gnu packages databases)
   #:use-module (gnu packages docbook)
+  #:use-module (gnu packages ebook)
   #:use-module (gnu packages flex)
   #:use-module (gnu packages freedesktop)
   #:use-module (gnu packages gettext)
@@ -62,9 +63,11 @@
   #:use-module (gnu packages graphics)
   #:use-module (gnu packages graphviz)
   #:use-module (gnu packages gstreamer)
+  #:use-module (gnu packages gtk)
   #:use-module (gnu packages image)
   #:use-module (gnu packages iso-codes)
   #:use-module (gnu packages kerberos)
+  #:use-module (gnu packages kde)
   #:use-module (gnu packages kde-plasma)
   #:use-module (gnu packages libcanberra)
   #:use-module (gnu packages libreoffice)
@@ -82,10 +85,13 @@
   #:use-module (gnu packages qt)
   #:use-module (gnu packages textutils)
   #:use-module (gnu packages tls)
+  #:use-module (gnu packages text-editors)
   #:use-module (gnu packages version-control)
   #:use-module (gnu packages video)
+  #:use-module (gnu packages vulkan)
   #:use-module (gnu packages web)
   #:use-module (gnu packages xml)
+  #:use-module (gnu packages xdisorg)
   #:use-module (gnu packages xorg)
   #:use-module (srfi srfi-1))
 
@@ -173,6 +179,39 @@ modules provided by CMake to find common software.  In addition, it provides
 common build settings used in software produced by the KDE community.")
     (license license:bsd-3)))
 
+(define-public kquickcharts
+  (package
+    (name "kquickcharts")
+    (version "5.96.0")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/frameworks/"
+                                  (version-major+minor version)
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1sd9mfxk72xfa1kz77s7z312scfm0vwvvgmyi4pypb9cs7d9dq3j"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (system "Xvfb :1 -screen 0 640x480x24 &")
+                              (setenv "DISPLAY" ":1")
+                              (setenv "QT_QPA_PLATFORM" "offscreen")
+                              (invoke "ctest")))))))
+    (inputs (list qtbase-5 qtdeclarative-5 qtquickcontrols2-5
+                  xorg-server-for-tests))
+    (native-inputs (list extra-cmake-modules glslang pkg-config))
+    (home-page "https://api.kde.org/frameworks/kquickcharts/html/index.html")
+    (synopsis "QtQuick plugin providing high-performance charts")
+    (description
+     "The Quick Charts module provides a set of charts that can be
+used from QtQuick applications for both simple display of data as well as
+continuous display of high-volume data.")
+    (license (list license:lgpl2.1 license:lgpl3))))
+
 (define-public phonon
   (package
     (name "phonon")
@@ -194,18 +233,18 @@ common build settings used in software produced by the KDE community.")
     (inputs
      (list qtbase-5))
     (arguments
-     `(#:configure-flags
-       '("-DCMAKE_CXX_FLAGS=-fPIC"
-         "-DPHONON_BUILD_PHONON4QT5=ON")
-       #:phases
-       (modify-phases %standard-phases
-         (add-before 'install 'patch-installdir
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             (let ((regex (string-append "(INSTALL DESTINATION \")"
-                                         (assoc-ref inputs "qtbase"))))
-               (substitute* "cmake_install.cmake"
-                 ((regex all dest)
-                  (string-append dest (assoc-ref outputs "out"))))))))))
+     (list #:configure-flags
+           #~'("-DCMAKE_CXX_FLAGS=-fPIC"
+               "-DPHONON_BUILD_PHONON4QT5=ON")
+           #:phases
+           #~(modify-phases %standard-phases
+               (add-before 'install 'patch-installdir
+                 (lambda* (#:key inputs outputs #:allow-other-keys)
+                   (let ((regex (string-append "(INSTALL DESTINATION \")"
+                                               #$(this-package-input "qtbase"))))
+                     (substitute* "cmake_install.cmake"
+                       ((regex all dest)
+                        (string-append dest #$output)))))))))
     (home-page "https://community.kde.org/Phonon")
     (synopsis "KDE's multimedia library")
     (description "KDE's multimedia library.")
@@ -228,8 +267,7 @@ common build settings used in software produced by the KDE community.")
     (native-inputs
      (list extra-cmake-modules pkg-config qttools-5))
     (inputs
-     (list qtbase-5
-           phonon
+     (list phonon
            qtbase-5
            qtx11extras
            gstreamer
@@ -254,7 +292,7 @@ Phonon-GStreamer is a backend based on the GStreamer multimedia library.")
 (define-public attica
   (package
     (name "attica")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -263,7 +301,7 @@ Phonon-GStreamer is a backend based on the GStreamer multimedia library.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1xlg2sbfd45p9dw0sprpk0fancasp4idxacsf5xksf2ddn2crzp7"))))
+                "0w1w6w2jia1q32jnn2dhyxmkq64ha1dcbsqj233v4f224rp3aknp"))))
     (build-system cmake-build-system)
     (arguments
      `(#:phases
@@ -294,7 +332,7 @@ http://freedesktop.org/wiki/Specifications/open-collaboration-services/")
 (define-public bluez-qt
   (package
     (name "bluez-qt")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -303,26 +341,24 @@ http://freedesktop.org/wiki/Specifications/open-collaboration-services/")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0yc7mq9bnanp5dfv43vp8wpqw5l8qh4aahqpi9sid7jmd6sbywl2"))))
+                "0h2k2qiskn921cpni5rs7x5ahric6dlllwsrk77akpi4xcsrip2g"))))
     (build-system cmake-build-system)
     (native-inputs
      (list dbus extra-cmake-modules))
     (inputs
-     ;; TODO: qtdeclarative-5 (yields one failing test)
-     (list qtbase-5))
+     (list qtdeclarative-5
+           qtbase-5))
     (arguments
      (list #:configure-flags
            #~(list (string-append
                     "-DUDEV_RULES_INSTALL_DIR=" #$output "/lib/udev/rules.d"))
-           ;; TODO: Make tests pass: DBUS_FATAL_WARNINGS=0 still yields 7/8 tests
-           ;; failing.  When running after install, tests hang.
-           #:phases
-            '(modify-phases %standard-phases
-              (replace 'check
-                (lambda* (#:key tests? #:allow-other-keys)
-                  (when tests?
-                    (setenv "DBUS_FATAL_WARNINGS" "0")
-                    (invoke "dbus-launch" "ctest")))))))
+	#:phases
+        #~(modify-phases %standard-phases
+            (replace 'check
+              (lambda* (#:key tests? #:allow-other-keys)
+                (when tests?
+                  (setenv "DBUS_FATAL_WARNINGS" "0")
+                  (invoke "dbus-launch" "ctest" "-E" "bluezqt-qmltests")))))))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "QML wrapper for BlueZ")
     (description "bluez-qt is a Qt-style library for accessing the bluez
@@ -332,24 +368,33 @@ Bluetooth stack.  It is used by the KDE Bluetooth stack, BlueDevil.")
 (define-public breeze-icons
   (package
     (name "breeze-icons")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
-              (uri (string-append
-                    "mirror://kde/stable/frameworks/"
-                    (version-major+minor version) "/"
-                    name "-" version ".tar.xz"))
+              (uri (string-append "mirror://kde/stable/frameworks/"
+                                  (version-major+minor version)
+                                  "/" name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1ij723qy6xfkys8a9vp2ll2z2yp7667hfw559gi8cxn825hjx823"))))
+                "0a3zvmhcfsnxv0jpyjny3sl769p99psadl1872v0qlkax47pvsjp"))))
     (build-system cmake-build-system)
     (native-inputs
-     (list extra-cmake-modules fdupes
-           python python-lxml)) ;; For 24x24 icon generation
-    (inputs
-     (list qtbase-5))
-    (arguments ;; fails because duplicate icons exist. TODO: try fix this.
-     `(#:tests? #f))
+     (list extra-cmake-modules
+           fdupes
+           `(,gtk+ "bin")
+           python
+           python-lxml))                ;for 24x24 icon generation
+    (inputs (list qtbase-5))
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (add-after 'install 'update-cache
+                          (lambda* _
+                            (invoke "gtk-update-icon-cache"
+                                    (string-append #$output
+                                                   "/share/icons/breeze"))
+                            (invoke "gtk-update-icon-cache"
+                                    (string-append #$output
+                                                   "/share/icons/breeze-dark")))))))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "Default KDE Plasma 5 icon theme")
     (description "Breeze provides a freedesktop.org compatible icon theme.
@@ -362,7 +407,7 @@ It is the default icon theme for the KDE Plasma 5 desktop.")
 (define-public kapidox
   (package
     (name "kapidox")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -371,7 +416,7 @@ It is the default icon theme for the KDE Plasma 5 desktop.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1w5h4xwscix0yjn8d0rcjd7hlmrnbmkjg20diqjabb5wcxsrjiwi"))))
+                "1k2qk8ibv5dqdhkn2992n8rlmslpmngz83hxb7zrh3pkphdg8v2n"))))
     (build-system python-build-system)
     (arguments
      `(#:tests? #f  ; has no test target
@@ -402,26 +447,30 @@ documentation.")
 (define-public karchive
   (package
     (name "karchive")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
-              (uri (string-append
-                    "mirror://kde/stable/frameworks/"
-                    (version-major+minor version) "/"
-                    name "-" version ".tar.xz"))
+              (uri (string-append "mirror://kde/stable/frameworks/"
+                                  (version-major+minor version)
+                                  "/" name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1bra1q225xhh8dilwmzc0jgnj5m3dmi4nkz4y8f42si97b4xxxf5"))))
+                "1ipj7j1iw6g56z0qppji38h6qwbs05piiqqbsw8hdbf96l6cdiq2"))))
     (build-system cmake-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (invoke "ctest" "-E" "karchivetest")))))))
     (native-inputs
-     (list extra-cmake-modules))
-           ;; pkg-config ;; For zstd
+     (list extra-cmake-modules pkg-config))
     (inputs
-     (list bzip2 qtbase-5 xz zlib))
-           ;; `(,zstd "lib")  ;; FIXME: Tests fail with zstd
+     (list bzip2 qtbase-5 xz zlib `(,zstd "lib")))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "Qt 5 addon providing access to numerous types of archives")
-    (description "KArchive provides classes for easy reading, creation and
+    (description
+     "KArchive provides classes for easy reading, creation and
 manipulation of @code{archive} formats like ZIP and TAR.
 
 It also provides transparent compression and decompression of data, like the
@@ -435,7 +484,7 @@ GZip format, via a subclass of QIODevice.")
 (define-public kcalendarcore
   (package
     (name "kcalendarcore")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -444,7 +493,7 @@ GZip format, via a subclass of QIODevice.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "181yif830v4gg7nw9s15pvgfm98rmm6xwi2xxy3nxg7nkp14vs5k"))))
+                "16kclspsjzld9n07z1i8li2pc91ihpqhbk46a4s92nsihs2dkayk"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules perl tzdata-for-tests))
@@ -475,7 +524,7 @@ and the older vCalendar.")
 (define-public kcodecs
   (package
     (name "kcodecs")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -484,7 +533,7 @@ and the older vCalendar.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "05266wjxmzf3qpb2xwlm40cr9h266l5r9dqww81m8bq856pf8ivi"))))
+                "0n10r7s9r25xp7vlym41qi421kld00niig73yark7yghj0r41jcz"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules gperf qttools-5))
@@ -509,7 +558,7 @@ Internet).")
 (define-public kconfig
   (package
     (name "kconfig")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -518,7 +567,7 @@ Internet).")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1xa8xxm2x9783fqb26wyvg1mp6ybjikngznqdhsk9slhaca73yhz"))))
+                "15m2bggfr682q68dym7nzmvz7q7pwarzijad1wj0r5cs62l3bkjy"))))
     (build-system cmake-build-system)
     (native-inputs
      (list dbus extra-cmake-modules inetutils qttools-5
@@ -614,7 +663,7 @@ many more.")
 (define-public kdbusaddons
   (package
     (name "kdbusaddons")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -623,7 +672,7 @@ many more.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1y0fd0a1nwgchsk3vx8hvvkw96f0l0533g57xakq4j4xkvxd8l3y"))))
+                "0fwdmlnci2xn5pi1ywgia3xka3zsh6gl6xpx1gvql7lczk1y490a"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules dbus qttools-5))
@@ -631,8 +680,8 @@ many more.")
      (list qtbase-5 qtx11extras kinit-bootstrap))
     ;; kinit-bootstrap: kinit package which does not depend on kdbusaddons.
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
+     (list #:phases
+       #~(modify-phases %standard-phases
          (add-before 'configure 'patch-source
           (lambda* (#:key inputs #:allow-other-keys)
             ;; look for the kdeinit5 executable in kinit's store directory,
@@ -640,7 +689,8 @@ many more.")
             (substitute* "src/kdeinitinterface.cpp"
               (("<< QCoreApplication::applicationDirPath..")
                (string-append
-                "<< QString::fromUtf8(\"" (assoc-ref inputs "kinit") "/bin\")" )))))
+                "<< QString::fromUtf8(\"/" (dirname (search-input-file inputs
+                "bin/kdeinit5")) "\")" )))))
          (replace 'check
            (lambda* (#:key tests? #:allow-other-keys)
              (when tests?
@@ -657,7 +707,7 @@ as well as an API to create KDED modules.")
 (define-public kdnssd
   (package
     (name "kdnssd")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -666,7 +716,7 @@ as well as an API to create KDED modules.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1d3jq64gyj3bc3sf46gnpbmjrm809hva47z7fkwkk9i2lmnmy70w"))))
+                "0wcjq0g1cdjz9npy31i4rqbx85a95f15w71aamhm8x82l8nysv4g"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -712,7 +762,7 @@ replace the other outdated Graphviz tools.")
 (define-public kguiaddons
   (package
     (name "kguiaddons")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -721,7 +771,7 @@ replace the other outdated Graphviz tools.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "028kn9lcvzv8f8b17a3clki7013dmhhcp1l9svvf6hydv97vkfbv"))))
+                "022qf858khdqklq117i223ihpw8mvdcbcfn8cwqmn2cv9qnfxnqj"))))
     (build-system qt-build-system)
     ;; TODO: Build packages for the Python bindings.  Ideally this will be
     ;; done for all versions of python guix supports.  Requires python,
@@ -740,7 +790,7 @@ interfaces in the areas of colors, fonts, text, images, keyboard input.")
 (define-public kholidays
   (package
     (name "kholidays")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -748,7 +798,7 @@ interfaces in the areas of colors, fonts, text, images, keyboard input.")
                     (version-major+minor version) "/"
                     name "-" version ".tar.xz"))
        (sha256
-        (base32 "0rcd8k2x1w6jszxj18pkzimn5q4v2k7zs9x1pfwszn7xl59b3n4k"))))
+        (base32 "0ysw52wiyxrkprn0gis85nphpfl1wdb4439i66dfmg7s9nyqpzp0"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -763,7 +813,7 @@ other special events for a geographical region.")
 (define-public ki18n
   (package
     (name "ki18n")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -772,7 +822,7 @@ other special events for a geographical region.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1jry8bdjgxkcqln7awkj3k8996lh76vya2mf5kwpyxagk6vmr0gy"))))
+                "0b3r53v2ybhlyqpkjv98dv2w9q49yqqxk9qzbyc4mm7ypq4hvl47"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list gettext-minimal python))
@@ -804,7 +854,7 @@ translation scripting.")
 (define-public kidletime
   (package
     (name "kidletime")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -813,7 +863,7 @@ translation scripting.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "13piv607n9hmlbd7kkhl7b1wcxj1jq2b5386c6pxrz5caxjwgnmd"))))
+                "1jdbjkishqnlzz1qrzyg92xnlsl7w89dmrh0zhzaj9bnr5a3icck"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config))
@@ -833,7 +883,7 @@ or user activity.")
   ;; plasma-framework which is tier 3.
   (package
     (name "kirigami")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -842,7 +892,7 @@ or user activity.")
                     "kirigami2-" version ".tar.xz"))
               (sha256
                (base32
-                "12ir4q9njl60b242j9raj1xsjs0cizsk7bixwb1hssfn6fzpzqkv"))))
+                "1l0ggwrprmg5n5y3gxv7h4593fg87d7naxkf30603kkavq0hgks6"))))
     (properties `((upstream-name . "kirigami2")))
     (build-system cmake-build-system)
     (native-inputs
@@ -868,7 +918,7 @@ of applications that follow the Kirigami Human Interface Guidelines.")
 (define-public kitemmodels
   (package
     (name "kitemmodels")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -877,7 +927,7 @@ of applications that follow the Kirigami Human Interface Guidelines.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1j6kffvgbd07zzzv0kab8mbwa69fmw4b8jczd0wzvmp56idsfc2v"))))
+                "1z9swjmll833jxy2ym63zzgi9vl8ld79mgypndqszsrd4mfsbs16"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -918,7 +968,7 @@ model to observers
 (define-public kitemviews
   (package
     (name "kitemviews")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -927,7 +977,7 @@ model to observers
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1wr62z6jwlg40m8kl9bpiyzkyjmsqx0fhgwc01192k58nl2696lb"))))
+                "176gqlinsvdgkbg7kr4qd97mnvcnbymrkcs9kg6hm75qzxcaj8dj"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -943,7 +993,7 @@ to flat and hierarchical lists.")
 (define-public kplotting
   (package
     (name "kplotting")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -952,7 +1002,7 @@ to flat and hierarchical lists.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1yqx260r3dzcinp8s685yzp5f2ihc0s1csckb9zv7z1bzljkn3h9"))))
+                "0hnzyl1x6acv1psdgsa9prpvnm12j71x6w6wbs1b0fl9bv5zw222"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -970,7 +1020,7 @@ pixel units.")
 (define-public ksyntaxhighlighting
   (package
     (name "ksyntaxhighlighting")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -979,7 +1029,7 @@ pixel units.")
                     "syntax-highlighting-" version ".tar.xz"))
               (sha256
                (base32
-                "176prghxfrb7i68jacmq9vkl7j9arsn6gnkzyc2hlkph35js3zqs"))))
+                "092ilbhhs8xaqblc9w1xksapdzvqyazz8lj011wz4762p1nagiq2"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules perl qttools-5
@@ -1037,7 +1087,7 @@ protocols used in KDE Plasma.")
 (define-public kwayland
   (package
     (name "kwayland")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1047,12 +1097,17 @@ protocols used in KDE Plasma.")
               (patches (search-patches "kwayland-skip-flaky-test.patch"))
               (sha256
                (base32
-                "0dcnsiippwxvwvf1gvp75lx97c4nydzn3x1l8lfy86w9lfslw7zb"))))
+                "0c0953gm63xhrqb7aspvf28wi7x31mrgaid23dw5gqphkbgis5qw"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config))
     (inputs
-     (list qtbase-5 plasma-wayland-protocols qtwayland-5 wayland wayland-protocols))
+     (list libxkbcommon
+           plasma-wayland-protocols
+           qtbase-5
+           qtwayland-5
+           wayland
+           wayland-protocols))
     (arguments
      (list
       ;; Tests spawn Wayland sessions that cannot run in parallel.
@@ -1075,7 +1130,7 @@ represented by a QPoint or a QSize.")
 (define-public kwidgetsaddons
   (package
     (name "kwidgetsaddons")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1084,7 +1139,7 @@ represented by a QPoint or a QSize.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1igbkrn8qaalan0lyn8r2gqv5v3rwbmb3xv3w26yw77vwp0n789r"))))
+                "117wki4w2bs1d2pjhi5qpb2b3qhhva6fq9gikba5fb6980kmdayr"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5 xorg-server-for-tests))
@@ -1110,7 +1165,7 @@ configuration pages, message boxes, and password requests.")
 (define-public kwindowsystem
   (package
     (name "kwindowsystem")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1119,7 +1174,7 @@ configuration pages, message boxes, and password requests.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1ilb3zl3mlndfrqz6gi28x6qqqs45l65d0wmy3lk07lppcw3wxzx"))))
+                "02l7xmxcilmrxpkkid4m9srl0d8ymqgwpw5j80w3g57p0rahwjl1"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules
@@ -1137,13 +1192,6 @@ configuration pages, message boxes, and password requests.")
     (arguments
      `(#:phases
        (modify-phases %standard-phases
-         (add-before 'check 'blacklist-failing-tests
-           (lambda _
-             ;; Blacklist a failing test-functions. FIXME: Make it pass.
-             (with-output-to-file "autotests/BLACKLIST"
-               (lambda _
-                 (display "[testGroupLeader]\n*\n")
-                 (display "[testClientMachine]\n*\n"))))) ;; requires network
          (replace 'check
            (lambda* (#:key tests? #:allow-other-keys)
              ;; The test suite requires a running window anager
@@ -1155,8 +1203,7 @@ configuration pages, message boxes, and password requests.")
                (system "openbox &")
                (setenv "CTEST_OUTPUT_ON_FAILURE" "1")
                (setenv "DBUS_FATAL_WARNINGS" "0")
-               (invoke "dbus-launch" "ctest" "-E"
-                       "kwindowsystem-kwindowsystemplatformwaylandtest")))))))
+               (invoke "dbus-launch" "ctest")))))))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "KDE access to the windowing system")
     (description "KWindowSystem provides information about and allows
@@ -1174,7 +1221,7 @@ lower level classes for interaction with the X Windowing System.")
 (define-public modemmanager-qt
   (package
     (name "modemmanager-qt")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1183,7 +1230,7 @@ lower level classes for interaction with the X Windowing System.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1rbiqh1sj328cy7flz9pw6vbvgiy3vyv6xp3fk4xv91sxviz1mhd"))))
+                "0gk4jy3r1451a2dajhnz6lin4lfawc4qdlxp7n7m43ca4d89h13k"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules dbus pkg-config))
@@ -1211,7 +1258,7 @@ messages.")
 (define-public networkmanager-qt
   (package
     (name "networkmanager-qt")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1220,7 +1267,7 @@ messages.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1gyvgy0wl00asg9bkhjgvqnz32xmazvazcarh3p0640jy2fjrzfz"))))
+                "0s1h02v9k8nyl30mw7gayzvpb8bnzzp9crcfqpry7rf02rxv9idw"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules dbus pkg-config))
@@ -1249,7 +1296,7 @@ which are used in DBus communication.")
 (define-public oxygen-icons
   (package
     (name "oxygen-icons")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1258,7 +1305,7 @@ which are used in DBus communication.")
                     name "5" "-" version ".tar.xz"))
               (sha256
                (base32
-                "1f3fj6zr5iygb3s6f8vq2ayy749gxlx5j9h6v2zmkbf4m96sfmq5"))))
+                "03wk52hqrgj0r73nb4yiq7rnmdn4rrqzrj3cdzbg3flkw5r7wbbq"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules fdupes))
@@ -1273,7 +1320,7 @@ which are used in DBus communication.")
 (define-public prison
   (package
     (name "prison")
-    (version "5.96.0")
+    (version "5.98.0")
     (source
      (origin
        (method url-fetch)
@@ -1281,7 +1328,7 @@ which are used in DBus communication.")
                            (version-major+minor version) "/"
                            name "-" version ".tar.xz"))
        (sha256
-        (base32 "1kzl8rbyj9ik83p1qb8jl32vr06vkzzvr1hpasj50sg3ajq8a9xs"))))
+        (base32 "1ppqm1f06q8fc1ncvzn9a133npmvlh1qxgvvbpwn6m0a8cr7ac6w"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1323,7 +1370,7 @@ libpulse.")
 (define-public qqc2-desktop-style
   (package
     (name "qqc2-desktop-style")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1332,7 +1379,7 @@ libpulse.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0ff9vd34wss9na2m3gzm8wc2bwq0flda6bv6yqygv5iallw2lz88"))))
+                "1af7izd4k220dzngf1nwgcw0bi7vl772lpjrqd9fp9rijh74dx7d"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config))
@@ -1344,7 +1391,9 @@ libpulse.")
            kirigami
            qtbase-5
            qtdeclarative-5
-           qtquickcontrols2-5))
+           qtquickcontrols2-5
+           qtx11extras ; optional
+           sonnet)) ; optional
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "QtQuickControls2 style that integrates with the desktop")
     (description "This is a style for QtQuickControls2 which is using
@@ -1356,7 +1405,7 @@ feel.")
 (define-public solid
   (package
     (name "solid")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1365,7 +1414,7 @@ feel.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0j64glc1g7mwy2ysaj09w5f7sd2992h91ncknk9gpfsrxhpm814i"))))
+                "14bf2k40skhyhrmgyyscg7psm1a8klf4z696pimlwjjhnawjfr06"))))
     (build-system cmake-build-system)
     (arguments
      `(#:phases
@@ -1390,7 +1439,7 @@ system.")
 (define-public sonnet
   (package
     (name "sonnet")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1399,7 +1448,7 @@ system.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0i0gksdkfyl8hfbqgrgklqanbvfm3h9gjnv42p2qq40b0zjj0sh4"))))
+                "0j4p91xx1scg3jmvq6km7bwfjz5ihafk76yf1byb6aqyw50h3bm3"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config qttools-5))
@@ -1418,7 +1467,7 @@ ASpell and HUNSPELL.")
 (define-public threadweaver
   (package
     (name "threadweaver")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1427,7 +1476,7 @@ ASpell and HUNSPELL.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0ljjnbwmc2zz4q0q1njqny43cj6xdf976vrvijcsqdsril5wzdbq"))))
+                "1pwinpz5kscx64kc7dn4qf76m64kxzp92zjk8j2a2s1mx0s0vk2s"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1448,7 +1497,7 @@ uses a job-based interface to queue tasks and execute them in an efficient way."
 (define-public kactivities
   (package
     (name "kactivities")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1457,7 +1506,7 @@ uses a job-based interface to queue tasks and execute them in an efficient way."
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0g16k3v6i20rc6h0js4pk00d6yg236bs0kxj88q21d5c934hbksk"))))
+                "0n7r88y1b8mph5al2xh8fbw5ckdzdmdzjipf205y20ib35bskd9i"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1493,7 +1542,7 @@ with other frameworks.")
 (define-public kauth
   (package
     (name "kauth")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1502,7 +1551,7 @@ with other frameworks.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1hi36504bbr0266wl08kqiq61xysl3dw3kpgjfbgx169m0m3gmx9"))))
+                "0nzdvx2mibpq1cgzpll9ffjr46vch1qvriaywyqih0iybx6mx5z6"))))
     (build-system cmake-build-system)
     (native-inputs
      (list dbus extra-cmake-modules qttools-5))
@@ -1537,7 +1586,7 @@ utilities.")
 (define-public kcompletion
   (package
     (name "kcompletion")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1546,7 +1595,7 @@ utilities.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1jmrd2mfz27qfn6dq1mk6bcqlagmifbf9vnayi1mkqa9jsj4dwdj"))))
+                "191vid00zskvhl6dgj6yz9iyvwdcmg35l5gq68ggjr17cj59acsf"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -1562,16 +1611,18 @@ integrated it into your application's other widgets.")
 (define-public kcontacts
   (package
     (name "kcontacts")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
                     "mirror://kde/stable/frameworks/"
                     (version-major+minor version) "/"
                     name "-" version ".tar.xz"))
+              (patches
+               (search-patches "kcontacts-incorrect-country-name.patch"))
               (sha256
                (base32
-                "075mw7clqf7qycngly21q3m0js3g8pcgqc2x3alp28f4zq3c8m21"))))
+                "0g3lg1i9rg7hjw7xjx9228sy54dy35lgwghcjds5cawszl5yi106"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules xorg-server)) ; for the tests
@@ -1593,14 +1644,8 @@ integrated it into your application's other widgets.")
                (setenv "HOME" (getcwd))
                (system "Xvfb :1 -screen 0 640x480x24 &")
                (setenv "DISPLAY" ":1")
-               ;; testrounddrip fail inconsistently.
-               ;; addresstest produces wrong value:
-               ;;Actual   (address.formattedAddress(QStringLiteral("Jim Knopf"))):
-               ;;"Jim Knopf\nLummerlandstr. 1\n12345 Lummerstadt\n\nGERMANY"
-               ;;Expected (result)                                               :
-               ;;"Jim Knopf\nLummerlandstr. 1\n12345 Lummerstadt\n\nGERMANIA"
                (invoke "ctest" "-E"
-			   "(kcontacts-addresstest|kcontacts-emailtest|kcontacts-phonenumbertest|kcontacts-soundtest|kcontacts-secrecytest|kcontacts-geotest|kcontacts-keytest|kcontacts-testroundtrip|kcontacts-impptest|kcontacts-birthdaytest|kcontacts-addresseetest)")))))))
+                "(kcontacts-birthdaytest|kcontacts-testroundtrip|kcontacts-addresstest)")))))))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "API for contacts/address book data following the vCard standard")
     (description "This library provides a vCard data model, vCard
@@ -1612,7 +1657,7 @@ localized country name to ISO 3166-1 alpha 2 code mapping and vice verca.
 (define-public kcrash
   (package
     (name "kcrash")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1621,7 +1666,7 @@ localized country name to ISO 3166-1 alpha 2 code mapping and vice verca.
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "05sw3lh4lw5jgl7gvxvpyl6nims9j4b1hjsn365fa2p48qmsx6v5"))))
+                "03ba3x9jgp15dxgwbjnv5s98f5di2z4ncp4hiv1qkyiibqqfx6kf"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1636,7 +1681,7 @@ application crashes.")
 (define-public kdoctools
   (package
     (name "kdoctools")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1645,7 +1690,7 @@ application crashes.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "04nk87dbmnf9840401s40mxlsfh9is1l1mqky9xi5mcghbp0308b"))))
+                "0ygpjasdynsmb3c8rdwnc5jminl5f34cmqnihsig831xsq8z6chs"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1691,7 +1736,7 @@ from DocBook files.")
 (define-public kfilemetadata
   (package
     (name "kfilemetadata")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1700,7 +1745,7 @@ from DocBook files.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0sh3malq6007fp5m4hica20ha8z5abqzq5ifcmrpm8zqmm5aa2bq"))))
+                "1nsvslhs2kiff3r5ji8z931lh6srvjzzvwnv9cs0j74sr46c6rkn"))))
     (build-system cmake-build-system)
     (arguments
      `(#:phases
@@ -1715,9 +1760,11 @@ from DocBook files.")
     (native-inputs (list extra-cmake-modules pkg-config))
     (inputs
      (list attr
-           ;; TODO: EPub http://sourceforge.net/projects/ebook-tools
+           ebook-tools
            karchive
+           kconfig
            kcoreaddons
+           kdegraphics-mobipocket
            ki18n
            qtmultimedia-5
            qtbase-5
@@ -1739,7 +1786,7 @@ by applications to write metadata.")
 (define-public kimageformats
   (package
     (name "kimageformats")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1748,7 +1795,7 @@ by applications to write metadata.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0dbl2varirp5f1bd8173jlhmkc3ql16yg0d6w04nc56hy973bkm5"))))
+                "0v4jr1lh2qjk453q8mpz94cd98k4kmjrykn8kxrd7zvrkaa4snfy"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config))
@@ -1791,7 +1838,7 @@ formats.")
 (define-public kjobwidgets
   (package
     (name "kjobwidgets")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1800,7 +1847,7 @@ formats.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1w1h9vnlq1j72812558cl5dlq7f80nnh5i30qmkpbvv49xhhq2dl"))))
+                "0f87n5d3h2f9y1z2imfd0jj9108wbcxg7dg4k1c53zar2lrfx4wc"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -1815,7 +1862,7 @@ asynchronous jobs.")
 (define-public knotifications
   (package
     (name "knotifications")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1824,10 +1871,10 @@ asynchronous jobs.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "11fbqylchzvm0pfw8bvy03px5zcg4jbch39vzcvnl6si7vikm4qj"))))
+                "10whr3wjldaxdvbj6i250rqgsy2m1n606ja1yka571f1fz7laqcd"))))
     (build-system cmake-build-system)
     (native-inputs
-     (list extra-cmake-modules dbus qttools-5))
+     (list extra-cmake-modules dbus pkg-config qttools-5))
     (inputs
      (list kcodecs
            kconfig
@@ -1858,7 +1905,7 @@ covers feedback and persistent events.")
 (define-public kpackage
   (package
     (name "kpackage")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1867,7 +1914,7 @@ covers feedback and persistent events.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0gsxizpqa47apbvchga3f0w86v4jh8z1vyf0kifipz17fay4ws8d"))))
+                "1234jq9qqhq2z5afkkniz6w5s1ab9r4x9wamq3c9y08nzjq634py"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1914,7 +1961,7 @@ were traditional plugins.")
 (define-public kpty
   (package
     (name "kpty")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1923,7 +1970,7 @@ were traditional plugins.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "15swvv6qhvc654wyvxzbjbnzrd2vwn0mr4lby1x6x5f4c9br0cip"))))
+                "0arxbdxldwnrcg5x1vpvkwdd4hayrpqvn08jz6r7zb4s9h1582ww"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1949,7 +1996,7 @@ and communicating with them using a pty.")
 (define-public kunitconversion
   (package
     (name "kunitconversion")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1958,7 +2005,7 @@ and communicating with them using a pty.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1qls3319gwn1nzaq04wrqjhbchk0s0pfx97m4za63yzvapvym73g"))))
+                "0lhyg1d1k25kqk94lzy8mb06p4c17limmcrzirnsnxjvhjrc6r05"))))
     (build-system cmake-build-system)
     (arguments `(#:tests? #f)) ;; Requires network.
     (native-inputs
@@ -1976,7 +2023,7 @@ gallons).")
 (define-public syndication
   (package
     (name "syndication")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -1985,7 +2032,7 @@ gallons).")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1q60dznlkbncqqgjnp3lq3x0f6r7wvz141ajkymmxlgfq3wdpcd4"))))
+                "04py880hxkvidydsqcyjbkq0wv9cp42d7svkdgf74fmzfyfrmrax"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -2008,7 +2055,7 @@ between feed formats.")
 (define-public baloo
   (package
     (name "baloo")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2017,7 +2064,7 @@ between feed formats.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1icpxmmxhvgdr6zxpz0wybc82nyy595cmr09067i82kh7v5dj66l"))))
+                "0x515lnvrzlnsv5i924q17mzi88k00krj90myad17s0g7p5pi1rw"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kcoreaddons kfilemetadata))
@@ -2070,7 +2117,7 @@ maintaining an index of the contents of your files.")
 (define-public kactivities-stats
   (package
     (name "kactivities-stats")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2079,7 +2126,7 @@ maintaining an index of the contents of your files.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0lfanv55b7zx5s0a7gh4r41w9yb641j1zjjcvdjfrj7pdh52576s"))))
+                "0zvw3km1wf91wl9xbjvawjia0847kbs3js4nbf3d0z87l5h6rbx8"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -2096,7 +2143,7 @@ by which applications, and what documents have been linked to which activity.")
 (define-public kbookmarks
   (package
     (name "kbookmarks")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2105,7 +2152,7 @@ by which applications, and what documents have been linked to which activity.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "131yng8wmxrnf3x1i6gg60q3rrya19yk4jnzi5ylafvaw7q2r8b4"))))
+                "1rpjqz2xnpb2wp2k3pjdclbkb0p96y48x6h8l056nr93alxyrqvi"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kwidgetsaddons))
@@ -2137,7 +2184,7 @@ using the XBEL format.")
 (define-public kcmutils
   (package
     (name "kcmutils")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2146,7 +2193,7 @@ using the XBEL format.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0vff93kja9dq8rf1aapxpfgjxsinm75f5nydxqcihskp8girz0c8"))))
+                "0jqkg4i16jnxricrhi1cbvv7gjjj7ry3z36mzh11h48ml7rl05qx"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kconfigwidgets kservice))
@@ -2192,7 +2239,7 @@ KCModules can be created with the KConfigWidgets framework.")
 (define-public kconfigwidgets
   (package
     (name "kconfigwidgets")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2201,7 +2248,7 @@ KCModules can be created with the KConfigWidgets framework.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "045j6gkp5sf1lc12zwlkr1dz0fd89yrg5b31j4ybk3dyc8jz90hl"))))
+                "05bwldqc5k6dlzsxjby5565sch6i0mh7jg5cbyjz24xb1fpj0d7b"))))
     (build-system qt-build-system)
     (propagated-inputs
      (list kauth kcodecs kconfig kwidgetsaddons))
@@ -2224,7 +2271,7 @@ KCModules can be created with the KConfigWidgets framework.")
                (("^\\s*(QDirIterator it\\(.*, QDirIterator::Subdirectories)(\\);)" _ a b)
                 (string-append a " | QDirIterator::FollowSymlinks" b)))
              (substitute* "CMakeLists.txt"
-               (("5\\.90\\.0") "5.96.0"))))
+               (("5\\.90\\.0") "5.98.0"))))
          (replace 'check
            (lambda* (#:key tests? #:allow-other-keys)
              (when tests?
@@ -2240,7 +2287,7 @@ their settings.")
 (define-public kdeclarative
   (package
     (name "kdeclarative")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2249,7 +2296,7 @@ their settings.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1x4r231g0l5im4ala21m5fz5q6nixbx0z6lfia5zjinzlp7x5534"))))
+                "0y5scmcnzhwvyb7x6fdb59xgdhghw8v9i3r05gx1x7g1gfsw0wh6"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kconfig kpackage qtdeclarative-5))
@@ -2303,7 +2350,7 @@ that offer bindings to some of the Frameworks.")
 (define-public kded
   (package
     (name "kded")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2312,7 +2359,7 @@ that offer bindings to some of the Frameworks.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0x40yvcx2gjb4pngyk2vfrn3z7dbyvksbj1h3ck04fyyma8z3gb3"))))
+                "1k8yxdnihfvvdjmw7lmd62vi5k1hpvjdcwd7njqxz6178iq7dd75"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools))
@@ -2335,7 +2382,7 @@ started on demand.")
 (define-public kdesignerplugin
   (package
     (name "kdesignerplugin")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2344,7 +2391,7 @@ started on demand.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0cddad1rdi06l28iiwizfds78dplbvv7j40vphww0ix7cmsh3rh9"))))
+                "17b0javl6k5zcmx04aqzmh3qdgwvzhf62x603m4pg6xbl3zns67g"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools qttools-5))
@@ -2364,7 +2411,7 @@ ini-style description files.")
 (define-public kdesu
   (package
     (name "kdesu")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2373,7 +2420,7 @@ ini-style description files.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1wjjjwpfjr7sx10x0236zqjx3jrw6mz60724s5qg269dwfbpahvj"))))
+                "15fbb7zifk4lhnlwvqhs9svzb80qwms03zbrjfnsc1n1wyyfk7v2"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kpty))
@@ -2391,7 +2438,7 @@ with su and ssh respectively.")
 (define-public kdewebkit
   (package
     (name "kdewebkit")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2400,7 +2447,7 @@ with su and ssh respectively.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0l8nnar4s84igxih5w0fhwd9nvccp7zm53jy2gk6lfbj6gqarfbf"))))
+                "03bwwgzh1xfj4w7q2cvr7712yrjgf9qhqkqgzypcdb49gpvaq164"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -2423,7 +2470,7 @@ engine WebKit via QtWebKit.")
 (define-public kemoticons
   (package
     (name "kemoticons")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2432,7 +2479,7 @@ engine WebKit via QtWebKit.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "03b5axwvd6ayw1kbl1jv6h04cihp1y1pa835gs3m1qx2ivgj7f75"))))
+                "0f3d0jmpnqkrjn95sbvjzda923rfdgrlxd4k58pmzd0bblxkcxh2"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kservice))
@@ -2459,7 +2506,7 @@ emoticons coming from different providers.")
 (define-public kglobalaccel
   (package
     (name "kglobalaccel")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2468,7 +2515,7 @@ emoticons coming from different providers.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1sx4fmy8xy22im0i3dw0xdmxrgw2jhnk2wsfy2xw74dsj3adg2iq"))))
+                "1vr6k7lpxsxa6in60ld2wcdqfpaan5xgbmwm3xyr584x6pv737cl"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config qttools-5))
@@ -2492,7 +2539,7 @@ window does not need focus for them to be activated.")
 (define-public kiconthemes
   (package
     (name "kiconthemes")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2501,7 +2548,7 @@ window does not need focus for them to be activated.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0w9m956xfpfxp7a63a5v2y10lb9zp2gqfjyfvq3ksxfl961g4hsg"))))
+                "1qmld8xgabmwx2dh5395pll0a0jgirxhlbqv6aph76jg4lvynkqx"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5 shared-mime-info))
@@ -2516,18 +2563,20 @@ window does not need focus for them to be activated.")
            kitemviews
            kwidgetsaddons
            qtbase-5
+           qtdeclarative-5
            qtsvg-5))
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (add-before 'check 'check-setup
-           (lambda* (#:key inputs #:allow-other-keys)
-             (setenv "XDG_DATA_DIRS"
-                     (string-append (assoc-ref inputs "shared-mime-info")
-                                    "/share"))
-             (setenv "HOME" (getcwd))
-             ;; make Qt render "offscreen", required for tests
-             (setenv "QT_QPA_PLATFORM" "offscreen"))))))
+     (list #:phases
+           #~(modify-phases %standard-phases
+               (add-before 'check 'check-setup
+                 (lambda* (#:key inputs #:allow-other-keys)
+                   (setenv "XDG_DATA_DIRS"
+                           (string-append #$(this-package-native-input
+                                             "shared-mime-info")
+                                          "/share"))
+                   (setenv "HOME" (getcwd))
+                   ;; make Qt render "offscreen", required for tests
+                   (setenv "QT_QPA_PLATFORM" "offscreen"))))))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "Icon GUI utilities")
     (description "This library contains classes to improve the handling of icons
@@ -2537,7 +2586,7 @@ in applications using the KDE Frameworks.")
 (define-public kinit
   (package
     (name "kinit")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2546,21 +2595,23 @@ in applications using the KDE Frameworks.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1y7x80icm2jv9c8917481w1hs1vm2rvvvnc9drw4q7vrjzfx73dq"))
+                "04654hz3yipnlhy5gz3bkh988fcfl1lv7608k4xa5qnbsxaqh141"))
               ;; Use the store paths for other packages and dynamically loaded
               ;; libs
               (patches (search-patches "kinit-kdeinit-extra_libs.patch"))))
     (build-system cmake-build-system)
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (add-after 'unpack 'patch-paths
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             ;; Set patched-in values:
-             (substitute* "src/kdeinit/kinit.cpp"
-               (("GUIX_PKGS_KF5_KIO") (assoc-ref inputs "kio"))
-               (("GUIX_PKGS_KF5_PARTS") (assoc-ref inputs "kparts"))
-               (("GUIX_PKGS_KF5_PLASMA") (assoc-ref inputs "plasma-framework"))))))))
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'patch-paths
+            (lambda* (#:key inputs outputs #:allow-other-keys)
+              ;; Set patched-in values:
+              (substitute* "src/kdeinit/kinit.cpp"
+                (("GUIX_PKGS_KF5_KIO") #$(this-package-input "kio"))
+                (("GUIX_PKGS_KF5_PARTS") #$(this-package-input "kparts"))
+                (("GUIX_PKGS_KF5_PLASMA")
+                 #$(this-package-input "plasma-framework"))))))))
     (native-search-paths
      (list (search-path-specification
             (variable "KDEINIT5_LIBRARY_PATH")
@@ -2604,7 +2655,7 @@ consumption.")
 (define-public kio
   (package
     (name "kio")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2613,11 +2664,12 @@ consumption.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0xmvgq7cp1kkicmngxjj4cmijaah91jmfqdzzxziphq1rl23k64m"))
+                "0z1ikpa3an3qmd26h2v48kxxw1jph21i12x4nawvc4x1dp4vkm1d"))
               (patches (search-patches "kio-search-smbd-on-PATH.patch"))))
     (build-system cmake-build-system)
     (propagated-inputs
-     (list kbookmarks
+     (list acl
+           kbookmarks
            kconfig
            kcompletion
            kcoreaddons
@@ -2629,14 +2681,14 @@ consumption.")
            solid))
     (native-inputs
      (list extra-cmake-modules dbus kdoctools qttools-5))
-    (inputs (list ;; TODO:  LibACL , <ftp://oss.sgi.com/projects/xfs/cmd_tars>
-                  mit-krb5
+    (inputs (list mit-krb5
                   karchive
                   kauth
                   kcodecs
                   kconfigwidgets
                   kcrash
                   kdbusaddons
+                  kded
                   kguiaddons
                   kiconthemes
                   ki18n
@@ -2647,14 +2699,15 @@ consumption.")
                   libxml2
                   libxslt
                   qtbase-5
+                  qtdeclarative-5
                   qtscript
                   qtx11extras
                   sonnet
                   `(,util-linux "lib") ; libmount
                   zlib))
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
+     (list #:phases
+       #~(modify-phases %standard-phases
          (add-after 'unpack 'patch
            (lambda _
              ;; Better error message (taken from NixOS)
@@ -2669,35 +2722,30 @@ consumption.")
                (setenv "QT_QPA_PLATFORM" "offscreen")
                (setenv "DBUS_FATAL_WARNINGS" "0")
                (invoke "dbus-launch" "ctest"
-                       "-E" ; FIXME: 21/67 tests fail.
+                       "-E" ; FIXME: 17/69 tests fail.
                        (string-append "(kiocore-jobtest"
-                                      "|fileitemtest"
                                       "|kiocore-kmountpointtest"
+                                      "|kiocore-kfileitemtest"
                                       "|kiocore-ktcpsockettest"
                                       "|kiocore-mimetypefinderjobtest"
                                       "|kiocore-krecentdocumenttest"
                                       "|kiocore-http_jobtest"
                                       "|kiogui-openurljobtest"
-                                      "|kiocore-threadtest"
                                       "|applicationlauncherjob_forkingtest"
                                       "|applicationlauncherjob_scopetest"
                                       "|applicationlauncherjob_servicetest"
                                       "|commandlauncherjob_forkingtest"
                                       "|commandlauncherjob_scopetest"
                                       "|commandlauncherjob_servicetest"
-                                      "|kiowidgets-kdirlistertest"
                                       "|kiowidgets-kdirmodeltest"
-                                      "|kiowidgets-kfileitemactionstest"
                                       "|kiowidgets-kurifiltertest-colon-separator"
-                                      "|kiowidgets-kurifiltertest-space-separator"
-                                      "|kiofilewidgets-knewfilemenutest)")))))
+                                      "|kiowidgets-kurifiltertest-space-separator)")))))
          (add-after 'install 'add-symlinks
            ;; Some package(s) (e.g. bluedevil) refer to these service types by
            ;; the wrong name.  I would prefer to patch those packages, but I
            ;; cannot find the files!
            (lambda* (#:key outputs #:allow-other-keys)
-             (let ((kst5 (string-append (assoc-ref outputs "out")
-                                        "/share/kservicetypes5/")))
+             (let ((kst5 (string-append #$output "/share/kservicetypes5/")))
                (symlink (string-append kst5 "kfileitemactionplugin.desktop")
                         (string-append kst5 "kfileitemaction-plugin.desktop"))))))))
     (home-page "https://community.kde.org/Frameworks")
@@ -2714,7 +2762,7 @@ KIO enabled infrastructure.")
 (define-public knewstuff
   (package
     (name "knewstuff")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2723,7 +2771,7 @@ KIO enabled infrastructure.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0kls40wlqkqirfjhf8kn83saxwahlh4rkm7iypqd81h93gi81fgc"))))
+                "09mxzpv0l1i5ml963gdnji8rskmi8b2f0hp4rn6ibkcj00z48fgy"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list attica kservice kxmlgui))
@@ -2768,7 +2816,7 @@ specification.")
 (define-public knotifyconfig
   (package
     (name "knotifyconfig")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2777,7 +2825,7 @@ specification.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "09bcw47zp6rsnk7f83gkmlpylg428a7phn7bbi9mpkdpzc6zvfd2"))))
+                "1qlmgr5rifygp8zk8qfjwm6k72kfyj8x6hvqwy2a59lfi3wgbm07"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -2810,7 +2858,7 @@ notifications which can be embedded in your application.")
 (define-public kparts
   (package
     (name "kparts")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2819,7 +2867,7 @@ notifications which can be embedded in your application.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0b68kyi7l3ndw798sll2hrzf6qq6w875n48sc11q6882xilzinh2"))))
+                "01gcnywbzrgwlk4cws2rr139r95r201yfal1af3jkd7g2x499vgr"))))
     (build-system qt-build-system)
     (arguments
      '(#:phases (modify-phases %standard-phases
@@ -2860,7 +2908,7 @@ widgets with a user-interface defined in terms of actions.")
 (define-public kpeople
   (package
     (name "kpeople")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2869,7 +2917,7 @@ widgets with a user-interface defined in terms of actions.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0q3c0ghxa9km5xcq6h0cwa7swfd18h491jpfafy4qgq3nwp0115b"))))
+                "0wxy8pxkbfqbb4i9v3q912shzck56bk6xra3blhwva82qm9rps0f"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -2896,7 +2944,7 @@ to easily extend the contacts collection.")
 (define-public krunner
   (package
     (name "krunner")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2905,7 +2953,7 @@ to easily extend the contacts collection.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0wd2nmhw9mb09mm88cnkmirwgxdnvkrkyjvaiqh9k74xqsggnplk"))))
+                "0kch839xw09h1lddqgdcfwniq6rza5wdyyzcx99hcasn7l60nhsj"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list plasma-framework))
@@ -2914,7 +2962,8 @@ to easily extend the contacts collection.")
            ;; For tests.
            dbus))
     (inputs
-     (list kauth
+     (list kactivities
+           kauth
            kbookmarks
            kcodecs
            kcompletion
@@ -2935,26 +2984,24 @@ to easily extend the contacts collection.")
            solid
            threadweaver))
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (add-after 'unpack 'fix-paths-for-test
-           ;; This test tries to access paths like /home, /usr/bin and /bin/ls
-           ;; which don't exist in the build-container. Change to existing paths.
-           (lambda* (#:key inputs #:allow-other-keys)
-             (substitute* "autotests/runnercontexttest.cpp"
-               (("/home\"") "/tmp\"") ;; single path-part
-               (("//usr/bin\"") (string-append (getcwd) "\"")) ;; multiple path-parts
-               (("/bin/ls")
-                (search-input-file inputs "/bin/ls")))))
-         (replace 'check
-           (lambda* (#:key tests? #:allow-other-keys)
-             (when tests?
-               (setenv "HOME" (getcwd))
-               (setenv "QT_QPA_PLATFORM" "offscreen")
-               (invoke "dbus-launch" "ctest"
-                       "-E" ;; Some tests fail
-                       "(runnercontexttest|dbusrunnertest|\
-runnermanagersinglerunnermodetest|runnermanagertest)")))))))
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'fix-paths-for-test
+            ;; This test tries to access paths like /home, /usr/bin and /bin/ls
+            ;; which don't exist in the build-container. Change to existing paths.
+            (lambda* (#:key inputs #:allow-other-keys)
+              (substitute* "autotests/runnercontexttest.cpp"
+                (("/home\"") "/tmp\"") ;; single path-part
+                (("//usr/bin\"") (string-append (getcwd) "\"")) ;; multiple path-parts
+                (("/bin/ls")
+                 (search-input-file inputs "/bin/ls")))))
+          (replace 'check
+            (lambda* (#:key tests? #:allow-other-keys)
+              (when tests?
+                (setenv "HOME" (getcwd))
+                (setenv "QT_QPA_PLATFORM" "offscreen")
+                (invoke "dbus-launch" "ctest")))))))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "Framework for Plasma runners")
     (description "The Plasma workspace provides an application called KRunner
@@ -2966,7 +3013,7 @@ typed.")
 (define-public kservice
   (package
     (name "kservice")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -2975,7 +3022,7 @@ typed.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1zg3a35my8ba5ikmlg9s3wc9r0s5a2x0rggiiv9znhfi3snvi6gd"))))
+                "0lgwpcdkkbxwq84zp5aymrdwy0iacqxz5ckc89pymcm0bacyhl31"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kconfig kcoreaddons kdoctools))
@@ -3017,7 +3064,7 @@ types or handled by application specific code.")
 (define-public ktexteditor
   (package
     (name "ktexteditor")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -3026,7 +3073,7 @@ types or handled by application specific code.")
                     "ktexteditor-" version ".tar.xz"))
               (sha256
                (base32
-                "071jx26ycyk31bh167cq5fwx8xkr4ldjg8zlhn9dh7wa3rjpp183"))))
+                "1pazi9rz4v95g31s7d26yla8rcb0cgd08mlmdcasywsaxc8nn7vw"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kparts
@@ -3034,7 +3081,7 @@ types or handled by application specific code.")
     (native-inputs
      (list extra-cmake-modules pkg-config))
     (inputs
-     (list ;; TODO: editor-config
+     (list editorconfig-core-c
            karchive
            kauth
            kbookmarks
@@ -3049,6 +3096,7 @@ types or handled by application specific code.")
            kitemviews
            ki18n
            kjobwidgets
+           kparts
            kservice
            ktextwidgets
            kwidgetsaddons
@@ -3062,23 +3110,23 @@ types or handled by application specific code.")
            solid
            sonnet))
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
+     (list #:phases
+       #~(modify-phases %standard-phases
          (add-after 'unpack 'setup
            (lambda* (#:key inputs #:allow-other-keys)
              (setenv "XDG_DATA_DIRS" ; FIXME build phase doesn't find parts.desktop
-                     (string-append (assoc-ref inputs "kparts") "/share"))))
+                     (string-append #$(this-package-input "kparts") "/share"))))
          (replace 'check
            (lambda* (#:key tests? #:allow-other-keys)
              (when tests? ;; Maybe locale issues with tests?
                (setenv "QT_QPA_PLATFORM" "offscreen")
-               (invoke "ctest" "-E" "(completion_test|kateview_test|movingrange_test)"))))
+               (invoke "ctest" "-E" "(kateview_test|movingrange_test)"))))
          (add-after 'install 'add-symlinks
            ;; Some package(s) (e.g. plasma-sdk) refer to these service types
            ;; by the wrong name.  I would prefer to patch those packages, but
            ;; I cannot find the files!
            (lambda* (#:key outputs #:allow-other-keys)
-             (let ((kst5 (string-append (assoc-ref outputs "out")
+             (let ((kst5 (string-append #$output
                                         "/share/kservicetypes5/")))
                (symlink (string-append kst5 "ktexteditorplugin.desktop")
                         (string-append kst5 "ktexteditor-plugin.desktop"))))))))
@@ -3093,7 +3141,7 @@ library.")
 (define-public ktextwidgets
   (package
     (name "ktextwidgets")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -3102,7 +3150,7 @@ library.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1vab4qmqq9268bwzx6xia2bcz8rdmiwlgjkbkk8nci2pnmhjrzpj"))))
+                "14ivmpng7x9rsk3x6kyd86jabzqxgjcdrma1im44wacnvisi4llk"))))
     (build-system qt-build-system)
     (propagated-inputs
      (list ki18n sonnet))
@@ -3131,7 +3179,7 @@ It supports rich text as well as plain text.")
 (define-public kwallet
   (package
     (name "kwallet")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -3140,8 +3188,16 @@ It supports rich text as well as plain text.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0rj610c7i66fbv1x0i0sfn9mac8fkqir4vwgaq1ad5i9ca36h1jq"))))
+                "0kwxkxlk0xlxkjgpjpb40xfl2l9hnhpymb4lxw4zwlxjn81r6sab"))))
     (build-system cmake-build-system)
+    (arguments
+     (list #:phases
+       #~(modify-phases %standard-phases
+         (replace 'check
+           (lambda* (#:key tests? #:allow-other-keys)
+             (when tests? ;; Seems to require network.
+               (invoke "ctest" "-E"
+                       "(fdo_secrets_test)")))))))
     (native-inputs
      (list extra-cmake-modules kdoctools))
     (inputs
@@ -3162,6 +3218,7 @@ It supports rich text as well as plain text.")
            libgcrypt
            phonon
            qgpgme
+           qca
            qtbase-5))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "Safe desktop-wide storage for passwords")
@@ -3173,7 +3230,7 @@ the passwords on KDE work spaces.")
 (define-public kxmlgui
   (package
     (name "kxmlgui")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -3182,12 +3239,12 @@ the passwords on KDE work spaces.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1hiz2fgwpc4mgh2zzir0qi18pjsc3052lf888rc1pgql90faxb1k"))))
+                "08n5l3zgkh0fxaqwrfx5mk4j5wq9ylkpxd37751qcivpag7l0x45"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kconfig kconfigwidgets))
     (native-inputs
-     (list extra-cmake-modules qttools-5))
+     (list extra-cmake-modules qttools-5 xorg-server-for-tests))
     (inputs
      (list attica
            kauth
@@ -3204,14 +3261,15 @@ the passwords on KDE work spaces.")
            qtbase-5
            sonnet))
     (arguments
-     `(#:tests? #f ; FIXME: 1/5 tests fail.
-       #:phases
-       (modify-phases %standard-phases
-         (add-before 'check 'check-setup
-           (lambda _
-             (setenv "HOME" (getcwd))
-             ;; make Qt render "offscreen", required for tests
-             (setenv "QT_QPA_PLATFORM" "offscreen"))))))
+     (list #:phases
+       #~(modify-phases %standard-phases
+         (replace 'check
+           (lambda* (#:key tests? #:allow-other-keys)
+             (when tests?
+               (setenv "HOME" (getcwd))
+               (setenv "QT_QPA_PLATFORM" "offscreen") ;; These tests fail
+               (invoke "ctest" "-E"
+			   "(ktoolbar_unittest|kxmlgui_unittest)")))))))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "Framework for managing menu and toolbar actions")
     (description "KXMLGUI provides a framework for managing menu and toolbar
@@ -3224,7 +3282,7 @@ descriptions for integrating actions from plugins.")
 (define-public kxmlrpcclient
   (package
     (name "kxmlrpcclient")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -3233,7 +3291,7 @@ descriptions for integrating actions from plugins.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1jrmrzcvnnw7q7pxgfpcz8608jmxqxf89habmgwv71b8kjz3vgaw"))))
+                "09apfrkgvvzv8zwxyjbi5qb145a9awirk02nx474bshgypfqslpb"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kio))
@@ -3267,7 +3325,7 @@ setUrl, setUserAgent and call.")
 (define-public plasma-framework
   (package
     (name "plasma-framework")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -3276,7 +3334,7 @@ setUrl, setUserAgent and call.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "14myvv70pixygb20c136sk7prv5f5dca53fgc74dk6c28hwyldh2"))))
+                "1bmwvk0pj0bnb8qhcl0bz82r63nls6h7lzzmkfkdwcwmjifmiqg4"))))
     (build-system cmake-build-system)
     (propagated-inputs
      (list kpackage kservice))
@@ -3318,11 +3376,6 @@ setUrl, setUserAgent and call.")
     (arguments
      `(#:phases
        (modify-phases %standard-phases
-	   ;; Fix based on https://invent.kde.org/frameworks/plasma-framework/-/issues/13
-	     (add-after 'unpack 'apply-fix
-		  (lambda* _
-		   (substitute* "src/scriptengines/qml/CMakeLists.txt"
-		   (("KF5::ConfigQml") ""))))
          (replace 'check
            (lambda* (#:key tests? #:allow-other-keys)
              (when tests?
@@ -3342,7 +3395,7 @@ script engines.")
 (define-public purpose
   (package
     (name "purpose")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -3351,7 +3404,7 @@ script engines.")
                     name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0gji3dsccbii1gm83dpwry02cqmjrimhj8gnkb6nzvzrnq5xfh3r"))))
+                "0g9ykhsn9dl3y3qp4wm3r7bkdhpl9mcbg671wa26qx3ba8a2jynr"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -3387,11 +3440,11 @@ need.")
     (source (origin
               (inherit (package-source kdbusaddons))
               (patches '())))
-    (inputs (alist-delete "kinit" (package-inputs kdbusaddons)))
+    (inputs (modify-inputs (package-inputs kdbusaddons) (delete "kinit")))
     (arguments
      (substitute-keyword-arguments (package-arguments kdbusaddons)
        ((#:phases phases)
-        `(modify-phases ,phases
+        #~(modify-phases #$phases
            (delete 'patch-source)))))))
 
 (define kinit-bootstrap
@@ -3408,7 +3461,7 @@ need.")
 (define-public kde-frameworkintegration
   (package
     (name "kde-frameworkintegration")
-    (version "5.96.0")
+    (version "5.98.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -3417,7 +3470,7 @@ need.")
                     "frameworkintegration-" version ".tar.xz"))
               (sha256
                (base32
-                "19piq6h51qh64nbkqnpy6jg91vbl67vg2sh4hlwzsb2lcrmwxgk9"))))
+                "1mrangjj8lhm4njpkhqna2zwnidkd9crs23gj6kdlwzmiknypi6q"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config))
@@ -3462,7 +3515,7 @@ workspace.")
 (define-public kdelibs4support
   (package
     (name "kdelibs4support")
-    (version "5.96.0")
+    (version "5.98.0")
     (source
      (origin
        (method url-fetch)
@@ -3471,7 +3524,7 @@ workspace.")
              (version-major+minor version) "/portingAids/"
              name "-" version ".tar.xz"))
        (sha256
-        (base32 "18f99g1g1z1mrkgq3l8kgxjxi60a632p0sg8d46r67b9n008w9m7"))))
+        (base32 "0hyyrxic1rkw2jrr92rnmbk6bqkfrcnpc917vs7xyansk9799b8f"))))
     (build-system cmake-build-system)
     (native-inputs
      (list dbus
@@ -3556,9 +3609,8 @@ workspace.")
              (with-output-to-file "autotests/BLACKLIST"
                (lambda _
                  (display "[testSmb]\n*\n")))
-             ;; kuniqueapptest hangs. FIXME: Make this test pass.
              (invoke "dbus-launch" "ctest"
-                     "-E" "kstandarddirstest|kuniqueapptest"))))))
+                     "-E" "kstandarddirstest"))))))
     (home-page "https://community.kde.org/Frameworks")
     (synopsis "KDE Frameworks 5 porting aid from KDELibs4")
     (description "This framework provides code and utilities to ease the
@@ -3579,7 +3631,7 @@ http://community.kde.org/Frameworks/Porting_Notes should help with this.")
 (define-public khtml
   (package
     (name "khtml")
-    (version "5.96.0")
+    (version "5.98.0")
     (source
      (origin
        (method url-fetch)
@@ -3588,7 +3640,7 @@ http://community.kde.org/Frameworks/Porting_Notes should help with this.")
              (version-major+minor version) "/portingAids/"
              name "-" version ".tar.xz"))
        (sha256
-        (base32 "0lc933z4568962xj7grzy44aj97h76s5vvv1cnj351dzwr5qahpx"))))
+        (base32 "0bflwrp6i2w6a3fq2m2df655495rpnsmqcm7w1f1dzfndc6yd9i5"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules perl))
@@ -3629,7 +3681,7 @@ technology and using KJS for JavaScript support.")
 (define-public kjs
   (package
     (name "kjs")
-    (version "5.96.0")
+    (version "5.98.0")
     (source
      (origin
        (method url-fetch)
@@ -3638,7 +3690,7 @@ technology and using KJS for JavaScript support.")
              (version-major+minor version) "/portingAids/"
              name "-" version ".tar.xz"))
        (sha256
-        (base32 "0jhfjjpv5hzbib3p30ngn6ic023fnrvnr8jrbjdzyacjywj69vvp"))))
+        (base32 "03is1a5b1sfh1nd011lchgir9nrywvax06ilg9y7z0vsn0ick7ik"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools perl pkg-config))
@@ -3658,7 +3710,7 @@ support.")
 (define-public kjsembed
   (package
     (name "kjsembed")
-    (version "5.96.0")
+    (version "5.98.0")
     (source
      (origin
        (method url-fetch)
@@ -3667,7 +3719,7 @@ support.")
              (version-major+minor version) "/portingAids/"
              name "-" version ".tar.xz"))
        (sha256
-        (base32 "1z8h0n4v1qgs2lsxflrzhdfb91jna3y2dxal1qz7i3szjvrf63h0"))))
+        (base32 "0zb4vr0hp73lzc1gfnpq1grwmlpdvnp8awf3ydx4vqjh9n6jbaf2"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools qttools-5))
@@ -3682,7 +3734,7 @@ QObjects, so you can script your applications.")
 (define-public kmediaplayer
   (package
     (name "kmediaplayer")
-    (version "5.96.0")
+    (version "5.98.0")
     (source
      (origin
        (method url-fetch)
@@ -3691,7 +3743,7 @@ QObjects, so you can script your applications.")
              (version-major+minor version) "/portingAids/"
              name "-" version ".tar.xz"))
        (sha256
-        (base32 "0qqlah4zi0b7b6yb4009kkjqw7fkp1lgvp2mcpxs8vbbshs3376c"))))
+        (base32 "0wcv99xgg9pxijbjl4cmsgmpwb893ira6wd3ys5ihk2nakbvd09x"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools qttools-5))
@@ -3718,7 +3770,7 @@ KParts instead.")
 (define-public kross
   (package
     (name "kross")
-    (version "5.96.0")
+    (version "5.98.0")
     (source
      (origin
        (method url-fetch)
@@ -3727,7 +3779,7 @@ KParts instead.")
              (version-major+minor version) "/portingAids/"
              name "-" version ".tar.xz"))
        (sha256
-        (base32 "03dvg2jh9587kcp2f9nir727z0qvkcywrgxfi1p1hxq1bx6y8fm2"))))
+        (base32 "0yjn66r44jxlrm4vz1nf8s64kcw7lmarjpqz1mcgb1n4jc28hs60"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools qttools-5))
@@ -3760,7 +3812,7 @@ offers abstract functionality to deal with scripts.")
 (define-public kdav
   (package
     (name "kdav")
-    (version "5.96.0")
+    (version "5.98.0")
     (source
      (origin
        (method url-fetch)
@@ -3768,7 +3820,7 @@ offers abstract functionality to deal with scripts.")
                            (version-major+minor version) "/"
                            name "-" version ".tar.xz"))
        (sha256
-        (base32 "1zqib8km4fg9aj4gmhx4hm7n7bbrz62l41qb48nz1pc3qia2x1wl"))))
+        (base32 "02474a3k7yqgnb1sbxbnm6l4cahn88y2631jvkq9xlmcx7xs2dzi"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
diff --git a/gnu/packages/kde-pim.scm b/gnu/packages/kde-pim.scm
index 73edce6c33..19066fd289 100644
--- a/gnu/packages/kde-pim.scm
+++ b/gnu/packages/kde-pim.scm
@@ -22,12 +22,15 @@
 
 (define-module (gnu packages kde-pim)
   #:use-module (guix build-system qt)
+  #:use-module (guix gexp)
   #:use-module (guix download)
+  #:use-module (guix gexp)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (guix packages)
   #:use-module (guix utils)
   #:use-module (gnu packages)
   #:use-module (gnu packages boost)
+  #:use-module (gnu packages compression)
   #:use-module (gnu packages cyrus-sasl)
   #:use-module (gnu packages databases)
   #:use-module (gnu packages documentation)
@@ -37,31 +40,38 @@
   #:use-module (gnu packages kde)
   #:use-module (gnu packages kde-frameworks)
   #:use-module (gnu packages openldap)
+  #:use-module (gnu packages pdf)
+  #:use-module (gnu packages pkg-config)
   #:use-module (gnu packages qt)
   #:use-module (gnu packages search)
   #:use-module (gnu packages sqlite)
+  #:use-module (gnu packages tls)
   #:use-module (gnu packages xml))
 
 (define-public akonadi
   (package
     (name "akonadi")
-    (version "22.04.3")
-    (source
-     (origin
-       (method url-fetch)
-       (uri (string-append "mirror://kde/stable/release-service/" version
-                           "/src/akonadi-" version ".tar.xz"))
-       (sha256
-        (base32 "0g277jl2ay00p4yhkadvzjn1k2rkriz90ql2qcp5d4fjgs0220ky"))
-       (patches (search-patches
-                 "akonadi-paths.patch"
-                 "akonadi-timestamps.patch"
-                 "akonadi-not-relocatable.patch"))))
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/akonadi-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1yfy0b6kyiq82zkfkx9ldgjlbwg3lgg4di53fqjllmqhzaj1xy91"))
+              (patches (search-patches "akonadi-paths.patch"
+                                       "akonadi-timestamps.patch"
+                                       "akonadi-not-relocatable.patch"))))
     (build-system qt-build-system)
     (native-inputs
-     (list extra-cmake-modules qttools-5 shared-mime-info))
+     (list dbus
+           extra-cmake-modules
+           qttools-5
+           shared-mime-info
+           pkg-config))
     (inputs
      (list boost
+           libaccounts-qt
            kconfig
            kconfigwidgets
            kcoreaddons
@@ -79,33 +89,39 @@
            ;; Do NOT add mysql or postgresql to the inputs. Otherwise the binaries
            ;; and wrapped files will refer to them, even if the user choices none
            ;; of these.  Executables are searched on $PATH then.
-           qtbase-5
-           sqlite))
+           signond
+           qtbase-5))
+    (propagated-inputs (list sqlite kaccounts-integration))
     (arguments
-     `(#:tests? #f ;; TODO 135/167 tests fail
-       #:configure-flags '("-DDATABASE_BACKEND=SQLITE") ; lightweight
-       #:modules ((ice-9 textual-ports)
-                  ,@%qt-build-system-modules)
-       #:phases
-       (modify-phases (@ (guix build qt-build-system) %standard-phases)
-         (add-before 'configure 'add-definitions
-           (lambda* (#:key outputs inputs #:allow-other-keys)
-             (let ((out   (assoc-ref outputs "out")))
-               (with-output-to-file "CMakeLists.txt.new"
-                 (lambda _
-                   (display
-                    (string-append
-                     "add_compile_definitions(\n"
-                     "NIX_OUT=\"" out "\"\n"
-                     ;; pin binaries for mysql backend
-                     ")\n\n"))
-                   (display
-                    (call-with-input-file "CMakeLists.txt"
-                      get-string-all))))
-               (rename-file "CMakeLists.txt.new" "CMakeLists.txt")))))))
+     (list #:tests? #f
+           #:configure-flags #~'("-DDATABASE_BACKEND=SQLITE") ;lightweight
+           #:modules `((ice-9 textual-ports)
+                       ,@%qt-build-system-modules)
+           #:phases
+           #~(modify-phases (@ (guix build qt-build-system) %standard-phases)
+               (replace 'check
+                 (lambda* (#:key tests? #:allow-other-keys)
+                   (when tests?
+                     (setenv "PATH"
+                             (string-append (getcwd) "/bin" ":"
+                                            (getenv "PATH")))
+                     (invoke "dbus-launch" "ctest" "-E"
+                             "(AkonadiServer-dbconfigtest|mimetypecheckertest|entitytreemodeltest|akonadi-sqlite-testenvironmenttest|akonadi-sqlite-autoincrementtest|akonadi-sqlite-attributefactorytest|akonadi-sqlite-collectionpathresolvertest|akonadi-sqlite-collectionattributetest|akonadi-sqlite-itemfetchtest|akonadi-sqlite-itemappendtest|akonadi-sqlite-itemstoretest|akonadi-sqlite-itemdeletetest|akonadi-sqlite-entitycachetest|akonadi-sqlite-monitortest|akonadi-sqlite-changerecordertest|akonadi-sqlite-resourcetest|akonadi-sqlite-subscriptiontest|akonadi-sqlite-transactiontest|akonadi-sqlite-itemcopytest|akonadi-sqlite-itemmovetest|akonadi-sqlite-invalidatecachejobtest|akonadi-sqlite-collectioncreatetest|akonadi-sqlite-collectioncopytest|akonadi-sqlite-collectionmovetest|akonadi-sqlite-collectionsynctest|akonadi-sqlite-itemsynctest)"))))
+               (add-before 'configure 'add-definitions
+                 (lambda* (#:key outputs inputs #:allow-other-keys)
+                   (with-output-to-file "CMakeLists.txt.new"
+                     (lambda _
+                       (display (string-append
+                                 "add_compile_definitions(\n"
+                                 "NIX_OUT=\""
+                                 #$output "\"\n" ")\n\n"))
+                       (display (call-with-input-file "CMakeLists.txt"
+                                  get-string-all))))
+                   (rename-file "CMakeLists.txt.new" "CMakeLists.txt"))))))
     (home-page "https://kontact.kde.org/components/akonadi/")
     (synopsis "Extensible cross-desktop storage service for PIM")
-    (description "Akonadi is an extensible cross-desktop Personal Information
+    (description
+     "Akonadi is an extensible cross-desktop Personal Information
 Management (PIM) storage service.  It provides a common framework for
 applications to store and access mail, calendars, addressbooks, and other PIM
 data.
@@ -117,14 +133,14 @@ programs.")
 (define-public akonadi-calendar
   (package
     (name "akonadi-calendar")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/akonadi-calendar-" version ".tar.xz"))
        (sha256
-        (base32 "0hcc2hpyhpd7219my7hpjcl24gsr9g8d2bwhlc66da96ray0pzg4"))))
+        (base32 "1xcnlkipy2rq0bsm811y9khw7dmsgkqxgw18b3lmy29xs7wcsiv5"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -164,14 +180,14 @@ collection and item views.")
 (define-public akonadi-contacts
   (package
     (name "akonadi-contacts")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/akonadi-contacts-" version ".tar.xz"))
        (sha256
-        (base32 "080ba08sxb79il7na97m56k3gpwc8pj4bljca3qgw5kwhswj6gnx"))))
+        (base32 "1mzlv124wa135xfbxl2ghl4n8pi1a6zd64195px1v90qnhjljw28"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -219,14 +235,14 @@ to list and filter contacts.")
 (define-public akonadi-mime
   (package
     (name "akonadi-mime")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/akonadi-mime-" version ".tar.xz"))
        (sha256
-        (base32 "1qggacdhj5b5vrhwp1srlrhapl13hcc5d1ff5wlsdip87in4jad1"))))
+        (base32 "19wbfkvhkyzlz5r49y7rzbn4ay7rm8zyj7d4j3x9j79nprjr4zw0"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules libxslt ;; xslt for generating interface descriptions
@@ -269,14 +285,14 @@ with emails through Akonadi easier.")
 (define-public akonadi-notes
   (package
     (name "akonadi-notes")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/akonadi-notes-" version ".tar.xz"))
        (sha256
-        (base32 "0ps99717hvsq62fh3zagn5xgw5sc99naiiay5ym9wmfjvhr5slml"))))
+        (base32 "05sx7h1aw4mx93l4krv4574zpjf63vdrhaiwayqz11wrdpvdq7ww"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -294,14 +310,14 @@ wrapping notes into KMime::Message objects.")
 (define-public akonadi-search
   (package
     (name "akonadi-search")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/akonadi-search-" version ".tar.xz"))
        (sha256
-        (base32 "0jpirnnpab6ki2gf5vlzklp04rwm05l8phlzajp2apcddb84lqvm"))))
+        (base32 "06apb5lx7bs0lfvsnbf8kyxk7yyjrzb1f1wfckfsjaysf0xmdvfg"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules
@@ -346,17 +362,71 @@ Akonadi PIM data server.  It uses Xapian for indexing and querying.")
     (license ;; GPL for programs, LGPL for libraries
      (list license:gpl2+ license:lgpl2.0+))))
 
+(define-public itinerary
+  (package
+    (name "itinerary")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1w1gl4lz8gwf8cmxhsfyp4afiaq9anc8glrxay407bqp28andp3a"))))
+    (build-system qt-build-system)
+    (arguments
+     `(#:tests? #f)) ;Fails 20/27
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list karchive
+                  kdbusaddons
+                  ki18n
+                  kio
+                  kirigami
+                  kitinerary
+                  kitemmodels
+                  kcoreaddons
+                  kcontacts
+                  kholidays
+                  kmime
+                  knotifications
+                  kpublictransport
+                  kcalendarcore
+                  khealthcertificate
+                  kosmindoormap
+                  kopeninghours
+                  kpkpass
+                  kunitconversion
+                  kwindowsystem
+                  prison
+                  qtdeclarative-5
+                  qtgraphicaleffects
+                  qtlocation
+                  qtmultimedia-5
+                  qtquickcontrols2-5
+                  qqc2-desktop-style
+                  shared-mime-info
+                  solid
+                  sonnet
+                  zlib))
+    (home-page "https://invent.kde.org/pim/itinerary")
+    (synopsis "Itinerary and boarding pass management")
+    (description
+     "This package provides a tool for managing itinerary and boarding pass
+information.")
+    (license ;GPL for programs, LGPL for libraries
+             (list license:gpl2+ license:lgpl2.0+))))
+
 (define-public kincidenceeditor
   (package
     (name "kincidenceeditor")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/incidenceeditor-" version ".tar.xz"))
        (sha256
-        (base32 "0bm25r3l9d1qhlkxz7pd5hmg6xd0y651q8any4q71bd6a023ps0b"))))
+        (base32 "1znbpqpxkbn79pzhcg5v77bqr345lcmy2h0a6d90rzdmnlh303ln"))))
     (properties `((upstream-name . "incidenceeditor")))
     (build-system qt-build-system)
     (native-inputs
@@ -410,14 +480,14 @@ Akonadi PIM data server.  It uses Xapian for indexing and querying.")
 (define-public kaddressbook
   (package
     (name "kaddressbook")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kaddressbook-" version ".tar.xz"))
        (sha256
-        (base32 "18f6xjcmqgslrw12dik9immw3mw0krvzi6y6f0ryr2ry1shqvivb"))))
+        (base32 "177zgbpgignvglpvbis1q9d36pi1dvyckv3q2gcgd9425gpm0vmb"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools))
@@ -496,17 +566,115 @@ modern blogging web application that provides an XML data interface supports
 one of the APIs mentioned above.")
     (license license:lgpl2.0+)))
 
+(define-public kaccounts-integration
+  (package
+    (name "kaccounts-integration")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1q1d2a1qknfkgm63gji6ijji35d0b1jy1kvf10a7ac4l1z1fvnpl"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kcmutils
+                  ki18n
+                  kcoreaddons
+                  kdbusaddons
+                  kdeclarative
+                  kwallet
+                  kio
+                  libaccounts-qt
+                  signond))
+    (home-page "https://invent.kde.org/network/kaccounts-integration")
+    (synopsis "Online account management system")
+    (description "The Kaccounts Integration library provides online account
+management system and its Plasma integration components.")
+    (license license:lgpl2.0+)))
+
+(define-public kalendar
+  (package
+    (name "kalendar")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/" name "-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "0slk9z7p1z5m2kbb8kq05afslxad8w5pjsajxawckcx0mlsd3apj"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:tests? #f ;All 2 tests fail
+           #:phases
+           #~(modify-phases %standard-phases
+               (add-after 'install 'wrap-script
+                 (lambda* (#:key inputs outputs #:allow-other-keys)
+                   (wrap-program (string-append #$output
+                                                "/bin/kalendar")
+                     `("PATH" ":" prefix
+                       (,(string-append #$(this-package-input "akonadi")
+                                        "/bin"))))))
+               (delete 'check)
+               (add-after 'wrap-script 'check-again
+                 (lambda* (#:key tests? #:allow-other-keys)
+                   (when tests?
+                     (invoke "dbus-launch" "ctest")))))))
+    (native-inputs (list dbus extra-cmake-modules))
+    (inputs (list akonadi
+                  akonadi-contacts
+                  breeze-icons
+                  grantlee
+                  grantleetheme
+                  kio
+                  kirigami
+                  kdbusaddons
+                  ki18n
+                  kcalendarcore
+                  kcalendarsupport
+                  kconfigwidgets
+                  kwindowsystem
+                  kcoreaddons
+                  kcontacts
+                  kitemmodels
+                  kmime
+                  kidentitymanagement
+                  kpimtextedit
+                  ktextwidgets
+                  akonadi-calendar
+                  keventviews
+                  kcalutils
+                  kxmlgui
+                  kiconthemes
+                  qtbase-5
+                  qtdeclarative-5
+                  qtquickcontrols2-5
+                  qtsvg-5
+                  qtquickcontrols-5
+                  qtgraphicaleffects
+                  qtlocation
+                  qqc2-desktop-style))
+    (home-page "https://apps.kde.org/kalendar/")
+    (synopsis "Calendar application")
+    (description
+     "Kalendar is a calendar application using Akonadi to sync with
+external services.")
+    (license license:gpl3+)))
+
 (define-public kcalendarsupport
   (package
     (name "kcalendarsupport")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/calendarsupport-" version ".tar.xz"))
        (sha256
-        (base32 "05x5ps15hkbv0cm4am859wzf6r5yiyaadidw3617qcim4sh5smqd"))))
+        (base32 "09fs15qckydmbs6idl5k1b6gyhjkygsa1r8frlysn1ahhfmxr33p"))))
     (properties `((upstream-name . "calendarsupport")))
     (build-system qt-build-system)
     (native-inputs
@@ -544,14 +712,14 @@ calendaring applications.")
 (define-public kcalutils
   (package
     (name "kcalutils")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kcalutils-" version ".tar.xz"))
        (sha256
-        (base32 "1vv2nv4yc2hwi31b9k0jcxmxgbpaalmdc06jhbcq8qbi20pj70kh"))))
+        (base32 "1y25csn37lp14ba18gqmw9ssimy4dqi55irx8c89p4p1lypjwfzq"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules libxml2)) ;; xmllint required for tests
@@ -582,14 +750,14 @@ functions for accessing calendar data using the kcalcore API.")
 (define-public kdepim-runtime
   (package
     (name "kdepim-runtime")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kdepim-runtime-" version ".tar.xz"))
        (sha256
-        (base32 "1lhkcfdjnxlm8amfczw4pi41grlq951pd67cj1z51whs6b84an27"))))
+        (base32 "1g6bq27s7nf9rmrbl5kwycl4lzjpp3m088mji3p7qrrv01ywp4mn"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules dbus kdoctools libxslt shared-mime-info))
@@ -677,14 +845,14 @@ package.")
 (define-public keventviews
   (package
     (name "keventviews")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/eventviews-" version ".tar.xz"))
        (sha256
-        (base32 "1346k5fvjdgxhfjhf0mbc7s559ampxc2vfg0i4wk1a6n6d4jpmcr"))))
+        (base32 "0bkidva045q85z4ymhj4m9ayfbsckjl4cl7nncl48yk2dmanfg51"))))
     (properties `((upstream-name . "eventviews")))
     (build-system qt-build-system)
     (native-inputs
@@ -726,14 +894,14 @@ package.")
 (define-public kgpg
   (package
     (name "kgpg")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kgpg-" version ".tar.xz"))
        (sha256
-        (base32 "196xgbvc68jzacal4wwxgdrwxyiyr49hq0h2dwpzq5yhpfh3fcrw"))))
+        (base32 "1xs0w6lxwq3hzs8r1cwmygcjilbgwa8zpjxwj6zz1wmbg04gqk36"))))
     (build-system qt-build-system)
     (arguments
      `(#:phases
@@ -781,17 +949,51 @@ for applying cryptography to short pieces of text, and can also quickly apply
 cryptography to the contents of the clipboard.")
     (license license:gpl2+)))
 
+(define-public khealthcertificate
+  (package
+    (name "khealthcertificate")
+    (version "22.09")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma-mobile/"
+                                  (version-major+minor version)
+                                  "/khealthcertificate-" version ".tar.xz"))
+              (sha256
+               (base32
+                "16vkjpyxwx34pvdpnci0l6mx2bdjialiscjvbdx53xbsq9ff701k"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (invoke "ctest" "-E"
+                               "(icaovdsparsertest|nlcoronacheckparsertest)")))))))
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list karchive
+                  kcodecs
+                  ki18n
+                  openssl
+                  qtdeclarative-5
+                  zlib))
+    (home-page "https://api.kde.org/khealthcertificate/html/index.html")
+    (synopsis "Digital vaccination and recovery certificate library")
+    (description
+     "This package provides a library for arsing of digital vaccination,
+test and recovery certificates.")
+    (license license:lgpl2.0)))
+
 (define-public kidentitymanagement
   (package
     (name "kidentitymanagement")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kidentitymanagement-" version ".tar.xz"))
        (sha256
-        (base32 "0z1ixwlrdm7dzfxszphf2wma0gjprr0143c46li79g5gzvcrid8w"))))
+        (base32 "1h76c8k6lvf4dlh9awd4z71hkikm7x71760gljybd6fkygxpm992"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -822,14 +1024,14 @@ cryptography to the contents of the clipboard.")
 (define-public kimap
   (package
     (name "kimap")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kimap-" version ".tar.xz"))
        (sha256
-        (base32 "1k5h7jmzxg8wq58iqk0f1gx5r45pr2895vl7y5ihyav9w0qfqcn0"))))
+        (base32 "1a3wwzwlp0zsj4brhs22sygfxh65slikapa4iipxjw78mkwhiq8h"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -850,17 +1052,62 @@ easier to do so.")
     (license ;; GPL for programs, LGPL for libraries
      (list license:gpl2+ license:lgpl2.0+))))
 
+(define-public kitinerary
+  (package
+    (name "kitinerary")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append
+                    "https://invent.kde.org/pim/kitinerary/-/archive/v"
+                    version "/kitinerary-v" version ".tar.gz"))
+              (sha256
+               (base32
+                "1gpy5siaw9k4332ii6a87rq162dbmyfkqp1l1k8bmldg1755v3jz"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (invoke "dbus-launch" "ctest" "-E"
+                               "(jsonlddocumenttest|mergeutiltest|locationutiltest|knowledgedbtest|airportdbtest|extractorscriptenginetest|pkpassextractortest|postprocessortest|calendarhandlertest|extractortest)")))))))
+    (native-inputs (list dbus extra-cmake-modules))
+    (inputs (list kpkpass
+                  kcalendarcore
+                  karchive
+                  ki18n
+                  kcoreaddons
+                  kcontacts
+                  kmime
+                  knotifications
+                  shared-mime-info
+                  openssl
+                  poppler
+                  qtbase-5
+                  qtdeclarative-5
+                  qtlocation
+                  qtquickcontrols2-5
+                  libxml2
+                  zlib))
+    (home-page "https://apps.kde.org/itinerary/")
+    (synopsis
+     "Data Model and Extraction System for Travel Reservation information")
+    (description "This package provides a library containing itinerary data
+model and itinerary extraction code.")
+    (license license:lgpl2.0)))
+
 (define-public kldap
   (package
     (name "kldap")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kldap-" version ".tar.xz"))
        (sha256
-        (base32 "024xgjffz5n8zz6js06i78pf8s3nd5sbmvhzz7bm3qc05xqxyp75"))))
+        (base32 "0hqvf939d2sqb2frizw9pnhgpc8vi627882d30ssymw5p5nm58il"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools))
@@ -878,21 +1125,21 @@ protocol for querying and modifying directory services running over TCP/IP.")
 (define-public kleopatra
   (package
     (name "kleopatra")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kleopatra-" version ".tar.xz"))
        (sha256
-        (base32 "1dp421hniyknggirpqqdb7pmsrbidz9qshmd3qnsqvcr9pz301d5"))))
+        (base32 "1vay6cdrx1l7qyg0rrc7z7rwv1jjpwksqzadka7rpshfqhf3r9y8"))))
     (build-system qt-build-system)
     (native-inputs
      (list dbus extra-cmake-modules gnupg ;; TODO: Remove after gpgme uses fixed path
            kdoctools))
     (inputs
      (list boost
-           gpgme
+           gpgme-1.18
            kcmutils
            kcodecs
            kconfig
@@ -912,7 +1159,7 @@ protocol for querying and modifying directory services running over TCP/IP.")
            libassuan
            libkleo
            breeze-icons ;; default icon set
-           qgpgme
+           qgpgme-1.18
            qtbase-5))
     (arguments
      `(#:phases
@@ -932,14 +1179,14 @@ and retrieving certificates from LDAP servers.")
 (define-public kmail
   (package
     (name "kmail")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kmail-" version ".tar.xz"))
        (sha256
-        (base32 "0x2d8w8hlb62h9q9qkh3cwyg7pwwl7px1rf89vyfp9arfbs030dq"))))
+        (base32 "1q7d2jazc6792dhwxb2zx66bghdnn43sw6lvdg44a7d9zgik1qzb"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules dbus kdoctools))
@@ -949,7 +1196,7 @@ and retrieving certificates from LDAP servers.")
            akonadi-mime
            akonadi-search
            boost
-           gpgme
+           gpgme-1.18
            grantlee
            grantleetheme
            kbookmarks
@@ -996,7 +1243,7 @@ and retrieving certificates from LDAP servers.")
            libkleo
            libksieve
            breeze-icons ; default icon set, required for tests
-           qgpgme
+           qgpgme-1.18
            qtbase-5
            qtdeclarative-5
            qtkeychain
@@ -1032,14 +1279,14 @@ manager from KDE.")
 (define-public kmailcommon
   (package
     (name "kmailcommon")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/mailcommon-" version ".tar.xz"))
        (sha256
-        (base32 "0vir2p7akihfzb86iwspz3k6j3psc6xxyak4x738dw3lhn22nfzb"))))
+        (base32 "1lpnfcj2p58lhgcjg6ray5b9ygz7gpb8xh8qkakn4m7cpjhgcj5j"))))
     (properties `((upstream-name . "mailcommon")))
     (build-system qt-build-system)
     (native-inputs
@@ -1086,6 +1333,8 @@ manager from KDE.")
            libxslt
            phonon
            qgpgme
+           qtwebchannel-5
+           qtwebengine-5
            qtbase-5))
     (arguments
      `(#:tests? #f))  ;; TODO: 12/62 tests fail
@@ -1099,14 +1348,14 @@ dealing with email.")
 (define-public kmailimporter
   (package
     (name "kmailimporter")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/mailimporter-" version ".tar.xz"))
        (sha256
-        (base32 "0hb4ba8vr7wrw8mcrc7hicl8f9r6ihsbwkxxr1qkzk0310yjmcbf"))))
+        (base32 "1k7gwagcvhj733c48ayxwi1gf37y6w5g6n2b9fknhfs40kqpdri9"))))
     (properties `((upstream-name . "mailimporter")))
     (build-system qt-build-system)
     (native-inputs
@@ -1146,14 +1395,14 @@ e-mail client programs into KMail and KDE PIM.")
 (define-public kmailtransport
   (package
     (name "kmailtransport")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kmailtransport-" version ".tar.xz"))
        (sha256
-        (base32 "0fcgwln40d9h3r4m58mp4m79k425hianjz0ambqckdzp0aspkhzp"))))
+        (base32 "0hhd1m1kfagyiwwfmsxhpin5c25dsiwbzg188khppn6fp2dh79dg"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools))
@@ -1188,14 +1437,14 @@ mail transport.")
 (define-public kmbox
   (package
     (name "kmbox")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kmbox-" version ".tar.xz"))
        (sha256
-        (base32 "0d3i36zkn3apcjqkbsq633mgrk382xgx8knfg6fkyyc8i55p3dig"))))
+        (base32 "0n49xqgyx40hml9554zvnycff26qki9fdy32awx9v9l8jbnrmm6p"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1210,14 +1459,14 @@ using a Qt/KMime C++ API.")
 (define-public kmessagelib
   (package
     (name "kmessagelib")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/messagelib-" version ".tar.xz"))
        (sha256
-        (base32 "06vsba8r9sh94y59hmkh8nbg8xhib83sv80qnfw4g9fv5gfjppjh"))))
+        (base32 "0xq1a064g3h3igrqanfald9n21nnrsg16a4kmn9vn1k03qv1vlp2"))))
     (properties `((upstream-name . "messagelib")))
     (build-system qt-build-system)
     (native-inputs
@@ -1296,14 +1545,14 @@ kwebengineviewer.")
 (define-public kmime
   (package
     (name "kmime")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kmime-" version ".tar.xz"))
        (sha256
-        (base32 "1k9lvq3a728015laj7rklg136hgg256l4snarnc5cw97ijqdm5ng"))))
+        (base32 "1vz5gw33ncc5lx8fx2nnp8ayxpdhfjwwx226gwa94vhxxkfcnmh4"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1331,14 +1580,14 @@ information in non-ASCII character sets.")
 (define-public knotes
   (package
     (name "knotes")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/knotes-" version ".tar.xz"))
        (sha256
-        (base32 "1bbrcr2s5am7gq3im5s9kk63nrsgz0kfkm3qzhasafnz06zhf1vf"))))
+        (base32 "076rwgkwx67rn6z0mj0sj77h1jngcpbvrwka3ijg2309r9f2wg8h"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools libxslt))
@@ -1401,14 +1650,14 @@ Features:
 (define-public kontactinterface
   (package
     (name "kontactinterface")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kontactinterface-" version ".tar.xz"))
        (sha256
-        (base32 "0npaxlrvgpg2p8wdaqs03k2gyppbid81k64q6cawin6wrn6zzc9m"))))
+        (base32 "0j7cck262j8z7m7fm55qa5i936x81ljn3cijrk5c5h881152h4fs"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1429,14 +1678,14 @@ application \"Parts\" to be embedded as a Kontact component (or plugin).")
 (define-public korganizer
   (package
     (name "korganizer")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/korganizer-" version ".tar.xz"))
        (sha256
-        (base32 "0ypscdr0la4pdxz491mryjmg535d0g7c4r62y0l7an5g1ribrjq9"))))
+        (base32 "0pcyij50k96mrm9vkq0pzr7n0nrgy1d51zrcb3hly7fpl4gvkx4x"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules dbus qttools-5 kdoctools))
@@ -1547,17 +1796,37 @@ and exchanging calendar data, vCalendar and iCalendar.")
 Virtual Contact File}) files to the KPeople contact management library.")
     (license license:lgpl2.1+)))
 
+(define-public kpkpass
+  (package
+    (name "kpkpass")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/" version
+                           "/src/kpkpass-" version ".tar.xz"))
+              (sha256
+               (base32
+                "09l6c7nsgfnffgkm0yzjhsfkm79fv9izasislrlzdvca5xninrgb"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list karchive qtbase-5 shared-mime-info))
+    (home-page "https://invent.kde.org/pim/kpkpass")
+    (synopsis "Apple Wallet Pass reader")
+    (description "This package provides library to deal with Apple Wallet
+pass files.")
+    (license license:lgpl2.0+)))
+
 (define-public kpimcommon
   (package
     (name "kpimcommon")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/pimcommon-" version ".tar.xz"))
        (sha256
-        (base32 "1xns3qc5n5fig898bsj3kzda6484n0r406km43gicnly1m7jpar9"))))
+        (base32 "00gxv1028xdp7ag44z9h6cpmlw55f3rk7i6msymga3pdq639c19y"))))
     (properties `((upstream-name . "pimcommon")))
     (build-system qt-build-system)
     (native-inputs
@@ -1613,14 +1882,14 @@ Virtual Contact File}) files to the KPeople contact management library.")
 (define-public libgravatar
   (package
     (name "libgravatar")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/libgravatar-" version ".tar.xz"))
        (sha256
-        (base32 "1zik4y1micgqyz2y6cj5w5sjccm69d49svl72bdjcj5n3r6xl9iq"))))
+        (base32 "1yhmxl2gqwrn5flr5qm56aqg6rgmqbgcr3pyb4d0vshdfksjr4rc"))))
     (build-system qt-build-system)
     (native-inputs (list extra-cmake-modules))
     (inputs (list kconfig
@@ -1644,14 +1913,14 @@ unnecessary network operations.")
 (define-public kpimtextedit
   (package
     (name "kpimtextedit")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/kpimtextedit-" version ".tar.xz"))
        (sha256
-        (base32 "1gb0n8nrx673ya3mgkjs6khjlz7472a932lgpy5pwir48mc57g1d"))))
+        (base32 "1dxdlspqssxnvha202bgh9yaszs77cph5qd9wcbd45xj07dqgbw1"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -1685,14 +1954,14 @@ text in the text edit to all kinds of markup, like HTML or BBCODE.")
 (define-public ksmtp
   (package
     (name "ksmtp")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/ksmtp-" version ".tar.xz"))
        (sha256
-        (base32 "1l0w7yxmmvkj2wbv49yf73b2ca7k0yxrishkdqgm3q5crahg8l4z"))))
+        (base32 "13ybnr39pim3r83p56wj98fwj0yk1rspd9g24a8d0qykmnbx57l3"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1724,14 +1993,14 @@ standard protocols for e-mail transmission.")
 (define-public ktnef
   (package
     (name "ktnef")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/ktnef-" version ".tar.xz"))
        (sha256
-        (base32 "0nvvaakjhciqdn0v1697d559p0py5v41iyd0ix2z8sqgw7lb7nkh"))))
+        (base32 "05rcs0m4dr4p4wxigcnhjmmp15nlf36ka85v8b8gd8630v61w6y6"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1756,14 +2025,14 @@ and allows one to view/extract message formatted text in Rich Text Format.")
 (define-public libkdepim
   (package
     (name "libkdepim")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/libkdepim-" version ".tar.xz"))
        (sha256
-        (base32 "1r6hbj3rgma1q1fxmi982widvnq1dajslhwmd21aknnnryspfx7s"))))
+        (base32 "07ihnps983x3sp74yq5glsq3h3jw4k80mnc4xxzm6ps2vgswah12"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -1803,14 +2072,14 @@ and allows one to view/extract message formatted text in Rich Text Format.")
 (define-public libkgapi
   (package
     (name "libkgapi")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/libkgapi-" version ".tar.xz"))
        (sha256
-        (base32 "0m47wqr2m147csypzm38i29msm1mcnn6mx3l0nwfhwsmycf6lsr7"))))
+        (base32 "065441mbl67wyp4nz03jdygkn5wmnmkj4fiql4mnq99k2v80y0ka"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules qttools-5))
@@ -1838,14 +2107,14 @@ various Google services.")
 (define-public libkleo
   (package
     (name "libkleo")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/libkleo-" version ".tar.xz"))
        (sha256
-        (base32 "0nk6bi2z4s0rf0qim00xcmvxyzwax4bjn1f4f6iyw5qdfkc6yvnp"))))
+        (base32 "05ypgrwynm1hr32hj35faj3sxabi46x8slnbs3pxwz2f2z2ry58a"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools qttools-5))
@@ -1855,6 +2124,7 @@ various Google services.")
            kcodecs
            kcompletion
            kconfig
+           kconfigwidgets
            kcoreaddons
            kcrash
            ki18n
@@ -1885,7 +2155,7 @@ KDE using certificate-based crypto.")
 (define-public libksieve
   (package
     (name "libksieve")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
@@ -1893,7 +2163,7 @@ KDE using certificate-based crypto.")
                            "/src/libksieve-" version ".tar.xz"))
        (sha256
         (base32
-		"0s5c49vgsqmbpyk1bhwjb04v6v6vb9xlcms8dvc6f3gyjdchk5lc"))))
+		"1ia1gjx8x9ym3dml3y403kif50jhcsrqmhivn3j5yxf8abc3rnk6"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools))
@@ -1930,7 +2200,7 @@ KDE using certificate-based crypto.")
              ;; sieveeditorhelphtmlwidgettest fails with `sigtrap`
              (substitute*
                  "src/ksieveui/editor/webengine/autotests/CMakeLists.txt"
-               (("^\\s*(add_test|ecm_mark_as_test)\\W" line)
+               (("^\\s*(add_test|ecm_mark_as_test|set_tests_properties)\\W" line)
                 (string-append "# " line))))))))
     (home-page "https://invent.kde.org/pim/libksieve")
     (synopsis "KDE Sieve library")
diff --git a/gnu/packages/kde-plasma.scm b/gnu/packages/kde-plasma.scm
index 2b88ea2afe..5af37e8de0 100644
--- a/gnu/packages/kde-plasma.scm
+++ b/gnu/packages/kde-plasma.scm
@@ -6,6 +6,7 @@
 ;;; Copyright © 2019 Tobias Geerinckx-Rice <me@tobias.gr>
 ;;; Copyright © 2020 Zheng Junjie <873216071@qq.com>
 ;;; Copyright © 2022 Brendan Tildesley <mail@brendan.scot>
+;;; Copyright © 2022 Petr Hodina <phodina@protonmail.com>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -25,35 +26,101 @@
 (define-module (gnu packages kde-plasma)
   #:use-module (guix packages)
   #:use-module (guix download)
+  #:use-module (guix git-download)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (guix gexp)
   #:use-module (guix build-system cmake)
+  #:use-module (guix build-system copy)
+  #:use-module (guix build-system trivial)
   #:use-module (guix build-system qt)
+  #:use-module (gnu packages)
   #:use-module (gnu packages admin)
+  #:use-module (gnu packages bash)
+  #:use-module (gnu packages boost)
+  #:use-module (gnu packages authentication)
+  #:use-module (gnu packages bash)
   #:use-module (gnu packages compression)
+  #:use-module (gnu packages display-managers)
+  #:use-module (gnu packages firmware)
+  #:use-module (gnu packages fontutils)
   #:use-module (gnu packages freedesktop)
+  #:use-module (gnu packages ghostscript)
+  #:use-module (gnu packages gnupg)
+  #:use-module (gnu packages gl)
   #:use-module (gnu packages glib)
+  #:use-module (gnu packages gnome)
   #:use-module (gnu packages gtk)
+  #:use-module (gnu packages ibus)
+  #:use-module (gnu packages iso-codes)
+  #:use-module (gnu packages kde)
   #:use-module (gnu packages kde-frameworks)
+  #:use-module (gnu packages kde-pim)
+  ;; Including this module breaks the build
+  ;#:use-module ((gnu packages kde-systemtools) #:select (konsole))
+  #:use-module (gnu packages libcanberra)
   #:use-module (gnu packages linux)
+  #:use-module (gnu packages libusb)
+  #:use-module (gnu packages networking)
+  #:use-module (gnu packages maths)
+  #:use-module (gnu packages messaging)
+  #:use-module (gnu packages multiprecision)
+  #:use-module (gnu packages pciutils)
   #:use-module (gnu packages pkg-config)
+  #:use-module (gnu packages polkit)
+  #:use-module (gnu packages pulseaudio)
   #:use-module (gnu packages python)
+  #:use-module (gnu packages package-management) ; flatpak
+  #:use-module (gnu packages video)
+  #:use-module (gnu packages vpn)
+  #:use-module (gnu packages vulkan)
+  #:use-module (gnu packages textutils)
   #:use-module (gnu packages qt)
   #:use-module (gnu packages xdisorg)
   #:use-module (gnu packages xorg)
   #:use-module (gnu packages web))
 
+(define-public bluedevil
+  (package
+    (name "bluedevil")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version "/"
+                                  name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1dsah7rcx2brcd1d5x7bvhrixx5nvwp1fwq9b8k2zc038xzpx6ys"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config qttools-5))
+    (inputs (list kcoreaddons
+                  kwidgetsaddons
+                  kdbusaddons
+                  knotifications
+                  kwindowsystem
+                  plasma-framework
+                  ki18n
+                  kio
+                  kdeclarative
+                  bluez-qt
+                  shared-mime-info
+                  qtdeclarative-5))
+    (synopsis "Manage the Bluetooth settings from Plasma")
+    (description
+     "This package provides Bluetooth manager for Plasma Shell.")
+    (home-page "https://invent.kde.org/plasma/bluedevil")
+    (license (list license:lgpl2.1 license:lgpl3))))
+
 (define-public breeze
   (package
     (name "breeze")
-    (version "5.25.3")
+    (version "5.25.5")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://kde/stable/plasma/" version "/"
                                   name "-" version ".tar.xz"))
               (sha256
                (base32
-                "0za75ckgfcdxrh2qxgyl2c1273g2xqwmd55njsis1yvwryadypqw"))))
+                "0m3ggv5znzfcp25afgl7v5w7m27v5hdvv6jw9vrvwbqj8lzq1hlx"))))
     (build-system qt-build-system)
     ;; TODO: Warning at /gnu/store/…-kpackage-5.34.0/…/KF5PackageMacros.cmake:
     ;;   warnings during generation of metainfo for org.kde.breezedark.desktop:
@@ -93,7 +160,7 @@ the Plasma Desktop.  Breeze is the default theme for the KDE Plasma desktop.")
 (define-public breeze-gtk
   (package
     (name "breeze-gtk")
-    (version "5.19.5")
+    (version "5.25.5")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://kde/stable/plasma/"
@@ -101,7 +168,7 @@ the Plasma Desktop.  Breeze is the default theme for the KDE Plasma desktop.")
                                   "-" version ".tar.xz"))
               (sha256
                (base32
-                "1j2nq9yw1ragmgwrz9f6ca4ifpi86qv1bbprdgd2qm2yh7vb44sj"))))
+                "0wj8qzy2104ggczxagxm45zwsvvpwd6jjnbv1893mhlr6f2zrbmh"))))
     (build-system qt-build-system)
     (arguments
      '(#:tests? #f))                              ;no 'test' target
@@ -114,17 +181,186 @@ Breeze is the default theme for the KDE Plasma desktop.")
     (license (list license:bsd-3                  ;cmake/FindSass.cmake
                    license:lgpl2.1+))))           ;<all other files>
 
+(define-public calindori
+  (package
+    (name "calindori")
+    (version "22.09")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma-mobile/" version
+                                  "/calindori-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1pwgdqznp76mhk0ikzjhy3c67qgk91kgv69ygqwzlh5hwiw5sl4n"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kconfig
+                  kcoreaddons
+                  kdbusaddons
+                  ki18n
+                  kirigami
+                  kcalendarcore
+                  knotifications
+                  kpeople
+                  qtbase-5
+                  qtdeclarative-5
+                  qtquickcontrols2-5
+                  qtsvg-5
+                  qtgraphicaleffects))
+    (home-page "https://invent.kde.org/plasma-mobile/calindori")
+    (synopsis "Calendar for Plasma Mobile")
+    (description
+     "This package provides a touch friendly calendar application.")
+    (license license:gpl3+)))
+
+(define-public discover
+  (package
+    (name "discover")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version
+                                  "/"
+                                  name
+                                  "-"
+                                  version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "01vdi66c7v60db25p0qi0q73wgqw6dy2kirbk34bvhld41gpxhhv"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases
+           #~(modify-phases %standard-phases
+               (add-before 'configure 'set-LDFLAGS
+                 (lambda _
+                   (setenv "LDFLAGS" (string-append "-Wl,-rpath=" #$output
+                                                    "/lib/plasma-discover"))))
+               (replace 'check
+                 (lambda* (#:key tests? #:allow-other-keys)
+                   (when tests?
+                     (invoke "ctest" "-E" "knsbackendtest")))))))
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list appstream-qt
+                  attica
+                  fwupd ; optional
+                  flatpak ; optional
+                  kcoreaddons
+                  kconfig
+                  kcrash
+                  kdbusaddons
+                  ki18n
+                  karchive
+                  kxmlgui
+                  kirigami
+                  kuserfeedback
+                  knewstuff
+                  knotifications
+                  kio
+                  kdeclarative
+                  kcmutils
+                  kidletime
+                  packagekit-qt5
+                  qtdeclarative-5
+                  qtgraphicaleffects
+                  qtquickcontrols2-5))
+    ;; -- The following features have been disabled:
+    ;; * Ostree, Library to manage ostree repository. Required to build the rpm-ostree backend
+    ;; * RpmOstree, rpm-ostree binary to manage the system. Required to build the rpm-ostree backend
+    ;;
+    ;; -- The following OPTIONAL packages have not been found:
+    ;; * Snapd, Library that exposes Snapd, <https://www.snapcraft.io>
+    ;; Required to build the Snap backend
+    (synopsis "KDE and Plasma resources management GUI")
+    (description
+     "This package provides a way to find and install applications,
+games, and tools.")
+    (home-page "https://invent.kde.org/plasma/discover")
+    (license (list license:gpl2 license:gpl3))))
+
+(define-public drkonqi
+  (package
+    (name "drkonqi")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "0vw4bfld2jdiwm4g3008x8s1lq1ydf87ckb0fvyzsp11hq9nnnk7"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (invoke "ctest" "-E" "connectiontest")))))))
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list ki18n
+                  kcoreaddons
+                  kconfig
+                  kservice
+                  kdeclarative
+                  kjobwidgets
+                  kio
+                  kcrash
+                  kcompletion
+                  kwidgetsaddons
+                  kwallet
+                  knotifications
+                  kidletime
+                  kwindowsystem
+                  ksyntaxhighlighting
+                  qtdeclarative-5))
+    (synopsis "Crash handler for KDE software")
+    (description "This package provides an automatic handler for crashed apps.")
+    (home-page "https://invent.kde.org/plasma/drkonqi")
+    (license license:gpl2+)))
+
+(define-public kactivitymanagerd
+  (package
+    (name "kactivitymanagerd")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "0hsllhqi46n25sr27crnad053ghk3hni2w496g6d2qfmi20l3g4n"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list boost
+                  kconfig
+                  kcoreaddons
+                  kwindowsystem
+                  kglobalaccel
+                  kio
+                  kxmlgui
+                  kdbusaddons
+                  ki18n
+                  kcrash))
+    (synopsis "System service to manage user's activities")
+    (description "This package provides components for managing the KDE Activity
+concept.")
+    (home-page "https://invent.kde.org/plasma/kactivitymanagerd")
+    (license (list license:gpl2 license:gpl3))))
+
 (define-public kdecoration
   (package
     (name "kdecoration")
-    (version "5.25.3")
+    (version "5.25.5")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://kde/stable/plasma/" version
                                   "/kdecoration-" version ".tar.xz"))
               (sha256
                (base32
-                "0b6ynqkndmlac89hv339k365m7wykp9y238df62jlq4vpr1r9x9y"))))
+                "1x3scszz5nfwqciwc3bv0r04wgqlxs0c9j1090zvn6mjjg2nsyb7"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -137,17 +373,326 @@ These window decorations can be used by for example an X11 based window
 manager which re-parents a Client window to a window decoration frame.")
     (license license:lgpl3+)))
 
+(define-public kde-cli-tools
+  (package
+    (name "kde-cli-tools")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-" version ".tar.xz"))
+              (patches (search-patches "kde-cli-tools-delay-mime-db.patch"))
+              (sha256
+               (base32
+                "0i1lnkyb2bdvbhnr2wsgjy2sjichzxxqkvn30ca85rj21cavk2z3"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:tests? #f ;TODO: Failing sub-tests 3/7
+           #:phases
+           #~(modify-phases %standard-phases
+               (add-after 'unpack 'set-writable-location
+                 (lambda* _
+                   (substitute* "keditfiletype/tests/filetypestest.cpp"
+                     (("QStandardPaths::writableLocation.QStandardPaths::\
+GenericDataLocation.")
+                      (string-append "\"" (getcwd) "/\"")))))
+               (add-before 'check 'setup-env
+                 (lambda* _
+                   (setenv "HOME" (getcwd)))))))
+    (native-inputs (list extra-cmake-modules pkg-config shared-mime-info))
+    (inputs (list kconfig
+                  kdesu
+                  kdoctools
+                  kiconthemes
+                  ki18n
+                  kcmutils
+                  kio
+                  kservice
+                  kwindowsystem
+                  kactivities
+                  kparts
+                  plasma-workspace
+                  qtx11extras
+                  qtsvg-5))
+    (synopsis "CLI tools for interacting with KDE")
+    (description "This package provides command-line tools based on
+KDE Frameworks 5 to better interact with the system.")
+    (home-page "https://invent.kde.org/plasma/kde-cli-tools")
+    (license license:lgpl2.0+)))
+
+(define-public kdeplasma-addons
+  (package
+    (name "kdeplasma-addons")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1a5cq0jz69hlcr22wxi2p5mzxv5xcp88220irxmq0dhpk85kywlx"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (invoke "ctest" "-E"
+                               "(converterrunnertest|spellcheckrunnertest)")))))))
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list karchive
+                  kconfig
+                  kcoreaddons
+                  kdeclarative
+                  kholidays
+                  ki18n
+                  kio
+                  kcmutils
+                  knotifications
+                  krunner
+                  kservice
+                  kunitconversion
+                  knewstuff
+                  plasma-framework
+                  purpose
+                  sonnet
+                  qtdeclarative-5))
+                 ;qtwebengine-5)) ;; Optional for online dictionary
+    (synopsis "Add-ons to improve your Plasma experience")
+    (description
+     "This package provides multiple addons for the Plasma Desktop.")
+    (home-page "https://invent.kde.org/plasma/kdeplasma-addons")
+    (license license:lgpl2.0)))
+
+(define-public kgamma
+  (package
+    (name "kgamma")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "5-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "1c305bs50km7bsn0phz7yj4x2168sxwsw9zxbpcgw4q3r53c0ywz"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kauth
+                  kcoreaddons
+                  kconfig
+                  kconfigwidgets
+                  kdoctools
+                  ki18n))
+    (synopsis "Adjust monitor gamma settings")
+    (description
+     "This package provides a tool to adjust your monitor gamma settings.")
+    (home-page "https://invent.kde.org/plasma/kgamma5")
+    (license license:gpl2+)))
+
+(define-public khotkeys
+  (package
+    (name "khotkeys")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version "/"
+                                  name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0c9i4vxiiv90dpzsd2hjwavks87cvwplkj63751z8mazax6r95as"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kdbusaddons
+                  kdoctools
+                  kglobalaccel
+                  ki18n
+                  kcmutils
+                  kio
+                  ktextwidgets
+                  kxmlgui
+                  kdelibs4support
+                  plasma-workspace
+                  qtx11extras))
+    (synopsis "Trigger actions with the keyboard")
+    (description
+     "This package provides a way to trigger actions when certain keys
+are pressed.")
+    (home-page "https://invent.kde.org/plasma/khotkeys")
+    (license license:lgpl2.0)))
+
+(define-public kinfocenter
+  (package
+    (name "kinfocenter")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0zvki76yghkn158s7hb5g9drz7xaqxkmp2747404n2n0gmnmsdif"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (add-after 'unpack 'fix-systemsettings-symlink
+                          (lambda* (#:key inputs #:allow-other-keys)
+                            (substitute* "CMakeLists.txt"
+                              (("\\$\\{KDE_INSTALL_FULL_BINDIR\\}/systemsettings5")
+                               (search-input-file inputs
+                                                  "/bin/systemsettings5"))))))))
+    (native-inputs (list aha extra-cmake-modules kdoctools pkg-config))
+    ;; * vulkaninfo
+    ;; Wayland KCM
+    (inputs (list dmidecode
+                  ;; fwupdmgr ;; Packaged on master branch already
+                  kconfig
+                  kconfigwidgets
+                  kcoreaddons
+                  kirigami
+                  ki18n
+                  kcmutils
+                  kio
+                  kservice
+                  libusb
+                  kwidgetsaddons
+                  kdeclarative
+                  kpackage
+                  kwayland
+                  mesa-utils
+                  pciutils
+                  plasma-framework
+                  qtbase-5
+                  solid
+                  util-linux
+                  vulkan-tools
+                  wayland-utils
+                  xdpyinfo))
+    (propagated-inputs (list system-settings))
+    (home-page "https://invent.kde.org/plasma/kinfocenter")
+    (synopsis "View information about computer's hardware")
+    (description "This package provides tool to view information about
+computer's hardware.")
+    (license (list license:gpl2 license:gpl3))))
+
+(define-public kmenuedit
+  (package
+    (name "kmenuedit")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "0z85w7w207dnsinsz8yg6s408pwfy3l7wjkcsjpyg8aj8s9x6nl7"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules kdoctools))
+    (inputs (list ki18n
+                  kxmlgui
+                  kdbusaddons
+                  kiconthemes
+                  kio
+                  kitemviews
+                  sonnet
+                  kglobalaccel
+                  kwindowsystem))
+    (synopsis "Menu Editor for Plasma Workspaces")
+    (description "This package provides menu editor for Plasma Workspaces.")
+    (home-page "https://invent.kde.org/plasma/kmenuedit")
+    (license license:gpl2+)))
+
+(define-public kongress
+  (package
+    (name "kongress")
+    (version "22.09")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma-mobile/" version
+                                  "/kongress-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0pjp2s774sgw2dklqib8alm1a9fkixy3s92i2v8v00znx08zf2jz"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    ;; NOTE: Reporting bugs is linked to web browser, better not link it and let
+    ;; it reslove through xdg-open in the run time
+    (inputs (list kirigami
+                  kdbusaddons
+                  ki18n
+                  kcalendarcore
+                  kconfigwidgets
+                  kwindowsystem
+                  kcoreaddons
+                  kcontacts
+                  kitemmodels
+                  knotifications
+                  kxmlgui
+                  kiconthemes
+                  qtbase-5
+                  qtdeclarative-5
+                  qtquickcontrols2-5
+                  qtgraphicaleffects
+                  qtsvg-5))
+    (home-page "https://apps.kde.org/kongress/")
+    (synopsis "Companion application for conferences")
+    (description "This application provides list of upcoming conferences with
+the schedule and venue information.")
+    (license license:gpl3+)))
+
+(define-public kscreen
+  (package
+    (name "kscreen")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "0361202n0366jiyv61w06jikh2i4s1fzr6x3chmdykx4fgvbqj7s"))))
+    (build-system cmake-build-system)
+    (arguments
+     ;; TODO: All tests fail
+     (list #:tests? #f))
+    (native-inputs (list extra-cmake-modules qttools-5 pkg-config))
+    (inputs (list kconfig
+                  kdbusaddons
+                  kdeclarative
+                  kglobalaccel
+                  ki18n
+                  kwindowsystem
+                  kiconthemes
+                  kcoreaddons
+                  kcmutils
+                  kxmlgui
+                  libkscreen
+                  libxi
+                  plasma-wayland-protocols
+                  qtsensors
+                  qtbase-5
+                  qtx11extras
+                  xcb-util))
+    (propagated-inputs (list plasma-framework))
+    (home-page "https://invent.kde.org/plasma/kscreen")
+    (synopsis "Screen management software")
+    (description "This package provides the screen management software for
+KDE Plasma Workspaces.")
+    (license license:gpl2+)))
+
 (define-public ksshaskpass
   (package
     (name "ksshaskpass")
-    (version "5.25.3")
+    (version "5.25.5")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://kde/stable/plasma/" version
                                   "/ksshaskpass-" version ".tar.xz"))
               (sha256
                (base32
-                "0sfl77szvfq9c7v0gsv5nnf7h5kxigyy2z2p1cwmhm1pq4n606nk"))))
+                "0z8pp2mh4s98jh8jkf6r8v014gb6svapmp0m1npzw7zcmr6jvpn6"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools))
@@ -161,17 +706,99 @@ directly, you need to tell @code{ssh-add} about it.  @code{ssh-add} will then
 call it if it is not associated to a terminal.")
     (license license:gpl2+)))
 
+(define-public ksystemstats
+  (package
+    (name "ksystemstats")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "07xm6gn2k3vsl1pkrd2n9w8w8b7jq26h3cpslqha4ipw0by2mlqa"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (invoke "ctest" "-E" "ksystemstatstest")))))))
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list glib
+                  kcoreaddons
+                  kdbusaddons
+                  solid
+                  networkmanager-qt
+                  kiconthemes
+                  kio
+                  ki18n
+                  libksysguard
+                  libnl
+                  eudev
+                  `(,lm-sensors "lib")
+                  network-manager))
+    (synopsis "Plugin based system monitoring daemon")
+    (description
+     "This package provides a daemon that collects statistics about
+the running system.")
+    (home-page "https://invent.kde.org/plasma/ksystemstats")
+    (license (list license:gpl2 license:gpl3))))
+
+(define-public latte-dock
+  (package
+    (name "latte-dock")
+    (version "0.10.8")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/latte-dock/"
+                                  "latte-dock-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0ali9i0y0y1c5mdaps5ybhk4nqvzzs5jq27wj8rg8xxqjyfvbah0"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list qtbase-5
+                  qtdeclarative-5
+                  knotifications
+                  kwindowsystem
+                  kio
+                  plasma-framework
+                  kwayland
+                  kactivities
+                  kcrash
+                  kiconthemes
+                  knewstuff
+                  karchive
+                  kguiaddons
+                  kdbusaddons
+                  kglobalaccel
+                  kirigami
+                  ki18n
+                  kdeclarative
+                  kcoreaddons
+                  xcb-util
+                  qtx11extras
+                  libsm))
+    (synopsis "Latte is a dock based on plasma frameworks")
+    (description
+     "Latte is a dock based on plasma frameworks that provides
+an elegant and intuitive experience for your tasks and plasmoids.")
+    (home-page "https://github.com/KDE/latte-dock")
+    (license license:gpl2+)))
+
 (define-public layer-shell-qt
   (package
     (name "layer-shell-qt")
-    (version "5.25.3")
+    (version "5.25.5")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://kde/stable/plasma/" version
                                   "/layer-shell-qt-" version ".tar.xz"))
               (sha256
                (base32
-                "06rxqm4wh4mcszrwb2dbgpxj3dqfx0rccyyjp091lbsncqm1gib0"))))
+                "1mvhklq7n9hhjing704jr3ybq58ixwr9fdg3phnqhmdnqc2q3w0l"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config))
@@ -190,14 +817,14 @@ call it if it is not associated to a terminal.")
 (define-public kscreenlocker
   (package
     (name "kscreenlocker")
-    (version "5.25.3")
+    (version "5.25.5")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://kde/stable/plasma/" version
                                   "/kscreenlocker-" version ".tar.xz"))
               (sha256
                (base32
-                "1kii3r3j89avwyb00wrw80k5sj0q4wqgmy1q0yxfps9jk729k3wc"))))
+                "0mivx0l266310iy52qi94b6wi8w2a8nl7cjn5750x66dz81jl3yj"))))
     (build-system qt-build-system)
     (arguments
      `(#:tests? #f ;; TODO: make tests pass
@@ -252,27 +879,74 @@ call it if it is not associated to a terminal.")
      "@code{kscreenlocker} is a library for creating secure lock screens.")
     (license license:gpl2+)))
 
+(define-public ksysguard
+  (package
+    (name "ksysguard")
+    (version "5.22.0")
+    (source
+     (origin
+      (method url-fetch)
+      (uri (string-append "mirror://kde/stable/ksysguard/" version
+                          "/ksysguard-" version ".tar.xz"))
+      (sha256
+       (base32 "0bb2aj46v7ig0wn3ir68igryl2gblz2n75cddn8fwamvbx76570g"))))
+    (build-system qt-build-system)
+    ;; TODO: No tests found
+    (native-inputs
+     (list extra-cmake-modules kdoctools))
+    (inputs
+     (list kconfig
+       kcoreaddons
+       kdbusaddons
+       ki18n
+       kiconthemes
+       kinit
+       kio
+       kitemviews
+       knewstuff
+       knotifications
+       kwindowsystem
+       libksysguard
+       `(,lm-sensors "lib")
+       qtbase-5))
+    (home-page "https://www.kde.org/applications/system/ksysguard/")
+    (synopsis "Plasma process and performance monitor")
+    (description "KSysGuard is a program to monitor various elements of your
+system, or any other remote system with the KSysGuard daemon (ksysgardd)
+installed.")
+    (license license:gpl2+)))
+
 (define-public libkscreen
   (package
     (name "libkscreen")
-    (version "5.25.3")
+    (version "5.25.5")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/plasma/" version "/"
                            name "-" version ".tar.xz"))
        (sha256
-        (base32 "1mxkrk04wcyw4xbfiyxbp5iwnhqr10yk39zx5bbjd9zag0vdi7z5"))))
+        (base32 "17f2pbbkpmw3a32nsqlwd0x5xb71l6dzrh7ldwcqv46nvb54yhfa"))))
     (build-system qt-build-system)
+    (arguments
+     '(#:phases
+       (modify-phases %standard-phases
+         (replace 'check
+           (lambda* (#:key tests? #:allow-other-keys)
+             (when tests?
+               (setenv "HOME" (getcwd))
+               (setenv "QT_QPA_PLATFORM" "offscreen")
+               (setenv "WAYLAND_DISPLAY" "libkscreen-test-wayland-backend-0")
+               (invoke "ctest" "-E"
+                "(kscreen-testscreenconfig|kscreen-testqscreenbackend|kscreen-testkwaylandbackend|kscreen-testkwaylandconfig|kscreen-testkwaylanddpms)")))))))
     (native-inputs
      (list extra-cmake-modules
+           pkg-config
            ;; For testing.
            dbus))
     (inputs
      (list kwayland libxrandr plasma-wayland-protocols
            qtbase-5 qtwayland-5 wayland qtx11extras))
-    (arguments
-     '(#:tests? #f)) ; FIXME: 55% tests passed, 5 tests failed out of 11
     (home-page "https://community.kde.org/Solid/Projects/ScreenManagement")
     (synopsis "KDE's screen management software")
     (description "KScreen is the new screen management software for KDE Plasma
@@ -283,16 +957,17 @@ basic needs and easy to configure for those who want special setups.")
 (define-public libksysguard
   (package
     (name "libksysguard")
-    (version "5.25.3")
+    (version "5.25.5")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/plasma/" version
                            "/libksysguard-" version ".tar.xz"))
+       (patches (search-patches "libksysguard-qdiriterator-follow-symlinks.patch"))
        (sha256
-        (base32 "1mrrrxjvqmrnkjwafvqrd2hlvl9gr9y4hn7dv0gf70lp5bl06i89"))))
+        (base32 "1gqsjsdkp25abqqp4f6cv6ih199q9ad7q1a4lkhjgsh4h8jq1856"))))
     (native-inputs
-     (list extra-cmake-modules pkg-config qttools-5))
+     (list bash-minimal extra-cmake-modules pkg-config qttools-5))
     (inputs
      (list kauth
            kcompletion
@@ -323,13 +998,12 @@ basic needs and easy to configure for those who want special setups.")
            zlib))
     (build-system qt-build-system)
     (arguments
-     (list #:phases
-           #~(modify-phases %standard-phases
-               (replace 'check
-                 (lambda* (#:key tests? #:allow-other-keys)
-                   (when tests?
-                     ;; TODO: Fix this failing test-case
-                     (invoke "ctest" "-E" "processtest")))))))
+     (list #:phases #~(modify-phases %standard-phases
+                        (add-after 'unpack 'fix-test
+                          (lambda* _
+                            (substitute* "autotests/processtest.cpp"
+                              (("/bin/sh")
+                               (which "bash"))))))))
     (home-page "https://userbase.kde.org/KSysGuard")
     (synopsis "Network enabled task and system monitoring")
     (description "KSysGuard can obtain information on system load and
@@ -337,10 +1011,33 @@ manage running processes.  It obtains this information by interacting
 with a ksysguardd daemon, which may also run on a remote system.")
     (license license:gpl3+)))
 
+(define-public kwallet-pam
+  (package
+    (name "kwallet-pam")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "14w803lc3s2c0f4mqzzdhpfy5qnlz7wv00pbrc3v4k3zv381ci8n"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:tests? #f)) ;no tests
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list linux-pam kwallet libgcrypt socat))
+    (synopsis "PAM Integration with KWallet")
+    (description "Provide PAM Integration with KWallet to unlock KWallet when
+you login.")
+    (home-page "https://invent.kde.org/plasma/kwallet-pam")
+    (license (list license:lgpl2.1+))))
+
 (define-public kwayland-server
   (package
     (name "kwayland-server")
-    (version "5.24.4")
+    (version "5.24.6")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -348,7 +1045,7 @@ with a ksysguardd daemon, which may also run on a remote system.")
                     "/" name "-" version ".tar.xz"))
               (sha256
                (base32
-                "1279nqhy1qyz84dkn23rvzak8bg71hbrp09jlhv9mkjdb3bhnyfi"))))
+                "1wwgb1p177g6vvyf4l5jisigwvy5756ray1x355mlp7bi1pfs664"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config))
@@ -386,3 +1083,1444 @@ wayland-server API.")
                    ;; src/server/drm_fourcc.h carries the MIT license.
                    license:expat))))
 
+(define-public kwayland-integration
+  (package
+    (name "kwayland-integration")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "10xl7yrj519b9s5vq0hqqfz3vvg1fdwggw96snzm44iwycqbgss8"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (delete 'check)
+                        (add-after 'install 'check-after-install
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (setenv "HOME" (getcwd))
+                              (setenv "XDG_RUNTIME_DIR" (getcwd))
+                              (setenv "QT_QPA_PLATFORM" "offscreen")
+                              ;; https://bugs.gentoo.org/668872
+                              (invoke "ctest" "-E" "(idleTest-kwayland-test)"))))
+                        (add-before 'check-after-install 'check-setup
+                          (lambda* (#:key outputs #:allow-other-keys)
+                            (setenv "QT_PLUGIN_PATH"
+                                    (string-append #$output
+                                                   "/lib/qt5/plugins:"
+                                                   (getenv "QT_PLUGIN_PATH"))))))))
+    (native-inputs (list extra-cmake-modules wayland-protocols pkg-config))
+    (inputs (list kguiaddons
+                  kidletime
+                  kwindowsystem
+                  kwayland
+                  libxkbcommon
+                  wayland
+                  qtbase-5
+                  qtwayland-5))
+    (synopsis "KWayland runtime integration plugins")
+    (description "This package provides Wayland integration plugins for various
+KDE Frameworks components.")
+    (home-page "https://invent.kde.org/plasma/kwayland-integration")
+    (license (list license:lgpl2.1 license:lgpl3))))
+
+(define-public kwin
+  (package
+    (name "kwin")
+    (version "5.25.5")
+    (source (origin
+               (method url-fetch)
+               (uri (string-append "mirror://kde/stable/plasma/" version "/"
+                                   name "-" version ".tar.xz"))
+               (sha256
+                (base32
+                 "1dh7ydwxbb9r53p353d53gq7w9vmp7idvsr4s5ldxmah35436v2s"))))
+    (build-system qt-build-system)
+    (arguments
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'patch
+            (lambda* (#:key inputs #:allow-other-keys)
+              (substitute* '("src/plugins/kdecorations/aurorae/src/aurorae.cpp")
+                (("(^\\s*QDirIterator it.path, QDirIterator::Subdirectories)(\\);)"
+                  _ a b)
+                 (string-append a
+                                " | QDirIterator::FollowSymlinks" b)))
+              (substitute*
+                  '("autotests/integration/dont_crash_glxgears.cpp"
+                    "autotests/integration/debug_console_test.cpp"
+                    "autotests/integration/x11_window_test.cpp")
+                (("setProgram\\(QStringLiteral\\(\"glxgears\"\\)")
+                 (string-append
+                  "setProgram(QByteArrayLiteral(\"" (which "glxgears") "\")")))
+              (substitute*
+                  '("src/wayland/tests/renderingservertest.cpp"
+                    "src/wayland/tests/waylandservertest.cpp")
+                (("QByteArrayLiteral\\(\"Xwayland\"\\)")
+                 (string-append
+                  "QByteArrayLiteral(\"" (which "Xwayland") "\")")))
+              (substitute* '("src/xwayland/xwaylandlauncher.cpp")
+                (("(m_xwaylandProcess->setProgram.QStringLiteral..)(Xwayland)(...;)"
+                  _ a Xwayland b)
+                 (string-append a
+                                (which "Xwayland") b)))
+              (substitute* '("cmake/modules/Findhwdata.cmake")
+                (("/usr/share")
+                 (string-append #$hwdata:pnp "/share")))))
+          (add-after 'install 'add-symlinks
+            (lambda* (#:key outputs #:allow-other-keys)
+              (let ((kst5 (string-append #$output
+                                         "/share/kservicetypes5/")))
+                (symlink (string-append kst5 "kwineffect.desktop")
+                         (string-append kst5 "kwin-effect.desktop"))
+                (symlink (string-append kst5 "kwinscript.desktop")
+                         (string-append kst5 "kwin-script.desktop")))))
+          (replace 'check
+            (lambda* (#:key tests? #:allow-other-keys)
+              (when tests?
+                (setenv "XDG_RUNTIME_DIR" (getcwd))
+                (setenv "HOME" (getcwd))
+                (setenv "XDG_DATA_DIRS"
+                        (string-append #$output "/share:"
+                                       (getenv "XDG_DATA_DIRS")))
+                (setenv "QT_PLUGIN_PATH"
+                        (string-append #$output
+                                       "/lib/qt5/plugins:"
+                                       (getenv "QT_PLUGIN_PATH")))
+                (setenv "DISPLAY" ":1")
+                (system "Xvfb :1 &")
+                (sleep 5)
+                (invoke "ctest" "-E"
+                        "(kwayland-testXdgDecoration|kwin-testLockScreen|kwin-testPointerInput|kwin-testXdgShellWindow|kwin-testXdgShellWindow-waylandonly|kwin-testSceneOpenGLES|kwin-testSceneOpenGLES-waylandonly|kwin-testInputMethod|kwin-testInputMethod-waylandonly|kwin-testNightColor|kwin-testNightColor-waylandonly|kwin-testPlasmaWindow|kwin-testSceneQPainter|kwin-testLibinputDevice)")))))))
+    (native-inputs (list extra-cmake-modules
+                         dbus
+                         kdoctools
+                         mesa-utils
+                         pkg-config
+                         qttools-5
+                         wayland-protocols-next
+                         xorg-server-for-tests))
+    (inputs (list breeze
+                  eudev
+                  fontconfig
+                  freetype
+                  `(,hwdata "pnp")
+                  kactivities
+                  kcmutils
+                  kcompletion
+                  kconfig
+                  kconfigwidgets
+                  kcoreaddons
+                  kcrash
+                  kdbusaddons
+                  kdeclarative
+                  kdecoration
+                  kglobalaccel
+                  ki18n
+                  kiconthemes
+                  kidletime
+                  kio
+                  kirigami
+                  knewstuff
+                  knotifications
+                  kpackage
+                  krunner
+                  kscreenlocker
+                  ktextwidgets
+                  kwayland
+                  kwayland-server
+                  kwindowsystem
+                  kxmlgui
+                  libqaccessibilityclient
+                  lcms
+                  libcap
+                  libepoxy
+                  libglvnd ; For OpenGLES
+                  libinput
+                  libxkbcommon
+                  pipewire-0.3
+                  plasma-framework
+                  plasma-wayland-protocols
+                  qtbase-5
+                  qtdeclarative-5
+                  qtmultimedia-5
+                  qtwayland-5
+                  qtx11extras
+                  wayland
+                  xcb-util ;fails at build time without this
+                  xcb-util-cursor
+                  xcb-util-keysyms
+                  xcb-util-wm
+                  xcmsdb
+                  xinput ;XXX: Says disabled in configure phase
+                  xorg-server-xwayland
+                  zlib))
+    ;; Runtime-only dependency needed for mapping monitor hardware vendor IDs to full names
+    ;; * QtQuick.Controls-QMLModule, QML module 'QtQuick.Controls' is a runtime dependency.
+    ;; * org.kde.plasma.core-QMLModule, QML module 'org.kde.plasma.core' is a runtime dependency.
+    ;; * org.kde.plasma.components-QMLModule, QML module 'org.kde.plasma.components' is a runtime dependency.
+    (home-page "https://userbase.kde.org/KWin")
+    (synopsis "KDE Plasma Window Manager")
+    (description
+     "KWin is an easy to use, but flexible, composited Window Manager for
+Xorg windowing systems (Wayland, X11) on Linux.  Its primary usage is in
+conjunction with the KDE Plasma Desktop.")
+    (license license:gpl2+)))
+
+(define-public kwrited
+  (package
+    (name "kwrited")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "03gw3czdgyf35n6x79x416rk6f7w1ayzmy5pb65v9733nx1j34mh"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kcoreaddons ki18n kpty knotifications))
+    (home-page "https://invent.kde.org/plasma/kwrited")
+    (synopsis "System notification daemon")
+    (description
+     "This package provides a daemon that listens to system notifications.")
+    (license license:gpl2+)))
+
+(define-public lightly
+  (package
+    (name "lightly")
+    (version "0.4.1")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/Luwx/Lightly")
+                    (commit (string-append "v" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "0qkjzgjplgwczhk6959iah4ilvazpprv7yb809jy75kkp1jw8mwk"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kdecoration
+                  kcoreaddons
+                  kguiaddons
+                  kconfigwidgets
+                  kwindowsystem
+                  ki18n
+                  kiconthemes
+                  qtx11extras))
+    (home-page "https://github.com/Luwx/Lightly")
+    (synopsis "Modern style for Qt applications")
+    (description
+     "Lightly is a fork of the Breeze theme that aims to be visually modern
+and minimalistic.")
+    (license license:gpl2+)))
+
+(define-public milou
+  (package
+    (name "milou")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "0ijdbiq169sy47g0x22pj9x6abldpfxcnski4w1jh9hi9qz1rc25"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kcoreaddons
+                  ki18n
+                  kdeclarative
+                  kitemmodels
+                  kservice
+                  plasma-framework
+                  kwindowsystem
+                  krunner
+                  qtdeclarative-5))
+    (synopsis "Dedicated search application built on top of Baloo")
+    (description "This package provides a dedicated search application built
+on top of Baloo.")
+    (home-page "https://invent.kde.org/plasma/milou")
+    (license (list license:gpl2+))))
+
+(define-public oxygen-sounds
+  (package
+    (name "oxygen-sounds")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "04rn3ccqszznknvblz2i8r406m32hk4d3yzma4vzq93jfk57hdf1"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (home-page "https://community.kde.org/Frameworks")
+    (synopsis "Sounds for the KDE desktop")
+    (description "This package provides Oxygen sounds for the KDE desktop.")
+    (license license:lgpl3+)))
+
+(define-public plasma
+  (package
+    (name "plasma")
+    (version "5.25.5")
+    (source #f)
+    (build-system trivial-build-system)
+    (arguments
+     (list #:builder #~(begin
+                         (mkdir #$output))))
+    (propagated-inputs (list bluedevil
+                             breeze
+                             breeze-gtk
+                             discover
+                             drkonqi
+                             kactivitymanagerd
+                             kde-cli-tools
+                             ;; kde-gtk-config
+                             kdecoration
+                             kdeplasma-addons
+                             kgamma
+                             khotkeys
+                             kinfocenter
+                             kmenuedit
+                             kscreen
+                             kscreenlocker
+                             ksshaskpass
+                             ksystemstats
+                             kwallet-pam
+                             kwayland-integration
+                             kwin
+                             kwrited
+                             kinit
+                             layer-shell-qt
+                             libkscreen
+                             libksysguard
+                             milou
+                             ;; oxygen
+                             oxygen-sounds
+                             plasma-browser-integration
+                             plasma-desktop
+                             plasma-disks
+                             plasma-firewall
+                             plasma-integration
+                             plasma-nm
+                             plasma-pa
+                             plasma-systemmonitor
+                             ;; plasma-thunderbolt ;; waiting for bolt
+                             plasma-vault
+                             plasma-workspace
+                             plasma-workspace-wallpapers
+                             polkit-kde-agent
+                             powerdevil
+                             sddm
+                             system-settings
+                             xdg-desktop-portal-kde))
+    (synopsis "The KDE Plasma desktop environment")
+    (home-page "https://kde.org/plasma-desktop/")
+    (description
+     "KDE Plasma is an advanced graphical desktop system.")
+    (license license:gpl2+)))
+
+(define-public plasma-bigscreen
+  (package
+    (name "plasma-bigscreen")
+    (version "5.25.90")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/unstable/plasma/" version
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1445j8hzfvh2z91fa8nxrc0z576c67cq5fxcs19pmzpnjjli1ads"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (add-after 'unpack 'fix-startplasma
+                          (lambda* (#:key inputs #:allow-other-keys)
+                            (substitute* "bin/plasma-bigscreen-wayland.in"
+                              (("^startplasma-wayland")
+                               (search-input-file inputs
+                                                  "/bin/startplasma-wayland")))
+                              (substitute* "bin/plasma-bigscreen-x11"
+                                (("startplasma-x11")
+                                 (search-input-file inputs
+                                                    "/bin/startplasma-x11"))))))))
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kactivities
+                  kactivities-stats
+                  plasma-framework
+                  ki18n
+                  kirigami
+                  kdeclarative
+                  kcmutils
+                  knotifications
+                  kio
+                  kwayland
+                  kwindowsystem
+                  plasma-workspace
+                  qtbase-5
+                  qtmultimedia-5))
+    (home-page "https://invent.kde.org/plasma/plasma-bigscreen")
+    (synopsis "Plasma shell for TVs")
+    (description
+     "This package provides a big launcher designed for large screens.  It
+is controllable via voice or TV remote.")
+    (license license:gpl2+)))
+
+(define-public plasmatube
+  (package
+    (name "plasmatube")
+    (version "22.09")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma-mobile/"
+                                  version "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "00w9p5fcpv4s406lmcdcbrxf19sgkvf9yy8pfjmf1asvvvi8bpnk"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs
+     (list kconfig
+           kirigami
+           ki18n
+           qtbase-5
+           qtdeclarative-5
+           qtmultimedia-5
+           qtquickcontrols2-5
+           qtsvg-5
+           youtube-dl))
+    (home-page "https://apps.kde.org/plasmatube/")
+    (synopsis "Kirigami YouTube video player")
+    (description "This package provides YouTube video player based
+on QtMultimedia and @command{yt-dlp}.")
+    (license license:gpl3+)))
+
+(define-public plasma-active-window-control
+(let ((commit "0b1c091b5662fb21917064d7809b3be8b4a8be47")
+       (revision "1"))
+  (package
+    (name "plasma-active-window-control")
+    (version (git-version "1.7.3" revision commit))
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://invent.kde.org/plasma/plasma-active-window-control")
+                    (commit commit)))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "1lns1n7p6b64z7l3bn27hni100pp3k2whzzzg0adr4hiynycdix6"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs
+     (list kwindowsystem
+           libsm
+           plasma-framework
+           qtdeclarative-5
+           qtx11extras))
+    (home-page "https://invent.kde.org/plasma/plasma-active-window-control")
+    (synopsis "Plasma applet for controlling the currently active window")
+    (description "This package provides window control applet for the current
+active window on Plasma Desktop.")
+    (license (list license:gpl2 license:gpl3)))))
+
+(define-public plasma-browser-integration
+  (package
+    (name "plasma-browser-integration")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "18pbn5ic5l3m8i1y99yprpwd4x4746aq3abqn1f2cq5h2683h2ia"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config))
+    ;; TODO: Figure out how to integrate this package into web browsers
+    ;; CHROMIUM_EXTENSIONS_DIR - extension for chromium
+    ;; MOZILLA_DIR - extension for firefox
+    (inputs (list kio
+                  ki18n
+                  kcoreaddons
+                  kconfig
+                  kcrash
+                  kdbusaddons
+                  knotifications
+                  kitemmodels
+                  krunner
+                  kactivities
+                  purpose
+                  kfilemetadata
+                  kjobwidgets
+                  qtdeclarative-5))
+    (propagated-inputs (list plasma-workspace))
+    (home-page "https://invent.kde.org/plasma/plasma-browser-integration")
+    (synopsis "Integrate browsers into the Plasma Desktop")
+    (description
+     "This package aims to provide better integration of web browsers with
+the KDE Plasma 5 desktop.")
+    (license license:gpl3+)))
+
+(define-public plasma-desktop
+  (package
+    (name "plasma-desktop")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "05s1pkwr4xmkghp8jrwcyrvjm83n68ngmk2694055xcfgi0pxicg"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules
+                         dbus
+                         kdoctools
+                         intltool
+                         pkg-config
+                         qtsvg-5
+                         qttools-5))
+    (inputs (list packagekit-qt5
+                  signon-plugin-oauth2
+                  signond
+                  attica
+                  appstream-qt
+                  baloo
+                  breeze
+                  breeze-icons
+                  eudev
+                  fontconfig
+                  glib
+                  ibus
+                  kaccounts-integration
+                  kactivities
+                  kactivities-stats
+                  kauth
+                  karchive
+                  kcmutils
+                  kconfig
+                  kcoreaddons
+                  kcrash
+                  kdbusaddons
+                  kdeclarative
+                  kded
+                  kdesu
+                  kdelibs4support
+                  kglobalaccel
+                  kguiaddons
+                  kholidays
+                  ki18n
+                  kiconthemes
+                  kidletime
+                  kinit
+                  kio
+                  kitemmodels
+                  knewstuff
+                  knotifications
+                  knotifyconfig
+                  kpackage
+                  kpeople
+                  krunner
+                  kscreenlocker
+                  ktexteditor
+                  ktextwidgets
+                  kunitconversion
+                  kuserfeedback
+                  kwallet
+                  kwayland
+                  kwin
+                  layer-shell-qt
+                  libaccounts-qt
+                  libcanberra
+                  libkscreen
+                  libksysguard
+                  libqalculate
+                  gmp
+                  mpfr
+                  libsm
+                  libxi
+                  libxft
+                  libxkbcommon
+                  libxrender
+                  libxtst
+                  networkmanager-qt
+                  phonon
+                  pipewire-0.3
+                  plasma-framework
+                  plasma-wayland-protocols
+                  pulseaudio
+                  prison
+                  qqc2-desktop-style
+                  qtbase-5
+                  qtdeclarative-5
+                  qtquickcontrols2-5
+                  qtwayland
+                  qtx11extras
+                  wayland
+                  wayland-protocols
+                  xcb-util
+                  xcb-util-image
+                  xcb-util-keysyms
+                  xdg-user-dirs
+
+                  ;; These are needed for Xserver
+                  xf86-input-libinput
+                  xf86-input-evdev
+                  xorg-server
+                  xf86-input-synaptics
+                  xkeyboard-config
+                  libxkbfile
+                  libxcursor
+                  libxkbcommon))
+    (propagated-inputs (list iso-codes kirigami plasma-workspace))
+    (arguments
+     (list #:phases
+           #~(modify-phases %standard-phases
+               (add-after 'unpack 'fix-paths
+                 (lambda* (#:key inputs #:allow-other-keys)
+                   (substitute* "kcms/keyboard/iso_codes.h"
+                     (("\"/usr/share/xml/iso-codes\"")
+                      (string-append "\"" (search-input-directory
+                                           inputs "/share/xml/iso-codes")
+                                     "\"")))))
+               (add-after 'unpack 'patch-qml-import-path
+                 (lambda _
+                   (substitute*
+                       '("applets/pager/package/contents/ui/main.qml"
+                         "containments/desktop/package/contents/ui/FolderView.qml"
+                         "containments/desktop/package/contents/ui/main.qml"
+                         "containments/panel/contents/ui/main.qml")
+                     (("^import \"(utils|FolderTools|LayoutManager).js\" as "
+                       line mod)
+                      (string-append "import \"../code/" mod
+                                     ".js\" as ")))))
+               (replace 'check
+                 (lambda* (#:key tests? #:allow-other-keys)
+                   (when tests?
+                     (setenv "HOME" (getcwd))
+                     (setenv "XDG_RUNTIME_DIR" (getcwd))
+                     (setenv "XDG_CACHE_HOME" (getcwd))
+                     (setenv "QT_QPA_PLATFORM" "offscreen")
+                     (invoke "ctest" "-E" "foldermodeltest")))))))
+    (home-page "https://kde.org/plasma-desktop/")
+    (synopsis "Plasma for the Desktop")
+    (description
+     "Plasma Desktop offers a beautiful looking desktop that takes
+complete advantage of modern computing technology.  Through the use of visual
+effects and scalable graphics, the desktop experience is not only smooth but
+also pleasant to the eye.  The looks of Plasma Desktop not only provide
+beauty, they are also used to support and improve your computer
+activities effectively, without being distracting.")
+    (license license:gpl2+)))
+
+(define-public plasma-disks
+  (package
+    (name "plasma-disks")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "0vci2cf8vx2lclypys9rmvjb8haakv6ksrvqm5j28pazbq2kskvl"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kcoreaddons
+                  kdbusaddons
+                  knotifications
+                  ki18n
+                  solid
+                  kservice
+                  kio
+                  kauth
+                  kdeclarative
+                  smartmontools))
+    (synopsis "Monitors S.M.A.R.T. capable devices for imminent failure")
+    (description "This package provides interface to S.M.A.R.T. data of disks.")
+    (home-page "https://invent.kde.org/plasma/plasma-disks")
+    (license (list license:gpl2 license:gpl3))))
+
+(define-public plasma-firewall
+  (package
+    (name "plasma-firewall")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "0k3pc0dcsjr2hhh4hr8vhsvaddn66s6imm8skrr02icxqvljs6jh"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list iproute
+                  kcoreaddons
+                  kcmutils
+                  ki18n
+                  kdeclarative
+                  python
+                  qtdeclarative-5))
+    (synopsis "Control Panel for system firewall")
+    (description "This package provides interface to system firewall.")
+    (home-page "https://invent.kde.org/plasma/plasma-firewall")
+    (license (list license:gpl2 license:gpl3))))
+
+(define-public plasma-integration
+  (package
+    (name "plasma-integration")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "1pab56cg2zi8fcaar53lhhh98iw7l07f5lkymkqhsh8a5crfc3yr"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:tests? #f                  ;TODO: Failing tests
+           #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (setenv "HOME" (getcwd))
+                              (setenv "XDG_RUNTIME_DIR" (getcwd))
+                              (setenv "XDG_CACHE_HOME" (getcwd))
+                              (setenv "QT_QPA_PLATFORM" "offscreen")
+                              (invoke "ctest" "-E"
+                                      "(frameworkintegration-kdeplatformtheme_unittest|frameworkintegration-kfontsettingsdata_unittest|frameworkintegration-kfiledialog_unittest|qmltests|frameworkintegration-kfiledialogqml_unittest")))))))
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list breeze
+                  kconfig
+                  kio
+                  ki18n
+                  kwidgetsaddons
+                  kconfigwidgets
+                  kiconthemes
+                  knotifications
+                  libxcb
+                  libxcursor
+                  plasma-wayland-protocols
+                  qtdeclarative-5
+                  qtquickcontrols2-5
+                  qtwayland-5
+                  qtx11extras
+                  wayland))
+    (home-page "https://invent.kde.org/plasma/plasma-integration")
+    (synopsis
+     "Qt Platform Theme integration plugins for the Plasma workspaces")
+    (description
+     "This package provides a set of plugins responsible for better
+integration of Qt applications when running on a KDE Plasma workspace.")
+    (license license:lgpl2.0)))
+
+(define-public plasma-nano
+  (package
+    (name "plasma-nano")
+    (version "5.24.3")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "https://download.kde.org/stable/plasma/"
+                                  version "/plasma-nano-" version ".tar.xz"))
+              (sha256
+               (base32
+                "13jxhfi3c3dhg7zdyfqnsii661h1am0w9dsv82dalqvwr1mw28l5"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config qttools))
+    (inputs (list qtbase-5
+                  qtdeclarative-5
+                  plasma-framework
+                  kwindowsystem
+                  kwayland
+                  ki18n))
+    (home-page "https://plasma-mobile.org/")
+    (synopsis "Minimal Plasma Shell package")
+    (description
+     "This package provides a minimal implementation of Plasma Shell.")
+    (license license:lgpl2.0+)))
+
+(define-public plasma-nm
+  (package
+    (name "plasma-nm")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "036bx0qjrjanfxy8aiy6ab7rmm2h8l7wlkvlwhzw2hgl1w03xjps"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (invoke "ctest" "-E" "mobileproviderstest")))))))
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (home-page "https://invent.kde.org/plasma/plasma-nm")
+    (inputs (list kconfigwidgets
+                  kcompletion
+                  kcoreaddons
+                  kdeclarative
+                  kdbusaddons
+                  kio
+                  ki18n
+                  networkmanager-qt
+                  knotifications
+                  kirigami
+                  plasma-framework
+                  modemmanager-qt
+                  network-manager
+                  qca
+                  kservice
+                  solid
+                  prison
+                  kwallet
+                  kwidgetsaddons
+                  kwindowsystem
+                  openconnect
+                  qtdeclarative-5))
+    (synopsis "Plasma applet for managing network connections")
+    (description "This package provides Plasma applet for managing network
+connections.")
+    (license (list license:lgpl2.1 license:lgpl3))))
+
+(define-public plasma-mobile
+  (package
+    (name "plasma-mobile")
+    (version "5.24.3")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "https://download.kde.org/stable/plasma/"
+                                  version "/plasma-mobile-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1bwmy7xvd8wmh0snqqjh9jjgawib8ks2g30w48sqxwhplhf3da58"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (add-after 'install 'wrap-script
+                          (lambda* (#:key inputs outputs #:allow-other-keys)
+                            (wrap-program (string-append #$output
+                                                         "/bin/kwinwrapper")
+                                          `("PATH" ":" prefix
+                                            (,(string-append #$plasma-framework
+                                                             "/bin")))))))))
+    (native-inputs (list extra-cmake-modules pkg-config qttools))
+    (inputs (list bash-minimal
+                  kdeclarative
+                  ki18n
+                  kio
+                  knotifications
+                  kwayland
+                  kwin
+                  modemmanager-qt
+                  networkmanager-qt
+                  plasma-framework
+                  qtbase-5))
+    (home-page "https://plasma-mobile.org/")
+    (synopsis
+     "General UI components for Plasma Phone including shell, containment and applets")
+    (description "This package provides user-friendly, privacy-enabling and
+customizable platform for mobile devices.")
+    (license (list license:gpl3+ license:lgpl2.1+))))
+
+(define-public plasma-mobile-settings
+  (package
+    (name "plasma-mobile-settings")
+    (version "22.02")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma-mobile/" version
+                                  "/plasma-settings-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0b7lj3r9z9cz2vr0h15sqqxdaa7m07hsk8i2p8nf4a3yh02ywsxy"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list qtbase-5
+                  qtdeclarative-5
+                  kio
+                  modemmanager-qt
+                  networkmanager-qt
+                  ki18n
+                  plasma-framework
+                  kdeclarative
+                  kdbusaddons))
+    (home-page "https://plasma-mobile.org/")
+    (synopsis "Settings application for Plasma Mobile")
+    (description
+     "This package provides Settings application for Plasma Mobile.")
+    (license license:gpl2+)))
+
+(define-public plasma-mobile-sounds
+  (package
+    (name "plasma-mobile-sounds")
+    (version "0.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append
+                    "mirror://kde/stable/plasma-mobile-sounds/"
+                    version "/plasma-mobile-sounds-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1br6kzicrr45vgg0ciqczxlcid21n5lfjm6zc06rw86ys7fx7bpi"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (home-page "https://plasma-mobile.org/")
+    (synopsis "Sounds for Plasma Mobile devices")
+    (description "This package provides sound files for Plasma Mobile.")
+    (license (list license:cc0 license:cc-by4.0))))
+
+(define-public plasma-pa
+  (package
+    (name "plasma-pa")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/"
+                                  version "/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "0g06pm1isnzx4hv6380rjpyr22s4j5iw9083s71vnl4npx28npvb"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules kdoctools pkg-config))
+    (inputs (list glib
+                  kcoreaddons
+                  kdeclarative
+                  kglobalaccel
+                  knotifications
+                  kwindowsystem
+                  kirigami
+                  ki18n
+                  qtdeclarative-5))
+    (propagated-inputs (list libcanberra pulseaudio plasma-framework))
+    (home-page "https://invent.kde.org/plasma/plasma-pa")
+    (synopsis "Plasma applet for audio volume management using PulseAudio")
+    (description
+     "This package provides Plasma applet for audio volume management using
+PulseAudio.")
+    (license (list license:lgpl2.1 license:lgpl3))))
+
+(define-public plasma-pass
+  (package
+    (name "plasma-pass")
+    (version "1.2.0")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/" name "/"
+                                  name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "107pd6cnkd46px83pm3q7vbw10g5pd0qsw77jmr0c774k4xv1w01"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list ki18n kitemmodels kwindowsystem oath-toolkit qtdeclarative-5))
+    (propagated-inputs (list plasma-framework))
+    (home-page "https://invent.kde.org/plasma/plasma-pass")
+    (synopsis "Plasma applet for the Pass password manager")
+    (description
+     "This package provides a Plasma applet for the Pass password manager.")
+    (license license:lgpl2.1+)))
+
+(define-public plasma-phonebook
+  (package
+    (name "plasma-phonebook")
+    (version "0.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma-phonebook/"
+                                  version "/plasma-phonebook-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "13nnzdzpganlp319sc9dm9w5hsjhw4f3w8rb80q3nd8q6nyrpky8"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list kpeople
+                  kirigami
+                  kpeoplevcard
+                  kcoreaddons
+                  kcontacts
+                  qtbase-5
+                  qtdeclarative-5
+                  qtquickcontrols2-5
+                  qtsvg-5))
+    (home-page "https://plasma-mobile.org/")
+    (synopsis "Phonebook for Plasma Mobile devices")
+    (description "This package provides contacts application which allows
+adding, modifying and removing contacts.")
+    (license license:lgpl2.0+)))
+
+(define-public plasma-phone-components
+  (package
+    (name "plasma-phone-components")
+    (version "5.23.4")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/plasma-phone-components-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "0ml5pyi90nlmx5550sf3x9263f8mypj4jmdskzabzhnz44ck8vy9"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config qttools))
+    (inputs (list qtbase-5
+                  qtdeclarative
+                  kactivities
+                  kauth
+                  kbookmarks
+                  kwin
+                  kcodecs
+                  kcompletion
+                  kconfig
+                  kconfigwidgets
+                  kcoreaddons
+                  kdbusaddons
+                  kdeclarative
+                  ki18n
+                  kio
+                  kitemviews
+                  kjobwidgets
+                  knotifications
+                  kpackage
+                  kpeople
+                  kservice
+                  kwayland
+                  kwidgetsaddons
+                  kwindowsystem
+                  kxmlgui
+                  libphonenumber
+                  modemmanager-qt
+                  plasma-framework
+                  solid))
+    (home-page "https://plasma-mobile.org/")
+    (synopsis "Modules providing phone functionality for Plasma")
+    (description "This package provides user-friendly, privacy-enabling
+and customizable platform for mobile devices.")
+    (license (list license:gpl3+ license:lgpl2.1+))))
+
+(define-public plasma-redshift-control
+  (let ((commit "d9f38a5f0bcf030be16db1776166581c16e802cb")
+        (revision "1"))
+    (package
+      (name "plasma-redshift-control")
+      (version (git-version "0.1-pre" revision commit))
+      (home-page "https://invent.kde.org/plasma/plasma-redshift-control")
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference (url home-page) (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "1wadxhy6iljhikfw2rbj9dhwb86f2sgwyf62r7sfq6cszcpgp0xi"))))
+      (build-system qt-build-system)
+      (native-inputs (list extra-cmake-modules pkg-config))
+      (inputs (list kwindowsystem plasma-framework redshift))
+      (synopsis "Adjust color temperature")
+      (description
+       "This package provides color temperature control applet for the Plasma
+Desktop.")
+      (license (list license:lgpl2.1 license:lgpl3)))))
+
+(define-public plasma-vault
+  (package
+    (name "plasma-vault")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "15nf4myl6sry0930m8qiixpr1i8bh1g58cy2gf304h029vr2fn5j"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list kio
+                  ki18n
+                  kconfigwidgets
+                  kconfig
+                  kactivities
+                  kdbusaddons
+                  kiconthemes
+                  networkmanager-qt
+                  libksysguard
+                  plasma-framework
+                  qtdeclarative-5))
+    (home-page "https://invent.kde.org/plasma/plasma-vault")
+    (synopsis "Plasma applet and services for creating encrypted vaults")
+    (description "Provides Plasma applet and services for creating encrypted
+	vaults.")
+    (license (list license:gpl2 license:gpl3))))
+
+(define-public plasma-systemmonitor
+  (package
+    (name "plasma-systemmonitor")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version "/"
+                                  name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0rs3avhpmfapzha8dkir9ny60ba2m92bbfv4avsd85vz5kggg29h"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list ki18n
+                  kconfig
+                  kdeclarative
+                  kservice
+                  kiconthemes
+                  kglobalaccel
+                  kio
+                  kdbusaddons
+                  kirigami
+                  knewstuff
+                  ksystemstats
+                  kitemmodels
+                  libksysguard
+                  qtdeclarative-5
+                  qtquickcontrols2-5))
+    (synopsis "System sensors, process information and other system resources
+monitor")
+    (description "This package provides an interface for monitoring system
+sensors, process information and other system resources.")
+    (home-page "https://invent.kde.org/plasma/plasma-systemmonitor")
+    (license (list license:gpl2 license:gpl3))))
+
+(define-public plasma-welcome
+(let ((commit "dac7569078782a96f122782c15d34e51737d2b89") ; no tags
+      (revision "1"))
+  (package
+    (name "plasma-welcome")
+    (version (git-version "0.1-pre" revision commit))
+    (home-page "https://invent.kde.org/plasma/plasma-welcome")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference (url home-page) (commit commit)))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "1x7ra699r5a9kpa3isdnx6af4j6778kw2pmprnx4s8f1rwk2idhh"))))
+    (build-system qt-build-system)
+    (native-inputs
+     (list extra-cmake-modules pkg-config))
+    (inputs
+     (list kcoreaddons
+           kdbusaddons
+           kdeclarative
+           ki18n
+           kio
+           kirigami
+           knotifications
+           kservice
+           kwindowsystem
+           networkmanager-qt
+           plasma-framework
+           qtdeclarative-5
+           qtgraphicaleffects
+           qtsvg-5
+           qtquickcontrols2-5
+           system-settings))
+    (synopsis "Plasma welcome screen")
+    (description
+     "This package provides a wizard for Plasma to configure settings.")
+    (license (list license:gpl2 license:gpl3)))))
+
+(define-public plasma-workspace
+  (package
+    (name "plasma-workspace")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0pxwg3i07sipfchn4qkmlr6kcgqbhj2s10xq69wi32x1fc13jx5x"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules kdoctools pkg-config qtsvg-5
+                         qttools-5))
+    (inputs (list appmenu-gtk-module
+                  appstream-qt
+                  baloo
+                  breeze
+                  breeze-icons
+                  dbus
+                  fontconfig
+                  iso-codes
+                  kactivities
+                  kactivities-stats
+                  karchive
+                  kcmutils
+                  kcoreaddons
+                  kcrash
+                  kdbusaddons
+                  kdeclarative
+                  kded
+                  kdesu
+                  kglobalaccel
+                  kguiaddons
+                  kholidays
+                  ki18n
+                  kiconthemes
+                  kidletime
+                  kinit
+                  kio
+                  kio-extras
+                  kio-fuse
+                  kitemmodels
+                  kirigami
+                  knewstuff
+                  knotifications
+                  knotifyconfig
+                  kquickcharts
+                  kpackage
+                  kpeople
+                  krunner
+                  kscreenlocker
+                  ktexteditor
+                  ktextwidgets
+                  kunitconversion
+                  kuserfeedback
+                  kwallet
+                  kwayland
+                  kwin
+                  layer-shell-qt
+                  libkscreen
+                  libksysguard
+                  libqalculate
+                  gmp
+                  mpfr
+                  libsm
+                  libxft
+                  libxkbcommon
+                  libxrender
+                  libxtst
+                  networkmanager-qt
+                  phonon
+                  pipewire-0.3
+                  plasma-framework
+                  plasma-workspace-wallpapers
+                  plasma-wayland-protocols
+                  prison
+                  qtbase-5
+                  qtdeclarative-5
+                  qtquickcontrols2-5
+                  qtwayland-5
+                  qtgraphicaleffects
+                  qtx11extras
+                  wayland
+                  wayland-protocols-next
+                  xcb-util
+                  xcb-util-image
+                  xcb-util-keysyms
+                  xrdb
+                  xmessage
+                  xsetroot
+                  zlib))
+    (arguments
+     (list #:phases
+           #~(modify-phases %standard-phases
+               (add-after 'unpack 'patch-wallpaper
+                 (lambda* (#:key inputs #:allow-other-keys)
+                   (substitute* "sddm-theme/theme.conf.cmake"
+                     (("background=..KDE_INSTALL_FULL_WALLPAPERDIR.")
+                      (string-append "background="
+                                     #$(this-package-input "breeze")
+                                     "/share/wallpapers")))))
+               (add-after 'unpack 'patch-workspace-bins
+                 (lambda* (#:key inputs #:allow-other-keys)
+                   (let ((xmessage (search-input-file inputs "/bin/xmessage"))
+                         (xsetroot (search-input-file inputs "/bin/xsetroot"))
+                         (xrdb (search-input-file inputs "/bin/xrdb"))
+                         (kinit #$(this-package-input "kinit")))
+                     (substitute* "startkde/startplasma.cpp"
+                       (("xmessage") xmessage)
+                       (("xsetroot") xsetroot))
+                     (substitute* (list "kcms/fonts/fontinit.cpp"
+                                        "kcms/fonts/fonts.cpp"
+                                        "kcms/krdb/krdb.cpp")
+                       (("xrdb") xrdb))
+                     (substitute* "startkde/plasma-session/startup.cpp"
+                       (("CMAKE_INSTALL_FULL_LIBEXECDIR_KF5..")
+                        (string-append "\"" kinit
+                                       "/lib/libexec/kf5")))
+                     (substitute* (list
+                                   "startkde/startplasma-wayland.cpp"
+                                   "startkde/startplasma-x11.cpp")
+                       (("kdeinit5_shutdown")
+                        (string-append kinit "/bin/kdeinit5_shutdown"))))))
+               (delete 'check)
+               (add-after 'install 'check-after-install
+                 (lambda* (#:key tests? #:allow-other-keys)
+                   (when tests?
+                     (setenv "HOME" (getcwd))
+                     (setenv "XDG_RUNTIME_DIR" (getcwd))
+                     (setenv "XDG_CACHE_HOME" (getcwd))
+                     (setenv "QT_QPA_PLATFORM" "offscreen")
+                     (setenv "QT_PLUGIN_PATH"
+                             (string-append #$output
+                                            "/lib/qt5/plugins:"
+                                            (getenv "QT_PLUGIN_PATH")))
+                     (invoke "ctest" "-E"
+                             "(appstreamtest|lookandfeel-kcmTest|tst_triangleFilter|systemtraymodeltest|testdesktop| screenpooltest)")))))))
+    (home-page "https://invent.kde.org/plasma/plasma-workspace")
+    (synopsis "Plasma workspace components")
+    (description
+     "Workspaces provide support for KDE Plasma Widgets, integrated search,
+hardware management, and a high degree of customizability.")
+    (license (list license:gpl2 license:gpl3))))
+
+(define-public plasma-workspace-wallpapers
+  (package
+    (name "plasma-workspace-wallpapers")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0pdgg8h6zwyxf1pj241mg3hd94wh38bqxj68af5jfp10xrwkzcyr"))))
+    (build-system cmake-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (home-page "https://community.kde.org/Frameworks")
+    (synopsis "Oxygen wallpapers for the KDE desktop")
+    (description
+     "This package provides wallpapers for the KDE desktop.")
+    (license license:lgpl3+)))
+
+(define-public polkit-kde-agent
+  (package
+    (name "polkit-kde-agent")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version "/"
+                                  name "-1-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1qb9nxlkgcv0c30l2vqgf9xs9d220q5pg7ikpb6zjzvj4wsvlvwd"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list ki18n
+                  kwindowsystem
+                  kdbusaddons
+                  kwidgetsaddons
+                  kcoreaddons
+                  kcrash
+                  kiconthemes
+                  polkit-qt))
+    (synopsis "Polkit authentication UI for Plasma")
+    (description
+     "This package contains a daemon providing a Polkit authentication
+UI for Plasma")
+    (home-page "https://invent.kde.org/plasma/polkit-kde-agent-1")
+    (license license:gpl2+)))
+
+(define-public powerdevil
+  (package
+    (name "powerdevil")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0anisirn7z8aw442npdnk1csb5ghpzj2hx49gpw4l6ijk70b76pr"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules qttools-5 pkg-config))
+    (inputs (list bluez-qt
+                  glib
+                  kauth
+                  kactivities
+                  kscreen
+                  kidletime
+                  kconfig
+                  kdbusaddons
+                  solid
+                  ki18n
+                  kcrash
+                  knotifyconfig
+                  networkmanager-qt
+                  kio
+                  kwayland
+                  kglobalaccel
+                  kcrash
+                  knotifications
+                  kirigami
+                  libcap
+                  libkscreen
+                  network-manager
+                  plasma-workspace
+                  eudev
+                  qtx11extras))
+    (synopsis "Manage power consumption")
+    (description "This package provides the power consumption settings
+of a Plasma shell.")
+    (home-page "https://invent.kde.org/plasma/powerdevil")
+    (license license:gpl2+)))
+
+(define-public system-settings
+  (package
+    (name "system-settings")
+    (version "5.25.5")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma/" version
+                                  "/systemsettings-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0n7mf6ygi8fgn1m6pk2fadnqj1h58mxqni3h19xbi373wfypq5fl"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kauth
+                  kcrash
+                  kitemviews
+                  kitemmodels
+                  kcmutils
+                  ki18n
+                  kio
+                  kservice
+                  kiconthemes
+                  kwidgetsaddons
+                  kwindowsystem
+                  kxmlgui
+                  kdbusaddons
+                  kconfig
+                  kpackage
+                  kactivities
+                  kactivities-stats
+                  kguiaddons
+                  kirigami
+                  knotifications
+                  krunner
+                  plasma-workspace
+                  qtdeclarative-5))
+    (synopsis "Control center to configure Plasma Desktop")
+    (description "This package provides configuration UI for Plasma Desktop.")
+    (home-page "https://invent.kde.org/plasma/systemsettings")
+    (license license:gpl2+)))
diff --git a/gnu/packages/kde-utils.scm b/gnu/packages/kde-utils.scm
index b2295d184a..2742d6b846 100644
--- a/gnu/packages/kde-utils.scm
+++ b/gnu/packages/kde-utils.scm
@@ -22,22 +22,31 @@
 
 (define-module (gnu packages kde-utils)
   #:use-module (guix build-system qt)
+  #:use-module (guix gexp)
   #:use-module (guix download)
+  #:use-module (guix git-download)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (guix packages)
+  #:use-module (guix utils)
   #:use-module (gnu packages)
   #:use-module (gnu packages backup)
   #:use-module (gnu packages bash)
   #:use-module (gnu packages cmake)
   #:use-module (gnu packages compression)
+  #:use-module (gnu packages crypto)
+  #:use-module (gnu packages cups)
+  #:use-module (gnu packages glib) ; dbus for tests
   #:use-module (gnu packages gnome)
+  #:use-module (gnu packages gstreamer)
   #:use-module (gnu packages imagemagick)
+  #:use-module (gnu packages multiprecision)
   #:use-module (gnu packages pkg-config)
   #:use-module (gnu packages kde)
   #:use-module (gnu packages kde-frameworks)
   #:use-module (gnu packages kde-plasma)
   #:use-module (gnu packages qt)
   #:use-module (gnu packages samba)
+  #:use-module (gnu packages xdisorg)
   #:use-module (gnu packages xorg))
 
 (define-public ark
@@ -114,6 +123,216 @@ with support for multiple formats, including tar, gzip, bzip2, rar and zip, as
 well as CD-ROM images.")
     (license license:gpl2+)))
 
+(define-public atelier
+  (let ((commit "93d7d440c42f1e49a4933cbbce9f68d5e4ca725a") ; no releases
+        (revision "1"))
+    (package
+      (name "atelier")
+      (version (git-version "0.1-pre" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://invent.kde.org/utilities/atelier")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "00jccpwvksyp2vr3fjxajs8d9d30rspg4zj6rnj8dai96alp303k"))))
+      (build-system qt-build-system)
+      (native-inputs (list extra-cmake-modules pkg-config))
+      (inputs (list ki18n
+                    kxmlgui
+                    kconfigwidgets
+                    ktexteditor
+                    libatcore
+                    qt3d-5
+                    qtbase-5
+                    qtcharts
+                    qtdeclarative-5
+                    qtmultimedia-5
+                    qtserialport))
+      (home-page "https://atelier.kde.org")
+      (synopsis "Desktop interface to control 3D printers powered by AtCore")
+      (description "Atelier provides interface to control and manage your printer.
+@itemize
+@item Load and see your GCode File
+@item Real time graphic to monitor your bed and hotend temperatures
+@item You can log everything that comes and go from your printer
+@item Edit gcode file
+@end itemize")
+      (license license:gpl3+))))
+
+(define-public basket
+  (let ((commit "e23a8b3b1198d51f770523c7fb4652750810359a")
+        (revision "1"))
+    (package
+      (name "basket")
+      (version (git-version "2.49" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://invent.kde.org/utilities/basket")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "1i7hrrlwyzzh7mm9xc8hjix24rvy1b2cvvbkhxh9mmdbmphwdhhd"))))
+      (build-system qt-build-system)
+      (native-inputs (list extra-cmake-modules))
+      (inputs (list breeze-icons
+                    karchive
+                    kcompletion
+                    kconfig
+                    kconfigwidgets
+                    kcoreaddons
+                    kcrash
+                    kdbusaddons
+                    kdoctools
+                    kfilemetadata
+                    kglobalaccel
+                    kguiaddons
+                    ki18n
+                    kiconthemes
+                    kcmutils
+                    kio
+                    knotifications
+                    kparts
+                    kservice
+                    ktextwidgets
+                    kwidgetsaddons
+                    kwindowsystem
+                    kxmlgui
+                    phonon))
+      (home-page "https://invent.kde.org/utilities/basket")
+      (synopsis "Notes and to-dos organizer")
+      (description "This package provides simple note taking and to-do app.")
+      (license license:gpl2+))))
+
+(define-public fielding
+  (let ((commit "6b3c5d67b308e9e7e2043dc6072bfd265ec9f3e1")
+        ;; no releases yet
+        (revision "1"))
+    (package
+      (name "fielding")
+      (version (git-version "0.1-pre" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://invent.kde.org/utilities/fielding")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "1l16am7il7kprmy8irpzj04rb8wbfr84y49wp4i74hspp9xkfick"))))
+      (build-system qt-build-system)
+      (native-inputs (list extra-cmake-modules))
+      (inputs (list kirigami
+                    kcoreaddons
+                    kconfig
+                    ki18n
+                    kdbusaddons
+                    ksyntaxhighlighting
+                    qtdeclarative-5
+                    qtquickcontrols2-5
+                    qtsvg-5))
+      (home-page "https://invent.kde.org/utilities/fielding")
+      (synopsis "REST API testing tool")
+      (description
+       "This package provides a tool for testing REST APIs.")
+      (license license:lgpl2.1+))))
+
+(define-public filelight
+  (package
+    (name "filelight")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/filelight-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1fqgmpq5dznbn5lalx1j6dyynhylijrcqw3x9hrwxcqwr275h9iw"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kirigami
+                  kquickcharts
+                  kxmlgui
+                  kio
+                  ki18n
+                  kdeclarative
+                  qqc2-desktop-style
+                  qtgraphicaleffects
+                  qtquickcontrols2-5
+                  qtsvg-5))
+    (home-page "https://apps.kde.org/filelight/")
+    (synopsis "Visualize the disk usage")
+    (description "Filelight is an application to visualize the disk usage on
+your computer.")
+    (license license:lgpl2.1+)))
+
+(define-public francis
+  (let ((commit "d2c762ad94170430a667ee57f81ec9dbe498642c") ; no release yet
+        (revision "1"))
+    (package
+      (name "francis")
+      (version (git-version "0.1-pre" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://invent.kde.org/utilities/francis")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "15bk5iq127mp34n9fzq4d5r3qss3ihk93lqy86z2q3lgwid26s0h"))))
+      (build-system qt-build-system)
+      (native-inputs (list extra-cmake-modules))
+      (inputs (list kirigami
+                    kcoreaddons
+                    kconfig
+                    ki18n
+                    kdbusaddons
+                    knotifications
+                    qtdeclarative-5
+                    qtgraphicaleffects
+                    qtquickcontrols2-5
+                    qtsvg-5))
+      (home-page "https://invent.kde.org/utilities/francis")
+      (synopsis "Track your time")
+      (description "This package provides time tracking.")
+      (license license:lgpl2.1+))))
+
+(define-public isoimagewriter
+  (let ((commit "bd1ef4f0ce179fa874b102689022ebda3e7b4c16")
+        (revision "1"))
+    (package
+      (name "isoimagewriter")
+      (version (git-version "0.8" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://invent.kde.org/utilities/isoimagewriter")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "0dha2y4kmyppi6c0g0hclp53fjj963vq27q7azznpl0bz6zb4042"))))
+      (build-system qt-build-system)
+      (native-inputs (list extra-cmake-modules))
+      (inputs (list kauth
+                    karchive
+                    kcoreaddons
+                    ki18n
+                    kiconthemes
+                    kcrash
+                    solid
+                    kwidgetsaddons))
+      (home-page "https://invent.kde.org/utilities/isoimagewriter")
+      (synopsis "Write hybrid ISO files onto USB disks")
+      (description
+       "This package provides a tool to write ISO files to USB disks.")
+      (license license:gpl3+))))
+
 (define-public kate
   (package
     (name "kate")
@@ -180,6 +399,380 @@ Kate's features include:
     (license ;; GPL for programs, LGPL for libraries
      (list license:gpl2+ license:lgpl2.0))))
 
+(define-public kdebugsettings
+  (package
+    (name "kdebugsettings")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/kdebugsettings-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "0l9q7cmzc93zz2zc5ncq3q7q6jil6ai36n2vh70s2wsi8b0gsms8"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kcoreaddons
+                  kconfig
+                  kdbusaddons
+                  ki18n
+                  kwidgetsaddons
+                  kitemviews
+                  kcompletion))
+    (home-page "https://invent.kde.org/utilities/kdebugsettings")
+    (synopsis "Choose which QLoggingCategory are displayed")
+    (description
+     "This package allows to select which QLoggingCategory are displayed.")
+    (license license:lgpl2.0+)))
+
+(define-public kbackup
+  (package
+    (name "kbackup")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/kbackup-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0c0zdk00j9qssjdb5dg5hwc5mx7h5kvriyszia2xizqjq2m53c3k"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kguiaddons
+                  knotifications
+                  ki18n
+                  kio
+                  kxmlgui
+                  kiconthemes
+                  karchive
+                  kwidgetsaddons
+                  shared-mime-info))
+    (home-page "https://apps.kde.org/kbackup/")
+    (synopsis "Backup program with an easy-to-use interface")
+    (description
+     "This package provides tool to backup your data.
+@itemize
+@item profile for directories and files to be included or excluded from the
+backup
+@item The backup target can be either a locally mounted device like a ZIP
+drive, USB stick, etc
+@item Running automated backups without using a graphical user interface
+@end itemize")
+    (license license:gpl2+)))
+
+(define-public kcalc
+  (package
+    (name "kcalc")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/kcalc-" version ".tar.xz"))
+              (sha256
+               (base32
+                "01rn6qy40q4b90i5mysrygkqh5fzq885dgcd11l6r8s59ijjcjlk"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules kdoctools))
+    (inputs (list gmp
+                  kcoreaddons
+                  kcrash
+                  kconfig
+                  kconfigwidgets
+                  kguiaddons
+                  ki18n
+                  knotifications
+                  kxmlgui
+                  mpfr))
+    (home-page "https://apps.kde.org/kcalc/")
+    (synopsis "Scientific calculator")
+    (description
+     "This package provides a scientific calculator.")
+    (license license:gpl2+)))
+
+(define-public kcharselect
+  (package
+    (name "kcharselect")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/kcharselect-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "1gs9jkq76dkhjgjqpl5dcsx0l2qi6i0pk122y1qmwgyd6f8af35b"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kbookmarks kcoreaddons kcrash ki18n kwidgetsaddons kxmlgui))
+    (home-page "https://apps.kde.org/kcharselect/")
+    (synopsis "Select and copy special characters from installed fonts")
+    (description
+     "This package provides a tool to display various information
+about the selected character.  This includes not only the Unicode character
+name, but also aliases, general notes and cross references to similar
+characters.")
+    (license license:gpl2+)))
+
+(define-public kdialog
+  (package
+    (name "kdialog")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/kdialog-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1lqzhfn5g16qr6ada9i0i3kshna1zxp1y20ylwmmsa82bgmyblhx"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules kdoctools))
+    (inputs (list ktextwidgets
+                  knotifications
+                  kguiaddons
+                  kiconthemes
+                  kwindowsystem
+                  kio
+                  kdbusaddons))
+    (home-page "https://invent.kde.org/utilities/kdialog")
+    (synopsis "Show dialog boxes from shell scripts")
+    (description "This package provides tool to show nice dialog boxes from
+shell scripts.")
+    (license license:gpl2+)))
+
+(define-public keurocalc
+  (let ((commit "a760d8a7e58b36eb72d15e847f96599c93785194") ; just one release
+        (revision "1"))
+    (package
+      (name "keurocalc")
+      (version (git-version "1.3.0" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://invent.kde.org/utilities/keurocalc")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "0gh5vwl38hwf1405c980j1fj06g5c52am140lf4mxhrjvnmry7kd"))))
+      (build-system qt-build-system)
+      (native-inputs (list extra-cmake-modules kdoctools))
+      (inputs (list kconfig
+                    kconfigwidgets
+                    kcoreaddons
+                    ki18n
+                    kio
+                    kwidgetsaddons
+                    kxmlgui))
+      (home-page "https://invent.kde.org/utilities/keurocalc")
+      (synopsis "Currency conversion tool")
+      (description "This package provides a utility to handle currency
+conversions between European currencies.")
+      (license license:gpl2+))))
+
+(define-public keysmith
+  (package
+    (name "keysmith")
+    (version "22.09")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/plasma-mobile/"
+                                  (version-major+minor version) "/keysmith-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "0w3vvmp9rn6ahly2fm9n6f4glfr7d84bfvj33mrs5pn7n99h7jgy"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules pkg-config))
+    (inputs (list kdbusaddons
+                  kirigami
+                  ki18n
+                  kwindowsystem
+                  libsodium
+                  qtdeclarative-5
+                  qtgraphicaleffects
+                  qtquickcontrols2-5
+                  qtsvg-5))
+    (home-page "https://invent.kde.org/utilities/keysmith")
+    (synopsis "OTP client for Plasma Mobile and Desktop")
+    (description
+     "This package provides OTP client for Plasma Mobile and Desktop
+with support for QR scanning.")
+    (license license:gpl3+)))
+
+(define-public kfind
+  (package
+    (name "kfind")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/kfind-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0py6ygnj7qxbwrldf2a3hqc1cqd5yvyfi1l0nji0hwn8lvidnjhc"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules kdoctools))
+    (inputs (list karchive
+                  kcoreaddons
+                  kfilemetadata
+                  ki18n
+                  kio
+                  kwidgetsaddons))
+    (home-page "https://apps.kde.org/kfind/")
+    (synopsis "File search utility")
+    (description
+     "This package provides a file search utility for KDE.")
+    (license license:gpl2+)))
+
+(define-public kirogi
+  (let ((commit "73b009f1fc5ac159c2faba720b302c704f89a806") ; no releases yet
+        (revision "1"))
+    (package
+      (name "kirogi")
+      (version (git-version "0.1-pre" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://invent.kde.org/utilities/kirogi")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "1gncfnwadh11ipynfcrsh1vnk2g02c7scd5wanphi8i95jzak9jd"))))
+      (build-system qt-build-system)
+      (arguments
+       (list #:phases #~(modify-phases %standard-phases
+                          (add-after 'unpack 'fix-gstreamer
+                            (lambda* _
+                              (substitute* "CMakeLists.txt"
+                                (("gstreamer-video-1.0")
+                                 "")))))))
+      (native-inputs (list extra-cmake-modules pkg-config))
+      (inputs (list kconfigwidgets
+                    kcoreaddons
+                    ki18n
+                    kirigami
+                    kcrash
+                    kdnssd
+                    qtquickcontrols2-5
+                    qtgraphicaleffects
+                    qtdeclarative-5
+                    qtgamepad
+                    qtlocation))
+      (propagated-inputs (list gstreamer))
+      (home-page "https://apps.kde.org/kirogi/")
+      (synopsis "Ground control application for drones")
+      (description "Kirogi is a ground control application for drones.
+@itemize
+@item Direct flight controls
+@item Fly by touch on a Navigation Map
+@item Trigger vehicle actions (e.g. flips, trim)
+@item Gamepad/joypad support
+@item Live video
+@item Take photo and record video
+@item Configure flight parameters (speed, altitude limits)
+@item Support for Parrot (Anafi, Bebop 2) and Ryze Tello drones
+@end itemize")
+      (license ;GPL for programs, LGPL for libraries
+               (list license:gpl2+ license:lgpl2.0)))))
+
+(define-public kontrast
+  (package
+    (name "kontrast")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/kontrast-" version ".tar.xz"))
+              (sha256
+               (base32
+                "03y3y5p29zx4nmqi7hp3abxq2n2bgwbz2knhn9vhl3im3ghp7lmp"))))
+    (build-system qt-build-system)
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kirigami
+                  ki18n
+                  kcoreaddons
+                  qtdeclarative-5
+                  qtgraphicaleffects
+                  qtquickcontrols2-5
+                  qtsvg-5))
+    (home-page "https://apps.kde.org/kontrast/")
+    (synopsis "Color contrast checker")
+    (description
+     "Kontrast is a color contrast checker and tells you if your color
+combinations are distinct enough to be readable and accessible.")
+    (license license:gpl3+)))
+
+(define-public libatcore
+  (let ((commit "0de6393ed3e721537dec50b0ad174d83f1207eb6")
+        (revision "1"))
+    (package
+      (name "libatcore")
+      (version (git-version "1.0.0" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                      (url "https://invent.kde.org/libraries/atcore")
+                      (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "1830r6ylpn3l7y2frl8cih5cpjgbkfrib9jq7jklf8aszhlsihf2"))))
+      (build-system qt-build-system)
+      (native-inputs (list extra-cmake-modules))
+      (inputs (list qtcharts qtdeclarative-5 qtserialport))
+      (home-page "https://invent.kde.org/libraries/atcore")
+      (synopsis "Library for connection and management of 3D printers")
+      (description
+       "This package provides a API to manage the serial connection between
+the computer and 3D Printers.")
+      (license (list license:lgpl2.1 license:lgpl3)))))
+
+(define-public wacomtablet
+  (package
+    (name "wacomtablet")
+    (version "3.2.0")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/"
+                                  name "/" version "/"
+                                  name "-" version ".tar.xz"))
+              (patches (search-patches
+                        "wacomtablet-add-missing-includes.patch"
+                        "wacomtablet-qt5.15.patch"))
+              (sha256
+               (base32
+                "197pwpl87gqlnza36bp68jvw8ww25znk08acmi8bpz7n84xfc368"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (invoke "dbus-launch" "ctest" "-E"
+                               "(Test.KDED.DBusTabletService|Test.KDED.TabletHandler|Test.KDED.XInputAdaptor|Test.KDED.XsetWacomAdaptor)")))))))
+    (native-inputs (list dbus extra-cmake-modules kdoctools pkg-config))
+    (inputs (list kcoreaddons
+                  ki18n
+                  kglobalaccel
+                  kconfig
+                  kxmlgui
+                  kwidgetsaddons
+                  kwindowsystem
+                  knotifications
+                  kdbusaddons
+                  qtx11extras
+                  qtdeclarative-5
+                  libwacom
+                  xf86-input-wacom
+                  libxi))
+    (propagated-inputs (list plasma-framework))
+    (home-page "https://invent.kde.org/system/wacomtablet")
+    (synopsis "KDE GUI for the Wacom Linux Drivers")
+    (description "Provides KDE GUI for the Wacom Linux Drivers.")
+    (license license:gpl2+)))
+
 (define-public kmag
   (package
     (name "kmag")
@@ -456,6 +1049,41 @@ redone.")
     (license ;; GPL for programs, LGPL for libraries, FDL for documentation
      (list license:gpl2+ license:lgpl2.0+ license:fdl1.2+))))
 
+(define-public print-manager
+  (package
+    (name "print-manager")
+    (version "22.08.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (string-append "mirror://kde/stable/release-service/" version
+                           "/src/print-manager-" version ".tar.xz"))
+       (sha256
+        (base32 "1abwj1ccm70adzx07ykqjlb4f6y55k2rv1j861dl0822187vl799"))))
+    (build-system qt-build-system)
+    (native-inputs
+     (list extra-cmake-modules))
+    (inputs
+     (list cups
+           kcmutils
+           kconfig
+           kconfigwidgets
+           kcoreaddons
+           kdbusaddons
+           kiconthemes
+           ki18n
+           kio
+           knotifications
+           kwidgetsaddons
+           kwindowsystem
+           plasma-framework
+           qtdeclarative-5))
+    (home-page "https://invent.kde.org/utilities/print-manager")
+    (synopsis "Manage print jobs and printers")
+    (description
+     "This package provides printing management for KDE.")
+    (license license:gpl2+)))
+
 (define-public rsibreak
   (package
     (name "rsibreak")
diff --git a/gnu/packages/kde.scm b/gnu/packages/kde.scm
index f4d36c0f3a..1c1c371fb8 100644
--- a/gnu/packages/kde.scm
+++ b/gnu/packages/kde.scm
@@ -68,6 +68,7 @@
   #:use-module (gnu packages ghostscript)
   #:use-module (gnu packages gimp)
   #:use-module (gnu packages gl)
+  #:use-module (gnu packages glib)
   #:use-module (gnu packages gnome)
   #:use-module (gnu packages gps)
   #:use-module (gnu packages graphics)
@@ -99,14 +100,14 @@
 (define-public baloo-widgets
   (package
     (name "baloo-widgets")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/baloo-widgets-" version ".tar.xz"))
        (sha256
-        (base32 "0084bnrlbdypdwzxi9gfxcywhyjd1z2cmh7p6gv0zhc9f7h6ffnp"))))
+        (base32 "02p4v8g4syk908mg7f0l5fpqn7ddsxqji1n8jqghsdkkdsvry7mn"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -123,14 +124,14 @@ This package contains GUI widgets for baloo.")
 (define-public grantleetheme
   (package
     (name "grantleetheme")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/grantleetheme-" version ".tar.xz"))
        (sha256
-        (base32 "50c6s1g3vp5sdhpiciz1j6rsryld7hcc6lvmxdlsvms2bbcmnj7l"))))
+        (base32 "01ls16x6ngi43lcwffav9qig3afakrs04v4wvyfb8lm7sd65hgf9"))))
     (build-system qt-build-system)
     (arguments `(#:tests? #f))  ; unexpected error in the test suite.
     (native-inputs
@@ -151,14 +152,14 @@ This package contains GUI widgets for baloo.")
 (define-public akregator
   (package
     (name "akregator")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/akregator-" version ".tar.xz"))
        (sha256
-        (base32 "08n713271i7ifnbrgwrqmxvcpvj45wfqjiidw8zf9rpwxg2m2m9g"))))
+        (base32 "01rgyl2hwjprq4z5yjc99j6jk9vrhjy608ha72j470pw6g47ac5s"))))
     (build-system qt-build-system)
     (arguments
      `(#:phases
@@ -195,7 +196,7 @@ This package contains GUI widgets for baloo.")
            kontactinterface
            kpimcommon
            kpimtextedit
-           kqtquickcharts
+           kquickcharts
            ktexteditor
            kuserfeedback
            libkdepim
@@ -220,7 +221,7 @@ browser for easy news reading.")
 (define-public kdenlive
   (package
     (name "kdenlive")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method git-fetch)
@@ -229,7 +230,7 @@ browser for easy news reading.")
              (commit (string-append "v" version))))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "0v545kd5rm5isy4cx21fp3pi49mvsv1r1ahp0jhim8s6b7ghrh64"))))
+        (base32 "0xnasi8s8zxh2s4vnn51pc8ni58q8pk70bwh9dfxp1wdmpv3zsrx"))))
     (build-system qt-build-system)
     (arguments
      ;; XXX: there is a single test that spawns other tests and
@@ -304,14 +305,14 @@ projects.")
 (define-public kdevelop
   (package
     (name "kdevelop")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
       (origin
         (method url-fetch)
         (uri (string-append "mirror://kde/stable/release-service/" version
                             "/src/kdevelop-" version ".tar.xz"))
         (sha256
-         (base32 "03dwllxy96sy20kdsc3sll0n6bhh6gdmpjl821flsxv0jb5naplv"))))
+         (base32 "14a80z4sahxyzssrz605zp7ah5xdjbc22ccv0vwcnhr5lzr76v31"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config shared-mime-info qttools-5))
@@ -443,6 +444,102 @@ a module for implementing ODF Gantt charts, which are bar charts that
 illustrate project schedules.")
     (license license:gpl2+)))
 
+(define-public kio-extras
+  (package
+    (name "kio-extras")
+    (version "22.08.0")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/" name "-"
+                                  version ".tar.xz"))
+              (sha256
+               (base32
+                "0gzna2ps2qd2js28c97kjpcbah7zz8n4s4932faggc2nz5z5wnyn"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (setenv "HOME" (getcwd))
+                              (setenv "TMPDIR" (getcwd))
+                              (invoke "ctest" "-E" "testkioarchive")))))))
+    (native-inputs (list extra-cmake-modules dbus kdoctools qttools-5))
+    (inputs (list karchive
+                  kconfig
+                  kconfigwidgets
+                  kcoreaddons
+                  kdbusaddons
+                  ki18n
+                  kdnssd
+                  kio
+                  solid
+                  kbookmarks
+                  kguiaddons
+                  ksyntaxhighlighting
+                  qtbase-5
+                  qtsvg-5))
+    (home-page "https://community.kde.org/Frameworks")
+    (synopsis "Additional components to increase the functionality of KIO")
+    (description
+     "This package provides additional components to increase
+the functionality of the KDE resource and network access abstractions.")
+    (license license:lgpl2.0+)))
+
+(define-public kio-fuse
+  (package
+    (name "kio-fuse")
+    (version "5.0.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/" name "/" version "/"
+                                  name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "1pb62h45c06dq3rml91xbf8j5y2c1l8z8j8lycchxrlgys5rlrv6"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (replace 'check
+                          (lambda* (#:key tests? #:allow-other-keys)
+                            (when tests?
+                              (setenv "HOME" (getcwd))
+                              (setenv "XDG_RUNTIME_DIR" (getcwd))
+                              (setenv "QT_QPA_PLATFORM" "offscreen")
+                              (invoke "dbus-launch" "ctest" "-E"
+                               "(fileopstest-cache|fileopstest-filejob)")))))))
+    (native-inputs (list dbus extra-cmake-modules pkg-config))
+    (inputs (list fuse-3 kio kcoreaddons qtbase-5))
+    (home-page "https://community.kde.org/Frameworks")
+    (synopsis "FUSE Interface for KIO")
+    (description "This package provides FUSE Interface for KIO.")
+    (license license:lgpl2.1+)))
+
+(define-public kirigami-addons
+  (package
+    (name "kirigami-addons")
+    (version "0.3")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append
+                    "https://invent.kde.org/libraries/kirigami-addons/-/archive/v"
+                    version "/kirigami-addons-v" version ".tar.gz"))
+              (sha256
+               (base32
+                "1zr8dpc7bzw6g3y0jaxsr2lqlxqwlcphchpk8iah6g1f3n9fq73r"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:tests? #f)) ; failing test
+    (native-inputs (list extra-cmake-modules))
+    (inputs (list kirigami ki18n qtdeclarative-5 qtquickcontrols2-5))
+    (home-page "https://invent.kde.org/libraries/kirigami-addons")
+    (synopsis "Add-ons for the Kirigami framework")
+    (description
+     "This package provides Kirigami components usable by both touch
+and desktop experiences.")
+    (license license:lgpl2.0+)))
+
 (define-public kseexpr
   (package
     (name "kseexpr")
@@ -581,17 +678,52 @@ the generated @file{massif.out.%pid} in the visualizer.  Gzip or Bzip2
 compressed massif files can also be opened transparently.")
     (license license:gpl2+)))
 
+(define-public libqaccessibilityclient
+  (package
+    (name "libqaccessibilityclient")
+    (version "0.4.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/" name
+                                  "/libqaccessibilityclient-" version
+                                  ".tar.xz"))
+              (sha256
+               (base32
+                "0a9lv2jb5gyqxvrkl5xl09gjnlp05b5yfzfb0wmaxz0l8d7qnxhw"))))
+    (build-system cmake-build-system)
+    (arguments
+     `(#:tests? #f ;TODO: Failing tests
+       #:phases (modify-phases %standard-phases
+                  (replace 'check
+                    (lambda* (#:key tests? #:allow-other-keys)
+                      (when tests?
+                         ;
+                        ;; make Qt render "offscreen", required for tests
+                        (setenv "QT_QPA_PLATFORM" "offscreen")
+                        ;; For missing '/etc/machine-id'
+                        (setenv "DBUS_FATAL_WARNINGS" "0")
+                        (setenv "HOME"
+                                (getcwd))
+                        (invoke "dbus-launch" "ctest")))))))
+    (native-inputs (list dbus extra-cmake-modules))
+    (inputs (list qtbase-5))
+    (home-page "https://invent.kde.org/libraries/libqaccessibilityclient")
+    (synopsis "Helper library to make writing accessibility tools easier")
+    (description "This package provides library that is used when writing
+accessibility clients such as screen readers.")
+    (license license:lgpl2.1+)))
+
 (define-public libkomparediff2
   (package
     (name "libkomparediff2")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
       (origin
         (method url-fetch)
         (uri (string-append "mirror://kde/stable/release-service/" version
                             "/src/libkomparediff2-" version ".tar.xz"))
         (sha256
-         (base32 "1vaxbx7c6r7skh3452blxyrngfcsdyjmmvcg6j2wcsn04m01mw8k"))))
+         (base32 "0hjxxhfv0ds05l821avq787sfdy0afr595xx266c20x8fxgm6kv9"))))
     (native-inputs
      (list extra-cmake-modules pkg-config))
     (inputs
@@ -636,10 +768,70 @@ including SSL/TLS, X.509 certificates, SASL, OpenPGP, S/MIME CMS, and smart
 cards.")
     (license license:lgpl2.1+)))
 
+(define-public kopeninghours
+  (package
+    (name "kopeninghours")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "03hslgx4zgg7gsnz2xhx4wnchvqfc5n8c6ihgwz3972fkxsjfdvq"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list #:phases '(modify-phases %standard-phases
+                       (replace 'check
+                         (lambda* (#:key tests? #:allow-other-keys)
+                           (when tests?
+                             (setenv "QT_QPA_PLATFORM" "offscreen")
+                             (invoke "ctest" "-E"
+                                     "(evaluatetest|iterationtest)")))))))
+    (native-inputs (list bison extra-cmake-modules flex))
+    (inputs (list boost
+                  kholidays
+                  ki18n
+                  osmctools
+                  qtbase-5
+                  qtdeclarative-5))
+    (home-page "https://invent.kde.org/libraries/kopeninghours")
+    (synopsis "Get opening hours from OpenStreetMap")
+    (description
+     "This package provides a library for parsing and evaluating OpenStreetMap
+opening hours expressions.")
+    (license license:lgpl2.0+)))
+
+(define-public kosmindoormap
+  (package
+    (name "kosmindoormap")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://kde/stable/release-service/"
+                                  version "/src/" name "-" version ".tar.xz"))
+              (sha256
+               (base32
+                "042axwxa1497snr8f0m6a61gl9ypdkvllnhnlw4h5ffah7yl5n3s"))))
+    (build-system cmake-build-system)
+    (native-inputs (list bison extra-cmake-modules flex))
+    (inputs (list ki18n
+                  kopeninghours
+                  kpublictransport
+                  qtbase-5
+                  qtdeclarative-5
+                  zlib))
+    (home-page "https://invent.kde.org/libraries/kosmindoormap")
+    (synopsis "Indoor map renderer")
+    (description
+     "This package provides facilities for rendering OpenStreetMap
+multi-floor indoor maps.")
+    (license license:lgpl2.0+)))
+
 (define-public kpmcore
   (package
     (name "kpmcore")
-    (version "22.04.3")
+    (version "22.08.1")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -647,7 +839,7 @@ cards.")
                     "/src/" name "-" version ".tar.xz"))
               (sha256
                (base32
-                "04qslli4vnbnl329zynbinlwaigxr9xpswra5n0v710p92as0qif"))))
+                "1y28dnmbnkkjar4kl033fkmcnazgczc3pgdac2q1ry2hjzkcbnpa"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules pkg-config))
@@ -674,6 +866,37 @@ cards.")
     (description "Library for managing partitions.")
     (license license:gpl3+)))
 
+(define-public kpublictransport
+  (package
+    (name "kpublictransport")
+    (version "22.08.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append
+                    "mirror://kde/stable/release-service/" version
+                    "/src/kpublictransport-" version ".tar.xz"))
+              (sha256
+               (base32
+                "0z7zyyiq4815m74s6p841k1c4pxbrss7hnkag8kr5qa3q4264kg9"))))
+    (build-system qt-build-system)
+    (arguments
+     (list #:phases '(modify-phases %standard-phases
+                       (replace 'check
+                         (lambda* (#:key tests? #:allow-other-keys)
+                           (when tests?
+                             (setenv "QT_QPA_PLATFORM" "offscreen")
+                             (invoke "ctest" "-E"
+                              "(mergeutiltest|departuretest|journeytest|networkconfigtest|locationhistorymodeltest|navitiaparsertest|otpparsertest|ivvassparsertest|cachetest)")))))))
+    (native-inputs (list extra-cmake-modules pkg-config))
+    ;; TODO: clipper and osmctools are not detected
+    (inputs (list clipper osmctools protobuf qtdeclarative-5 zlib))
+    (home-page "https://api.kde.org/kdepim/kpublictransport/html/index.html")
+    (synopsis "Library for accessing realtime public transport data")
+    (description
+     "This package provides a library for accessing realtime public
+transport data and for performing public transport journey queries.")
+    (license (list license:lgpl2.0+))))
+
 (define-public snorenotify
   (package
     (name "snorenotify")
@@ -703,7 +926,7 @@ different notification systems.")
 (define-public kdeconnect
   (package
     (name "kdeconnect")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
       (origin
         (method url-fetch)
@@ -712,7 +935,7 @@ different notification systems.")
                             version ".tar.xz"))
         (sha256
          (base32
-          "015gxglclds2vmjr4bv51yfv840bafzgrl71cnwgnwwy8rrh9x4x"))))
+          "1yzx49gcm7x2wdk53iznyjz09y2a6mrrhh68xilbcsafyiw3l3zr"))))
     (build-system qt-build-system)
     (arguments
      `(#:configure-flags '("-DBUILD_TESTING=ON"
@@ -741,6 +964,7 @@ different notification systems.")
            kpeoplevcard
            kwayland
            libfakekey
+           plasma-wayland-protocols
            pulseaudio-qt
            qca
            qqc2-desktop-style
@@ -847,41 +1071,17 @@ to perform data analysis.")
     (license (list license:gpl2+     ;labplot
                    license:gpl3+)))) ;liborigin
 
-(define-public kqtquickcharts
-  (package
-    (name "kqtquickcharts")
-    (version "22.04.3")
-    (source
-      (origin
-        (method url-fetch)
-        (uri (string-append "mirror://kde/stable/release-service/"
-                            version "/src/kqtquickcharts-" version ".tar.xz"))
-        (sha256
-         (base32
-          "0bm7rdysvlfnfnvy87ii3kxl238q83vw0ia58zsnwjmkxmlgf6mp"))))
-    (build-system cmake-build-system)
-    (native-inputs
-     (list extra-cmake-modules))
-    (inputs
-     (list qtbase-5 qtdeclarative-5))
-    (home-page "https://phabricator.kde.org/source/kqtquickcharts/")
-    (synopsis "Interactive charts for Qt Quick")
-    (description
-     "Kqtquickcharts is a QtQuick plugin to render beautiful and interactive
-charts.")
-    (license license:lgpl2.1+)))
-
 (define-public kdf
   (package
     (name "kdf")
-    (version "22.04.3")
+    (version "22.08.1")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://kde/stable/release-service/"
                                   version "/src/kdf-" version ".tar.xz"))
               (sha256
                (base32
-                "1m0dwk3inqzk9kjjzgsaam15lnpbhzjfmwrzv8sazfk44scnr2v1"))))
+                "0p7iqld2phc74pmhyb8bqqg9clnc7l2rh6hd0i6jcsp266cgg205"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools))
@@ -934,14 +1134,14 @@ timers for each task can be started, stopped, changed, or looped.")
 (define-public kcachegrind
   (package
     (name "kcachegrind")
-    (version "22.04.3")
+    (version "22.08.1")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://kde/stable/release-service/" version
                                   "/src/kcachegrind-" version ".tar.xz"))
               (sha256
                (base32
-                "12ckn90hqm2c5c58xqkzgcih64jk4kwkgz4q0f5ns1rxv3pidz5n"))))
+                "05wcnfqs0fdfhfpagn0pqky0l7014nblv8r9fv1khy4g5mdlm4hs"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules perl python qttools-5 kdoctools))
@@ -968,14 +1168,14 @@ Python, PHP, and Perl.")
 (define-public libkdegames
   (package
     (name "libkdegames")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
       (method url-fetch)
       (uri (string-append "mirror://kde/stable/release-service/" version
                           "/src/libkdegames-" version ".tar.xz"))
       (sha256
-       (base32 "0igq87anam9x2mclb0lkvwhrxk62y1f4xl14a4dhd97mqsc5pbzn"))))
+       (base32 "1aihbha073fw2bxmdk4l768716kvrlyjd72x2nfx0vvr0ngc5wx9"))))
     (build-system qt-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1014,7 +1214,7 @@ Python, PHP, and Perl.")
 (define-public marble-qt
   (package
     (name "marble-qt")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method git-fetch)
@@ -1024,7 +1224,7 @@ Python, PHP, and Perl.")
        (file-name (git-file-name name version))
        (sha256
         (base32
-		"1saacnrl0hkl32nq96l1bgn9yrsz455q96jdxzp7ax8iaa5nmdiz"))))
+		"0pn0mjh5cg7mgjj82bsj8zikzdyq2fmzckdcav2y0msxwi859crl"))))
     (build-system qt-build-system)
     (arguments
      ;; FIXME: libmarblewidget-qt5.so.28 not found.  Also enable the
@@ -1071,14 +1271,14 @@ creating routes by drag and drop and more.")
 (define-public okular
   (package
     (name "okular")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/" name "-" version ".tar.xz"))
        (sha256
-        (base32 "03jpwgrhjgyx14g1h3lxhnyib88ck0qkqcxh4fpc398xwdr3amkw"))))
+        (base32 "0f98kfsb6sirpym27j2wwz4qr4p5vl4pbnckxd3gmgyfpz8mszln"))))
     (build-system qt-build-system)
     ;; The tests fail because they can't find the proper mimetype plugins:
     ;; "org.kde.okular.core: No plugin for mimetype '"image/jpeg"'."
@@ -1136,7 +1336,7 @@ a variety of formats, including PDF, PostScript, DejaVu, and EPub.")
 (define-public poxml
   (package
     (name "poxml")
-    (version "22.04.3")
+    (version "22.08.1")
     (source (origin
               (method url-fetch)
               (uri
@@ -1144,7 +1344,7 @@ a variety of formats, including PDF, PostScript, DejaVu, and EPub.")
                               "/src/poxml-" version ".tar.xz"))
               (sha256
                (base32
-                "1nrp0i3a39pw4pzcanpmjyks3pl1lyfj3zq61ii8xx402xw1ip2w"))))
+                "13jp5g5la3kq9i3qybdvwfl4vgqz3hxf64qzmh7kl71ykas7s5vi"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules kdoctools))
@@ -1161,14 +1361,14 @@ PO template files.")
 (define-public kdegraphics-mobipocket
   (package
     (name "kdegraphics-mobipocket")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/" name "-" version ".tar.xz"))
        (sha256
-        (base32 "12yrwa22c4qxsf10fv76fzaaj5xlv5lmrwcqvf6qhgr6f9qsw7sj"))))
+        (base32 "1kxvzgmq83hml10pc4j66r59dsar7h92w2i0cs1nhar781mz666n"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
@@ -1183,14 +1383,14 @@ Mobipocket e-books in Dolphin and other KDE apps.")
 (define-public libkexiv2
   (package
     (name "libkexiv2")
-    (version "22.04.3")
+    (version "22.08.1")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://kde/stable/release-service/" version
                            "/src/" name "-" version ".tar.xz"))
        (sha256
-        (base32 "0p43z69yh5jk8m1hn3xynjpgzxpkc89h0dafj5964qx4xp4vxl19"))))
+        (base32 "0iwpy79ppv4bbsqrszp9kmghgjvkl13gdpnafsbikh4wy1ch4cv9"))))
     (build-system cmake-build-system)
     (native-inputs
      (list extra-cmake-modules))
diff --git a/gnu/packages/linux.scm b/gnu/packages/linux.scm
index efb0f899aa..17db861422 100644
--- a/gnu/packages/linux.scm
+++ b/gnu/packages/linux.scm
@@ -33,7 +33,7 @@
 ;;; Copyright © 2018, 2019 Pierre Langlois <pierre.langlois@gmx.com>
 ;;; Copyright © 2018 Vasile Dumitrascu <va511e@yahoo.com>
 ;;; Copyright © 2019 Tim Gesthuizen <tim.gesthuizen@yahoo.de>
-;;; Copyright © 2019, 2020, 2021 Maxim Cournoyer <maxim.cournoyer@gmail.com>
+;;; Copyright © 2019, 2020, 2021, 2022 Maxim Cournoyer <maxim.cournoyer@gmail.com>
 ;;; Copyright © 2019 Stefan Stefanović <stefanx2ovic@gmail.com>
 ;;; Copyright © 2019-2022 Brice Waegeneire <brice@waegenei.re>
 ;;; Copyright © 2019 Kei Kebreau <kkebreau@posteo.net>
@@ -108,8 +108,9 @@
   #:use-module (gnu packages docbook)
   #:use-module (gnu packages documentation)
   #:use-module (gnu packages elf)
-  #:use-module (gnu packages flex)
   #:use-module (gnu packages file)
+  #:use-module (gnu packages flex)
+  #:use-module (gnu packages fontutils)
   #:use-module (gnu packages freedesktop)
   #:use-module (gnu packages gawk)
   #:use-module (gnu packages gcc)
@@ -119,6 +120,7 @@
   #:use-module (gnu packages gnupg)
   #:use-module (gnu packages golang)
   #:use-module (gnu packages gperf)
+  #:use-module (gnu packages graphviz)
   #:use-module (gnu packages gstreamer)
   #:use-module (gnu packages gtk)
   #:use-module (gnu packages haskell-apps)
@@ -418,7 +420,7 @@ corresponding UPSTREAM-SOURCE (an origin), using the given DEBLOB-SCRIPTS."
                             (%upstream-linux-source version hash)
                             deblob-scripts-5.4)))
 
-(define-public linux-libre-4.19-version "4.19.265")
+(define-public linux-libre-4.19-version "4.19.266")
 (define-public linux-libre-4.19-gnu-revision "gnu1")
 (define deblob-scripts-4.19
   (linux-libre-deblob-scripts
@@ -428,7 +430,7 @@ corresponding UPSTREAM-SOURCE (an origin), using the given DEBLOB-SCRIPTS."
    (base32 "00i91lx938nqlgy63hiricqd0fnbbf26vgya9c5lb7m1f4x324im")))
 (define-public linux-libre-4.19-pristine-source
   (let ((version linux-libre-4.19-version)
-        (hash (base32 "1l5cdpgng1gci1p1gdr2jzqw486h3w56gpyc7fbq74hlc6nnwh1p")))
+        (hash (base32 "0qfgvdzf8mwx0vhz6v6vkdch3hilh6qrl24gmy5z1vpwbxjvc4kv")))
     (make-linux-libre-source version
                              (%upstream-linux-source version hash)
                              deblob-scripts-4.19)))
@@ -494,17 +496,20 @@ corresponding UPSTREAM-SOURCE (an origin), using the given DEBLOB-SCRIPTS."
 (define-public linux-libre-6.0-source
   (source-with-patches linux-libre-6.0-pristine-source
                        (list %boot-logo-patch
-                             %linux-libre-arm-export-__sync_icache_dcache-patch)))
+                             %linux-libre-arm-export-__sync_icache_dcache-patch
+                             (search-patch "linux-libre-infodocs-target.patch"))))
 
 (define-public linux-libre-5.15-source
   (source-with-patches linux-libre-5.15-pristine-source
                        (list %boot-logo-patch
-                             %linux-libre-arm-export-__sync_icache_dcache-patch)))
+                             %linux-libre-arm-export-__sync_icache_dcache-patch
+                             (search-patch "linux-libre-infodocs-target.patch"))))
 
 (define-public linux-libre-5.10-source
   (source-with-patches linux-libre-5.10-pristine-source
                        (list %boot-logo-patch
-                             %linux-libre-arm-export-__sync_icache_dcache-patch)))
+                             %linux-libre-arm-export-__sync_icache_dcache-patch
+                             (search-patch "linux-libre-infodocs-target.patch"))))
 
 (define-public linux-libre-5.4-source
   (source-with-patches linux-libre-5.4-pristine-source
@@ -759,6 +764,11 @@ for ARCH and optionally VARIANT, or #f if there is no such configuration."
 ;;; Kernel package utilities.
 ;;;
 
+(define (doc-supported? version)
+  ;; Versions older than 5.10 have different enough build scripts that the
+  ;; infodocs patch doesn't apply.
+  (version>=? version "5.10"))
+
 (define* (make-linux-libre version gnu-revision hash-string supported-systems
                            #:key
                            (extra-version #f)
@@ -767,7 +777,13 @@ for ARCH and optionally VARIANT, or #f if there is no such configuration."
                            (configuration-file #f)
                            (defconfig "defconfig")
                            (extra-options %default-extra-linux-options)
-                           (patches (list %boot-logo-patch)))
+                           (build-doc? (doc-supported? version))
+                           (patches
+                            `(,%boot-logo-patch
+                              ,@(if build-doc?
+                                    (list (search-patch
+                                           "linux-libre-infodocs-target.patch"))
+                                    '()))))
   (make-linux-libre* version gnu-revision
                      (origin
                        (method url-fetch)
@@ -778,7 +794,8 @@ for ARCH and optionally VARIANT, or #f if there is no such configuration."
                      #:extra-version extra-version
                      #:configuration-file configuration-file
                      #:defconfig defconfig
-                     #:extra-options extra-options))
+                     #:extra-options extra-options
+                     #:build-doc? build-doc?))
 
 (define* (make-linux-libre* version gnu-revision source supported-systems
                             #:key
@@ -787,7 +804,10 @@ for ARCH and optionally VARIANT, or #f if there is no such configuration."
                             ;; See kernel-config for an example.
                             (configuration-file #f)
                             (defconfig "defconfig")
-                            (extra-options %default-extra-linux-options))
+                            (extra-options %default-extra-linux-options)
+                            (build-doc? (doc-supported? version)))
+  (when (and build-doc? (not (doc-supported? version)))
+    (error "unsupported 'build-doc?' for kernels <5.10"))
   (package
     (name (if extra-version
               (string-append "linux-libre-" extra-version)
@@ -796,11 +816,127 @@ for ARCH and optionally VARIANT, or #f if there is no such configuration."
     (source source)
     (supported-systems supported-systems)
     (build-system gnu-build-system)
+    (arguments
+     (list
+      #:modules '((guix build gnu-build-system)
+                  (guix build utils)
+                  (srfi srfi-1)
+                  (srfi srfi-26)
+                  (ice-9 ftw)
+                  (ice-9 match))
+      #:tests? #f
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'patch-/bin/pwd
+            (lambda _
+              (substitute* (find-files
+                            "." "^Makefile(\\.include)?$")
+                (("/bin/pwd") "pwd"))))
+          #$@(if build-doc?
+                 #~((add-before 'configure 'build-doc
+                      (lambda _
+                        (substitute* "Documentation/Makefile"
+                          ;; Remove problematic environment check script.
+                          ((".*scripts/sphinx-pre-install.*") ""))
+                        (invoke "make" "infodocs")))
+                    (add-after 'build-doc 'install-doc
+                      (lambda _
+                        (with-directory-excursion "Documentation/output"
+                          (invoke "make" "-C" "texinfo" "install-info"
+                                  (string-append "infodir=" #$output
+                                                 "/share/info"))))))
+                 #~())
+          (replace 'configure
+            (lambda* (#:key inputs target #:allow-other-keys)
+              ;; Avoid introducing timestamps.
+              (setenv "KCONFIG_NOTIMESTAMP" "1")
+              (setenv "KBUILD_BUILD_TIMESTAMP" (getenv "SOURCE_DATE_EPOCH"))
+
+              ;; Other variables useful for reproducibility.
+              (setenv "KBUILD_BUILD_USER" "guix")
+              (setenv "KBUILD_BUILD_HOST" "guix")
+
+              ;; Set ARCH and CROSS_COMPILE.
+              (let ((arch #$(platform-linux-architecture
+                             (lookup-platform-by-target-or-system
+                              (or (%current-target-system)
+                                  (%current-system))))))
+                (setenv "ARCH" arch)
+                (format #t "`ARCH' set to `~a'~%" (getenv "ARCH"))
+
+                (when target
+                  (setenv "CROSS_COMPILE" (string-append target "-"))
+                  (format #t "`CROSS_COMPILE' set to `~a'~%"
+                          (getenv "CROSS_COMPILE"))))
+
+              (setenv "EXTRAVERSION"
+                      #$(and extra-version
+                             (string-append "-" extra-version)))
+
+              (let ((config (assoc-ref inputs "kconfig")))
+
+                ;; Use a custom kernel configuration file or a default
+                ;; configuration file.
+                (if config
+                    (begin
+                      (copy-file config ".config")
+                      (chmod ".config" #o666))
+                    (invoke "make" #$defconfig))
+
+                ;; Appending works even when the option wasn't in the
+                ;; file.  The last one prevails if duplicated.
+                (let ((port (open-file ".config" "a"))
+                      (extra-configuration #$(config->string extra-options)))
+                  (display extra-configuration port)
+                  (close-port port))
+
+                (invoke "make" "oldconfig"))))
+          (replace 'install
+            (lambda* (#:key inputs native-inputs #:allow-other-keys)
+              (let ((moddir (string-append #$output "/lib/modules"))
+                    (dtbdir (string-append #$output "/lib/dtbs")))
+                ;; Install kernel image, kernel configuration and link map.
+                (for-each (lambda (file) (install-file file #$output))
+                          (find-files "." "^(\\.config|bzImage|zImage|Image\
+|vmlinuz|System\\.map|Module\\.symvers)$"))
+                ;; Install device tree files
+                (unless (null? (find-files "." "\\.dtb$"))
+                  (mkdir-p dtbdir)
+                  (invoke "make" (string-append "INSTALL_DTBS_PATH=" dtbdir)
+                          "dtbs_install"))
+                ;; Install kernel modules
+                (mkdir-p moddir)
+                (invoke "make"
+                        ;; Disable depmod because the Guix system's
+                        ;; module directory is an union of potentially
+                        ;; multiple packages.  It is not possible to use
+                        ;; depmod to usefully calculate a dependency
+                        ;; graph while building only one of them.
+                        "DEPMOD=true"
+                        (string-append "MODULE_DIR=" moddir)
+                        (string-append "INSTALL_PATH=" #$output)
+                        (string-append "INSTALL_MOD_PATH=" #$output)
+                        "INSTALL_MOD_STRIP=1"
+                        "modules_install")
+                (let* ((versions (filter (lambda (name)
+                                           (not (string-prefix? "." name)))
+                                         (scandir moddir)))
+                       (version (match versions
+                                  ((x) x))))
+                  ;; There are symlinks to the build and source directory.
+                  ;; Both will point to target /tmp/guix-build* and thus
+                  ;; not be useful in a profile.  Delete the symlinks.
+                  (false-if-file-not-found
+                   (delete-file
+                    (string-append moddir "/" version "/build")))
+                  (false-if-file-not-found
+                   (delete-file
+                    (string-append moddir "/" version "/source"))))))))))
     (native-inputs
      `(("perl" ,perl)
        ("bc" ,bc)
        ("openssl" ,openssl)
-       ("elfutils" ,elfutils)  ; Needed to enable CONFIG_STACK_VALIDATION
+       ("elfutils" ,elfutils)        ;needed to enable CONFIG_STACK_VALIDATION
        ("flex" ,flex)
        ("bison" ,bison)
 
@@ -809,6 +945,18 @@ for ARCH and optionally VARIANT, or #f if there is no such configuration."
        ("mpfr" ,mpfr)
        ("mpc" ,mpc)
 
+       ;; For generating the documentation.
+       ,@(if build-doc?
+             ;; TODO: remove fontconfig after the 5.10 kernel is dropped.
+             ;; Also replace python-wrapper by python at that time.
+             `(("fontconfig" ,fontconfig)
+               ("graphviz" ,graphviz)
+               ("python" ,python-wrapper)
+               ("python-sphinx" ,python-sphinx)
+               ("texinfo" ,texinfo)
+               ("which" ,which))
+             '())
+
        ,@(match (let ((arch (platform-linux-architecture
                              (lookup-platform-by-target-or-system
                               (or (%current-target-system)
@@ -817,115 +965,14 @@ for ARCH and optionally VARIANT, or #f if there is no such configuration."
                        (configuration-file
                         arch
                         #:variant (version-major+minor version))))
-           (#f                                    ;no config for this platform
+           (#f                          ;no config for this platform
             '())
            ((? string? config)
             `(("kconfig" ,config))))))
-    (arguments
-     (list #:modules '((guix build gnu-build-system)
-                       (guix build utils)
-                       (srfi srfi-1)
-                       (srfi srfi-26)
-                       (ice-9 ftw)
-                       (ice-9 match))
-           #:phases
-           #~(modify-phases %standard-phases
-               (add-after 'unpack 'patch-/bin/pwd
-                 (lambda _
-                   (substitute* (find-files "." "^Makefile(\\.include)?$")
-                     (("/bin/pwd") "pwd"))))
-               (replace 'configure
-                 (lambda* (#:key inputs target #:allow-other-keys)
-                   ;; Avoid introducing timestamps.
-                   (setenv "KCONFIG_NOTIMESTAMP" "1")
-                   (setenv "KBUILD_BUILD_TIMESTAMP"
-                           (getenv "SOURCE_DATE_EPOCH"))
-
-                   ;; Other variables useful for reproducibility.
-                   (setenv "KBUILD_BUILD_USER" "guix")
-                   (setenv "KBUILD_BUILD_HOST" "guix")
-
-                   ;; Set ARCH and CROSS_COMPILE.
-                   (let ((arch #$(platform-linux-architecture
-                                  (lookup-platform-by-target-or-system
-                                   (or (%current-target-system)
-                                       (%current-system))))))
-                     (setenv "ARCH" arch)
-                     (format #t "`ARCH' set to `~a'~%" (getenv "ARCH"))
-
-                     (when target
-                       (setenv "CROSS_COMPILE" (string-append target "-"))
-                       (format #t "`CROSS_COMPILE' set to `~a'~%"
-                               (getenv "CROSS_COMPILE"))))
-
-                   (setenv "EXTRAVERSION"
-                           #$(and extra-version
-                                  (string-append "-" extra-version)))
-
-                   (let ((config (assoc-ref inputs "kconfig")))
-
-                     ;; Use a custom kernel configuration file or a default
-                     ;; configuration file.
-                     (if config
-                         (begin
-                           (copy-file config ".config")
-                           (chmod ".config" #o666))
-                         (invoke "make" #$defconfig))
-
-                     ;; Appending works even when the option wasn't in the
-                     ;; file.  The last one prevails if duplicated.
-                     (let ((port (open-file ".config" "a"))
-                           (extra-configuration #$(config->string extra-options)))
-                       (display extra-configuration port)
-                       (close-port port))
-
-                     (invoke "make" "oldconfig"))))
-               (replace 'install
-                 (lambda* (#:key inputs native-inputs #:allow-other-keys)
-                   (let ((moddir (string-append #$output "/lib/modules"))
-                         (dtbdir (string-append #$output "/lib/dtbs")))
-                     ;; Install kernel image, kernel configuration and link map.
-                     (for-each (lambda (file) (install-file file #$output))
-                               (find-files "." "^(\\.config|bzImage|zImage|Image|vmlinuz|System\\.map|Module\\.symvers)$"))
-                     ;; Install device tree files
-                     (unless (null? (find-files "." "\\.dtb$"))
-                       (mkdir-p dtbdir)
-                       (invoke "make" (string-append "INSTALL_DTBS_PATH=" dtbdir)
-                               "dtbs_install"))
-                     ;; Install kernel modules
-                     (mkdir-p moddir)
-                     (invoke "make"
-                             ;; Disable depmod because the Guix system's
-                             ;; module directory is an union of potentially
-                             ;; multiple packages.  It is not possible to use
-                             ;; depmod to usefully calculate a dependency
-                             ;; graph while building only one of them.
-                             "DEPMOD=true"
-                             (string-append "MODULE_DIR=" moddir)
-                             (string-append "INSTALL_PATH=" #$output)
-                             (string-append "INSTALL_MOD_PATH=" #$output)
-                             "INSTALL_MOD_STRIP=1"
-                             "modules_install")
-                     (let* ((versions (filter (lambda (name)
-                                                (not (string-prefix? "." name)))
-                                              (scandir moddir)))
-                            (version (match versions
-                                       ((x) x))))
-                       ;; There are symlinks to the build and source directory.
-                       ;; Both will point to target /tmp/guix-build* and thus
-                       ;; not be useful in a profile.  Delete the symlinks.
-                       (false-if-file-not-found
-                        (delete-file
-                         (string-append moddir "/" version "/build")))
-                       (false-if-file-not-found
-                        (delete-file
-                         (string-append moddir "/" version "/source"))))))))
-           #:tests? #f))
     (home-page "https://www.gnu.org/software/linux-libre/")
     (synopsis "100% free redistribution of a cleaned Linux kernel")
-    (description
-     "GNU Linux-Libre is a free (as in freedom) variant of the Linux kernel.
-It has been modified to remove all non-free binary blobs.")
+    (description "GNU Linux-Libre is a free (as in freedom) variant of the
+Linux kernel.  It has been modified to remove all non-free binary blobs.")
     (license license:gpl2)
     (properties '((max-silent-time . 3600))))) ;don't timeout on blob scan.
 
@@ -5555,7 +5602,7 @@ and copy/paste text in the console and in xterm.")
 (define-public btrfs-progs
   (package
     (name "btrfs-progs")
-    (version "5.18.1")
+    (version "6.0.1")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://kernel.org/linux/kernel/"
@@ -5563,7 +5610,7 @@ and copy/paste text in the console and in xterm.")
                                   "btrfs-progs-v" version ".tar.xz"))
               (sha256
                (base32
-                "0mbj3j2fpjds9i9gm8kk8a20yjacc562ibd1v9a96bpmrxfag63f"))))
+                "0j0w400fg0lbzljmcwq553cv0awixc4k35v7l39jl7l13pznycdm"))))
     (build-system gnu-build-system)
     (outputs '("out"
                "static"))      ; static versions of the binaries in "out"
@@ -8456,7 +8503,7 @@ compatible with Python's ConfigParser style of .INI files, including RFC
 (define-public xfsprogs
   (package
     (name "xfsprogs")
-    (version "5.14.2")
+    (version "6.0.0")
     (source (origin
               (method url-fetch)
               (uri (string-append
@@ -8464,7 +8511,7 @@ compatible with Python's ConfigParser style of .INI files, including RFC
                     "xfsprogs-" version ".tar.gz"))
               (sha256
                (base32
-                "0368dacdjq55ip38yizs9spdyl7b0b1c0vz3gr1gvcb9rw3a6dnp"))))
+                "14hc61nfc73nqwhyasc4haj5g7046im1dwz61bx338f86mjj5n5y"))))
     (build-system gnu-build-system)
     (outputs (list "out" "python"))
     (arguments
@@ -8503,6 +8550,20 @@ file systems.")
     ;; licensed under lgpl2.1. the other stuff is licensed under gpl2.
     (license (list license:gpl2 license:lgpl2.1))))
 
+(define-public xfsprogs-5.9
+  (package
+    (inherit xfsprogs)
+    (name "xfsprogs")
+    (version "5.9.0")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append
+                    "mirror://kernel.org/linux/utils/fs/xfs/xfsprogs/"
+                    "xfsprogs-" version ".tar.gz"))
+              (sha256
+               (base32
+                "13xkn9jpmwp4fm9r68vhgznkmxhnv83n2b39mhy2qdaph90w2a1l"))))))
+
 (define-public xfsprogs/static
   (package
     (inherit xfsprogs)
diff --git a/gnu/packages/lisp-check.scm b/gnu/packages/lisp-check.scm
index 7002cd9d92..038ca1f18b 100644
--- a/gnu/packages/lisp-check.scm
+++ b/gnu/packages/lisp-check.scm
@@ -94,6 +94,90 @@ consists of: @code{test}, @code{is}, @code{signals}, @code{finishes},
 (define-public ecl-2am
   (sbcl-package->ecl-package sbcl-2am))
 
+(define-public sbcl-assertion-error
+  (let ((commit "8eab692a990d4caa193a46bae99af3e13e717b86")
+        (revision "1"))
+    (package
+      (name "sbcl-assertion-error")
+      (version (git-version "0.1.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/noloop/assertion-error")
+               (commit commit)))
+         (file-name (git-file-name "assertion-error" version))
+         (sha256
+          (base32 "0ix23kkakmf4nwx852zsssb831jvajr3qyppqfyks7y1ls617svn"))))
+      (build-system asdf-build-system/sbcl)
+      (inputs (list sbcl-dissect))
+      (home-page "https://github.com/noloop/assertion-error")
+      (synopsis "Error pattern for assertion libraries in Common Lisp")
+      (description "This package provides a Common Lisp assertion system with
+minimal dependencies on DISSECT.")
+      (license license:gpl3))))
+
+(define-public ecl-assertion-error
+  (sbcl-package->ecl-package sbcl-assertion-error))
+
+(define-public cl-assertion-error
+  (sbcl-package->cl-source-package sbcl-assertion-error))
+
+(define-public sbcl-assert-p
+  (package
+    (name "sbcl-assert-p")
+    (version "1.0.1")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/noloop/assert-p")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name "assert-p" version))
+       (sha256
+        (base32 "1x24rkqkqiw8zd26swi9rmhfplkmr5scz3bhjwccah9d2s36b1xs"))))
+    (build-system asdf-build-system/sbcl)
+    (inputs (list sbcl-assertion-error sbcl-simplet))
+    (home-page "https://github.com/noloop/assert-p")
+    (synopsis "Common Lisp assertion library")
+    (description "This package provides a Common Lisp collection of assertions.")
+    (license license:gpl3)))
+
+(define-public ecl-assert-p
+  (sbcl-package->ecl-package sbcl-assert-p))
+
+(define-public cl-assert-p
+  (sbcl-package->cl-source-package sbcl-assert-p))
+
+(define-public sbcl-cacau
+  (package
+    (name "sbcl-cacau")
+    (version "1.0.0")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/noloop/cacau")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name "cacau" version))
+       (sha256
+        (base32 "0m8v1xw68cr5ldv045rxgvnhigr4iahh7v6v32z6xlq2sj6r55x0"))))
+    (build-system asdf-build-system/sbcl)
+    (native-inputs (list sbcl-assert-p))
+    (inputs (list sbcl-assertion-error sbcl-eventbus))
+    (home-page "https://github.com/noloop/cacau")
+    (synopsis "Comon Lisp test runner")
+    (description
+     "This package provides a Common Lisp testing framework system CACAU which was
+built to be independent of assertions systems.")
+    (license license:gpl3)))
+
+(define-public ecl-cacau
+  (sbcl-package->ecl-package sbcl-cacau))
+
+(define-public cl-cacau
+  (sbcl-package->cl-source-package sbcl-cacau))
+
 (define-public sbcl-check-it
   (let ((commit "b79c9103665be3976915b56b570038f03486e62f"))
     (package
@@ -634,11 +718,11 @@ by Chris Riesbeck.")
   (sbcl-package->cl-source-package sbcl-nst))
 
 (define-public sbcl-parachute
-  (let ((commit "86563473dc23fb1277d35a3ad2c911a6c8e5b0da")
-        (revision "1"))
+  (let ((commit "8bc3e1b5a1808341967aeb89516f9fab23cd1d9e")
+        (revision "0"))
     (package
       (name "sbcl-parachute")
-      (version (git-version "1.1.1" revision commit))
+      (version (git-version "1.5.0" revision commit))
       (source
        (origin
          (method git-fetch)
@@ -646,13 +730,14 @@ by Chris Riesbeck.")
           (git-reference
            (url "https://github.com/Shinmera/parachute")
            (commit commit)))
-         (file-name (git-file-name name version))
+         (file-name (git-file-name "cl-parachute" version))
          (sha256
-          (base32
-           "026crl465xqh3fnskfd4c1sxa9c33dfy702cf3l5apbjyj1dg20n"))))
+          (base32 "0cppp1sp9xqkgxgkwidhqzlsj03ywnar7z9mzwcliww8y0kv5555"))))
       (build-system asdf-build-system/sbcl)
       (inputs
-       (list sbcl-documentation-utils sbcl-form-fiddle))
+       (list sbcl-documentation-utils
+             sbcl-form-fiddle
+             sbcl-trivial-custom-debugger))
       (synopsis "Extensible and cross-compatible testing framework for Common Lisp")
       (description
        "Parachute is a simple-to-use and extensible testing framework.
@@ -840,6 +925,32 @@ take.")
 (define-public ecl-should-test
   (sbcl-package->ecl-package sbcl-should-test))
 
+(define-public sbcl-simplet
+  (package
+    (name "sbcl-simplet")
+    (version  "1.2.0")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/noloop/simplet")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name "simplet" version))
+       (sha256
+        (base32 "1iwp3a43mns885k2arr7gbmyv5rsrjfvgarxickj7r2bfgwp1cnn"))))
+    (build-system asdf-build-system/sbcl)
+    (home-page "https://github.com/noloop/simplet")
+    (synopsis "Simple test runner in Common Lisp")
+    (description "This package provides a Common Lisp test runner system
+SIMPLET.")
+    (license license:gpl3)))
+
+(define-public ecl-simplet
+  (sbcl-package->ecl-package sbcl-simplet))
+
+(define-public cl-simplet
+  (sbcl-package->cl-source-package sbcl-simplet))
+
 (define-public sbcl-stefil
   (let ((commit "0398548ec95dceb50fc2c2c03e5fb0ce49b86c7a")
         (revision "0"))
diff --git a/gnu/packages/lisp-xyz.scm b/gnu/packages/lisp-xyz.scm
index 27312cb369..ad2da5fa82 100644
--- a/gnu/packages/lisp-xyz.scm
+++ b/gnu/packages/lisp-xyz.scm
@@ -490,6 +490,39 @@ interface to the Linux inotify API.")
 (define-public ecl-cl-inotify
   (sbcl-package->ecl-package sbcl-cl-inotify))
 
+(define-public sbcl-file-notify
+  (let ((commit "f12dc2f2aae5fee13355cd93a8cae0c4c412b76d")
+        (revision "0"))
+    (package
+      (name "sbcl-file-notify")
+      (version (git-version "1.0.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/Shinmera/file-notify")
+               (commit commit)))
+         (file-name (git-file-name "cl-file-notify" version))
+         (sha256
+          (base32 "0788d98rqm1krl8nbfh8qshvyf6g336i9bqrdhkx06cfvbh0wcny"))))
+      (build-system asdf-build-system/sbcl)
+      (inputs
+       (list sbcl-cffi
+             sbcl-documentation-utils
+             sbcl-trivial-features))
+      (home-page "https://github.com/Shinmera/file-notify")
+      (synopsis "Get notifications for file accesses and changes")
+      (description
+       "File-Notify is a Common Lisp library for getting notifications for file
+accesses and changes.")
+      (license license:zlib))))
+
+(define-public cl-file-notify
+  (sbcl-package->cl-source-package sbcl-file-notify))
+
+(define-public ecl-file-notify
+  (sbcl-package->ecl-package sbcl-file-notify))
+
 (define-public sbcl-bodge-queue
   (let ((commit "948c9a501dcd412689952d09eb7453ec2722336a")
         (revision "0"))
@@ -708,6 +741,36 @@ or cl-launch for portable processing of command-line arguments.")
 (define-public cl-command-line-arguments
   (sbcl-package->cl-source-package sbcl-command-line-arguments))
 
+(define-public sbcl-adopt
+  (package
+    (name "sbcl-adopt")
+    (version "1.2.0")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/sjl/adopt")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name "cl-adopt" version))
+       (sha256
+        (base32 "16kzkai96qk7vmclp8wxc9aghhnisw8gg9s7hra68300bgj86wzr"))))
+    (build-system asdf-build-system/sbcl)
+    (native-inputs (list sbcl-1am))
+    (inputs (list sbcl-bobbin sbcl-split-sequence))
+    (home-page "https://hg.stevelosh.com/adopt")
+    (synopsis "Common Lisp option parsing library")
+    (description
+     "@acronym{ADOPT, A Damn OPTion} is a simple UNIX-style option parser in
+Common Lisp, heavily influenced by Python's @code{optparse} and
+@code{argparse}.")
+    (license license:expat)))
+
+(define-public ecl-adopt
+  (sbcl-package->ecl-package sbcl-adopt))
+
+(define-public cl-adopt
+  (sbcl-package->cl-source-package sbcl-adopt))
+
 (define-public sbcl-cl-irc
   (let ((commit "963823537c7bfcda2edd4c44d172192da6722175")
         (revision "0"))
@@ -1049,6 +1112,59 @@ compatible with ANSI-compliant Common Lisp implementations.")
 (define-public ecl-cl-ppcre
   (sbcl-package->ecl-package sbcl-cl-ppcre))
 
+(define-public sbcl-one-more-re-nightmare
+  (let ((commit "09c33feed35797512bf123ccca053cf8ba42bfbd")
+        (revision "0"))
+    (package
+      (name "sbcl-one-more-re-nightmare")
+      (version (git-version "0.0.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/telekons/one-more-re-nightmare")
+               (commit commit)))
+         (file-name (git-file-name "cl-one-more-re-nightmare" version))
+         (sha256
+          (base32 "0vc0lxvn3anjb63hr26r1l18aw5nbj80w9ja3a32fip6nbwfsrfv"))))
+      (build-system asdf-build-system/sbcl)
+      (arguments
+       '(#:asd-test-systems '("one-more-re-nightmare-tests")
+         #:phases
+         (modify-phases %standard-phases
+           (add-after 'unpack 'fix-tests
+             (lambda _
+               (substitute* "Tests/one-more-re-nightmare-tests.asd"
+                 ((":depends-on")
+                  (string-append
+                   ":perform (test-op (o c) (symbol-call :one-more-re-nightmare-tests '#:run-tests))"
+                   "\n  :depends-on"))))))))
+      (native-inputs
+       (list sbcl-lparallel sbcl-parachute))
+      (inputs
+       (list sbcl-alexandria
+             sbcl-babel
+             sbcl-bordeaux-threads
+             sbcl-dynamic-mixins
+             sbcl-esrap
+             sbcl-stealth-mixin
+             sbcl-trivia
+             sbcl-trivial-indent))
+      (home-page "https://github.com/telekons/one-more-re-nightmare")
+      (synopsis "Regular expression compiler in Common Lisp")
+      (description "@code{one-more-re-nightmare} is a regular expression engine
+that uses the technique presented in Regular-expression derivatives
+re-examined (Owens, Reppy and Turon, 2009;
+@url{doi:10.1017/S0956796808007090}) to interpret and compile regular
+expressions.")
+      (license license:bsd-2))))
+
+(define-public cl-one-more-re-nightmare
+  (sbcl-package->cl-source-package sbcl-one-more-re-nightmare))
+
+(define-public ecl-one-more-re-nightmare
+  (sbcl-package->ecl-package sbcl-one-more-re-nightmare))
+
 (define-public sbcl-parse
   (let ((commit "2351ee78acac065fcf10b8713d3f404e2e910786")
         (revision "1"))
@@ -2971,6 +3087,89 @@ pretty, documentation is code.")
 (define-public ecl-mgl-pax
   (sbcl-package->ecl-package sbcl-mgl-pax))
 
+(define-public sbcl-40ants-doc
+  (let ((commit "7725ff67a380e9ebfc6155e14d91e650f256711b")
+        (revision "0"))
+    (package
+      (name "sbcl-40ants-doc")
+      (version (git-version "0.1.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/40ants/doc")
+               (commit commit)))
+         (sha256
+          (base32 "1v6gnhrk02vsixmprzk4wvvj7vh11vp5waxyih0qz2ih8d38r5pg"))
+         (file-name (git-file-name "cl-40ants-doc" version))))
+      (build-system asdf-build-system/sbcl)
+      (arguments
+       ;; TODO: Add remaining dependencies of 40ants-doc-full and
+       ;; 40ants-doc-test missing from Guix.
+       '(#:asd-systems '("40ants-doc"
+                         ;;"40ants-doc-full"
+                         )
+         #:tests? #f))
+      ;;(native-inputs
+      ;; (list sbcl-rove))
+      (inputs
+       (list sbcl-named-readtables
+             sbcl-pythonic-string-reader
+             ;; For 40ants-doc-full:
+             ;;sbcl-3bmd
+             ;;sbcl-alexandria
+             ;;sbcl-babel
+             ;;sbcl-cl-cookie
+             ;;sbcl-cl-fad
+             ;;sbcl-cl-ppcre
+             ;;sbcl-common-doc         ; Missing from Guix
+             ;;sbcl-common-html        ; Missing from Guix
+             ;;sbcl-commondoc-markdown ; Missing from Guix
+             ;;sbcl-dexador
+             ;;sbcl-docs-builder       ; Missing from Guix
+             ;;sbcl-fare-utils
+             ;;sbcl-jonathan
+             ;;sbcl-lass
+             ;;sbcl-local-time
+             ;;sbcl-log4cl
+             ;;sbcl-slime-swank
+             ;;sbcl-slynk
+             ;;sbcl-spinneret
+             ;;sbcl-stem ; Missing from Guix; also, license is unconfirmed
+             ;;sbcl-str
+             ;;sbcl-tmpdir          ; Missing from Guix
+             ;;sbcl-trivial-extract ; Missing from Guix
+             ;;sbcl-xml-emitter
+             ))
+      (home-page "https://40ants.com/doc/")
+      (synopsis "Exploratory programming environment and documentation generator")
+      (description
+       "@code{40ants-doc} provides a rudimentary explorable programming
+environment.  The narrative primarily lives in so-called sections that mix
+Markdown docstrings with references to functions, variables, etc., all of
+which should probably have their own docstrings.
+
+The primary focus is on making code easily explorable by using SLIME's
+@kbd{M-.} (@code{slime-edit-definition}).  Generating documentation in
+Markdown or HTML format from sections and all the referenced items is also
+implemented.
+
+With the simplistic tools provided, one may obtain results similar to literate
+programming, but documentation is generated from code, not the other way
+around, and there is no support for chunking.  Code comes first, code must
+look pretty, documentation is code.
+
+@code{40ants-doc} is a fork of MGL-PAX with fewer dependencies (only
+@code{named-readtables} and @code{pythonic-string-reader}) for the core
+system, and additional features in the full system.")
+      (license license:expat))))
+
+(define-public cl-40ants-doc
+  (sbcl-package->cl-source-package sbcl-40ants-doc))
+
+(define-public ecl-40ants-doc
+  (sbcl-package->ecl-package sbcl-40ants-doc))
+
 (define-public sbcl-mssql
   (let ((commit "045602a19a32254108f2b75871049293f49731eb")
         (revision "1"))
@@ -7600,8 +7799,8 @@ extension-points via the concept of hooks.")
 
 (define-public sbcl-s-sysdeps
   ;; No release since 2013.
-  (let ((commit "9aa23bbdceb24bcdbe0e7c39fa1901858f823106")
-        (revision "2"))
+  (let ((commit "7f8de283b7fbd8b038fdf08493063a736db36ce7")
+        (revision "3"))
     (package
       (name "sbcl-s-sysdeps")
       (build-system asdf-build-system/sbcl)
@@ -7616,7 +7815,7 @@ extension-points via the concept of hooks.")
          (file-name (git-file-name name version))
          (sha256
           (base32
-           "1fh8r7kf8s3hvqdg6b71b8p7w3v2kkga9bw8j3qqdxhzr6anpm0b"))))
+           "0rp81iq0rgl48qdwbmfy89glga81hmry2lp8adjbr5h5ybr92b4n"))))
       (inputs
        (list sbcl-bordeaux-threads sbcl-usocket))
       (synopsis "Common Lisp abstraction layer over platform dependent functionality")
@@ -7641,8 +7840,8 @@ number of other projects.
   (sbcl-package->ecl-package sbcl-s-sysdeps))
 
 (define-public sbcl-cl-prevalence
-  (let ((commit "5a76be036092ed6c18cb695a9e03bce87e21b840")
-        (revision "4"))
+  (let ((commit "e6b27640ce89ae5f8af38beb740e319bb6cd2368")
+        (revision "6"))
     (package
       (name "sbcl-cl-prevalence")
       (build-system asdf-build-system/sbcl)
@@ -7657,11 +7856,11 @@ number of other projects.
          (file-name (git-file-name name version))
          (sha256
           (base32
-           "050h6hwv8f16b5v6fzba8zmih92hgaaq27i2x9wv1iib41gbia3r"))))
+           "1lb957ivshgp56phqhvhsmnc4r55x5shvi3mpsan2xsm4hvqspp0"))))
       (inputs
-       (list sbcl-s-sysdeps sbcl-s-xml))
+       (list sbcl-moptilities sbcl-s-sysdeps sbcl-s-xml))
       (native-inputs
-       (list sbcl-fiveam))
+       (list sbcl-fiveam sbcl-find-port))
       (synopsis "Implementation of object prevalence for Common Lisp")
       (description "This Common Lisp library implements object prevalence (see
 @url{https://en.wikipedia.org/wiki/System_prevalence}).  It allows
@@ -8820,8 +9019,8 @@ macro.  This library provides a set of simple utilities to help with that.")
   (sbcl-package->ecl-package sbcl-form-fiddle))
 
 (define-public sbcl-array-utils
-  (let ((commit "f90eb9070d0b2205af51126a35033574725e5c56")
-        (revision "0"))
+  (let ((commit "40cea8fc895add87d1dba9232da817750222b528")
+        (revision "1"))
     (package
       (name "sbcl-array-utils")
       (version (git-version "1.1.1" revision commit))
@@ -8832,10 +9031,9 @@ macro.  This library provides a set of simple utilities to help with that.")
           (git-reference
            (url "https://github.com/Shinmera/array-utils")
            (commit commit)))
-         (file-name (git-file-name name version))
+         (file-name (git-file-name "cl-array-utils" version))
          (sha256
-          (base32
-           "0zhwfbpr53vs1ii4sx75dz2k9yhh1xpwdqqpg8nmfndxkmhpbi3x"))))
+          (base32 "0d7nddak8h2aa82z11vdbd97srk5bdgq41pzmibsz3ymspnndicd"))))
       (build-system asdf-build-system/sbcl)
       (native-inputs
        (list sbcl-parachute))
@@ -8889,8 +9087,8 @@ LASS files.")
   (sbcl-package->ecl-package sbcl-lass))
 
 (define-public sbcl-plump
-  (let ((commit "3584275f0be9d06c0c51b5c08f89005deafc4ada")
-        (revision "2"))
+  (let ((commit "0c3e0b57b43b6e0c5794b6a902f1cf5bee2a2927")
+        (revision "3"))
     (package
       (name "sbcl-plump")
       (version (git-version "2.0.0" revision commit))
@@ -8901,10 +9099,9 @@ LASS files.")
           (git-reference
            (url "https://github.com/Shinmera/plump")
            (commit commit)))
-         (file-name (git-file-name name version))
+         (file-name (git-file-name "cl-plump" version))
          (sha256
-          (base32
-           "1w4wz7f6dc2ckdq9wq9r5014bg2nxjifj9yz1zzn41r8h1h5xfcd"))))
+          (base32 "1fyb66pqvr1iy31ah9638ihs8cax17zkxk0zq14jy7x5l9rq1qlf"))))
       (build-system asdf-build-system/sbcl)
       (inputs
        (list sbcl-array-utils sbcl-documentation-utils))
@@ -9362,6 +9559,103 @@ archives such as those generated by the tar and cpio programs on Unix.")
 (define-public ecl-archive
   (sbcl-package->ecl-package sbcl-archive))
 
+(define-public sbcl-tar-file
+  (let ((commit "0c10bc82f14702c97a26dc25ce075b5d3a2347d1")
+        (revision "0"))
+    (package
+      (name "sbcl-tar-file")
+      (version (git-version "0.2.1" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://gitlab.common-lisp.net/cl-tar/cl-tar-file")
+               (commit commit)))
+         (file-name (git-file-name "cl-tar-file" version))
+         (sha256
+          (base32 "0i8j05fkgdqy4c4pqj0c68sh4s3klpx9kc5wp73qwzrl3xqd2svy"))))
+      (build-system asdf-build-system/sbcl)
+      (native-inputs
+       (list sbcl-parachute))
+      (inputs
+       (list sbcl-40ants-doc
+             sbcl-alexandria
+             sbcl-babel
+             sbcl-chipz
+             sbcl-flexi-streams
+             sbcl-salza2
+             sbcl-trivial-gray-streams))
+      (home-page "https://gitlab.common-lisp.net/cl-tar/cl-tar-file")
+      (synopsis "Read and write physical entries to and from tar files")
+      (description
+       "@code{cl-tar-file} is a Common Lisp library that allows reading from
+and writing to various tar archive formats.  Currently supported are the POSIX
+ustar, PAX (ustar with a few new entry types), GNU, and v7 (very old) formats.
+
+This library is rather low level and is focused exclusively on reading and
+writing physical tar file entries using streams.  Therefore, it contains no
+functionality for automatically building archives from a set of files on the
+filesystem or writing the contents of a file to the filesystem.  Additionally,
+there are no smarts that read multiple physical entries and combine them into
+a single logical entry (e.g., with PAX extended headers or GNU long link/path
+name support).  For a higher-level library that reads and writes logical
+entries, and also includes filesystem integration, see @code{cl-tar}.")
+      (license license:bsd-3))))
+
+(define-public cl-tar-file
+  (sbcl-package->cl-source-package sbcl-tar-file))
+
+(define-public ecl-tar-file
+  (sbcl-package->ecl-package sbcl-tar-file))
+
+(define-public sbcl-tar
+  (let ((commit "7c6e07a10c93d9e311f087b5f6328cddd481669a")
+        (revision "0"))
+    (package
+      (name "sbcl-tar")
+      (version (git-version "0.2.3" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://gitlab.common-lisp.net/cl-tar/cl-tar")
+               (commit commit)))
+         (file-name (git-file-name "cl-tar" version))
+         (sha256
+          (base32 "0wp23cs3i6a89dibifiz6559la5nk58d1n17xvbxq4nrl8cqsllf"))))
+      (build-system asdf-build-system/sbcl)
+      ;; TODO: Build the tar program with 'build-program' when the
+      ;; 'asdf-release-ops' library is added to Guix.
+      (arguments
+       '(#:asd-systems '("tar"
+                         "tar/common-extract"
+                         "tar/create"
+                         "tar/docs"
+                         "tar/extract"
+                         "tar/simple-extract")))
+      (native-inputs
+       (list sbcl-parachute))
+      (inputs
+       (list sbcl-40ants-doc
+             sbcl-alexandria
+             sbcl-babel
+             sbcl-local-time
+             sbcl-osicat
+             sbcl-split-sequence
+             sbcl-tar-file))
+      (home-page "https://gitlab.common-lisp.net/cl-tar/cl-tar")
+      (synopsis "High-level interface for tar files")
+      (description
+       "@code{cl-tar} is a Common Lisp library providing a high-level interface
+for interacting with tar archives.")
+      (license license:expat))))
+
+(define-public cl-tar
+  (sbcl-package->cl-source-package sbcl-tar))
+
+(define-public ecl-tar
+  (sbcl-package->ecl-package sbcl-tar))
+
 (define-public sbcl-misc-extensions
   (let ((commit "101c05112bf2f1e1bbf527396822d2f50ca6327a")
         (revision "1"))
@@ -12800,6 +13094,44 @@ than a few Kb.")
 (define-public ecl-mmap
   (sbcl-package->ecl-package sbcl-mmap))
 
+(define-public sbcl-marray
+  (let ((commit "0352f316b6830f0b119088ba9be836e4726bd7d8")
+        (revision "0"))
+    (package
+      (name "sbcl-marray")
+      (version (git-version "0.0.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/death/marray")
+               (commit commit)))
+         (file-name (git-file-name "cl-marray" version))
+         (sha256
+          (base32 "0l4kvzpiw14vqhlsaflp3c7y51vznjjgbdi0q3axqk1wxvzy1zlx"))))
+      (build-system asdf-build-system/sbcl)
+      (arguments
+       '(#:phases
+         (modify-phases %standard-phases
+           (add-after 'unpack 'fix-dependencies
+             (lambda _
+               (substitute* "marray.asd"
+                 ((":components")
+                  ":depends-on (#+sbcl \"sb-posix\")\n  :components")))))))
+      (home-page "https://github.com/death/marray")
+      (synopsis "Memory-mapped files as Common Lisp arrays")
+      (description
+       "MARRAY is a library which provides access to memory-mapped files
+through Common Lisp arrays.")
+      (license license:expat))))
+
+(define-public cl-marray
+  (sbcl-package->cl-source-package sbcl-marray))
+
+;; ECL support not implemented yet.
+;; (define-public ecl-marray
+;;   (sbcl-package->ecl-package sbcl-marray))
+
 (define-public sbcl-3bz
   (let ((commit "569614c40408f3aefc77ba233e0e4bd66d3850ad")
         (revision "1"))
@@ -13971,6 +14303,39 @@ directly.")
 (define-public ecl-custom-hash-table
   (sbcl-package->ecl-package sbcl-custom-hash-table))
 
+(define-public sbcl-concurrent-hash-tables
+  (let ((commit "1b9f0b5da54fece4f42296e1bdacfcec0c370a5a")
+        (revision "0"))
+    (package
+      (name "sbcl-concurrent-hash-tables")
+      (version (git-version "0.0.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/no-defun-allowed/concurrent-hash-tables")
+               (commit commit)))
+         (file-name (git-file-name "cl-concurrent-hash-tables" version))
+         (sha256
+          (base32 "03g24ycr1ngzg8bv10iwp1bmnldz5bxbfdqrzhfxhicpibh49r96"))))
+      (build-system asdf-build-system/sbcl)
+      (inputs
+       (list sbcl-atomics sbcl-bordeaux-threads))
+      (home-page "https://github.com/no-defun-allowed/concurrent-hash-tables")
+      (synopsis "Portability library for concurrent hash tables in Common Lisp")
+      (description "@code{concurrent-hash-tables} is a Common Lisp portability
+library wrapping some implementations of concurrent hash tables which do not
+have to be entirely locked in their operation, including
+@code{42nd-at-threadmill}, @code{luckless}, and a fallback, segmented hash
+table.")
+      (license license:bsd-2))))
+
+(define-public cl-concurrent-hash-tables
+  (sbcl-package->cl-source-package sbcl-concurrent-hash-tables))
+
+(define-public ecl-concurrent-hash-tables
+  (sbcl-package->ecl-package sbcl-concurrent-hash-tables))
+
 (define-public sbcl-collectors
   (let ((commit "13acef25d8422d1d82e067b1861e513587c166ee"))
     (package
@@ -14272,6 +14637,34 @@ with a complex event filtering system.")
 (define-public ecl-deeds
   (sbcl-package->ecl-package sbcl-deeds))
 
+(define-public sbcl-eventbus
+  (let ((commit "92c1fa3846ba0e3cc9e6d7605d765379c8658d84")
+        (revision "1"))
+    (package
+      (name "sbcl-eventbus")
+      (version (git-version "0.1.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/noloop/eventbus")
+               (commit commit)))
+         (file-name (git-file-name "eventbus" version))
+         (sha256
+          (base32 "0slqx3zq6sbz3rg4g79j8y25sx4405y6ff3x6l5v8v4v42m1s0p2"))))
+      (build-system asdf-build-system/sbcl)
+      (native-inputs (list sbcl-simplet))
+      (home-page "https://github.com/noloop/eventbus")
+      (synopsis "Event bus implementation in Common Lisp")
+      (description "This package provides a Common Lisp system implementing event bus.")
+      (license license:gpl3))))
+
+(define-public ecl-eventbus
+  (sbcl-package->ecl-package sbcl-eventbus))
+
+(define-public cl-eventbus
+  (sbcl-package->cl-source-package sbcl-eventbus))
+
 (define-public sbcl-make-hash
   ;; no tagged branch
   (let ((revision "1")
@@ -15014,6 +15407,80 @@ even by adding additional statistical @code{compute}ations.")
 (define-public ecl-trivial-benchmark
   (sbcl-package->ecl-package sbcl-trivial-benchmark))
 
+(define-public sbcl-the-cost-of-nothing
+  (let ((commit "f364029fbbf37ae5786f2f9ddf6185dd204a7185")
+        (revision "0"))
+    (package
+      (name "sbcl-the-cost-of-nothing")
+      (version (git-version "0.0.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/marcoheisig/the-cost-of-nothing")
+               (commit commit)))
+         (file-name (git-file-name "cl-the-cost-of-nothing" version))
+         (sha256
+          (base32 "1ccrglyr1wnnfp218w1qj7yfl4yzlxkki3hqaifi5axgbi5dmmh8"))))
+      (build-system asdf-build-system/sbcl)
+      (arguments
+       ;; The test operation benchmarks the Common Lisp implementation; it
+       ;; doesn't test the package.
+       (list #:tests? #f))
+      (inputs
+       (list sbcl-alexandria
+             sbcl-closer-mop
+             sbcl-local-time
+             sbcl-trivial-garbage))
+      (home-page "https://github.com/marcoheisig/the-cost-of-nothing")
+      (synopsis "Measure the run time of Common Lisp code")
+      (description
+       "THE-COST-OF-NOTHING is a library for measuring the run time of Common
+Lisp code.  It provides macros and functions for accurate benchmarking and
+lightweight monitoring.  Furthermore, it provides predefined benchmarks to
+determine the cost of certain actions on a given platform and implementation.")
+      (license license:expat))))
+
+(define-public cl-the-cost-of-nothing
+  (sbcl-package->cl-source-package sbcl-the-cost-of-nothing))
+
+(define-public ecl-the-cost-of-nothing
+  (sbcl-package->ecl-package sbcl-the-cost-of-nothing))
+
+(define-public sbcl-atomichron
+  (let ((commit "5b3578bbad8c37ab559e56924d98c373efe11de5")
+        (revision "0"))
+    (package
+      (name "sbcl-atomichron")
+      (version (git-version "0.0.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/no-defun-allowed/atomichron")
+               (commit commit)))
+         (file-name (git-file-name "cl-atomichron" version))
+         (sha256
+          (base32 "1fmmhb3pbv7j4d1cc02zv24bpd0kd2agfjjcj46w3gmv1bb0hva1"))))
+      (build-system asdf-build-system/sbcl)
+      (inputs
+       (list sbcl-atomics sbcl-bordeaux-threads))
+      (home-page "https://github.com/no-defun-allowed/atomichron")
+      (synopsis "Atomic metering library for Common Lisp")
+      (description
+       "@code{atomichron} is a Common Lisp library which implements a time
+meter which tracks how many times a form is evaluated, and how long evaluation
+takes.  It uses atomic instructions so that meters will present correct
+results in the presence of multiple threads, while trying to minimize
+synchronization latency.")
+      (license license:bsd-2))))
+
+(define-public cl-atomichron
+  (sbcl-package->cl-source-package sbcl-atomichron))
+
+(define-public ecl-atomichron
+  (sbcl-package->ecl-package sbcl-atomichron))
+
 (define-public sbcl-glyphs
   (let ((commit "1ff5714e8c1dca327bc604dfe3e3d1f4b7755373"))
     (package
@@ -16499,6 +16966,35 @@ return the CPU count of the current system.")
 (define-public cl-cpus
   (sbcl-package->cl-source-package sbcl-cl-cpus))
 
+(define-public sbcl-system-load
+  (let ((commit "3ff1a40be55866cc5316ac7a530d872b12510294")
+        (revision "0"))
+    (package
+      (name "sbcl-system-load")
+      (version (git-version "1.0.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/Shinmera/system-load")
+               (commit commit)))
+         (file-name (git-file-name "cl-system-load" version))
+         (sha256
+          (base32 "08d8kr8j5l2m8p69f47iklxhna394vx9mrys0sgplf5f2bqb7xcv"))))
+      (build-system asdf-build-system/sbcl)
+      (home-page "https://github.com/Shinmera/system-load")
+      (synopsis "Access system's CPU and memory usage from Common Lisp")
+      (description
+       "System-Load is a Common Lisp library for accessing the system's CPU and
+memory usage.")
+      (license license:zlib))))
+
+(define-public cl-system-load
+  (sbcl-package->cl-source-package sbcl-system-load))
+
+(define-public ecl-system-load
+  (sbcl-package->ecl-package sbcl-system-load))
+
 (define-public sbcl-fof
   (let ((commit "522879e7da110ecf2e841998b197b34062c54b29")
         (revision "1"))
@@ -23666,6 +24162,38 @@ objects to be mixed and updated without manually defining many permutations.")
 (define-public ecl-dynamic-mixins
   (sbcl-package->ecl-package sbcl-dynamic-mixins))
 
+(define-public sbcl-stealth-mixin
+  (let ((commit "2f853fcead554221d4be3b10522b502ea729e944")
+        (revision "0"))
+    (package
+      (name "sbcl-stealth-mixin")
+      (version (git-version "0.0.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+               (url "https://github.com/robert-strandh/Stealth-mixin")
+               (commit commit)))
+         (file-name (git-file-name "cl-stealth-mixin" version))
+         (sha256
+          (base32 "0ar9cdmbmdnqz1ywpw34n47hlh0vqmb6pl76f5vbfgip3c81xwyi"))))
+      (build-system asdf-build-system/sbcl)
+      (inputs
+       (list sbcl-closer-mop))
+      (home-page "https://github.com/robert-strandh/Stealth-mixin")
+      (synopsis "Create stealth mixin classes")
+      (description
+       "Stealth-mixin is a Common Lisp library for creating stealth mixin
+classes.  These are classes that are dynamically mixed into other classes
+without the latter being aware of it.")
+      (license license:bsd-2))))
+
+(define-public cl-stealth-mixin
+  (sbcl-package->cl-source-package sbcl-stealth-mixin))
+
+(define-public ecl-stealth-mixin
+  (sbcl-package->ecl-package sbcl-stealth-mixin))
+
 (define-public sbcl-sealable-metaobjects
   (let ((commit "e09ec97252e0844528f61abdc0c7ee256875f8ee"))
     (package
@@ -24457,8 +24985,12 @@ between Lisp objects and some binary (i.e. octet-based) representation.")
          (sha256
           (base32 "1iri5wsp9sc1f5q934cj87zd79r5dc8fda0gl7x1pz95v0wx28yk"))))
       (build-system asdf-build-system/sbcl)
-      (native-inputs
-       (list sbcl-parachute))
+      (arguments
+       '(;; FIXME: Tests disabled because of a circular dependency between
+         ;; trivial-custom-debugger and parachute.
+         #:tests? #f))
+      ;;(native-inputs
+      ;; (list sbcl-parachute))
       (home-page "https://github.com/phoe/trivial-custom-debugger/")
       (synopsis "Allow arbitrary functions as the standard Lisp debugger")
       (description
diff --git a/gnu/packages/llvm.scm b/gnu/packages/llvm.scm
index f854493281..9ffdf8761b 100644
--- a/gnu/packages/llvm.scm
+++ b/gnu/packages/llvm.scm
@@ -563,11 +563,11 @@ output), and Binutils.")
 
 (define %llvm-monorepo-hashes
   '(("14.0.6" . "14f8nlvnmdkp9a9a79wv67jbmafvabczhah8rwnqrgd5g3hfxxxx")
-    ("15.0.4" . "0j5kx4s970qzcjr83kk6776zzjqfshl61x9fagqz8kjxcjbpg8cj")))
+    ("15.0.5" . "1z2szqlanksdmj91590wnxqav5z437mpasg00ghb610xkam2v34m")))
 
 (define %llvm-patches
   '(("14.0.6" . ("clang-14.0-libc-search-path.patch"))
-    ("15.0.4" . ("clang-15.0-libc-search-path.patch"))))
+    ("15.0.5" . ("clang-15.0-libc-search-path.patch"))))
 
 (define (llvm-monorepo version)
   (origin
@@ -583,7 +583,7 @@ output), and Binutils.")
 (define-public llvm-15
   (package
     (name "llvm")
-    (version "15.0.4")
+    (version "15.0.5")
     (source (llvm-monorepo version))
     (build-system cmake-build-system)
     (outputs '("out" "opt-viewer"))
@@ -740,7 +740,7 @@ of programming tools as well as libraries with equivalent functionality.")
                     (package-version llvm-15)))
      (sha256
       (base32
-       "03adxlh84if9p53m6izjsql500rjza9rng8akab2pdqibgrg73rh")))))
+       "0sa6si9v7ddsa9vmg6s3918xx969rvck2v1a0g7hb0fp9jk9j4r1")))))
 
 (define-public clang-14
   (clang-from-llvm
@@ -1522,7 +1522,7 @@ Library.")
 (define-public lld-15
   (package
     (name "lld")
-    (version "15.0.4")
+    (version (package-version llvm-15))
     (source (llvm-monorepo version))
     (build-system cmake-build-system)
     (inputs
@@ -1634,7 +1634,7 @@ misuse of libraries outside of the store.")))
 (define-public lldb
   (package
     (name "lldb")
-    (version "14.0.6")
+    (version (package-version llvm-15))
     (source (llvm-monorepo version))
     (build-system cmake-build-system)
     (arguments
@@ -1648,8 +1648,8 @@ misuse of libraries outside of the store.")))
     (native-inputs
      (list pkg-config swig))
     (inputs
-     (list clang-14
-           llvm-14
+     (list clang-15
+           llvm-15
            ;; Optional (but recommended) inputs.
            ncurses
            libedit
@@ -1668,7 +1668,7 @@ which highly leverage existing libraries in the larger LLVM project.")
 (define-public libcxx
   (package
     (name "libcxx")
-    (version "14.0.6")
+    (version (package-version llvm-15))
     (source (llvm-monorepo version))
     (build-system cmake-build-system)
     (arguments
diff --git a/gnu/packages/machine-learning.scm b/gnu/packages/machine-learning.scm
index 61b0400715..fbc06f96b6 100644
--- a/gnu/packages/machine-learning.scm
+++ b/gnu/packages/machine-learning.scm
@@ -3224,18 +3224,14 @@ Python.")
 (define-public python-hmmlearn
   (package
     (name "python-hmmlearn")
-    (version "0.2.6")
+    (version "0.2.7")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "hmmlearn" version))
        (sha256
         (base32
-         "1my0j3rzp17438idr32ssh0j969a98yjblx5igx5kgiiigr9qa1a"))
-       (snippet
-        #~(begin
-            (use-modules ((guix build utils)))
-            (delete-file "lib/hmmlearn/_hmmc.c")))))
+         "1qgnf1kdxicygy8nvpv866iqvwq0rc6xkd3s6slmvxvsy8h2fjvb"))))
     (build-system python-build-system)
     (arguments
      `(#:phases
@@ -3247,7 +3243,11 @@ Python.")
                (with-directory-excursion (string-append (assoc-ref outputs "out") "/lib")
                  (invoke "python" "-m" "pytest"))))))))
     (propagated-inputs
-     (list python-cython python-numpy python-scikit-learn python-scipy
+     (list pybind11
+           python-cython
+           python-numpy
+           python-scikit-learn
+           python-scipy
            python-setuptools-scm))
     (native-inputs
      (list python-pytest))
diff --git a/gnu/packages/mail.scm b/gnu/packages/mail.scm
index 414308d9fe..dc9fed90eb 100644
--- a/gnu/packages/mail.scm
+++ b/gnu/packages/mail.scm
@@ -4557,7 +4557,7 @@ databases, and other tools to process Outlook email archives.")
     (build-system gnu-build-system)
     (arguments
      `(#:tests? #f                      ;no tests
-       #:make-flags `((string-append "CC=" ,(cc-for-target)))
+       #:make-flags (list (string-append "CC=" ,(cc-for-target)))
        #:phases
        (modify-phases %standard-phases
          (delete 'configure)            ;no configure script
diff --git a/gnu/packages/mate.scm b/gnu/packages/mate.scm
index 03dfabc135..ce62366985 100644
--- a/gnu/packages/mate.scm
+++ b/gnu/packages/mate.scm
@@ -1490,48 +1490,51 @@ used to bring up authentication dialogs.")
     (native-inputs (list desktop-file-utils))
     (inputs
      ;; TODO: Add more packages
-     `(("at-spi2-core"              ,at-spi2-core)
-       ("atril"                     ,atril)
-       ("caja"                      ,caja)
-       ("dbus"                      ,dbus)
-       ("dconf"                     ,dconf)
-       ("engrampa"                  ,engrampa)
-       ("eom"                       ,eom)
-       ("font-abattis-cantarell"            ,font-abattis-cantarell)
-       ("glib-networking"           ,glib-networking)
-       ("gnome-keyring"             ,gnome-keyring)
-       ("gvfs"                      ,gvfs)
-       ("hicolor-icon-theme"        ,hicolor-icon-theme)
-       ("libmatekbd"                ,libmatekbd)
-       ("libmateweather"            ,libmateweather)
-       ("libmatemixer"              ,libmatemixer)
-       ("marco"                     ,marco)
-       ("mate-session-manager"      ,mate-session-manager)
-       ("mate-settings-daemon"      ,mate-settings-daemon)
-       ("mate-desktop"              ,mate-desktop)
-       ("mate-terminal"             ,mate-terminal)
-       ("mate-themes"               ,mate-themes)
-       ("mate-icon-theme"           ,mate-icon-theme)
-       ("mate-power-manager"        ,mate-power-manager)
-       ("mate-menu"                 ,mate-menus)
-       ("mate-panel"                ,mate-panel)
-       ("mate-control-center"       ,mate-control-center)
-       ("mate-media"                ,mate-media)
-       ("mate-applets"              ,mate-applets)
-       ("mate-user-guide"           ,mate-user-guide)
-       ("mate-calc"                 ,mate-calc)
-       ("mate-backgrounds"          ,mate-backgrounds)
-       ("mate-netbook"              ,mate-netbook)
-       ("mate-utils"                ,mate-utils)
-       ("mate-polkit"               ,mate-polkit)
-       ("mate-system-monitor"       ,mate-system-monitor)
-       ("mate-utils"                ,mate-utils)
-       ("pluma"                     ,pluma)
-       ("pinentry-gnome3"           ,pinentry-gnome3)
-       ("pulseaudio"                ,pulseaudio)
-       ("shared-mime-info"          ,shared-mime-info)
-       ("yelp"                      ,yelp)
-       ("zenity"                    ,zenity)))
+     (append (if (or (%current-target-system)
+                     (supported-package? gnome-keyring))
+                 (list gnome-keyring)
+                 '())
+             (list at-spi2-core
+                   atril
+                   caja
+                   dbus
+                   dconf
+                   engrampa
+                   eom
+                   font-abattis-cantarell
+                   glib-networking
+                   gvfs
+                   hicolor-icon-theme
+                   libmatekbd
+                   libmateweather
+                   libmatemixer
+                   marco
+                   mate-session-manager
+                   mate-settings-daemon
+                   mate-desktop
+                   mate-terminal
+                   mate-themes
+                   mate-icon-theme
+                   mate-power-manager
+                   mate-menus
+                   mate-panel
+                   mate-control-center
+                   mate-media
+                   mate-applets
+                   mate-user-guide
+                   mate-calc
+                   mate-backgrounds
+                   mate-netbook
+                   mate-utils
+                   mate-polkit
+                   mate-system-monitor
+                   mate-utils
+                   pluma
+                   pinentry-gnome3
+                   pulseaudio
+                   shared-mime-info
+                   yelp
+                   zenity)))
     (propagated-inputs
      ;; Default font that applications such as IceCat require.
      (list font-dejavu))
diff --git a/gnu/packages/maths.scm b/gnu/packages/maths.scm
index 975d764a2a..531e3f0324 100644
--- a/gnu/packages/maths.scm
+++ b/gnu/packages/maths.scm
@@ -55,6 +55,8 @@
 ;;; Copyright © 2022 Philip McGrath <philip@philipmcgrath.com>
 ;;; Copyright © 2022 Marek Felšöci <marek@felsoci.sk>
 ;;; Copyright © 2022 vicvbcun <guix@ikherbers.com>
+;;; Copyright © 2022 Liliana Marie Prikler <liliana.prikler@gmail.com>
+;;; Copyright © 2022 Maximilian Heisinger <mail@maxheisinger.at>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -158,6 +160,7 @@
   #:use-module (gnu packages serialization)
   #:use-module (gnu packages shells)
   #:use-module (gnu packages sphinx)
+  #:use-module (gnu packages sqlite)
   #:use-module (gnu packages swig)
   #:use-module (gnu packages tcl)
   #:use-module (gnu packages texinfo)
@@ -894,20 +897,6 @@ large scale eigenvalue problems.")
     (license (license:non-copyleft "file://COPYING"
                                 "See COPYING in the distribution."))))
 
-(define-public arpack-ng-3.3.0
-  (package
-    (inherit arpack-ng)
-    (version "3.3.0")
-    (source
-     (origin
-       (method git-fetch)
-       (uri (git-reference (url (package-home-page arpack-ng))
-                           (commit version)))
-       (file-name (git-file-name (package-name arpack-ng) version))
-       (sha256
-        (base32
-         "00h6bjvxjq7bv0b8pwnc0gw33ns6brlqv00xx2rh3w9b5n205918"))))))
-
 (define-public arpack-ng-openmpi
   (package (inherit arpack-ng)
     (name "arpack-ng-openmpi")
@@ -2556,7 +2545,7 @@ between aspif and smodels format or to a human-readable text format.")
 (define-public clasp
   (package
     (name "clasp")
-    (version "3.3.6")
+    (version "3.3.9")
     (source (origin
               (method git-fetch)
               (uri (git-reference
@@ -2565,7 +2554,7 @@ between aspif and smodels format or to a human-readable text format.")
               (file-name (git-file-name name version))
               (sha256
                (base32
-                "0rahqiq530jckvx717858h1q5p8znp1kb6sjm95p8blkr4n3pvmj"))))
+                "163ps9zq7xppqy9hj5qnw6z5lcjnm4xf5fwjsavpia5ynm3hngcw"))))
     (build-system cmake-build-system)
     (arguments
      `(#:configure-flags '("-DCLASP_BUILD_TESTS=on"
@@ -2761,7 +2750,7 @@ can solve two kinds of problems:
 (define-public octave-cli
   (package
     (name "octave-cli")
-    (version "7.1.0")
+    (version "7.2.0")
     (source
      (origin
       (method url-fetch)
@@ -2769,7 +2758,7 @@ can solve two kinds of problems:
                           version ".tar.xz"))
       (sha256
        (base32
-        "0wv26nsfi6cq80np6p4av4wfrvbaflca6szajf6c60mbpdg63m1z"))))
+        "0w81ncl9d4x1ay3ylsag87k20c0byiyjcmfd9kb7b7ylr71pivsa"))))
     (build-system gnu-build-system)
     (inputs
      `(("alsa-lib" ,alsa-lib)
@@ -2937,7 +2926,7 @@ Open CASCADE library.")
 (define-public opencascade-occt
   (package
     (name "opencascade-occt")
-    (version "7.6.0")
+    (version "7.6.2")
     (source
       (origin
         (method git-fetch)
@@ -2949,7 +2938,7 @@ Open CASCADE library.")
                                           version)))))
         (file-name (git-file-name name version))
         (sha256
-         (base32 "1rcwm9fkx0j4wrsyikb6g7qd611kpry7dand5dzdjvs5vzd13zvd"))
+         (base32 "07z5d83vm9f50an7vhimzl7gbmri1dn6p2g999l5fgyaj5sg5f02"))
         (modules '((guix build utils)))
         (snippet
          '(begin
@@ -4874,7 +4863,7 @@ Fresnel integrals, and similar related functions as well.")
 (define-public suitesparse
   (package
     (name "suitesparse")
-    (version "5.12.0")
+    (version "5.13.0")
     (source
      (origin
        (method git-fetch)
@@ -4884,7 +4873,7 @@ Fresnel integrals, and similar related functions as well.")
        (file-name (git-file-name name version))
        (sha256
         (base32
-         "0zpl51pfpv7ap7z97jlryba2la1qdmzm11bhzkn55wlb03xzi6k6"))
+         "1zwri246yr39p9ymjp18dzv36ch0dn107sf0jghj7capigasfxq2"))
        (patches (search-patches "suitesparse-mongoose-cmake.patch"))
        (modules '((guix build utils)))
        (snippet
@@ -6825,7 +6814,7 @@ assemble global function spaces on finite-element grids.")
                   "doc/dune-grid/grids/gridfactory/testgrids"))
                #t))
            (add-after 'build 'build-tests
-             (lambda* (#:key make-flags parallel-build? #:allow-other-keys)
+             (lambda* (#:key inputs make-flags parallel-build? #:allow-other-keys)
                (setenv "CPLUS_INCLUDE_PATH"
                        (string-append (assoc-ref inputs "dune-grid") "/share"))
                (apply invoke "make" "build_tests"
@@ -7376,6 +7365,221 @@ back to C with improved data structures, better scheduling of inprocessing and
 optimized algorithms and implementation.")
     (license license:expat)))
 
+(define-public aiger
+  (package
+    (name "aiger")
+    (version "1.9.9")
+    (source (origin
+             (method url-fetch)
+             (uri (string-append "http://fmv.jku.at/aiger/aiger-"
+                                 version ".tar.gz"))
+             (sha256
+               (base32
+                "1ish0dw0nf9gyghxsdhpy1jjiy5wp54c993swp85xp7m6vdx6l0y"))))
+    (outputs (list "out" "static"))
+    (build-system gnu-build-system)
+    (arguments
+     (list #:tests? #f                  ; no check target
+           #:phases
+           #~(modify-phases %standard-phases
+               (add-after 'unpack 'patch-source
+                 (lambda* (#:key inputs #:allow-other-keys)
+                   (substitute* "aiger.c"
+                     (("\"(gzip|gunzip)" all cmd)
+                      (string-append
+                       "\""
+                       (search-input-file inputs (string-append "bin/" cmd)))))))
+               (add-after 'unpack 'patch-build-files
+                 (lambda* (#:key outputs #:allow-other-keys)
+                   (substitute* "makefile.in"
+                     (("test -d .*") "true")
+                     (("/usr/local") (assoc-ref outputs "out")))))
+               (replace 'configure
+                 (lambda* (#:key configure-flags #:allow-other-keys)
+                   (apply invoke "./configure.sh" configure-flags)))
+               (add-after 'install 'install-static
+                 (lambda* (#:key outputs #:allow-other-keys)
+                   (apply invoke #$(ar-for-target) "rcs" "libaiger.a"
+                          (find-files "." "\\.o$"))
+                   (let* ((static (assoc-ref outputs "static"))
+                          (lib (string-append static "/lib"))
+                          (incl (string-append static "/include/aiger")))
+                     (mkdir-p lib)
+                     (mkdir-p incl)
+                     (install-file "libaiger.a" lib)
+                     (for-each (lambda (f) (install-file f incl))
+                               (find-files "." "\\.h$"))))))))
+    (inputs (list gzip))
+    (home-page "http://fmv.jku.at/aiger")
+    (synopsis "Utilities for And-Inverter Graphs")
+    (description "AIGER is a format, library and set of utilities for
+@acronym{AIG, And-Inverter Graphs}s.  The focus is on conversion utilities and a
+generic reader and writer API.")
+    (license (list license:expat
+                   license:bsd-3))))    ; blif2aig
+
+(define-public lingeling
+  (let ((commit "72d2b13eea5fbd95557a3d0d199cd98dfbdc76ee")
+        (revision "1"))
+    (package
+     (name "lingeling")
+     (version (git-version "sc2022" revision commit))
+     (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/arminbiere/lingeling")
+                    (commit commit)))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "16s30x8s2cw6icchwm65zj56ph4qwz6i07g3hwkknvajisvjq85c"))))
+     (build-system gnu-build-system)
+     (arguments
+      (list #:test-target "test"
+            #:modules `((ice-9 match)
+                        ,@%gnu-build-system-modules)
+            #:configure-flags #~(list "--aiger=.")
+            #:phases
+            #~(modify-phases %standard-phases
+                (add-after 'unpack 'unpack-aiger
+                  (lambda* (#:key inputs #:allow-other-keys)
+                    (invoke #$(ar-for-target) "x"
+                            (search-input-file inputs "lib/libaiger.a")
+                            "aiger.o")
+                    (copy-file
+                     (search-input-file inputs "include/aiger/aiger.h")
+                     "aiger.h")))
+                (add-after 'unpack 'hard-code-commit
+                  (lambda _
+                    (substitute* "mkconfig.sh"
+                      (("`\\./getgitid`") #$commit))))
+                (add-after 'unpack 'patch-source
+                  (lambda* (#:key inputs #:allow-other-keys)
+                    (substitute* (list "treengeling.c" "lgldimacs.c")
+                      (("\"(gunzip|xz|bzcat|7z)" all cmd)
+                       (string-append
+                        "\""
+                        (search-input-file inputs (string-append "bin/" cmd)))))))
+                (replace 'configure
+                  (lambda* (#:key configure-flags #:allow-other-keys)
+                    (apply invoke "./configure.sh" configure-flags)))
+                (replace 'install
+                  (lambda* (#:key outputs #:allow-other-keys)
+                    (let ((bin (string-append (assoc-ref outputs "out")
+                                              "/bin")))
+                      (mkdir-p bin)
+                      (for-each
+                       (lambda (file)
+                         (install-file file bin))
+                       '("blimc" "ilingeling" "lglddtrace" "lglmbt"
+                         "lgluntrace" "lingeling" "plingeling"
+                         "treengeling")))))
+                (add-after 'install 'wrap-path
+                  (lambda* (#:key outputs #:allow-other-keys)
+                    (with-directory-excursion (string-append
+                                               (assoc-ref outputs "out")
+                                               "/bin")
+                      (for-each
+                       (lambda (file)
+                         (wrap-program
+                          file
+                          '("PATH" suffix
+                            #$(map (lambda (input)
+                                     (file-append (this-package-input input) "/bin"))
+                                   '("gzip" "bzip2" "xz" "p7zip")))))
+                       ;; These programs use sprintf on buffers with magic
+                       ;; values to construct commands (yes, eww), so we
+                       ;; can't easily substitute* them.
+                       '("lglddtrace" "lgluntrace" "lingeling" "plingeling"))))))))
+     (inputs (list `(,aiger "static") gzip bzip2 xz p7zip))
+     (home-page "http://fmv.jku.at/lingeling")
+     (synopsis "SAT solver")
+     (description "This package provides a range of SAT solvers, including
+the sequential @command{lingeling} and its parallel variants
+@command{plingeling} and @command{treengeling}.  A bounded model checker is
+also included.")
+     (license license:expat))))
+
+(define-public louvain-community
+  (let ((commit "8cc5382d4844af127b1c1257373740d7e6b76f1e")
+        (revision "1"))
+    (package
+      (name "louvain-community")
+      (version (git-version "1.0.0" revision commit))
+      (source (origin
+                (method git-fetch)
+                (uri (git-reference
+                       (url "https://github.com/meelgroup/louvain-community")
+                       (commit commit)))
+                (file-name (git-file-name name version))
+                (sha256
+                 (base32
+                  "1ss00hkdvr9bdkd355hxf8zd7xycb3nm8qpy7s75gjjf6yng0bfj"))))
+      (build-system cmake-build-system)
+      (arguments
+       (list #:tests? #f                ; tests appear to require missing files
+             #:phases
+             #~(modify-phases %standard-phases
+                 (add-after 'unpack 'encode-git-hash
+                   (lambda _
+                     (substitute* "CMakeLists.txt"
+                       (("GIT-hash-notfound") #$commit)))))))
+      (native-inputs (list python))
+      (home-page "https://github.com/meelgroup/louvain-communities")
+      (synopsis "Multi-criteria community detection")
+      (description "This package provides a C++ implementation of the Louvain
+community detection algorithm.")
+      (license license:lgpl3+))))
+
+(define-public cryptominisat
+  (package
+    (name "cryptominisat")
+    (version "5.11.4")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/msoos/cryptominisat")
+             (commit version)))
+      (file-name (git-file-name name version))
+      (sha256
+       (base32
+        "1izjn44phjp9670s7bxrdx4p0r59idqwv3bm6sr0qnlqlha5z4zc"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list
+      #:build-type "Release"
+      #:test-target "test"
+      #:configure-flags #~(list "-DENABLE_TESTING=ON" "-DSTATS=ON")
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'patch-source
+            (lambda* (#:key inputs #:allow-other-keys)
+              (substitute* "CMakeLists.txt"
+                (("add_subdirectory\\(utils/lingeling-ala\\)") ""))
+              ;; Transitively included in vendored gtest.h. Fixed in
+              ;; upstream:
+              ;; https://github.com/msoos/cryptominisat/pull/686
+              (substitute* "tests/assump_test.cpp"
+                (("#include <vector>")
+                 "#include <vector>\n#include <algorithm>"))
+              (substitute* "tests/CMakeLists.txt"
+                (("add_subdirectory\\(\\$\\{GTEST_PREFIX\\} gtest\\)")
+                 "find_package(GTest REQUIRED)")
+                (("add_subdirectory\\(\\$\\{PROJECT_SOURCE_DIR\\}/utils/.*\\)")
+                 "")))))))
+    (inputs (list boost louvain-community python python-numpy sqlite zlib))
+    (native-inputs (list googletest lingeling python python-wrapper python-lit))
+    (synopsis "Incremental SAT solver")
+    (description
+     "CryptoMiniSat is an incremental SAT solver with both command line and
+library (C++, C, Python) interfaces.  The command-line interface takes a
+@acronym{CNF, Conjunctive Normal Form} as an input in the DIMACS format with
+the extension of XOR clauses.  The library interfaces mimic this and also
+allow incremental solving, including assumptions.")
+    (home-page "https://github.com/msoos/cryptominisat")
+    (license license:expat)))
+
 (define-public libqalculate
   (package
     (name "libqalculate")
diff --git a/gnu/packages/mpd.scm b/gnu/packages/mpd.scm
index 4e9cb0cb37..cd37d4682c 100644
--- a/gnu/packages/mpd.scm
+++ b/gnu/packages/mpd.scm
@@ -48,6 +48,7 @@
   #:use-module (gnu packages boost)
   #:use-module (gnu packages cdrom)
   #:use-module (gnu packages cmake) ;for MPD
+  #:use-module (gnu packages cpp)
   #:use-module (gnu packages freedesktop) ;elogind
   #:use-module (gnu packages gettext)
   #:use-module (gnu packages gnome)
@@ -55,6 +56,7 @@
   #:use-module (gnu packages gtk)
   #:use-module (gnu packages icu4c)
   #:use-module (gnu packages libusb)
+  #:use-module (gnu packages lua)
   #:use-module (gnu packages readline)
   #:use-module (gnu packages check)
   #:use-module (gnu packages compression)
@@ -66,15 +68,19 @@
   #:use-module (gnu packages music)
   #:use-module (gnu packages ncurses)
   #:use-module (gnu packages pcre)
+  #:use-module (gnu packages perl)
   #:use-module (gnu packages pkg-config)
   #:use-module (gnu packages pretty-print)
   #:use-module (gnu packages python)
   #:use-module (gnu packages python-xyz)
   #:use-module (gnu packages pulseaudio)
   #:use-module (gnu packages qt)
+  #:use-module (gnu packages serialization)
   #:use-module (gnu packages sphinx)
   #:use-module (gnu packages sqlite)
+  #:use-module (gnu packages tls)
   #:use-module (gnu packages video)
+  #:use-module (gnu packages web)
   #:use-module (gnu packages xiph))
 
 (define-public libmpdclient
@@ -380,7 +386,7 @@ MPD servers, search and multimedia key support.")
 (define-public ashuffle
   (package
     (name "ashuffle")
-    (version "2.0.2")
+    (version "3.13.4")
     (source (origin
               (method git-fetch)
               (uri (git-reference
@@ -389,10 +395,20 @@ MPD servers, search and multimedia key support.")
               (file-name (git-file-name name version))
               (sha256
                (base32
-                "11aa95cg0yca2m2d00sar6wr14g3lc7cfm9bin1h7lk7asdm8azp"))))
+                "09dvar0aglyy2h9y115ymgryd8l6npc2y2ccdzij0b70f47ncqmf"))))
     (native-inputs (list pkg-config))
-    (inputs (list libmpdclient))
+    (inputs
+     (list abseil-cpp-cxxstd17
+           googletest
+           libmpdclient
+           yaml-cpp))
     (build-system meson-build-system)
+    (arguments
+     (list #:configure-flags
+           #~'("-Dtests=enabled"
+               "-Dunsupported_use_system_absl=true"
+               "-Dunsupported_use_system_gtest=true"
+               "-Dunsupported_use_system_yamlcpp=true")))
     (home-page "https://github.com/joshkunz/ashuffle")
     (synopsis "Automatic library-wide shuffle for mpd")
     (description "ashuffle is an application for automatically shuffling your
@@ -561,3 +577,27 @@ which is focused on playing local music without the need of managing playlists.
 Instead of maintaining a client side database of your music library,
 mpdevil loads all tags and covers on demand.")
     (license license:gpl3+)))
+
+(define-public mympd
+  (package
+    (name "mympd")
+    (version "10.1.2")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/jcorporation/myMPD")
+                    (commit (string-append "v" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "1cqq09j7mi7dz5y6l7i0sa6vi2n5zrndnrxnqsi4vcg99fc2vwv8"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list #:tests? #f)) ; no test target
+    (native-inputs (list jq perl))
+    (inputs (list flac libid3tag lua openssl pcre2))
+    (home-page "https://jcorporation.github.io/")
+    (synopsis "Web-based MPD client")
+    (description "MyMPD is a mobile-friendly web client for the MPD music
+player daemon.")
+    (license license:gpl3+)))
diff --git a/gnu/packages/music.scm b/gnu/packages/music.scm
index 9826a36034..15f564a35d 100644
--- a/gnu/packages/music.scm
+++ b/gnu/packages/music.scm
@@ -1,6 +1,6 @@
 ;;; GNU Guix --- Functional package management for GNU
 ;;; Copyright © 2014, 2019 Eric Bavier <bavier@member.fsf.org>
-;;; Copyright © 2015, 2016, 2017, 2018, 2019, 2020, 2021 Ricardo Wurmus <rekado@elephly.net>
+;;; Copyright © 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022 Ricardo Wurmus <rekado@elephly.net>
 ;;; Copyright © 2015 Paul van der Walt <paul@denknerd.org>
 ;;; Copyright © 2016 Al McElrath <hello@yrns.org>
 ;;; Copyright © 2016, 2017, 2019, 2021, 2022 Efraim Flashner <efraim@flashner.co.il>
@@ -1910,7 +1910,7 @@ with a selectable pattern matrix size.")
   (package
     (inherit bsequencer)
     (name "bchoppr")
-    (version "1.10.10")
+    (version "1.12.0")
     (source
      (origin
        (method git-fetch)
@@ -1919,7 +1919,7 @@ with a selectable pattern matrix size.")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "0gxz0cpxdfj7ajcd9yg05d26i7p24mx5865vy3ph76ni8kycdlrc"))))
+        (base32 "1jfp98qa0frmdybrg71fn8wxn1b3ginkbkcg9cz9y83j1m0jqrif"))))
     (synopsis "Audio stream-chopping LV2 plugin")
     (description "B.Choppr cuts the audio input stream into a repeated
 sequence of up to 16 chops.  Each chop can be leveled up or down (gating).
@@ -2300,10 +2300,10 @@ perform creative live mixes with digital music files.")
            alsa-lib
            new-session-manager
            liblo
-           qtbase-5
-           qtsvg-5))
+           qtbase
+           qtsvg))
     (native-inputs
-     (list pkg-config qttools-5))
+     (list pkg-config qttools))
     (home-page "https://synthv1.sourceforge.io")
     (synopsis "Polyphonic subtractive synthesizer")
     (description
@@ -2333,10 +2333,10 @@ oscillators and stereo effects.")
            alsa-lib
            new-session-manager
            liblo
-           qtbase-5
-           qtsvg-5))
+           qtbase
+           qtsvg))
     (native-inputs
-     (list pkg-config qttools-5))
+     (list pkg-config qttools))
     (home-page "https://drumkv1.sourceforge.io")
     (synopsis "Drum-kit sampler synthesizer with stereo effects")
     (description
@@ -2366,10 +2366,10 @@ effects.")
            alsa-lib
            new-session-manager
            liblo
-           qtbase-5
-           qtsvg-5))
+           qtbase
+           qtsvg))
     (native-inputs
-     (list pkg-config qttools-5))
+     (list pkg-config qttools))
     (home-page "https://samplv1.sourceforge.io")
     (synopsis "Polyphonic sampler synthesizer with stereo effects")
     (description
@@ -2399,10 +2399,10 @@ effects.")
            new-session-manager
            liblo
            fftwf
-           qtbase-5
-           qtsvg-5))
+           qtbase
+           qtsvg))
     (native-inputs
-     (list pkg-config qttools-5))
+     (list pkg-config qttools))
     (home-page "https://padthv1.sourceforge.io")
     (synopsis "Polyphonic additive synthesizer")
     (description
@@ -3313,14 +3313,13 @@ from the command line.")
            libvorbis
            lilv
            lv2
-           qtbase-5
-           qtsvg-5
-           qtx11extras
+           qtbase
+           qtsvg
            rubberband
            suil
            zlib))
     (native-inputs
-     (list pkg-config qttools-5))
+     (list pkg-config qttools))
     (home-page "https://qtractor.org/")
     (synopsis "Audio/MIDI multi-track sequencer")
     (description
diff --git a/gnu/packages/networking.scm b/gnu/packages/networking.scm
index 3f44d082fb..f5276e330e 100644
--- a/gnu/packages/networking.scm
+++ b/gnu/packages/networking.scm
@@ -593,7 +593,7 @@ supported, including rtmp://, rtmpt://, rtmpe://, rtmpte://, and rtmps://.")
 (define-public slurm-monitor
   (package
     (name "slurm-monitor")
-    (version "0.4.3")
+    (version "0.4.4")
     (source
      (origin
        (method git-fetch)
@@ -603,9 +603,10 @@ supported, including rtmp://, rtmpt://, rtmpe://, rtmpte://, and rtmps://.")
          (commit (string-append "upstream/" version))))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "1n6pgrcs8gwrcq5fch1q3yk3jipjwrf21s9a13fbjrl903g5zzv9"))))
-    (build-system cmake-build-system)
+        (base32 "07q8895bxsajkwip8dgrrwr1m8a10xnl4p0g6wqcrd2wf4hx5gn3"))))
+    (build-system meson-build-system)
     (arguments `(#:tests? #f)) ;no tests
+    (native-inputs (list pkg-config))
     (inputs (list ncurses))
     (synopsis "Network load monitor")
     (description
@@ -1538,22 +1539,14 @@ Ethernet devices.")
 (define-public ifstatus
   (package
     (name "ifstatus")
-    (version "1.1.0")
+    (version "2.0.0")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://sourceforge/ifstatus/ifstatus/"
-                                  "ifstatus%20v" version "/ifstatus-v"
-                                  version ".tar.gz"))
+                                  "ifstatus-v" version ".tar.gz"))
               (sha256
                (base32
-                "045cbsq9ps32j24v8y5hpyqxnqn9mpaf3mgvirlhgpqyb9jsia0c"))
-              (modules '((guix build utils)))
-              (snippet
-               '(begin
-                  (substitute* "Main.h"
-                    (("#include <stdio.h>")
-                     "#include <stdio.h>\n#include <stdlib.h>"))
-                  #t))))
+                "0n622f2m3x901hcmad4ns52r2x75csy4nqraagzb8h9fn0j62jkv"))))
     (build-system gnu-build-system)
     (arguments
      '(#:tests? #f                                ; no "check" target
diff --git a/gnu/packages/nickle.scm b/gnu/packages/nickle.scm
index 95b9915414..6b69d7cb92 100644
--- a/gnu/packages/nickle.scm
+++ b/gnu/packages/nickle.scm
@@ -28,14 +28,14 @@
 (define-public nickle
   (package
     (name "nickle")
-    (version "2.82")
+    (version "2.90")
     (source (origin
               (method url-fetch)
               (uri (string-append "https://nickle.org/release/nickle-"
                                   version ".tar.gz"))
               (sha256
                (base32
-                "0jy96z01qbrnmsrywn5mfa14615qdix6b8520qd65c6yjyrk8gs0"))))
+                "197532b7ghkfnzx9qvxd2qjpnqba7bfl79iff3hk2jxcl0d83czv"))))
     (build-system gnu-build-system)
     (native-inputs
      (list readline))
diff --git a/gnu/packages/password-utils.scm b/gnu/packages/password-utils.scm
index c74ffe5242..3248e06d8f 100644
--- a/gnu/packages/password-utils.scm
+++ b/gnu/packages/password-utils.scm
@@ -1455,3 +1455,43 @@ are not using it.  It uses the same GPG key to encrypt passwords and tomb,
 therefore you don't need to manage more key or secret.  Moreover, you can ask
 pass-tomb to automatically close your store after a given time.")
     (license license:gpl3+)))
+
+(define-public xkcdpass
+  (package
+    (name "xkcdpass")
+    (version "1.19.3")
+    (home-page "https://github.com/redacted/XKCD-password-generator")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url home-page)
+                    (commit (string-append "xkcdpass-" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "0xfrmx9k2vinlagv476rfcfdp41aix1ldy6qnzzx26n985gcyk7p"))))
+    (build-system python-build-system)
+    (arguments
+     `(#:phases
+       (modify-phases %standard-phases
+         (add-after 'install 'install-manpage
+           (lambda* (#:key outputs #:allow-other-keys)
+             (install-file
+              "xkcdpass.1"
+              (string-append (assoc-ref outputs "out") "/share/man/man1")))))))
+    (synopsis
+     "Generate secure multiword passwords/passphrases, inspired by XKCD")
+    (description
+     "This package provides a flexible and scriptable password generator which
+generates strong passphrases, inspired by
+@url{https://xkcd.com/936/,XKCD 936}.")
+    (license (list license:bsd-3 ;code
+                   license:cc0 ;spanish, eff_large_de, french word lists
+                   license:cc-by-sa3.0 ;finnish, italian word list
+                   license:cc-by-sa4.0 ;norwegian word list
+                   license:eupl1.1 ;finnish word list
+                   license:gpl2 ;portuguese word list
+                   license:gpl3 ;ger-anix word list
+                   license:lgpl2.0 ;finnish word list
+                   license:lgpl2.1 ;portuguese word list
+                   license:mpl1.1)))) ;portuguese word list
diff --git a/gnu/packages/patches/ecl-16-format-directive-limit.patch b/gnu/packages/patches/ecl-16-format-directive-limit.patch
deleted file mode 100644
index 237db92722..0000000000
--- a/gnu/packages/patches/ecl-16-format-directive-limit.patch
+++ /dev/null
@@ -1,83 +0,0 @@
-Patch backported by Sage.
-
-Fix from upstream that happens to work around
-https://trac.sagemath.org/ticket/23011
-diff --git a/src/lsp/format.lsp b/src/lsp/format.lsp
-index 77ca799..53b887c 100644
---- a/src/lsp/format.lsp
-+++ b/src/lsp/format.lsp
-@@ -307,11 +307,13 @@
-                   :start (format-directive-start struct)
-                   :end (format-directive-end struct))))
- 
-+(defconstant +format-directive-limit+ (1+ (char-code #\~)))
-+
- #+formatter
- (defparameter *format-directive-expanders*
--  (make-array char-code-limit :initial-element nil))
-+  (make-array +format-directive-limit+ :initial-element nil))
- (defparameter *format-directive-interpreters*
--  (make-array char-code-limit :initial-element nil))
-+  (make-array +format-directive-limit+ :initial-element nil))
- 
- (defparameter *default-format-error-control-string* nil)
- (defparameter *default-format-error-offset* nil)
-@@ -550,24 +552,24 @@
-            (write-string directive stream)
-            (interpret-directive-list stream (cdr directives) orig-args args))
-           (#-ecl format-directive #+ecl vector
-+           (multiple-value-bind
-+                 (new-directives new-args)
-+               (let* ((code (char-code (format-directive-character directive)))
-+                      (function
-+                        (and (< code +format-directive-limit+)
-+                             (svref *format-directive-interpreters* code)))
-+                      (*default-format-error-offset*
-+                        (1- (format-directive-end directive))))
-+                 (unless function
-+                   (error 'format-error
-+                          :complaint "Unknown format directive."))
-                  (multiple-value-bind
-                        (new-directives new-args)
--                     (let ((function
--                            (svref *format-directive-interpreters*
--                                   (char-code (format-directive-character
--                                               directive))))
--                           (*default-format-error-offset*
--                            (1- (format-directive-end directive))))
--                       (unless function
--                         (error 'format-error
--                                :complaint "Unknown format directive."))
--                       (multiple-value-bind
--                             (new-directives new-args)
--                           (funcall function stream directive
--                                    (cdr directives) orig-args args)
--                         (values new-directives new-args)))
--                   (interpret-directive-list stream new-directives
--                                             orig-args new-args)))))
-+                     (funcall function stream directive
-+                              (cdr directives) orig-args args)
-+                   (values new-directives new-args)))
-+             (interpret-directive-list stream new-directives
-+                                       orig-args new-args)))))
-       args))
- 
- 
-@@ -639,11 +641,12 @@
-        (values `(write-string ,directive stream)
-                more-directives))
-       (format-directive
--       (let ((expander
--              (aref *format-directive-expanders*
--                    (char-code (format-directive-character directive))))
--             (*default-format-error-offset*
--              (1- (format-directive-end directive))))
-+       (let* ((code (char-code (format-directive-character directive)))
-+              (expander
-+                (and (< code +format-directive-limit+)
-+                     (svref *format-directive-expanders* code)))
-+              (*default-format-error-offset*
-+                (1- (format-directive-end directive))))
-          (if expander
-              (funcall expander directive more-directives)
-              (error 'format-error
diff --git a/gnu/packages/patches/ecl-16-ignore-stderr-write-error.patch b/gnu/packages/patches/ecl-16-ignore-stderr-write-error.patch
deleted file mode 100644
index 42d213c0e9..0000000000
--- a/gnu/packages/patches/ecl-16-ignore-stderr-write-error.patch
+++ /dev/null
@@ -1,17 +0,0 @@
-Patch adapted from Sage.
-diff -Naur ecl-16.1.2.orig/src/c/file.d ecl-16.1.2/src/c/file.d
---- ecl-16.1.2.orig/src/c/file.d	2016-05-11 13:10:51.867673867 +1200
-+++ ecl-16.1.2/src/c/file.d	2016-05-11 14:44:48.121907307 +1200
-@@ -3354,8 +3354,10 @@
-   ecl_disable_interrupts();
-   do {
-     out = fwrite(c, sizeof(char), n, IO_STREAM_FILE(strm));
--  } while (out < n && restartable_io_error(strm, "fwrite"));
--  ecl_enable_interrupts();
-+  /* Ignore write errors to stderr to avoid an infinite loop */
-+  } while (out < n && (IO_STREAM_FILE(strm) != stderr) && restartable_io_error(strm, "fwrite"));
-+
-+  ecl_enable_interrupts();
-   return out;
- }
- 
diff --git a/gnu/packages/patches/ecl-16-libffi.patch b/gnu/packages/patches/ecl-16-libffi.patch
deleted file mode 100644
index fc06a07606..0000000000
--- a/gnu/packages/patches/ecl-16-libffi.patch
+++ /dev/null
@@ -1,16 +0,0 @@
-Patch adapted from Sage. Allows building ECL on libffi 3.3.
-diff --git a/src/c/ffi.d b/src/c/ffi.d
-index 8861303e..8a959c23 100644
---- a/src/c/ffi.d
-+++ b/src/c/ffi.d
-@@ -133,8 +133,8 @@ static struct {
- #elif defined(X86_WIN64)
-   {@':win64', FFI_WIN64},
- #elif defined(X86_ANY) || defined(X86) || defined(X86_64)
--  {@':cdecl', FFI_SYSV},
--  {@':sysv', FFI_SYSV},
-+  {@':cdecl', FFI_UNIX64},
-+  {@':sysv', FFI_UNIX64},
-   {@':unix64', FFI_UNIX64},
- #endif
- };
diff --git a/gnu/packages/patches/kcontacts-incorrect-country-name.patch b/gnu/packages/patches/kcontacts-incorrect-country-name.patch
new file mode 100644
index 0000000000..7e15f9f5eb
--- /dev/null
+++ b/gnu/packages/patches/kcontacts-incorrect-country-name.patch
@@ -0,0 +1,85 @@
+From 5fc2ce8b9f34ea3218a030aeede01b70bedb2546 Mon Sep 17 00:00:00 2001
+From: Petr Hodina <phodina@protonmail.com>
+Date: Wed, 28 Sep 2022 20:58:43 +0200
+Subject: [PATCH] autotests: Fix incorrect name of country in comparison.
+
+
+diff --git a/autotests/addresstest.cpp b/autotests/addresstest.cpp
+index fc6a9bc7..01e474b6 100644
+--- a/autotests/addresstest.cpp
++++ b/autotests/addresstest.cpp
+@@ -157,7 +157,7 @@ void AddressTest::formatTest()
+ 
+         const QString result(
+             QStringLiteral("Jim Knopf\nLummerlandstr. 1\n"
+-                           "12345 Lummerstadt\n\nGERMANIA"));
++                           "12345 Lummerstadt\n\nGERMANY"));
+ 
+         QCOMPARE(address.formatted(KContacts::AddressFormatStyle::Postal, QStringLiteral("Jim Knopf")), result);
+ #if KCONTACTS_BUILD_DEPRECATED_SINCE(5, 92)
+@@ -175,7 +175,7 @@ void AddressTest::formatTest()
+ 
+         const QString result(
+             QStringLiteral("Huck Finn\n457 Foobar Ave\nNERVOUSBREAKTOWN,"
+-                           " DC 1A2B3C\n\nSTATI UNITI"));
++                           " DC 1A2B3C\n\nUNITED STATES"));
+         QCOMPARE(address.formatted(KContacts::AddressFormatStyle::Postal, QStringLiteral("Huck Finn")), result);
+     }
+ 
+@@ -188,7 +188,7 @@ void AddressTest::formatTest()
+ 
+         const QString result(
+             QStringLiteral("Jim Knopf\nLummerlandstr. 1\n"
+-                           "12345 Lummerstadt\n\nGERMANIA"));
++                           "12345 Lummerstadt\n\nGERMANY"));
+ 
+         QCOMPARE(address.formatted(KContacts::AddressFormatStyle::Postal, QStringLiteral("Jim Knopf")), result);
+     }
+@@ -214,7 +214,7 @@ void AddressTest::formatTest()
+         address.setCountry(QStringLiteral("Schweiz"));
+ 
+         // we want the Italian variant of the Swiss format for it_CH
+-        const QString result(QStringLiteral("Dr. Konqui\nCasella postale 5678\nHaus Randa\n1234 Randa\n\nSVIZZERA"));
++        const QString result(QStringLiteral("Dr. Konqui\nCasella postale 5678\nHaus Randa\n1234 Randa\n\nSWITZERLAND"));
+ 
+         QCOMPARE(address.formatted(KContacts::AddressFormatStyle::Postal, QStringLiteral("Dr. Konqui")), result);
+     }
+@@ -228,14 +228,14 @@ void AddressTest::formatTest()
+         address.setCountry(QStringLiteral("CH"));
+ 
+         // we want the Italian variant of the Swiss format for it_CH
+-        const QString result(QStringLiteral("Dr. Konqui\nCasella postale 5678\nHaus Randa\n1234 Randa\n\nSVIZZERA"));
++        const QString result(QStringLiteral("Dr. Konqui\nCasella postale 5678\nHaus Randa\n1234 Randa\n\nSWITZERLAND"));
+         QCOMPARE(address.formatted(KContacts::AddressFormatStyle::Postal, QStringLiteral("Dr. Konqui")), result);
+     }
+ 
+     {
+         KContacts::Address address;
+         address.setCountry(QStringLiteral("CH"));
+-        QCOMPARE(address.formatted(KContacts::AddressFormatStyle::Postal, QString()), QLatin1String("SVIZZERA"));
++        QCOMPARE(address.formatted(KContacts::AddressFormatStyle::Postal, QString()), QLatin1String("SWITZERLAND"));
+     }
+ 
+     {
+@@ -257,14 +257,14 @@ void AddressTest::formatTest()
+         address.setLocality(QStringLiteral("Minato-ku"));
+         address.setPostalCode(QStringLiteral("106-0047"));
+         address.setStreet(QStringLiteral("4-6-28 Minami-Azabu"));
+-        auto result = QString::fromUtf8("4-6-28 Minami-Azabu, Minato-ku\nTOKYO 106-0047\n\nGIAPPONE");
++        auto result = QString::fromUtf8("4-6-28 Minami-Azabu, Minato-ku\nTOKYO 106-0047\n\nJAPAN");
+         QCOMPARE(address.formatted(KContacts::AddressFormatStyle::Postal), result);
+ 
+         address.setRegion(QStringLiteral("東京"));
+         address.setLocality(QStringLiteral("都港区"));
+         address.setPostalCode(QStringLiteral("106-0047"));
+         address.setStreet(QStringLiteral("南麻布 4-6-28"));
+-        result = QString::fromUtf8("〒106-0047\n東京都港区南麻布 4-6-28\n\nGIAPPONE");
++        result = QString::fromUtf8("〒106-0047\n東京都港区南麻布 4-6-28\n\nJAPAN");
+         QCOMPARE(address.formatted(KContacts::AddressFormatStyle::Postal), result);
+     }
+ }
+
+base-commit: 1d757eba019718cab5d3b33a231d19daf31eb8ba
+-- 
+2.37.2
+
diff --git a/gnu/packages/patches/kde-cli-tools-delay-mime-db.patch b/gnu/packages/patches/kde-cli-tools-delay-mime-db.patch
new file mode 100644
index 0000000000..e29b3b192d
--- /dev/null
+++ b/gnu/packages/patches/kde-cli-tools-delay-mime-db.patch
@@ -0,0 +1,26 @@
+From f8cfb96a1540fc3256af95adf8003b75c305183c Mon Sep 17 00:00:00 2001
+From: Petr Hodina <phodina@protonmail.com>
+Date: Fri, 30 Sep 2022 21:55:55 +0200
+Subject: [PATCH] Add delay to update the mime db in testCreateMimeType test
+ function.
+
+
+diff --git a/keditfiletype/tests/filetypestest.cpp b/keditfiletype/tests/filetypestest.cpp
+index e58e6f2..a41d4ad 100644
+--- a/keditfiletype/tests/filetypestest.cpp
++++ b/keditfiletype/tests/filetypestest.cpp
+@@ -315,6 +315,9 @@ private Q_SLOTS:
+         QVERIFY(data.isDirty());
+         QVERIFY(data.sync());
+         MimeTypeWriter::runUpdateMimeDatabase();
++        // QMimeDatabase doesn't even try to update the cache if less than
++        // 5000 ms have passed (can't use qmime_secondsBetweenChecks)
++        QTest::qSleep(5000);
+         QMimeType mime = db.mimeTypeForName(mimeTypeName);
+         QVERIFY(mime.isValid());
+         QCOMPARE(mime.comment(), fakeComment);
+
+base-commit: b5911cda17521156b22429436e19b508aa442a57
+-- 
+2.37.2
+
diff --git a/gnu/packages/patches/libksysguard-qdiriterator-follow-symlinks.patch b/gnu/packages/patches/libksysguard-qdiriterator-follow-symlinks.patch
new file mode 100644
index 0000000000..ec4a34037d
--- /dev/null
+++ b/gnu/packages/patches/libksysguard-qdiriterator-follow-symlinks.patch
@@ -0,0 +1,24 @@
+From 46164a50de4102d02ae9d1d480acdd4b12303db8 Mon Sep 17 00:00:00 2001
+From: Thomas Tuegel <ttuegel@gmail.com>
+Date: Wed, 14 Oct 2015 07:07:22 -0500
+Subject: [PATCH] qdiriterator follow symlinks
+
+---
+ processui/scripting.cpp | 2 +-
+ 1 file changed, 1 insertion(+), 1 deletion(-)
+
+diff --git a/processui/scripting.cpp b/processui/scripting.cpp
+index efed8ff..841761a 100644
+--- a/processui/scripting.cpp
++++ b/processui/scripting.cpp
+@@ -293,7 +293,7 @@ void Scripting::loadContextMenu()
+     const QStringList dirs =
+         QStandardPaths::locateAll(QStandardPaths::GenericDataLocation, QStringLiteral("ksysguard/scripts/"), QStandardPaths::LocateDirectory);
+     for (const QString &dir : dirs) {
+-        QDirIterator it(dir, QStringList() << QStringLiteral("*.desktop"), QDir::NoFilter, QDirIterator::Subdirectories);
++        QDirIterator it(dir, QStringList() << QStringLiteral("*.desktop"), QDir::NoFilter, QDirIterator::Subdirectories | QDirIterator::FollowSymlinks);
+         while (it.hasNext()) {
+             scripts.append(it.next());
+         }
+-- 
+2.5.2
diff --git a/gnu/packages/patches/linux-libre-infodocs-target.patch b/gnu/packages/patches/linux-libre-infodocs-target.patch
new file mode 100644
index 0000000000..e9e6495c26
--- /dev/null
+++ b/gnu/packages/patches/linux-libre-infodocs-target.patch
@@ -0,0 +1,88 @@
+Upstream status: https://marc.info/?l=linux-doc&m=166861669723994&w=2
+
+From 7edb5b278ee383ff9bed525329b2cdbe22317bf2 Mon Sep 17 00:00:00 2001
+From: Maxim Cournoyer <maxim.cournoyer@gmail.com>
+Date: Mon, 14 Nov 2022 22:51:11 -0500
+Subject: [PATCH] doc: add texinfodocs and infodocs targets
+
+Sphinx supports generating Texinfo sources and Info documentation,
+which can be navigated easily and is convenient to search (via the
+indexed nodes or anchors, for example).
+
+This change also causes the html output to appear under its own output
+sub-directory, which makes it easier to install, since it's clean from
+.doctrees or other output formats.
+
+Signed-off-by: Maxim Cournoyer <maxim.cournoyer@gmail.com>
+---
+ Documentation/Makefile                     | 13 ++++++++++++-
+ Documentation/userspace-api/media/Makefile |  3 ++-
+ Makefile                                   |  2 +-
+ 3 files changed, 15 insertions(+), 3 deletions(-)
+
+diff --git a/Documentation/Makefile b/Documentation/Makefile
+index 64d44c1ecad3..bd8dac560633 100644
+--- a/Documentation/Makefile
++++ b/Documentation/Makefile
+@@ -93,7 +93,16 @@ quiet_cmd_sphinx = SPHINX  $@ --> file://$(abspath $(BUILDDIR)/$3/$4)
+ 
+ htmldocs:
+ 	@$(srctree)/scripts/sphinx-pre-install --version-check
+-	@+$(foreach var,$(SPHINXDIRS),$(call loop_cmd,sphinx,html,$(var),,$(var)))
++	@+$(foreach var,$(SPHINXDIRS),$(call loop_cmd,sphinx,html,$(var),html,$(var)))
++
++texinfodocs:
++	@$(srctree)/scripts/sphinx-pre-install --version-check
++	@+$(foreach var,$(SPHINXDIRS),$(call loop_cmd,sphinx,texinfo,$(var),texinfo,$(var)))
++
++# Note: the 'info' Make target is generated by sphinx itself when
++# running the texinfodocs target define above.
++infodocs: texinfodocs
++	$(MAKE) -C $(BUILDDIR)/texinfo info
+ 
+ linkcheckdocs:
+ 	@$(foreach var,$(SPHINXDIRS),$(call loop_cmd,sphinx,linkcheck,$(var),,$(var)))
+@@ -143,6 +152,8 @@ cleandocs:
+ dochelp:
+ 	@echo  ' Linux kernel internal documentation in different formats from ReST:'
+ 	@echo  '  htmldocs        - HTML'
++	@echo  '  texinfodocs     - Texinfo'
++	@echo  '  infodocs        - Info'
+ 	@echo  '  latexdocs       - LaTeX'
+ 	@echo  '  pdfdocs         - PDF'
+ 	@echo  '  epubdocs        - EPUB'
+diff --git a/Documentation/userspace-api/media/Makefile b/Documentation/userspace-api/media/Makefile
+index 00922aa7efde..3d8aaf5c253b 100644
+--- a/Documentation/userspace-api/media/Makefile
++++ b/Documentation/userspace-api/media/Makefile
+@@ -47,10 +47,11 @@ $(BUILDDIR)/lirc.h.rst: ${UAPI}/lirc.h ${PARSER} $(SRC_DIR)/lirc.h.rst.exception
+ 
+ # Media build rules
+ 
+-.PHONY: all html epub xml latex
++.PHONY: all html texinfo epub xml latex
+ 
+ all: $(IMGDOT) $(BUILDDIR) ${TARGETS}
+ html: all
++texinfo: all
+ epub: all
+ xml: all
+ latex: $(IMGPDF) all
+diff --git a/Makefile b/Makefile
+index 58cd4f5e1c3a..b3266c408b6c 100644
+--- a/Makefile
++++ b/Makefile
+@@ -1785,7 +1785,7 @@ $(help-board-dirs): help-%:
+ # Documentation targets
+ # ---------------------------------------------------------------------------
+ DOC_TARGETS := xmldocs latexdocs pdfdocs htmldocs epubdocs cleandocs \
+-	       linkcheckdocs dochelp refcheckdocs
++	       linkcheckdocs dochelp refcheckdocs texinfodocs infodocs
+ PHONY += $(DOC_TARGETS)
+ $(DOC_TARGETS):
+ 	$(Q)$(MAKE) $(build)=Documentation $@
+
+base-commit: 81e7cfa3a9eb4ba6993a9c71772fdab21bc5d870
+-- 
+2.38.1
+
diff --git a/gnu/packages/patches/nautilus-extension-search-path.patch b/gnu/packages/patches/nautilus-extension-search-path.patch
new file mode 100644
index 0000000000..d5dc35b241
--- /dev/null
+++ b/gnu/packages/patches/nautilus-extension-search-path.patch
@@ -0,0 +1,75 @@
+Allow Nautilus to search for extensions in the directories listed
+in $NAUTILUS_EXTENSION_PATH.
+
+diff --git a/src/nautilus-module.c b/src/nautilus-module.c
+index bf474bd..42e2a4e 100644
+--- a/src/nautilus-module.c
++++ b/src/nautilus-module.c
+@@ -211,6 +211,10 @@ static void
+ load_module_dir (const char *dirname)
+ {
+     GDir *dir;
++    static GHashTable *loaded = NULL;
++
++    if (loaded == NULL)
++      loaded = g_hash_table_new (g_str_hash, g_str_equal);
+ 
+     dir = g_dir_open (dirname, 0, NULL);
+ 
+@@ -221,15 +225,22 @@ load_module_dir (const char *dirname)
+         while ((name = g_dir_read_name (dir)))
+         {
+             if (g_str_has_suffix (name, "." G_MODULE_SUFFIX))
+-            {
+-                char *filename;
+-
+-                filename = g_build_filename (dirname,
+-                                             name,
+-                                             NULL);
+-                nautilus_module_load_file (filename);
+-                g_free (filename);
+-            }
++	      {
++		/* Make sure each module is loaded only twice or this could
++		   lead to a crash.  Double loading can occur if DIRNAME
++		   occurs more than once in $NAUTILUS_EXTENSION_PATH.  */
++		if (!g_hash_table_contains (loaded, name))
++		  {
++		    char *filename;
++
++		    filename = g_build_filename (dirname,
++						 name,
++						 NULL);
++		    nautilus_module_load_file (filename);
++		    g_hash_table_add (loaded, g_strdup (name));
++		    g_free (filename);
++		  }
++	      }
+         }
+ 
+         g_dir_close (dir);
+@@ -257,10 +268,24 @@ nautilus_module_setup (void)
+ 
+     if (!initialized)
+     {
++        const gchar *extension_path;
+         initialized = TRUE;
+ 
+         load_module_dir (NAUTILUS_EXTENSIONDIR);
+ 
++	/* Load additional modules from the user-provided search path.  */
++	extension_path = g_getenv ("NAUTILUS_EXTENSION_PATH");
++	if (extension_path)
++	  {
++	    char **extension_dirs, **d;
++
++	    extension_dirs = g_strsplit (extension_path, ":", -1);
++	    for (d = extension_dirs; d != NULL && *d != NULL; d++)
++	      load_module_dir (*d);
++
++	    g_strfreev (extension_dirs);
++	  }
++
+         eel_debug_call_at_shutdown (free_module_objects);
+     }
+ }
diff --git a/gnu/packages/patches/wacomtablet-add-missing-includes.patch b/gnu/packages/patches/wacomtablet-add-missing-includes.patch
new file mode 100644
index 0000000000..cd93938075
--- /dev/null
+++ b/gnu/packages/patches/wacomtablet-add-missing-includes.patch
@@ -0,0 +1,11 @@
+diff -rup wacomtablet-3.1.0/src/kcmodule/styluspagewidget.cpp wacomtablet-3.1.0.new/src/kcmodule/styluspagewidget.cpp
+--- wacomtablet-3.1.0/src/kcmodule/styluspagewidget.cpp	2018-06-22 15:07:58.000000000 +0200
++++ wacomtablet-3.1.0.new/src/kcmodule/styluspagewidget.cpp	2018-07-10 17:38:09.239242847 +0200
+@@ -25,6 +25,7 @@
+ #include "profilemanagement.h"
+ 
+ // common includes
++#include "logging.h"
+ #include "property.h"
+ #include "deviceprofile.h"
+ #include "dbustabletinterface.h"
diff --git a/gnu/packages/patches/wacomtablet-qt5.15.patch b/gnu/packages/patches/wacomtablet-qt5.15.patch
new file mode 100644
index 0000000000..598ac939e8
--- /dev/null
+++ b/gnu/packages/patches/wacomtablet-qt5.15.patch
@@ -0,0 +1,23 @@
+From 4f73ff02b3efd5e8728b18fcf1067eca166704ee Mon Sep 17 00:00:00 2001
+From: Christophe Giboudeaux <christophe@krop.fr>
+Date: Thu, 4 Jun 2020 16:00:38 +0200
+Subject: [PATCH] Fix build with Qt 5.15
+
+---
+ src/kcmodule/pressurecurvewidget.cpp | 1 +
+ 1 file changed, 1 insertion(+)
+
+diff --git a/src/kcmodule/pressurecurvewidget.cpp b/src/kcmodule/pressurecurvewidget.cpp
+index 0c943b3..f047a6c 100644
+--- a/src/kcmodule/pressurecurvewidget.cpp
++++ b/src/kcmodule/pressurecurvewidget.cpp
+@@ -22,6 +22,7 @@
+ //Qt includes
+ #include <QDebug>
+ #include <QPainter>
++#include <QPainterPath>
+ #include <QMouseEvent>
+ #include <QResizeEvent>
+ #include <QTabletEvent>
+-- 
+GitLab
diff --git a/gnu/packages/perl.scm b/gnu/packages/perl.scm
index b8bfe949e3..f04a91e351 100644
--- a/gnu/packages/perl.scm
+++ b/gnu/packages/perl.scm
@@ -1899,14 +1899,14 @@ as defined by two typical specimens of Perl coders.")
 (define-public perl-conf-libconfig
   (package
     (name "perl-conf-libconfig")
-    (version "0.100")
+    (version "0.101")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "mirror://cpan/authors/id/C/CN/CNANGEL/"
                            "Conf-Libconfig-" version ".tar.gz"))
        (sha256
-        (base32 "0qdypqd7mx96bwdjlv13fn6p96bs4w0yv94yv94xa7z5lqkdj4rg"))))
+        (base32 "11dd3kb0k45gqahnnwz50x3b4b25c5jgykkwgf74rcyr0dsy0n5a"))))
     (build-system perl-build-system)
     (native-inputs
      (list perl-extutils-pkgconfig perl-test-deep perl-test-exception
diff --git a/gnu/packages/protobuf.scm b/gnu/packages/protobuf.scm
index a052a38853..f7184bd49a 100644
--- a/gnu/packages/protobuf.scm
+++ b/gnu/packages/protobuf.scm
@@ -189,7 +189,7 @@ internal RPC protocols and file formats.")
 ;; The 3.5 series are the last versions that do not require C++ 11.
 (define-public protobuf-3.5
   (package
-    (inherit protobuf)
+    (inherit protobuf-3.6)
    (version "3.5.1")
    (source (origin
               (method url-fetch)
diff --git a/gnu/packages/python-compression.scm b/gnu/packages/python-compression.scm
index 1426ad9f09..c483d68b5f 100644
--- a/gnu/packages/python-compression.scm
+++ b/gnu/packages/python-compression.scm
@@ -1,9 +1,9 @@
 ;;; GNU Guix --- Functional package management for GNU
 ;;; Copyright © 2017, 2018 Tobias Geerinckx-Rice <me@tobias.gr>
-;;; Copyright © 2017, 2019, 2021 Ricardo Wurmus <rekado@elephly.net>
+;;; Copyright © 2017, 2019, 2021, 2022 Ricardo Wurmus <rekado@elephly.net>
 ;;; Copyright © 2017 Nikita <nikita@n0.is>
 ;;; Copyright © 2017 Julien Lepiller <julien@lepiller.eu>
-;;; Copyright © 2018, 2019, 2020 Efraim Flashner <efraim@flashner.co.il>
+;;; Copyright © 2018-2020, 2022 Efraim Flashner <efraim@flashner.co.il>
 ;;; Copyright © 2020 Nicolas Goaziou <mail@nicolasgoaziou.fr>
 ;;; Copyright © 2020, 2022 Marius Bakke <marius@gnu.org>
 ;;; Copyright © 2021 Brendan Tildesley <mail@brendan.scot>
@@ -31,6 +31,7 @@
   #:use-module (guix gexp)
   #:use-module (guix build-system gnu)
   #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (gnu packages)
   #:use-module (gnu packages libffi)
   #:use-module (gnu packages compression)
@@ -47,21 +48,20 @@
 (define-public python-multivolumefile
   (package
     (name "python-multivolumefile")
-    (version "0.2.2")
+    (version "0.2.3")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "multivolumefile" version))
        (sha256
         (base32
-         "0j46wab4b09s3favjzp3zs1cn2sn8pr7qyngs5wn31hpqqxbbz76"))))
-    (build-system python-build-system)
+         "1mh9sz50s1p8ik83a455pqd57syprad7xhfmk28yb5mwmw58sr50"))))
+    (build-system pyproject-build-system)
     (native-inputs
-     (list python-pep517
-           python-setuptools
-           python-setuptools-scm
+     (list python-setuptools-scm
            python-coverage
            python-coveralls
+           python-hypothesis
            python-pyannotate
            python-pytest
            python-pytest-cov))
@@ -72,6 +72,36 @@ file-object abstraction, making it possible to use multiple files as if they
 were a single file.")
     (license license:lgpl2.1+)))
 
+(define-public python-pybcj
+  (package
+    (name "python-pybcj")
+    (version "1.0.1")
+    (source (origin
+              (method url-fetch)
+              (uri (pypi-uri "pybcj" version))
+              (sha256
+               (base32
+                "1hvm3c3mb20z25kmbzyyn6pr5inx50z0ignl8b0bggxaik82ws4b"))))
+    (build-system pyproject-build-system)
+    (propagated-inputs (list python-importlib-metadata))
+    (native-inputs
+     (list python-coverage
+           python-hypothesis
+           python-pytest
+           python-pytest-cov
+           python-setuptools-scm))
+    (home-page "https://codeberg.org/miurahr/pybcj")
+    (synopsis "BCJ filter library")
+    (description "In data compression, BCJ, short for Branch-Call-Jump, refers
+to a technique that improves the compression of machine code of executable
+binaries by replacing relative branch addresses with absolute ones. This
+allows a LZMA compressor to identify duplicate targets and archive higher
+compression rate.  BCJ is used in the 7-zip compression utility as the default
+filter for executable binaries.
+
+pybcj provides Python bindings to a BCJ implementation in C.")
+    (license license:lgpl2.1+)))
+
 (define-public python-bcj-cffi
   (package
     (name "python-bcj-cffi")
@@ -95,6 +125,59 @@ were a single file.")
 Jump conversion filter by CFFI for Python.")
     (license license:lgpl2.1+)))
 
+(define-public python-brotlicffi
+  (package
+    (name "python-brotlicffi")
+    (version "1.0.9.2")
+    (source (origin
+              (method url-fetch)
+              (uri (pypi-uri "brotlicffi" version))
+              (sha256
+               (base32
+                "15kxgdiqcg0cm6h5xq3vkbhw7674673hcx3n2yicd3wx29l8l90c"))
+              (snippet
+               #~(begin
+                   (use-modules (guix build utils))
+                   (delete-file-recursively "libbrotli")))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+       #:phases
+       #~(modify-phases %standard-phases
+           (add-after 'unpack 'use-shared-brotli
+             (lambda _
+               (setenv "USE_SHARED_BROTLI" "1"))))))
+    (propagated-inputs (list python-cffi))
+    (inputs (list brotli))
+    (home-page "https://github.com/python-hyper/brotlicffi")
+    (synopsis "Python CFFI bindings to the Brotli library")
+    (description "This package provides Python CFFI bindings to the Brotli
+library.")
+    (license license:expat)))
+
+(define-public python-inflate64
+  (package
+    (name "python-inflate64")
+    (version "0.3.1")
+    (source (origin
+              (method url-fetch)
+              (uri (pypi-uri "inflate64" version))
+              (sha256
+               (base32
+                "0767j35gkwaykl1iq9qn8rc25j1ggv56x3d1vzjpk89bzpzdhbdm"))))
+    (build-system pyproject-build-system)
+    (propagated-inputs (list python-importlib-metadata))
+    (native-inputs
+     (list python-pyannotate
+           python-pytest
+           python-setuptools-scm))
+    (home-page "https://pypi.org/project/inflate64/")
+    (synopsis "deflate64 compression/decompression library")
+    (description "The @code{inflate64} package provides @code{Deflater} and
+@code{Inflater} classes to compress and decompress with the Enhanced Deflate
+compression algorithm.")
+    (license license:lgpl2.1+)))
+
 (define-public python-isal
   (package
     (name "python-isal")
@@ -124,24 +207,50 @@ Jump conversion filter by CFFI for Python.")
 and decompression by implementing Python bindings for the ISA-L library.")
     (license license:expat)))
 
+(define-public python-pyppmd
+  (package
+    (name "python-pyppmd")
+    (version "1.0.0")
+    (source (origin
+              (method url-fetch)
+              (uri (pypi-uri "pyppmd" version))
+              (sha256
+               (base32
+                "03w4x26mar0ha73c3v39psn1i0k6xrzwmaxfsxysic73jz99np07"))))
+    (build-system pyproject-build-system)
+    (native-inputs
+     (list python-coverage
+           python-hypothesis
+           python-pytest
+           python-pytest-benchmark
+           python-pytest-cov
+           python-pytest-timeout
+           python-setuptools-scm))
+    (home-page "https://github.com/miurahr/pyppmd")
+    (synopsis "PPMd compression/decompression library")
+    (description "Pyppmd provides classes and functions for compressing and
+decompressing text data, using the @dfn{Prediction by partial matching} (PPM)
+compression algorithm variation H and I.2.  It provides an API similar to
+Python's zlib/bz2/lzma modules.")
+    (license license:lgpl2.1+)))
+
 (define-public python-ppmd-cffi
   (package
     (name "python-ppmd-cffi")
-    (version "0.3.3")
+    (version "0.5.0")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "ppmd-cffi" version))
        (sha256
         (base32
-         "01wcd9l6pp6hivdmd275qh9dhcwficjqfl67hxix5n07vvq7jzz0"))))
+         "0vprpl29fkflqx0m6anfpx7q7i4cw0d0qxcdm91k4pl82dcad81g"))))
     (build-system python-build-system)
     (propagated-inputs
      (list python-cffi))
     (native-inputs
-     (list python-setuptools
+     (list python-hypothesis
            python-setuptools-scm
-           python-pep517
            python-coverage
            python-pytest
            python-pytest-cov))
@@ -155,23 +264,27 @@ several possible methods.")
 (define-public python-py7zr
   (package
     (name "python-py7zr")
-    (version "0.14.1")
+    (version "0.20.2")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "py7zr" version))
        (sha256
         (base32
-         "1zmgp7yax328fj8yj8pj4l7yh78hp727j6wk12vfi6nmi82wl32i"))))
-    (build-system python-build-system)
+         "0lwniinfr3rb10n0c203a09vz06vxnnj637yqn8ipdlml89gj7kr"))))
+    (build-system pyproject-build-system)
     (propagated-inputs
-     (list python-bcj-cffi
+     (list python-brotli
+           python-brotlicffi
+           python-importlib-metadata
+           python-inflate64
            python-multivolumefile
-           python-ppmd-cffi
-           python-pycryptodome
+           python-psutil
+           python-pybcj
+           python-pycryptodomex
+           python-pyppmd
            python-pyzstd
-           python-texttable
-           python-zstandard))
+           python-texttable))
     (native-inputs
      (list python-setuptools
            python-setuptools-scm
@@ -429,14 +542,16 @@ wrapper.  It provides a backport of the @code{Path} object.")
 (define-public python-zstandard
   (package
     (name "python-zstandard")
-    (version "0.15.2")
+    (version "0.19.0")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "zstandard" version))
        (sha256
-        (base32 "0by9z7nxnkzhmza075q6q91rs8lnpf91129k8ppv7kymbwshipjj"))))
+        (base32 "0qvqhs121spk7yc1l20samflxx47waxv3xm55ksxpn1djk6jzl9i"))))
     (build-system python-build-system)
+    (propagated-inputs
+     (list python-cffi))
     (native-inputs
      (list python-hypothesis))
     (home-page "https://github.com/indygreg/python-zstandard")
@@ -449,17 +564,18 @@ provided.")
 (define-public python-pyzstd
   (package
     (name "python-pyzstd")
-    (version "0.14.3")
+    (version "0.15.3")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "pyzstd" version))
        (sha256
         (base32
-         "1d3mngs45w2p490vrq5ymd2wz4lp15phmks1ilcx4k7amgibml3d"))))
+         "0wkli2i4my79l43b996bdga0fac8s8nfd1zjyzl46lwmsfsxlkmc"))))
     (build-system python-build-system)
     (home-page "https://github.com/animalize/pyzstd")
     (synopsis "Zstandard bindings for Python")
-    (description "This package provides Python bindings to the Zstandard (zstd)
+    (description "This package provides Python bindings to the
+Zstandard (zstd)
 compression library.  The API is similar to Python's bz2/lzma/zlib module.")
     (license license:bsd-3)))
diff --git a/gnu/packages/python-web.scm b/gnu/packages/python-web.scm
index 905d79886f..4f3a587c6a 100644
--- a/gnu/packages/python-web.scm
+++ b/gnu/packages/python-web.scm
@@ -4743,6 +4743,65 @@ Google search engine.  Its module is called @code{googlesearch}.")
     (description "Python client library for Google's discovery based APIs")
     (license license:asl2.0)))
 
+(define-public whoogle-search
+  (package
+    (name "whoogle-search")
+    (version "0.8.0")
+    (source (origin
+              (method url-fetch)
+              (uri (pypi-uri "whoogle-search" version))
+              (sha256
+               (base32
+                "0h8cl9bkd3vx17kbvcnmc8cy6pc29lxr0drxm84kj37ka788cj2g"))))
+    (build-system python-build-system)
+    (arguments
+     (list
+      ;; The tests need network access
+      #:tests? #f))
+    (propagated-inputs
+     (list python-attrs
+           python-beautifulsoup4
+           python-cachelib
+           python-certifi
+           python-cffi
+           python-brotli
+           python-chardet
+           python-click
+           python-cryptography
+           python-cssutils
+           python-defusedxml
+           python-flask
+           python-flask-session
+           python-idna
+           python-itsdangerous
+           python-jinja2
+           python-markupsafe
+           python-more-itertools
+           python-packaging
+           python-pluggy
+           python-py
+           python-pycodestyle
+           python-pycparser
+           python-pyopenssl
+           python-pyparsing
+           python-pysocks
+           python-dateutil
+           python-requests
+           python-soupsieve
+           python-stem
+           python-urllib3
+           python-waitress
+           python-wcwidth
+           python-werkzeug
+           python-dotenv))
+    (home-page "https://github.com/benbusby/whoogle-search")
+    (synopsis "Self-hosted, ad-free, privacy-respecting metasearch engine")
+    (description
+     "Get Google results, but without any ads, javascript, AMP links,
+cookies, or IP address tracking.  Quick and simple to implement as a primary
+search engine replacement on both desktop and mobile.")
+    (license license:expat)))
+
 (define-public python-hawkauthlib
   (package
     (name "python-hawkauthlib")
diff --git a/gnu/packages/python-xyz.scm b/gnu/packages/python-xyz.scm
index 509d57964f..7fefbc5bff 100644
--- a/gnu/packages/python-xyz.scm
+++ b/gnu/packages/python-xyz.scm
@@ -104,7 +104,7 @@
 ;;; Copyright © 2021 Maxime Devos <maximedevos@telenet.be>
 ;;; Copyright © 2021 Hugo Lecomte <hugo.lecomte@inria.fr>
 ;;; Copyright © 2021 Franck Pérignon <franck.perignon@univ-grenoble-alpes.fr>
-;;; Copyright © 2021 Petr Hodina <phodina@protonmail.com>
+;;; Copyright © 2021, 2022 Petr Hodina <phodina@protonmail.com>
 ;;; Copyright © 2021 Simon Streit <simon@netpanic.org>
 ;;; Copyright © 2021 Daniel Meißner <daniel.meissner-i4k@ruhr-uni-bochum.de>
 ;;; Copyright © 2021, 2022 Pradana Aumars <paumars@courrier.dev>
@@ -3075,6 +3075,41 @@ applications. dogtail scripts are written in Python and executed like any
 other Python program.")
     (license license:gpl2+)))
 
+(define-public python-doxyqml
+  (package
+    (name "python-doxyqml")
+    (version "0.5.1")
+    (source (origin
+              (method url-fetch)
+              (uri (pypi-uri "doxyqml" version))
+              (sha256
+               (base32
+                "1f0jjqvamly4hn7f1palvq27z6yr694rfzyxrb6g0ysbbawxkvq9"))))
+    (build-system python-build-system)
+    (home-page "http://agateau.com/projects/doxyqml")
+    (synopsis "Doxygen input filter for QML files")
+    (description
+     "This package provides a Doxygen input filter for QML files.")
+    (license license:bsd-3)))
+
+(define-public python-doxypypy
+  (package
+    (name "python-doxypypy")
+    (version "0.8.8.6")
+    (source (origin
+              (method url-fetch)
+              (uri (pypi-uri "doxypypy" version))
+              (sha256
+               (base32
+                "06z0vbh975g42z5szbfvn9i3bif3xwr5pncqd4fvjzjkbi2p2xb2"))))
+    (build-system python-build-system)
+    (arguments '(#:tests? #f))          ;no test suite
+    (home-page "https://github.com/Feneric/doxypypy")
+    (synopsis "Doxygen filter for Python")
+    (description
+     "This package provides a Doxygen filter for Python.")
+    (license license:gpl2+)))
+
 (define-public python-empy
   (package
     (name "python-empy")
@@ -3105,25 +3140,6 @@ system is highly configurable via command line options and embedded
 commands.")
     (license license:lgpl2.1+)))
 
-(define-public python-enum34
-  (package
-    (name "python-enum34")
-    (version "1.1.6")
-    (source
-     (origin
-      (method url-fetch)
-      (uri (pypi-uri "enum34" version))
-      (sha256
-       (base32
-        "1cgm5ng2gcfrkrm3hc22brl6chdmv67b9zvva9sfs7gn7dwc9n4a"))))
-    (build-system python-build-system)
-    (home-page "https://pypi.org/project/enum34/")
-    (synopsis "Backported Python 3.4 Enum")
-    (description
-     "Enum34 is the new Python stdlib enum module available in Python 3.4
-backported for previous versions of Python from 2.4 to 3.3.")
-    (license license:bsd-3)))
-
 (define-public python-parse-type
   (package
     (name "python-parse-type")
@@ -7031,6 +7047,8 @@ as the original project seems to have been abandoned circa 2007.")
     (build-system python-build-system)
     (arguments
      `(#:tests? #f))                  ; Tests try to access the network.
+    (propagated-inputs
+     (list python-six))
     (home-page "http://pagekite.net/wiki/Floss/PySocksipyChain/")
     (synopsis "Python SOCKS module with chained proxies support")
     (description
@@ -10254,16 +10272,18 @@ more advanced mathematics.")
 (define-public python-bigfloat
   (package
     (name "python-bigfloat")
-    (version "0.3.0")
+    (version "0.4.0")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "bigfloat" version))
        (sha256
-        (base32 "0xd7q4l7v0f463diznjv4k9wlaks80pn9drdqmfifi7zx8qvybi6"))))
+        (base32 "1f0c1hdr39bbl5rds5r1waa1papjmjiyp0ixs64mkjiahzg6pfaq"))))
     (build-system python-build-system)
     (inputs
      (list mpfr))
+    (propagated-inputs
+     (list python-six))
     (home-page "https://github.com/mdickinson/bigfloat")
     (synopsis "Arbitrary precision floating-point arithmetic for Python")
     (description
@@ -16025,6 +16045,20 @@ way.")
               (sha256
                (base32
                 "00yvj8bxmhhhhd74v7j0x673is7vizmxwgb3dd5xmnkr74ybyi7w"))))
+    (arguments
+     (list
+      #:phases
+      '(modify-phases %standard-phases
+         (add-after 'unpack 'disable-test
+           (lambda _
+             ;; See https://github.com/bmc/munkres/issues/40
+             (substitute* "test/test_munkres.py"
+               (("^def test_profit_float" m)
+                (string-append "\
+import platform
+@pytest.mark.skipif(platform.architecture()[0] == \"32bit\",
+  reason=\"Fails on 32 bit architectures\")
+" m))))))))
     (build-system python-build-system)
     (native-inputs (list python-pytest-6))
     (home-page "https://software.clapper.org/munkres/")
@@ -17613,8 +17647,10 @@ It supports TSIG authenticated messages and EDNS0.")
            (lambda _
              (substitute* "setup.py"
                (("import DNS") "")
-               (("DNS.__version__") (string-append "\"" ,version "\"")))
-             #t)))
+               (("DNS.__version__") (string-append "\"" ,version "\"")))))
+         ;; For the same reason, drop the sanity check because the library
+         ;; fails to load without /etc/resolv.conf.
+         (delete 'sanity-check))
        #:tests? #f)) ; Also skip the tests.
     (home-page "https://launchpad.net/py3dns")
     (synopsis "Python 3 DNS library")
@@ -27371,14 +27407,14 @@ and pandoc-citeproc.")
 (define-public python-rnc2rng
   (package
     (name "python-rnc2rng")
-    (version "2.6.4")
+    (version "2.6.6")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "rnc2rng" version))
        (sha256
         (base32
-         "1kmp3iwxxyzjsd47j2sprd47ihhkwhb3yydih3af5bbfq0ibh1w8"))))
+         "1wbqvz2bhq2f5kqi7q2q3m9y5vs9rj970zhnjh502pvvhmbx20as"))))
     (build-system python-build-system)
     (propagated-inputs
      (list python-rply))
@@ -27575,6 +27611,8 @@ module patches @code{asyncio} to allow nested use of @code{asyncio.run} and
          "1mzk4yabxj6r149fswhis18hd8dnag5sj8i4wb06450zq3pi8dh7"))))
     (native-inputs
      (list unzip))
+    (propagated-inputs
+     (list python-six))
     (build-system python-build-system)
     (arguments '(#:tests? #f))  ; No test suite.
     (home-page "https://www.parallelpython.com")
@@ -29603,7 +29641,7 @@ development, testing, production]};
                     (lambda* (#:key tests? #:allow-other-keys)
                       (when tests?
                         (invoke "pytest" "-vv")))))))
-    (native-inputs (list python-pytest python-pytest-mock))
+    (native-inputs (list python-pytest python-pytest-mock python-numpy))
     (propagated-inputs (list python-jedi python-pygments python-urwid
                              python-urwid-readline))
     (home-page "https://documen.tician.de/pudb/")
diff --git a/gnu/packages/qt.scm b/gnu/packages/qt.scm
index 8cbb2c6a07..7694334a2c 100644
--- a/gnu/packages/qt.scm
+++ b/gnu/packages/qt.scm
@@ -25,6 +25,7 @@
 ;;; Copyright © 2021 Nicolò Balzarotti <nicolo@nixo.xyz>
 ;;; Copyright © 2022 Foo Chuan Wei <chuanwei.foo@hotmail.com>
 ;;; Copyright © 2022 Zhu Zihao <all_but_last@163.com>
+;;; Copyright © 2022 Petr Hodina <phodina@protonmail.com>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -48,6 +49,7 @@
   #:use-module (guix git-download)
   #:use-module (guix build-system cmake)
   #:use-module (guix build-system gnu)
+  #:use-module (guix build-system meson)
   #:use-module (guix build-system trivial)
   #:use-module (guix build-system python)
   #:use-module (guix build-system qt)
@@ -59,17 +61,21 @@
   #:use-module (gnu packages bash)
   #:use-module (gnu packages base)
   #:use-module (gnu packages bison)
+  #:use-module (gnu packages check)
   #:use-module (gnu packages cmake)
   #:use-module (gnu packages compression)
+  #:use-module (gnu packages cpp)
   #:use-module (gnu packages cups)
   #:use-module (gnu packages curl)
   #:use-module (gnu packages databases)
   #:use-module (gnu packages documentation)
+  #:use-module (gnu packages elf)
   #:use-module (gnu packages enchant)
   #:use-module (gnu packages fontutils)
   #:use-module (gnu packages flex)
   #:use-module (gnu packages freedesktop)
   #:use-module (gnu packages gcc)
+  #:use-module (gnu packages gdb)
   #:use-module (gnu packages ghostscript)
   #:use-module (gnu packages gl)
   #:use-module (gnu packages glib)
@@ -140,8 +146,7 @@
          (modify-phases %standard-phases
            (add-after 'unpack 'chdir
              (lambda _
-               (chdir "libqite")
-               #t)))))
+               (chdir "libqite"))))))
       (inputs
        (list qtbase-5 qtmultimedia-5))
       (home-page "https://github.com/Ri0n/qite/")
@@ -219,10 +224,10 @@ window managers, that don't provide Qt integration by themselves.")
       (native-inputs
        (list cmake-shared extra-cmake-modules pkg-config))
       (inputs
-       `(("qtbase" ,qtbase-5)
-         ("qtwayland" ,qtwayland-5)
-         ("wayland" ,wayland)
-         ("xkbcommon" ,libxkbcommon)))
+       (list qtbase-5
+             qtwayland-5
+             wayland
+             libxkbcommon))
       (synopsis "Material Decoration for Qt")
       (description "MaterialDecoration is a client-side decoration for Qt
 applications on Wayland.")
@@ -254,8 +259,7 @@ applications on Wayland.")
          (add-before 'check 'check-setup
            (lambda _
              ;; make Qt render "offscreen", required for tests
-             (setenv "QT_QPA_PLATFORM" "offscreen")
-             #t)))))
+             (setenv "QT_QPA_PLATFORM" "offscreen"))))))
     (home-page "https://github.com/steveire/grantlee")
     (synopsis "Libraries for text templating with Qt")
     (description "Grantlee Templates can be used for theming and generation of
@@ -820,6 +824,69 @@ developers using C++ or QML, a CSS & JavaScript like language.")
             (variable "XDG_CONFIG_DIRS")
             (files '("etc/xdg")))))))
 
+(define-public qt3d-5
+  (package
+    (inherit qtbase-5)
+    (name "qt3d")
+    (version "5.15.5")
+    (source (origin
+              (method url-fetch)
+              (uri (qt-urls name version))
+              (sha256
+               (base32
+                "1m3y7d58crn0qgfwkimxcggssn2pbs8nj5b9diwns6rwqg4aqk20"))))
+    (propagated-inputs `())
+    (native-inputs (list perl))
+    (inputs (list mesa qtbase-5 vulkan-headers zlib))
+    (arguments
+     (list #:phases #~(modify-phases %standard-phases
+                        (add-before 'configure 'configure-qmake
+                          (lambda* (#:key inputs outputs #:allow-other-keys)
+                            (let* ((tmpdir (string-append (getenv "TMPDIR")))
+                                   (qmake (string-append tmpdir "/qmake"))
+                                   (qt.conf (string-append tmpdir "/qt.conf")))
+                              (symlink (which "qmake") qmake)
+                              (setenv "PATH"
+                                      (string-append tmpdir ":"
+                                                     (getenv "PATH")))
+                              (with-output-to-file qt.conf
+                                (lambda ()
+                                  (format #t "[Paths]
+Prefix=~a
+ArchData=lib/qt5
+Data=share/qt5
+Documentation=share/doc/qt5
+Headers=include/qt5
+Libraries=lib
+LibraryExecutables=lib/qt5/libexec
+Binaries=bin
+Tests=tests
+Plugins=lib/qt5/plugins
+Imports=lib/qt5/imports
+Qml2Imports=lib/qt5/qml
+Translations=share/qt5/translations
+Settings=etc/xdg
+Examples=share/doc/qt5/examples
+HostPrefix=~a
+HostData=lib/qt5
+HostBinaries=bin
+HostLibraries=lib
+
+[EffectiveSourcePaths]
+HostPrefix=~a
+HostData=lib/qt5"
+                                          #$output #$output #$(this-package-input
+                                                               "qtbase")))))))
+                        (replace 'configure
+                          (lambda* (#:key inputs outputs #:allow-other-keys)
+                            (invoke "qmake"
+                                    "QT_BUILD_PARTS = libs tools tests")))
+                        (add-before 'check 'set-display
+                          (lambda _
+                            (setenv "QT_QPA_PLATFORM" "offscreen"))))))
+    (synopsis "Qt module for 3D")
+    (description "The Qt3d module provides classes for displaying 3D.")))
+
 (define-public qt5compat
   (package
     (name "qt5compat")
@@ -1802,9 +1869,22 @@ that helps in Qt development.")))
      (list
       ;; The build system attempts to fetch online resources and fails when
       ;; building the test suite.
-      #:configure-flags #~(list "-DQT_BUILD_TESTS=OFF")))
+      #:configure-flags #~(list "-DQT_BUILD_TESTS=OFF")
+      #:phases #~(modify-phases %standard-phases
+                   (add-after 'install 'sanity-check
+                     (lambda* (#:key outputs #:allow-other-keys)
+                       ;; This validation exists to validate that the dynamic
+                       ;; library for Clang works as intended; there was
+                       ;; originally problems due to left-overs patching the
+                       ;; value of BUILD_SHARED_LIBS in CLANG-FROM-LLVM that
+                       ;; would cause the following error: "CommandLine Error:
+                       ;; Option 'filter' registered more than once!"
+                       (invoke/quiet (search-input-file outputs "bin/qdoc")
+                                     "--help"))))))
     (native-inputs (list perl qtdeclarative vulkan-headers))
-    (inputs (list libxkbcommon mesa qtbase))
+    ;; Use clang-15, which is built using as a single shared library, which is
+    ;; what the build system of qttools expects.
+    (inputs (list clang-15 libxkbcommon mesa qtbase))
     (home-page (package-home-page qtbase))
     (synopsis "Qt Tools and Designer modules")
     (description "The Qt Tools module provides a set of applications to browse
@@ -1814,6 +1894,27 @@ that helps in Qt development.")
     ;; LICENSES/Qt-GPL-exception-1.0.txt).
     (license (list license:gpl3))))
 
+(define-public qttranslations
+  (package
+    (name "qttranslations")
+    (version "6.3.1")
+    (source (origin
+              (method url-fetch)
+              (uri (qt-urls name version))
+              (sha256
+               (base32
+                "15yvvxw1vngnjlly6cady05ljamg01qiaqn2vh0xkph855gdbgfp"))))
+    (build-system cmake-build-system)
+    (arguments (list #:tests? #f))
+    (native-inputs (list qtbase qttools))
+    (home-page (package-home-page qtbase))
+    (synopsis "Qt translation catalogs")
+    (description "This package contains the translations for Qt contributed by
+the Qt community.")
+    ;; GPL 3 only with Qt GPL exception 1.0 (see:
+    ;; LICENSES/Qt-GPL-exception-1.0.txt).
+    (license (list license:gpl3))))
+
 (define-public qtscript
   (package (inherit qtsvg-5)
     (name "qtscript")
@@ -1917,12 +2018,12 @@ coloring, and many more.")))
     (native-inputs
      (list perl pkg-config))
     (inputs
-     `(("fontconfig" ,fontconfig)
-       ("freetype" ,freetype)
-       ("libxrender" ,libxrender)
-       ("sdl2" ,sdl2)
-       ("qtbase" ,qtbase-5)
-       ("qtdeclarative-5" ,qtdeclarative-5)))
+     (list fontconfig
+           freetype
+           libxrender
+           sdl2
+           qtbase-5
+           qtdeclarative-5))
     (synopsis "Qt Gamepad module")
     (description "The Qt Gamepad module is an add-on library that enables Qt
 applications to support the use of gamepad hardware and in some cases remote
@@ -2941,8 +3042,7 @@ system libraries.")
                      (string-append source "/" file)
                      (string-append out "/include")))
                   '("SingleApplication"
-                    "singleapplication.h" "singleapplication_p.h"))
-                 #t))))))
+                    "singleapplication.h" "singleapplication_p.h"))))))))
       (inputs
        (list qtbase-5))
       (home-page "https://github.com/itay-grudev/SingleApplication")
@@ -3088,9 +3188,7 @@ module provides support functions to the automatically generated code.")
              (let* ((qtbase (assoc-ref inputs "qtbase"))
                     (qtprinter.h (string-append "\"" qtbase "/include/qt5/QtPrintSupport/qprinter.h\"")))
                (substitute* "sip/QtPrintSupport/qprinter.sip"
-                 (("<qprinter.h>")
-                  qtprinter.h))
-               #t)))
+                 (("<qprinter.h>") qtprinter.h)))))
          (replace 'configure
            (lambda* (#:key inputs outputs #:allow-other-keys)
              (let* ((out (assoc-ref outputs "out"))
@@ -3215,8 +3313,7 @@ contain over 620 classes.")
                  (lambda _ (display "
 from pkgutil import extend_path
 __path__ = extend_path(__path__, __name__)
-")))
-               #t))))))
+")))))))))
     (home-page "https://www.riverbankcomputing.com/software/pyqtwebengine/intro")
     (synopsis "Python bindings for QtWebEngine")
     (description
@@ -3376,8 +3473,7 @@ indicators, code completion and call tips.")
                   (string-append out "/lib")))
                ;; And fix the installed.txt file
                (substitute* "installed.txt"
-                 (("/gnu/store/[^/]+") out)))
-             #t)))))
+                 (("/gnu/store/[^/]+") out))))))))
     (inputs
      `(("qscintilla" ,qscintilla)
        ("python" ,python)
@@ -3405,8 +3501,7 @@ This package provides the Python bindings.")))
                    (match %build-inputs
                      (((names . directories) ...)
                       (union-build (assoc-ref %outputs "out")
-                                   directories)
-                      #t)))))
+                                   directories))))))
     (inputs
      `(("python-pyqt" ,python-pyqt)
        ("python-qscintilla" ,python-qscintilla)))
@@ -3484,8 +3579,7 @@ securely.  It will not store any data unencrypted unless explicitly requested.")
                    (("#include \"qtlockedfile.*\\.cpp\"") "")
                    ;; Unwrap namespace added in the vendoring process.
                    (("QtLP_Private::QtLockedFile")
-                    "QtLockedFile")))
-             #t))))
+                    "QtLockedFile")))))))
       (build-system gnu-build-system)
       (arguments
        `(#:tests? #f                    ; No target
@@ -3509,8 +3603,7 @@ securely.  It will not store any data unencrypted unless explicitly requested.")
                  (("SUBDIRS\\+=examples") ""))
                ;; Fix deprecated functions.
                (substitute* "qtsoap/src/qtsoap.cpp"
-                 (("toAscii") "toUtf8"))
-               #t))
+                 (("toAscii") "toUtf8"))))
            (replace 'configure
              (lambda _
                (for-each (lambda (solution)
@@ -3518,16 +3611,14 @@ securely.  It will not store any data unencrypted unless explicitly requested.")
                              (invoke "./configure" "-library")
                              (invoke "qmake")))
                          '("qtlockedfile" "qtpropertybrowser" "qtservice"
-                           "qtsingleapplication" "qtsoap"))
-               #t))
+                           "qtsingleapplication" "qtsoap"))))
            (replace 'build
              (lambda _
                (for-each (lambda (solution)
                            (with-directory-excursion solution
                              (invoke "make")))
                          '("qtlockedfile" "qtpropertybrowser" "qtservice"
-                           "qtsingleapplication" "qtsoap"))
-               #t))
+                           "qtsingleapplication" "qtsoap"))))
            (replace 'install
              (lambda args
                (for-each (lambda (solution)
@@ -3607,8 +3698,7 @@ that can be only started once per user.
              ;; Remove some incomplete manual pages.
              (for-each delete-file (find-files "doc/man/man3" "^_tmp.*"))
              (mkdir-p man)
-             (copy-recursively "doc/man" man)
-             #t))))))
+             (copy-recursively "doc/man" man)))))))
   (home-page "http://qwt.sourceforge.net")
   (synopsis "Qt widgets for plots, scales, dials and other technical software
 GUI components")
@@ -3850,7 +3940,7 @@ color-related widgets.")
       #:phases
       #~(modify-phases %standard-phases
           (add-after 'unpack 'use-shiboken-dir-only
-            (lambda _ (chdir "sources/shiboken2") #t))
+            (lambda _ (chdir "sources/shiboken2")))
           (add-before 'configure 'make-files-writable-and-update-timestamps
             (lambda _
               ;; The build scripts need to modify some files in
@@ -3861,13 +3951,11 @@ color-related widgets.")
                 (for-each (lambda (file)
                             (make-file-writable file)
                             (utime file circa-1980 circa-1980))
-                          (find-files ".")))
-              #t))
+                          (find-files ".")))))
           (add-before 'configure 'set-build-env
             (lambda _
               (let ((llvm #$(this-package-input "clang-toolchain")))
-                (setenv "CLANG_INSTALL_DIR" llvm)
-                #t))))))
+                (setenv "CLANG_INSTALL_DIR" llvm)))))))
     (home-page "https://wiki.qt.io/Qt_for_Python")
     (synopsis
      "Shiboken generates bindings for C++ libraries using CPython source code")
@@ -3905,7 +3993,7 @@ color-related widgets.")
        ((#:phases p)
         #~(modify-phases #$p
             (replace 'use-shiboken-dir-only
-              (lambda _ (chdir "sources/shiboken6") #t))))
+              (lambda _ (chdir "sources/shiboken6")))))
        ((#:configure-flags flags)
         #~(cons*
            ;; The RUNPATH of shibokenmodule contains the entry in build
@@ -3959,7 +4047,7 @@ color-related widgets.")
       #:phases
       #~(modify-phases %standard-phases
           (add-after 'unpack 'go-to-source-dir
-            (lambda _ (chdir "sources/pyside2") #t))
+            (lambda _ (chdir "sources/pyside2")))
           (add-after 'go-to-source-dir 'fix-qt-module-detection
             (lambda _
               ;; Activate qt module support even if it not in the same
@@ -4054,7 +4142,7 @@ generate Python bindings for your C or C++ code.")
       #:phases
       #~(modify-phases %standard-phases
           (add-after 'unpack 'go-to-source-dir
-            (lambda _ (chdir "sources/pyside6") #t))
+            (lambda _ (chdir "sources/pyside6")))
           (add-after 'go-to-source-dir 'fix-qt-module-detection
             (lambda _
               (substitute* "cmake/PySideHelpers.cmake"
@@ -4114,7 +4202,7 @@ generate Python bindings for your C or C++ code.")))
       #:phases
       #~(modify-phases %standard-phases
           (add-after 'unpack 'go-to-source-dir
-            (lambda _ (chdir "sources/pyside2-tools") #t)))))
+            (lambda _ (chdir "sources/pyside2-tools"))))))
     (home-page "https://wiki.qt.io/Qt_for_Python")
     (synopsis
      "Command line tools for PySide2")
@@ -4291,8 +4379,7 @@ and import their menus over DBus.")
            (lambda* (#:key tests? #:allow-other-keys)
              (when tests?
                (invoke "ctest" "-E" ;; These tests try connect to the internet.
-                       "(kdsoap-webcalls|kdsoap-webcalls_wsdl|kdsoap-test_calc)"))
-             #t)))))
+                       "(kdsoap-webcalls|kdsoap-webcalls_wsdl|kdsoap-test_calc)")))))))
     (home-page "https://www.kdab.com/development-resources/qt-tools/kd-soap/")
     (synopsis "Qt SOAP component")
     (description "KD SOAP is a tool for creating client applications for web
@@ -4300,6 +4387,349 @@ services using the XML based SOAP protocol and without the need for a dedicated
 web server.")
     (license (list license:gpl2 license:gpl3))))
 
+(define-public libaccounts-qt
+  (package
+    (name "libaccounts-qt")
+    (version "1.16")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://gitlab.com/accounts-sso/libaccounts-qt")
+                    (commit (string-append "VERSION_" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "1vmpjvysm0ld8dqnx8msa15hlhrkny02cqycsh4k2azrnijg0xjz"))))
+    (build-system gnu-build-system)
+    (arguments
+     (list #:tests? #f                  ;TODO
+           #:phases
+           #~(modify-phases %standard-phases
+               (replace 'configure
+                 (lambda _
+                   (substitute* "tests/tst_libaccounts.pro"
+                     (("QMAKE_RPATHDIR = \\$\\$\\{QMAKE_LIBDIR\\}")
+                      (string-append "QMAKE_RPATHDIR ="
+                                     #$output "/lib")))
+                   (invoke "qmake"
+                           (string-append "PREFIX=" #$output)
+                           (string-append "LIBDIR=" #$output "/lib")))))))
+    ;; * SignOnQt5 (required version >= 8.55), D-Bus service which performs
+    ;; user authentication on behalf of its clients,
+    ;; <https://gitlab.com/accounts-sso/signond>
+    (native-inputs (list doxygen pkg-config qtbase-5 qttools-5))
+    (inputs (list glib signond libaccounts-glib))
+    (home-page "https://accounts-sso.gitlab.io/")
+    (synopsis "Qt5 bindings for libaccounts-glib")
+    (description
+     "Accounts SSO is a framework for application developers who
+wish to acquire, use and store web account details and credentials.  It
+handles the authentication process of an account and securely stores the
+credentials and service-specific settings.")
+    (license license:lgpl2.1+)))
+
+(define-public libsignon-glib
+  (package
+    (name "libsignon-glib")
+    (version "2.1")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://gitlab.com/accounts-sso/libsignon-glib")
+                    (commit (string-append "VERSION_" version))
+                    (recursive? #t)))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "0gnx9gqsh0hcfm1lk7w60g64mkn1iicga5f5xcy1j9a9byacsfd0"))))
+    (build-system meson-build-system)
+    (arguments
+     (list #:tests? #f                  ;TODO: ninja: no work to do.
+           #:imported-modules `((guix build python-build-system)
+                                ,@%meson-build-system-modules)
+           #:modules '(((guix build python-build-system)
+                        #:select (python-version))
+                       (guix build meson-build-system)
+                       (guix build utils))
+           #:configure-flags
+           #~(list "-Dtests=true"
+                   (string-append "-Dpy-overrides-dir="
+                                  #$output "/lib/python"
+                                  (python-version #$(this-package-input
+                                                     "python"))
+                                  "/site-packages/gi/overrides"))))
+    (native-inputs (list dbus
+                         dbus-test-runner
+                         `(,glib "bin")
+                         gobject-introspection
+                         gtk-doc
+                         pkg-config
+                         vala))
+    (inputs (list check signond python python-pygobject))
+    (propagated-inputs (list glib))
+    (home-page "https://accounts-sso.gitlab.io/libsignon-glib/")
+    (synopsis "Single signon authentication library for GLib applications")
+    (description
+     "This package provides single signon authentication library for
+GLib applications.")
+    (license license:lgpl2.1+)))
+
+(define-public packagekit-qt5
+  (package
+    (name "packagekit-qt5")
+    (version "1.0.2")
+    (source (origin
+              (method git-fetch)
+			  (uri (git-reference
+			  (url "https://github.com/hughsie/PackageKit-Qt")
+			  (commit (string-append "v" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "1d20r503msw1vix3nb6a8bmdqld7fj8k9jk33bkqsc610a2zsms6"))))
+    (build-system cmake-build-system)
+    (arguments '(#:tests? #f))          ;no test suite
+    (native-inputs (list pkg-config))
+    (inputs (list packagekit qtbase-5))
+    (home-page "https://www.freedesktop.org/software/PackageKit/pk-intro.html")
+    (synopsis "Qt5 bindings for PackageKit")
+    (description "Provides Qt5 bindings to PackageKit which is a DBUS
+abstraction layer that allows the session user to manage packages in
+a secure way.")
+    (license license:lgpl2.1+)))
+
+(define-public signond
+  (package
+    (name "signond")
+    (version "8.61")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://gitlab.com/accounts-sso/signond")
+                    (commit (string-append "VERSION_" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "0k6saz5spys4a4p6ws0ayrjks2gqdqvz7zfmlhdpz5axha0gbqq4"))))
+    (build-system qt-build-system)
+    (native-inputs (list doxygen pkg-config qtbase-5 qttools-5))
+    (inputs (list dbus glib libaccounts-glib))
+    (arguments
+     (list #:tests? #f                  ; Figure out how to run tests
+           #:phases
+           #~(modify-phases %standard-phases
+               (delete 'validate-runpath)
+               (replace 'configure
+                 (lambda _
+                   (substitute* "src/signond/signond.pro"
+                     (("/etc/")
+                      (string-append #$output "/etc/")))
+                   (substitute*
+                       '("tests/extensions/extensions.pri"
+                         "tests/signond-tests/mock-ac-plugin/plugin.pro"
+                         "tests/signond-tests/identity-tool.pro"
+                         "tests/signond-tests/mock-ac-plugin/identity-ac-helper.pro"
+                         "tests/libsignon-qt-tests/libsignon-qt-tests.pro"
+                         "tests/signond-tests/signond-tests.pri")
+                     (("QMAKE_RPATHDIR = \\$\\$\\{QMAKE_LIBDIR\\}")
+                      (string-append "QMAKE_RPATHDIR = "
+                                     #$output "/lib:"
+                                     #$output "/lib/signon")))
+                   (invoke "qmake"
+                           (string-append "PREFIX=" #$output)
+                           (string-append "LIBDIR=" #$output "/lib")))))))
+    (home-page "http://accounts-sso.gitlab.io/signond/index.html")
+    (synopsis "Perform user authentication over D-Bus")
+    (description "This package provides a D-Bus service which performs user
+authentication on behalf of its clients.")
+    (license license:lgpl2.1+)))
+
+(define-public signon-plugin-oauth2
+  (package
+    (name "signon-plugin-oauth2")
+    (version "0.25")
+    (home-page "https://gitlab.com/accounts-sso/signon-plugin-oauth2")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url home-page)
+                    (commit (string-append "VERSION_" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "16aslnyk8jdg03zcg97rp6qzd0gmclj14hyhliksz8jgfz1l0w7c"))))
+    (build-system qt-build-system)
+    (native-inputs (list doxygen pkg-config))
+    (inputs (list signond))
+    (arguments
+     (list #:tests? #f                  ;no tests
+           #:make-flags #~(list (string-append "INSTALL_ROOT=" #$output))
+           #:phases
+           #~(modify-phases %standard-phases
+               (replace 'configure
+                 (lambda _
+                   (substitute* "common-project-config.pri"
+                     (("-Werror")
+                      ""))
+                   (invoke "qmake"
+                           (string-append "PREFIX=" #$output)
+                           (string-append "LIBDIR=" #$output "/lib")))))))
+    (synopsis "OAuth 2 plugin for signon")
+    (description
+     "This plugin for the Accounts-SSO SignOn daemon handles the OAuth
+1.0 and 2.0 authentication protocols.")
+    (license license:lgpl2.1+)))
+
+(define-public clazy
+  (package
+    (name "clazy")
+    (version "1.11")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/KDE/clazy")
+                    (commit (string-append "v" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "1y0n1jknq566z1rifkgdm1yqb0mw564lp51jidfz7q9w91spijci"))))
+    (build-system cmake-build-system)
+    (native-inputs (list python))
+    (inputs (list clang llvm))
+    (home-page "https://github.com/KDE/clazy/")
+    (synopsis "Qt-oriented static code analyzer")
+    (description "clazy is a compiler plugin which allows @command{clang} to
+understand Qt semantics.  It can emit more than fifty (50) Qt-related compiler
+warnings, ranging from unneeded memory allocations to misuses of the API,
+including @i{fix-its} for automatic refactoring.")
+    (license license:lgpl2.0+)))
+
+(define-public qt-creator
+  (package
+    (name "qt-creator")
+    (version "9.0.0")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append
+                    "https://download.qt.io/official_releases/qtcreator/"
+                    (version-major+minor version) "/" version
+                    "/qt-creator-opensource-src-" version ".tar.gz"))
+              (modules '((guix build utils)))
+              (snippet '(begin
+                          (for-each
+                           delete-file-recursively
+                           ;; Remove bundled libraries, where supported.
+                           ;; TODO: package and unbundle litehtml
+                           '("src/libs/3rdparty/yaml-cpp"
+                             "src/shared/qbs/src/shared/qtscript/src/3rdparty"
+                             "tests/unit/unittest/3rdparty"
+                             ;; Marketplace recommends nonfree extensions;
+                             ;; remove it.
+                             "src/plugins/marketplace"))
+                          (substitute* "src/plugins/CMakeLists.txt"
+                            (("add_subdirectory\\(marketplace).*") ""))
+                          (substitute* "src/plugins/plugins.qbs"
+                            ((".*marketplace/marketplace.qbs.*") ""))))
+              (sha256
+               (base32
+                "1adyxs0cnqx14gwzkvh909c52449ia6y87n1r4qf6wwydhch43cs"))))
+    (build-system qt-build-system)
+    (arguments
+     (list
+      #:qtbase qtbase
+      #:configure-flags
+      #~(list "-DWITH_DOCS=ON"
+              "-DBUILD_DEVELOPER_DOCS=ON"
+              "-DCMAKE_VERBOSE_MAKEFILE=ON"
+              "-DWITH_TESTS=ON"
+              ;; Extend the RUNPATH with lib/qtcreator, which contains
+              ;; multiple shared objects.
+              (string-append "-DCMAKE_SHARED_LINKER_FLAGS=-Wl,-rpath="
+                             #$output "/lib/qtcreator"))
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'fix-tests-build
+            (lambda _
+              ;; Add a missing link directive (see:
+              ;; https://bugreports.qt.io/browse/QTCREATORBUG-28434).
+              (substitute* "src/libs/tracing/CMakeLists.txt"
+                (("DEPENDS Utils Qt5::Qml Qt5::Quick")
+                 "DEPENDS Utils Qt5::Quick")
+                (("PUBLIC_DEPENDS Qt5::Widgets")
+                 "PUBLIC_DEPENDS Qt5::Widgets Qt5::Qml"))))
+          (add-after 'unpack 'patch-paths
+            (lambda* (#:key inputs #:allow-other-keys)
+              (substitute* '("src/libs/utils/commandline.cpp"
+                             "src/libs/utils/deviceshell.cpp")
+                (("/bin/sh")
+                 (search-input-file inputs "bin/sh")))
+              (substitute* "src/libs/utils/qtcprocess.cpp"
+                (("/usr/bin/env")
+                 (search-input-file inputs "bin/env")))
+              (substitute* "tests/auto/utils/qtcprocess/tst_qtcprocess.cpp"
+                (("/bin/sh")
+                 (which "sh")))))
+          (add-before 'build 'build-doc
+            (lambda _
+              (invoke "cmake" "--build" "." "--target=docs" "-v")))
+          (add-after 'build-doc 'install-doc
+            (lambda _
+              (invoke "cmake" "--install" "." "--prefix" #$output
+                      "--component=qch_docs")
+              (invoke "cmake" "--install" "." "--prefix" #$output
+                      "--component=html_docs")))
+          (replace 'check
+            ;; Loosely based on .github/workflows/build_cmake.yml.
+            (lambda* (#:key tests? parallel-tests? #:allow-other-keys)
+              (when tests?
+                (invoke "xvfb-run"      ;for the 'renderpass' tests
+                        "ctest" "-j" (if parallel-tests?
+                                         (number->string (parallel-job-count))
+                                         "1")
+                        "--label-exclude" "exclude_from_precheck"
+                        "--exclude-regex" "tst_perfdata"))))
+          (add-after 'qt-wrap 'wrap-bin
+            ;; Make a few well-integrated tools readily available.
+            (lambda* (#:key inputs outputs #:allow-other-keys)
+              (wrap-program (search-input-file outputs "bin/qtcreator")
+                `("PATH" suffix ,(map (lambda (c)
+                                        (dirname (search-input-file inputs c)))
+                                      '("bin/clang-tidy"
+                                        "bin/clazy-standalone"
+                                        "bin/gdb"
+                                        "bin/valgrind")))))))))
+    (native-inputs
+     (list googletest
+           pkg-config
+           python
+           qttools
+           qttranslations
+           vulkan-headers
+           xvfb-run))
+    (inputs
+     (list bash-minimal
+           coreutils-minimal
+           clang
+           clazy
+           elfutils
+           gdb
+           libxkbcommon
+           llvm
+           qt5compat
+           qtdeclarative
+           qtshadertools
+           qtsvg
+           yaml-cpp
+           valgrind
+           vulkan-loader
+           `(,zstd "lib")))
+    (home-page "https://www.qt.io/")
+    (synopsis "Integrated development environment (IDE) for Qt")
+    (description "Qt Creator is an IDE tailored to the needs of Qt developers.
+It includes features such as an advanced code editor, a visual debugger and a
+@acronym{GUI, Graphical User Interface} designer.")
+    (license license:gpl3+)))           ;with the Qt Company GPL Exception 1.0
+
 ;;;
 ;;; Avoid adding new packages to the end of this file. To reduce the chances
 ;;; of a merge conflict, place them above by existing packages with similar
diff --git a/gnu/packages/radio.scm b/gnu/packages/radio.scm
index e36dc55795..3834599cfc 100644
--- a/gnu/packages/radio.scm
+++ b/gnu/packages/radio.scm
@@ -175,7 +175,7 @@ used as a drop-in substitute for @code{libfec}.")
 (define-public liquid-dsp
   (package
     (name "liquid-dsp")
-    (version "1.4.0")
+    (version "1.5.0")
     (source
      (origin (method git-fetch)
              (uri (git-reference
@@ -183,21 +183,25 @@ used as a drop-in substitute for @code{libfec}.")
                    (commit (string-append "v" version))))
              (file-name (git-file-name name version))
              (sha256
-              (base32 "0mr86z37yycrqwbrmsiayi1vqrgpjq0pn1c3p1qrngipkw45jnn0"))))
+              (base32 "0m0bhj80rs9yhfwnrlx960lii1cqijz1wr8q93i7m2z91h3v3w0j"))))
     (build-system gnu-build-system)
     (native-inputs
      (list autoconf automake))
     (inputs
      (list fftwf libfec))
     (arguments
-     `(;; For reproducibility, disable use of SSE3, SSE4.1, etc.
-       #:configure-flags '("--enable-simdoverride")
-       #:phases
-       (modify-phases %standard-phases
-         (add-after 'install 'delete-static-library
-           (lambda* (#:key outputs #:allow-other-keys)
-             (delete-file (string-append (assoc-ref outputs "out")
-                                         "/lib/libliquid.a")))))))
+     (list
+      ;; For reproducibility, disable use of SSE3, SSE4.1, etc.
+      #:configure-flags #~(list "--enable-simdoverride")
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'install 'delete-static-library
+            (lambda* (#:key outputs #:allow-other-keys)
+              (let ((version #$(version-major+minor
+                                (package-version this-package))))
+                (delete-file (string-append #$output
+                                            "/lib/libliquid.a."
+                                            version))))))))
     (home-page "https://liquidsdr.org")
     (synopsis "Signal processing library for software-defined radios")
     (description
diff --git a/gnu/packages/sagemath.scm b/gnu/packages/sagemath.scm
index 4542bc1c88..3d8c07b813 100644
--- a/gnu/packages/sagemath.scm
+++ b/gnu/packages/sagemath.scm
@@ -170,27 +170,6 @@ represented as strings.")
     (license license:public-domain)
     (home-page "https://github.com/miguelmarco/libhomfly")))
 
-;; Sage 9.1 doesn't build with ECL 20.  This won't be necessary once 9.2 is
-;; released.  See https://trac.sagemath.org/ticket/22191
-(define-public ecl-16
-  (package
-    (inherit ecl)
-    (version "16.1.3")
-    (source
-     (origin
-       (method url-fetch)
-       (uri (string-append
-             "https://common-lisp.net/project/ecl/static/files/release/ecl"
-             "-" version ".tgz"))
-       (sha256
-        (base32 "0m0j24w5d5a9dwwqyrg0d35c0nys16ijb4r0nyk87yp82v38b9bn"))
-       (patches (search-patches
-                  "ecl-16-libffi.patch"
-                  "ecl-16-ignore-stderr-write-error.patch"
-                  "ecl-16-format-directive-limit.patch"))))
-    ;; Current ECL uses LGPL 2.1+
-    (license license:lgpl2.0+)))
-
 (define-public pynac
   (package
     (name "pynac")
diff --git a/gnu/packages/security-token.scm b/gnu/packages/security-token.scm
index 307a0d4cb0..16099a4da7 100644
--- a/gnu/packages/security-token.scm
+++ b/gnu/packages/security-token.scm
@@ -891,7 +891,7 @@ phone is required.")
 (define-public libfido2
   (package
     (name "libfido2")
-    (version "1.11.0")
+    (version "1.12.0")
     (source
      (origin
        (method git-fetch)
@@ -899,21 +899,21 @@ phone is required.")
              (url "https://github.com/Yubico/libfido2")
              (commit version)))
        (file-name (git-file-name name version))
-       (sha256 (base32 "1nk4irmdg36930lgc892qmlmd4whz4fq37wknkdx5ap57i5x18i6"))))
+       (sha256 (base32 "123rysl21bmgk6rmpgg5s21a5ksmxnn1hc32ws88h7z0q4icvj87"))))
     (native-inputs (list pkg-config))
     (inputs (list eudev libcbor openssl zlib))
     (build-system cmake-build-system)
     (arguments
      (list
-       #:configure-flags
-       #~(list (string-append
-                 "-DPKG_CONFIG_EXECUTABLE="
-                 (search-input-file %build-inputs
-                                    (string-append
-                                      "/bin/" #$(pkg-config-for-target))))
-               (string-append "-DUDEV_RULES_DIR=" #$output "/lib/udev/rules.d"))
-       ;; regress tests enabled only for debug builds
-       #:tests? #f))
+      #:configure-flags
+      #~(list (string-append
+               "-DPKG_CONFIG_EXECUTABLE="
+               (search-input-file %build-inputs
+                                  (string-append
+                                   "/bin/" #$(pkg-config-for-target))))
+              (string-append "-DUDEV_RULES_DIR=" #$output "/lib/udev/rules.d"))
+      ;; regress tests enabled only for debug builds
+      #:tests? #f))
     (synopsis "Library functionality and command-line tools for FIDO devices")
     (description "libfido2 provides library functionality and command-line
 tools to communicate with a FIDO device over USB, and to verify attestation
diff --git a/gnu/packages/serialization.scm b/gnu/packages/serialization.scm
index 79c55e2b2f..8ab1efd311 100644
--- a/gnu/packages/serialization.scm
+++ b/gnu/packages/serialization.scm
@@ -578,27 +578,6 @@ object, without whitespace.")
 RPC system.  Think JSON, except binary.  Or think Protocol Buffers, except faster.")
     (license license:expat)))
 
-(define-public libbson
-  (package
-    (name "libbson")
-    (version "1.6.2")
-    (source
-      (origin
-        (method url-fetch)
-        (uri (string-append "https://github.com/mongodb/libbson/releases/"
-                             "download/" version "/libbson-" version ".tar.gz"))
-        (sha256
-         (base32
-          "1fj4554msq0rrz14snbj908dzqj46gh7jg9w9j0akn2b7q911m5a"))))
-    (build-system gnu-build-system)
-    (native-inputs (list perl))
-    (home-page "http://mongoc.org/libbson/current/index.html")
-    (synopsis "C BSON library")
-    (description "Libbson can create and parse BSON documents.  It can also
-convert JSON documents to BSON and the opposite.  BSON stands for Binary JSON,
-it is comparable to protobuf.")
-    (license license:asl2.0)))
-
 (define-public python-ruamel.yaml
   (package
     (name "python-ruamel.yaml")
diff --git a/gnu/packages/statistics.scm b/gnu/packages/statistics.scm
index 2d4dbe4a31..6196d6bd69 100644
--- a/gnu/packages/statistics.scm
+++ b/gnu/packages/statistics.scm
@@ -206,7 +206,7 @@ This package also provides @command{xls2csv} to export Excel files to CSV.")
 (define r-with-tests
   (package
     (name "r-with-tests")
-    (version "4.2.1")
+    (version "4.2.2")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://cran/src/base/R-"
@@ -214,7 +214,7 @@ This package also provides @command{xls2csv} to export Excel files to CSV.")
                                   version ".tar.gz"))
               (sha256
                (base32
-                "0gv4di1x835i4nsy21vqw66c0blmmmvyjkixc5a8x117dm4dnljd"))))
+                "1x9xjl6fyzs8r72zigirp905ki50wzyw9rxf7iqsbbsixi12pxhg"))))
     (build-system gnu-build-system)
     (arguments
      `(#:disallowed-references (,tzdata-for-tests)
@@ -310,7 +310,11 @@ as.POSIXct(if (\"\" != Sys.getenv(\"SOURCE_DATE_EPOCH\")) {\
                (("\\(2008\\)\n") "(2008) ")
                (("  ``Software") "``Software")
                (("Data Analysis:.") "Data Analysis:\n")
-               (("Programming with R") "  Programming with R"))))
+               (("Programming with R") "  Programming with R"))
+             (substitute* "src/library/tools/DESCRIPTION.in"
+               (("codetools, methods, xml2, curl, commonmark, knitr, xfun, mathjaxr")
+                "codetools, methods, xml2, curl, commonmark,
+    knitr, xfun, mathjaxr"))))
          (add-before 'build 'set-locales
            (lambda _
              (setlocale LC_ALL "C")
@@ -366,48 +370,48 @@ as.POSIXct(if (\"\" != Sys.getenv(\"SOURCE_DATE_EPOCH\")) {\
     ;; As the JDK is a rather large input with only very limited effects on R,
     ;; we decided to drop it.
     (native-inputs
-     `(("bzip2" ,bzip2)
-       ("perl" ,perl)
-       ("pkg-config" ,pkg-config)
-       ("texinfo" ,texinfo) ; for building HTML manuals
-       ("texlive" ,(texlive-updmap.cfg (list texlive-ae
-                                        texlive-inconsolata
-                                        texlive-fonts-ec
-                                        texlive-grfext
-                                        texlive-amsfonts
-                                        texlive-latex-base
-                                        texlive-latex-fancyvrb
-                                        texlive-latex-graphics
-                                        texlive-hyperref
-                                        texlive-oberdiek
-                                        texlive-latex-tools
-                                        texlive-latex-upquote
-                                        texlive-url
-                                        texlive-latex-xkeyval)))
-       ("tzdata" ,tzdata-for-tests)
-       ("xz" ,xz)))
+     (list bzip2
+           perl
+           pkg-config
+           texinfo                      ; for building HTML manuals
+           (texlive-updmap.cfg (list texlive-ae
+                                     texlive-inconsolata
+                                     texlive-fonts-ec
+                                     texlive-grfext
+                                     texlive-amsfonts
+                                     texlive-latex-base
+                                     texlive-latex-fancyvrb
+                                     texlive-latex-graphics
+                                     texlive-hyperref
+                                     texlive-oberdiek
+                                     texlive-latex-tools
+                                     texlive-latex-upquote
+                                     texlive-url
+                                     texlive-latex-xkeyval))
+           tzdata-for-tests
+           xz))
     (inputs
-     `(;; We need not only cairo here, but pango to ensure that tests for the
-       ;; "cairo" bitmapType plotting backend succeed.
-       ("pango" ,pango)
-       ("coreutils" ,coreutils)
-       ("curl" ,curl)
-       ("openblas" ,openblas)
-       ("gfortran" ,gfortran)
-       ("icu4c" ,icu4c)
-       ("libjpeg" ,libjpeg-turbo)
-       ("libpng" ,libpng)
-       ("libtiff" ,libtiff)
-       ("libxt" ,libxt)
-       ("pcre2" ,pcre2)
-       ("readline" ,readline)
-       ;; This avoids a reference to the ungraftable static bash.  R uses the
-       ;; detected shell for the "system" procedure.
-       ("bash" ,bash-minimal)
-       ("tcl" ,tcl)
-       ("tk" ,tk)
-       ("which" ,which)
-       ("zlib" ,zlib)))
+     (list coreutils
+           curl
+           openblas
+           gfortran
+           icu4c
+           libjpeg-turbo
+           libpng
+           libtiff
+           libxt
+           ;; We need not only cairo here, but pango to ensure that tests for the
+           ;; "cairo" bitmapType plotting backend succeed.
+           pango
+           pcre2
+           readline
+           tcl
+           tk
+           which
+           zlib
+           ;; This avoids a reference to the ungraftable static bash.  R uses the
+           ;; detected shell for the "system" procedure.
+           bash-minimal))
     (native-search-paths
      (list (search-path-specification
             (variable "R_LIBS_SITE")
@@ -448,29 +452,23 @@ available, greatly increasing its breadth and scope.")
                      (substitute* (string-append out "/lib/R/bin/libtool")
                        (((string-append
                           "(-L)?("
-                          (assoc-ref inputs "bzip2")
-                          "|"
-                          (assoc-ref inputs "perl")
-                          "|"
-                          (assoc-ref inputs "texlive")
-                          "|"
-                          (assoc-ref inputs "texlive-bin")
-                          "|"
-                          (assoc-ref inputs "texinfo")
-                          "|"
-                          (assoc-ref inputs "xz")
-                          "|"
                           (format #false
-                                  "/gnu/store/[^-]+-(~{~a~^|~})-[^/]+"
-                                  '("glibc-utf8-locales"
+                                  "~a/[^-]+-(~{~a~^|~})-[^/]+"
+                                  (%store-directory)
+                                  '("bzip2"
+                                    "file"
+                                    "glibc-utf8-locales"
+                                    "graphite2"
                                     "libselinux"
                                     "libsepol"
-                                    "file"
+                                    "perl"
+                                    "texinfo"
                                     "texlive-bin"
                                     "util-macros"
-                                    "graphite2"))
+                                    "xz"))
                           "|"
-                          "/gnu/store/[^-]+-glibc-[^-]+-static"
+                          (format #false "~a/[^-]+-glibc-[^-]+-static"
+                                  (%store-directory))
                           ")/lib")) ""))))))))))))
 
 (define-public rmath-standalone
@@ -1236,25 +1234,28 @@ using just two functions: melt and dcast (or acast).")
 (define-public r-ggplot2
   (package
     (name "r-ggplot2")
-    (version "3.3.6")
+    (version "3.4.0")
     (source
      (origin
        (method url-fetch)
        (uri (cran-uri "ggplot2" version))
        (sha256
-        (base32 "1aa377jdfajj8ld2fh159y8havlibsr4pjisf6mkzk8g5awlxjxz"))))
+        (base32 "0gj7n2y8msnmhk3x4r481biknvn2dqhahwazfqwr8f3lz599wbx8"))))
     (build-system r-build-system)
     (propagated-inputs
-     (list r-digest
+     (list r-cli
+           r-digest
            r-glue
            r-gtable
            r-isoband
+           r-lifecycle
            r-mass
            r-mgcv
            r-tibble
            r-rlang
            r-scales
            r-svglite ; Needed for 'ggsave'
+           r-vctrs
            r-withr))
     (native-inputs
      (list r-knitr))
diff --git a/gnu/packages/tex.scm b/gnu/packages/tex.scm
index 81f74f17df..a600bcae58 100644
--- a/gnu/packages/tex.scm
+++ b/gnu/packages/tex.scm
@@ -3993,6 +3993,47 @@ definitions.")
 
 (define-deprecated-package texlive-latex-amsmath texlive-amsmath)
 
+(define-public texlive-mathdots
+  (let ((template
+         (simple-texlive-package
+          "texlive-mathdots"
+          (list "doc/generic/mathdots/"
+                "source/generic/mathdots/"
+                "tex/generic/mathdots/")
+          (base32"1jaffj343p1chdxs2g7s6lpckvihk0jfw22nw0vmijyjxfiy9yg0"))))
+    (package
+      (inherit template)
+      (outputs '("out" "doc"))
+      (arguments
+       (substitute-keyword-arguments (package-arguments template)
+         ((#:tex-directory _ '())
+          "generic/mathdots")
+         ((#:build-targets _ '())
+          '(list "mathdots.ins"))
+         ((#:phases phases)
+          #~(modify-phases #$phases
+              (add-after 'unpack 'chdir
+                (lambda _
+                  (chdir "source/generic/mathdots")))
+              (replace 'copy-files
+                (lambda* (#:key inputs outputs #:allow-other-keys)
+                  (let ((origin (assoc-ref inputs "source"))
+                        (source (string-append (assoc-ref outputs "out")
+                                               "/share/texmf-dist/source"))
+                        (doc (string-append (assoc-ref outputs "doc")
+                                            "/share/texmf-dist/doc")))
+                    (copy-recursively (string-append origin "/source") source)
+                    (copy-recursively (string-append origin "/doc") doc))))))))
+      (home-page "https://ctan.org/macros/generic/mathdots")
+      (synopsis "Commands to produce dots in math that respect font size")
+      (description
+       "Mathdots redefines @code{\\ddots} and @code{\\vdots}, and defines
+@code{\\iddots}.  The dots produced by @code{\\iddots} slant in the opposite
+direction to @code{\\ddots}.  All the commands are designed to change size
+appropriately in scripts, as well as in response to LaTeX size changing
+commands.  The commands may also be used in plain TeX.")
+      (license license:lppl))))
+
 (define-public texlive-amscls
   (let ((template (simple-texlive-package
                    "texlive-amscls"
diff --git a/gnu/packages/text-editors.scm b/gnu/packages/text-editors.scm
index ed77113726..57341cd198 100644
--- a/gnu/packages/text-editors.scm
+++ b/gnu/packages/text-editors.scm
@@ -49,6 +49,7 @@
   #:use-module (guix build-system glib-or-gtk)
   #:use-module (guix build-system meson)
   #:use-module (guix build-system python)
+  #:use-module (guix build-system qt)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (gnu packages)
   #:use-module (gnu packages aspell)
@@ -59,6 +60,7 @@
   #:use-module (gnu packages code)
   #:use-module (gnu packages cpp)
   #:use-module (gnu packages crates-io)
+  #:use-module (gnu packages curl)
   #:use-module (gnu packages datastructures)
   #:use-module (gnu packages documentation)
   #:use-module (gnu packages fontutils)
@@ -895,6 +897,39 @@ Octave.  TeXmacs is completely extensible via Guile.")
     (license license:gpl3+)
     (home-page "https://www.texmacs.org/tmweb/home/welcome.en.html")))
 
+(define-public mogan
+  (package
+    (inherit texmacs)
+    (name "mogan")
+    (version "1.1.1")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/XmacsLabs/mogan")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "04wz6xmimjv2l6baxgzm8vyq5grg102m3l4wq8i6bglv529yp4ff"))))
+    (build-system qt-build-system)
+    (inputs
+     (modify-inputs (package-inputs texmacs)
+       ;; Replaced by S7 scheme
+       ;; TODO: Maybe unbundle S7
+       (delete "guile")
+       (prepend curl)))
+    (arguments
+     (substitute-keyword-arguments (package-arguments texmacs)
+       ((#:phases orig)
+        #~(modify-phases #$orig
+            ;; The non-deterministic compression issue is solved in Mogan.
+            (delete 'gzip-flags)))))
+    (home-page "https://github.com/XmacsLabs/mogan")
+    (synopsis "Scientific structural text editor")
+    (description
+     "Mogan is a scientific structural text editor, a fork of GNU TeXmacs.")
+    (license license:gpl3+)))
+
 (define-public textpieces
   (package
     (name "textpieces")
diff --git a/gnu/packages/tls.scm b/gnu/packages/tls.scm
index 3aceb349bf..f1e844b608 100644
--- a/gnu/packages/tls.scm
+++ b/gnu/packages/tls.scm
@@ -995,47 +995,6 @@ correct OpenSSL include path.  It is intended for use in your
 number generator")
   (license license:perl-license)))
 
-(define-public acme-client
-  (package
-    (name "acme-client")
-    (version "0.1.16")
-    (source (origin
-              (method url-fetch)
-              (uri (string-append "https://kristaps.bsd.lv/" name "/"
-                                  "snapshots/" name "-portable-"
-                                  version ".tgz"))
-              (sha256
-               (base32
-                "00q05b3b1dfnfp7sr1nbd212n0mqrycl3cr9lbs51m7ncaihbrz9"))))
-    (build-system gnu-build-system)
-    (arguments
-     '(#:tests? #f ; no test suite
-       #:make-flags
-       (list "CC=gcc"
-             (string-append "PREFIX=" (assoc-ref %outputs "out")))
-       #:phases
-       (modify-phases %standard-phases
-         (add-after 'unpack 'patch-paths
-           (lambda* (#:key inputs #:allow-other-keys)
-             (let ((pem (search-input-file inputs "/etc/ssl/cert.pem")))
-               (substitute* "http.c"
-                 (("/etc/ssl/cert.pem") pem))
-               #t)))
-         (delete 'configure)))) ; no './configure' script
-    (native-inputs
-     (list pkg-config))
-    (inputs
-     (list libbsd libressl))
-    (synopsis "Let's Encrypt client by the OpenBSD project")
-    (description "acme-client is a Let's Encrypt client implemented in C.  It
-uses a modular design, and attempts to secure itself by dropping privileges and
-operating in a chroot where possible.  acme-client is developed on OpenBSD and
-then ported to the GNU / Linux environment.")
-    (home-page "https://kristaps.bsd.lv/acme-client/")
-    ;; acme-client is distributed under the ISC license, but the files 'jsmn.h'
-    ;; and 'jsmn.c' are distributed under the Expat license.
-    (license (list license:isc license:expat))))
-
 ;; The "-apache" variant is the upstreamed prefered variant. A "-gpl"
 ;; variant exists in addition to the "-apache" one.
 (define-public mbedtls-apache
diff --git a/gnu/packages/video.scm b/gnu/packages/video.scm
index 19ca1d8267..b6c8b8ed1c 100644
--- a/gnu/packages/video.scm
+++ b/gnu/packages/video.scm
@@ -2221,6 +2221,7 @@ SVCD, DVD, 3ivx, DivX 3/4/5, WMV and H.264 movies.")
            libxext
            libxkbcommon
            libxinerama
+           libxpresent
            libxrandr
            libxscrnsaver
            libxv
diff --git a/gnu/packages/web-browsers.scm b/gnu/packages/web-browsers.scm
index 31885fcbe0..51c0f68680 100644
--- a/gnu/packages/web-browsers.scm
+++ b/gnu/packages/web-browsers.scm
@@ -705,7 +705,7 @@ is fully configurable and extensible in Common Lisp.")
 (define-public lagrange
   (package
     (name "lagrange")
-    (version "1.13.8")
+    (version "1.14.0")
     (source
      (origin
        (method url-fetch)
@@ -713,7 +713,7 @@ is fully configurable and extensible in Common Lisp.")
         (string-append "https://git.skyjake.fi/skyjake/lagrange/releases/"
                        "download/v" version "/lagrange-" version ".tar.gz"))
        (sha256
-        (base32 "1l6cfvmmw2g30qsxmn5jma17kxgmfknlgji4pbdj1flv8p73bvza"))
+        (base32 "08qb8f0j3sdbrkr4zsy5pcpqz2cy520q6vb8vq7ilkbz0yfxmgf2"))
        (modules '((guix build utils)))
        (snippet
         '(begin
diff --git a/gnu/packages/web.scm b/gnu/packages/web.scm
index c1db7b1235..87ed717b9e 100644
--- a/gnu/packages/web.scm
+++ b/gnu/packages/web.scm
@@ -5849,13 +5849,13 @@ deployments.")
   (package
     (name "varnish")
     (home-page "https://varnish-cache.org/")
-    (version "7.1.1")
+    (version "7.2.1")
     (source (origin
               (method url-fetch)
               (uri (string-append home-page "_downloads/varnish-" version ".tgz"))
               (sha256
                (base32
-                "14512fjjzwini3fics6sib9y83s45vlrpncamixqmmg7j0jvxbrc"))))
+                "0h590kr7rhp57a4kfx6apyvqk60w78qdjwpr6g2ikv5840bpv4sd"))))
     (build-system gnu-build-system)
     (arguments
      `(#:configure-flags (list (string-append "LDFLAGS=-Wl,-rpath=" %output "/lib")
diff --git a/gnu/packages/xdisorg.scm b/gnu/packages/xdisorg.scm
index 298e6f3e47..1a4d805f19 100644
--- a/gnu/packages/xdisorg.scm
+++ b/gnu/packages/xdisorg.scm
@@ -1140,19 +1140,19 @@ transparent text on your screen.")
 (define-public wob
   (package
     (name "wob")
-    (version "0.13")
+    (version "0.14.2")
     (source
      (origin
        (method url-fetch)
        (uri (string-append "https://github.com/francma/wob/releases/download/"
                            version "/wob-" version ".tar.gz"))
        (sha256
-        (base32 "0i8y6kq37qcgdq85ll4rapisjl7zw6aa11yx2f2xw2d3j93kdxh8"))))
+        (base32 "12s9pc0dhqgawq6jiqhamj1zq9753kgpswny1rcsdx1lkpzrgaq1"))))
     (build-system meson-build-system)
     (native-inputs
      (list pkg-config scdoc))
     (inputs
-     (list libseccomp wayland wayland-protocols))
+     (list libinih libseccomp wayland wayland-protocols))
     (home-page "https://github.com/francma/wob")
     (synopsis "Lightweight overlay bar for Wayland")
     (description
diff --git a/gnu/packages/xfce.scm b/gnu/packages/xfce.scm
index 6840867612..720a36e3b9 100644
--- a/gnu/packages/xfce.scm
+++ b/gnu/packages/xfce.scm
@@ -681,7 +681,7 @@ allows you to shut down the computer from Xfce.")
 (define-public xfce4-settings
   (package
     (name "xfce4-settings")
-    (version "4.16.4")
+    (version "4.16.5")
     (source (origin
               (method url-fetch)
               (uri (string-append "https://archive.xfce.org/src/xfce/"
@@ -689,7 +689,7 @@ allows you to shut down the computer from Xfce.")
                                   name "-" version ".tar.bz2"))
               (sha256
                (base32
-                "1vd3l20myjfbq53x8sywy989zd557adyv3bb2y0nhh2is8ps9aqq"))
+                "13nj80mshkz3czrp8l1yxj6qmz0kkfhzv94z3ixfgmw64j078kvs"))
               (patches (search-patches "xfce4-settings-defaults.patch"))))
     (build-system gnu-build-system)
     (arguments
@@ -1335,7 +1335,7 @@ of data to either CD/DVD/BD.")
 (define-public xfce4-screenshooter
   (package
    (name "xfce4-screenshooter")
-   (version "1.9.11")
+   (version "1.10.0")
    (source (origin
             (method url-fetch)
             (uri (string-append "https://archive.xfce.org/src/apps/"
@@ -1345,7 +1345,7 @@ of data to either CD/DVD/BD.")
                                 version ".tar.bz2"))
             (sha256
              (base32
-              "1d7qyc2w4962crmkz5n0mma2qmyp9hhq455karyzacjbb6z0cgg7"))))
+              "0lvv6iam348n7l3md94lanxyyn87xmrivzdvfi0fa3vgjfk88j56"))))
    (build-system gnu-build-system)
    (native-inputs
     (list pkg-config intltool
diff --git a/gnu/packages/xorg.scm b/gnu/packages/xorg.scm
index a6b7b71d1d..7767a35afe 100644
--- a/gnu/packages/xorg.scm
+++ b/gnu/packages/xorg.scm
@@ -1217,7 +1217,7 @@ hit when running single-threaded.")
             "1p0flwb67xawyv6yhri9w17m1i4lji5qnd0gq8v1vsfb8zw7rw15"))))
     (build-system gnu-build-system)
     (inputs
-      (list xorgproto libxext libx11))
+      (list xorgproto libxext libx11 windowswmproto))
     (native-inputs
       (list pkg-config))
     (home-page "https://www.x.org/wiki/")
diff --git a/guix/build-system/r.scm b/guix/build-system/r.scm
index 620822b870..9b360ae581 100644
--- a/guix/build-system/r.scm
+++ b/guix/build-system/r.scm
@@ -61,7 +61,7 @@ release corresponding to NAME and VERSION."
                          "/src/contrib/"
                          name "_" version ".tar.gz")
           ;; TODO: use %bioconductor-version from (guix import cran)
-          (string-append "https://bioconductor.org/packages/3.15"
+          (string-append "https://bioconductor.org/packages/3.16"
                          type-url-part
                          "/src/contrib/"
                          name "_" version ".tar.gz"))))
diff --git a/guix/build/syscalls.scm b/guix/build/syscalls.scm
index 61926beb80..2a12567b15 100644
--- a/guix/build/syscalls.scm
+++ b/guix/build/syscalls.scm
@@ -51,6 +51,7 @@
             MS_RELATIME
             MS_BIND
             MS_MOVE
+            MS_REC
             MS_SHARED
             MS_LAZYTIME
             MNT_FORCE
@@ -541,6 +542,7 @@ the last argument of `mknod'."
 (define MS_NODIRATIME      2048)
 (define MS_BIND            4096)
 (define MS_MOVE            8192)
+(define MS_REC            16384)
 (define MS_SHARED       1048576)
 (define MS_RELATIME     2097152)
 (define MS_STRICTATIME 16777216)
diff --git a/guix/import/cran.scm b/guix/import/cran.scm
index 278743d496..286a4c21b9 100644
--- a/guix/import/cran.scm
+++ b/guix/import/cran.scm
@@ -188,9 +188,9 @@ package definition."
 (define %cran-canonical-url "https://cran.r-project.org/package=")
 (define %bioconductor-url "https://bioconductor.org/packages/")
 
-;; The latest Bioconductor release is 3.15.  Bioconductor packages should be
+;; The latest Bioconductor release is 3.16.  Bioconductor packages should be
 ;; updated together.
-(define %bioconductor-version "3.15")
+(define %bioconductor-version "3.16")
 
 (define* (bioconductor-packages-list-url #:optional type)
   (string-append "https://bioconductor.org/packages/"
diff --git a/guix/inferior.scm b/guix/inferior.scm
index 2fe34ca0dc..defdcc4e48 100644
--- a/guix/inferior.scm
+++ b/guix/inferior.scm
@@ -69,6 +69,8 @@
             inferior-exception-arguments
             inferior-exception-inferior
             inferior-exception-stack
+            inferior-protocol-error?
+            inferior-protocol-error-inferior
             read-repl-response
 
             inferior-packages
@@ -314,6 +316,10 @@ equivalent.  Return #f if the inferior could not be launched."
   (inferior   inferior-exception-inferior)        ;<inferior> | #f
   (stack      inferior-exception-stack))          ;list of (FILE COLUMN LINE)
 
+(define-condition-type &inferior-protocol-error &error
+  inferior-protocol-error?
+  (inferior  inferior-protocol-error-inferior))   ;<inferior>
+
 (define* (read-repl-response port #:optional inferior)
   "Read a (guix repl) response from PORT and return it as a Scheme object.
 Raise '&inferior-exception' when an exception is read from PORT."
@@ -339,7 +345,11 @@ Raise '&inferior-exception' when an exception is read from PORT."
      (raise (condition (&inferior-exception
                         (arguments (cons key (map sexp->object objects)))
                         (inferior inferior)
-                        (stack '())))))))
+                        (stack '())))))
+    (_
+     ;; Protocol error.
+     (raise (condition (&inferior-protocol-error
+                        (inferior inferior)))))))
 
 (define (read-inferior-response inferior)
   (read-repl-response (inferior-socket inferior)
diff --git a/guix/licenses.scm b/guix/licenses.scm
index 80cf0f1114..632c9174df 100644
--- a/guix/licenses.scm
+++ b/guix/licenses.scm
@@ -57,6 +57,7 @@
             edl1.0
             epl1.0
             epl2.0
+            eupl1.1
             eupl1.2
             expat expat-0
             freetype
@@ -344,6 +345,11 @@ at URI, which may be a file:// URI pointing the package's tree."
            "https://www.eclipse.org/legal/epl-2.0/"
            "https://www.gnu.org/licenses/license-list#EPL2"))
 
+(define eupl1.1
+  (license "EUPL 1.1"
+           "https://directory.fsf.org/wiki/License:EUPL-1.1"
+           "https://www.gnu.org/licenses/license-list#EUPL-1.1"))
+
 (define eupl1.2
   (license "EUPL 1.2"
            "https://directory.fsf.org/wiki/License:EUPL-1.2"
diff --git a/guix/packages.scm b/guix/packages.scm
index 704b4ee710..502df7fdd1 100644
--- a/guix/packages.scm
+++ b/guix/packages.scm
@@ -1176,9 +1176,9 @@ inputs of Coreutils and adds libcap:
 
   (modify-inputs (package-inputs coreutils)
     (delete \"gmp\" \"acl\")
-    (append libcap))
+    (prepend libcap))
 
-Other types of clauses include 'prepend' and 'replace'.
+Other types of clauses include 'append' and 'replace'.
 
 The first argument must be a labeled input list; the result is also a labeled
 input list."
diff --git a/guix/scripts/offload.scm b/guix/scripts/offload.scm
index 925325ef5f..578b3b9888 100644
--- a/guix/scripts/offload.scm
+++ b/guix/scripts/offload.scm
@@ -25,7 +25,7 @@
   #:autoload   (ssh auth) (userauth-public-key!)
   #:autoload   (ssh session) (make-session
                               connect! get-error
-                              disconnect! session-set!)
+                              disconnect! session-set! session-get)
   #:autoload   (ssh version) (zlib-support?)
   #:use-module (guix config)
   #:use-module (guix records)
@@ -34,7 +34,8 @@
                            send-files retrieve-files retrieve-files*
                            remote-inferior report-guile-error)
   #:use-module (guix store)
-  #:autoload   (guix inferior) (inferior-eval close-inferior inferior?)
+  #:autoload   (guix inferior) (inferior-eval close-inferior
+                                inferior? inferior-protocol-error?)
   #:autoload   (guix derivations) (read-derivation-from-file
                                    derivation-file-name
                                    build-derivations)
@@ -111,7 +112,7 @@
   ;; A #f value tells the offload scheduler to disregard the load of the build
   ;; machine when selecting the best offload machine.
   (overload-threshold build-machine-overload-threshold ; inexact real between
-                      (default 0.6))                   ; 0.0 and 1.0 | #f
+                      (default 0.8))                   ; 0.0 and 1.0 | #f
   (parallel-builds build-machine-parallel-builds  ; number
                    (default 1))
   (speed           build-machine-speed            ; inexact real
@@ -473,6 +474,15 @@ logical cores available, to give a rough estimation of CPU usage.  Return
               (vector-set! vec j (vector-ref vec (- i 1)))
               (loop (cons val result) (- i 1))))))))
 
+(define (remote-inferior* session)
+  "Like 'remote-inferior', but upon error return #f."
+  (or (guard (c ((inferior-protocol-error? c) #f))
+        (remote-inferior session))
+      (begin
+        (warning (G_ "failed to run 'guix repl' on machine '~a'~%")
+                 (session-get session 'host))
+        #f)))
+
 (define (choose-build-machine machines)
   "Return two values: the best machine among MACHINES and its build
 slot (which must later be released with 'release-build-slot'), or #f and #f."
@@ -511,7 +521,7 @@ slot (which must later be released with 'release-build-slot'), or #f and #f."
        ;; too costly to call it once for every machine.
        (let* ((session (false-if-exception (open-ssh-session best
                                                              %short-timeout)))
-              (node    (and session (remote-inferior session)))
+              (node    (and session (remote-inferior* session)))
               (load    (and node (node-load node)))
               (threshold (build-machine-overload-threshold best))
               (space   (and node (node-free-disk-space node))))
@@ -708,6 +718,11 @@ machine."
     (and (string=? (build-machine-name m1) (build-machine-name m2))
          (= (build-machine-port m1) (build-machine-port m2))))
 
+  (define (if-true proc)
+    (lambda args
+      (when (every ->bool args)
+        (apply proc args))))
+
   ;; A given build machine may appear several times (e.g., once for
   ;; "x86_64-linux" and a second time for "i686-linux"); test them only once.
   (let ((machines (filter pred
@@ -718,12 +733,12 @@ machine."
     (let* ((names    (map build-machine-name machines))
            (sockets  (map build-machine-daemon-socket machines))
            (sessions (map (cut open-ssh-session <> %short-timeout) machines))
-           (nodes    (map remote-inferior sessions)))
-      (for-each assert-node-has-guix nodes names)
-      (for-each assert-node-repl nodes names)
-      (for-each assert-node-can-import sessions nodes names sockets)
-      (for-each assert-node-can-export sessions nodes names sockets)
-      (for-each close-inferior nodes)
+           (nodes    (map remote-inferior* sessions)))
+      (for-each (if-true assert-node-has-guix) nodes names)
+      (for-each (if-true assert-node-repl) nodes names)
+      (for-each (if-true assert-node-can-import) sessions nodes names sockets)
+      (for-each (if-true assert-node-can-export) sessions nodes names sockets)
+      (for-each (if-true close-inferior) nodes)
       (for-each disconnect! sessions))))
 
 (define (check-machine-status machine-file pred)
@@ -743,10 +758,9 @@ machine."
                 (define session
                   (open-ssh-session machine %short-timeout))
 
-                (match (remote-inferior session)
+                (match (remote-inferior* session)
                   (#f
-                   (warning (G_ "failed to run 'guix repl' on machine '~a'~%")
-                            (build-machine-name machine)))
+                   #f)
                   ((? inferior? inferior)
                    (let ((now (car (gettimeofday))))
                      (match (inferior-eval '(list (uname)
diff --git a/guix/scripts/style.scm b/guix/scripts/style.scm
index c0b9ea1a28..fa7175fb16 100644
--- a/guix/scripts/style.scm
+++ b/guix/scripts/style.scm
@@ -335,13 +335,15 @@ PACKAGE."
 
 (define* (format-whole-file file #:rest rest)
   "Reformat all of FILE."
-  (let ((lst (call-with-input-file file read-with-comments/sequence)))
-    (with-atomic-file-output file
-      (lambda (port)
-        (apply pretty-print-with-comments/splice port lst
-               #:format-comment canonicalize-comment
-               #:format-vertical-space canonicalize-vertical-space
-               rest)))))
+  (with-fluids ((%default-port-encoding "UTF-8"))
+    (let ((lst (call-with-input-file file read-with-comments/sequence
+                                     #:guess-encoding #t)))
+      (with-atomic-file-output file
+        (lambda (port)
+          (apply pretty-print-with-comments/splice port lst
+                 #:format-comment canonicalize-comment
+                 #:format-vertical-space canonicalize-vertical-space
+                 rest))))))
 
 
 ;;;
diff --git a/guix/scripts/system/reconfigure.scm b/guix/scripts/system/reconfigure.scm
index afd410d4bc..544aacfef4 100644
--- a/guix/scripts/system/reconfigure.scm
+++ b/guix/scripts/system/reconfigure.scm
@@ -40,9 +40,9 @@
   #:use-module (guix diagnostics)
   #:use-module (ice-9 match)
   #:use-module (srfi srfi-1)
-  #:use-module (srfi srfi-11)
   #:use-module (srfi srfi-34)
   #:use-module (srfi srfi-35)
+  #:use-module (srfi srfi-71)
   #:use-module ((guix config) #:select (%guix-package-name))
   #:export (switch-system-program
             switch-to-system
@@ -184,8 +184,8 @@ services as defined by OS."
                      #:target-type shepherd-root-service-type))))
 
   (mlet* %store-monad ((live-services (running-services eval)))
-    (let*-values (((to-unload to-restart)
-                   (shepherd-service-upgrade live-services target-services)))
+    (let ((to-unload to-restart
+                     (shepherd-service-upgrade live-services target-services)))
       (let* ((to-unload  (map live-service-canonical-name to-unload))
              (to-restart (map shepherd-service-canonical-name to-restart))
              (running    (map live-service-canonical-name
@@ -347,14 +347,12 @@ to commits of channels in NEW."
                                         (channel-name old)))
                                  new)))
                   (and new
-                       (let-values (((checkout commit relation)
-                                     (update-cached-checkout
-                                      (channel-url new)
-                                      #:ref
-                                      `(commit . ,(channel-commit new))
-                                      #:starting-commit
-                                      (channel-commit old)
-                                      #:check-out? #f)))
+                       (let ((checkout commit relation
+                                       (update-cached-checkout
+                                        (channel-url new)
+                                        #:ref `(commit . ,(channel-commit new))
+                                        #:starting-commit (channel-commit old)
+                                        #:check-out? #f)))
                          (list new
                                (channel-commit old) (channel-commit new)
                                relation)))))